메뉴 건너뛰기




Volumn 26, Issue 10, 2016, Pages 1675-1686

Functional probiotic characterization and in vivo cholesterol-lowering activity of lactobacillus helveticus isolated from fermented cow milk

Author keywords

Antihypertensive; Bioactive peptide; Cholesterol lowering; Lactobacillus helveticus; Probiotics

Indexed keywords

AMPICILLIN; CHLORAMPHENICOL; CHOLESTEROL; CLINDAMYCIN; ERYTHROMYCIN; GENTAMICIN; HYPOCHOLESTEROLEMIC AGENT; ISOLEUCYL PROLYL PROLINE; KANAMYCIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PROBIOTIC AGENT; PROLINE DERIVATIVE; STREPTOMYCIN; TETRACYCLINE; TRIPEPTIDE; UNCLASSIFIED DRUG; VALYL PROLYL PROLINE; VANCOMYCIN;

EID: 84992448369     PISSN: 10177825     EISSN: 17388872     Source Type: Journal    
DOI: 10.4014/jmb.1603.03005     Document Type: Article
Times cited : (45)

References (54)
  • 2
    • 84890573205 scopus 로고    scopus 로고
    • Protective effect of Sam-Hwang-Sa-Sim-Tang against hepatic steatosis in mice fed a high-cholesterol diet
    • Ahn T-G, Lee J-Y, Cheon S-Y, An H-J, Kook Y-B. 2013. Protective effect of Sam-Hwang-Sa-Sim-Tang against hepatic steatosis in mice fed a high-cholesterol diet. BMC Complement. Altern. Med. 13: 366.
    • (2013) BMC Complement. Altern. Med , vol.13 , pp. 366
    • Ahn, T.-G.1    Lee, J.-Y.2    Cheon, S.-Y.3    An, H.-J.4    Kook, Y.-B.5
  • 3
    • 34047177832 scopus 로고    scopus 로고
    • Antibiotic resistance in non-enterococcal lactic acid bacteria and bifidobacteria
    • Ammor MS, Florez AB, Mayo B. 2007. Antibiotic resistance in non-enterococcal lactic acid bacteria and bifidobacteria. Food Microbiol. 24: 559-570.
    • (2007) Food Microbiol , vol.24 , pp. 559-570
    • Ammor, M.S.1    Florez, A.B.2    Mayo, B.3
  • 5
    • 0041573068 scopus 로고    scopus 로고
    • Bile tolerance, bile deconjugation and cholesterol reducing properties of dietary lactobacilli
    • Ashar MN, Prajapati JB. 1998. Bile tolerance, bile deconjugation and cholesterol reducing properties of dietary lactobacilli. Ind. J. Microbiol. 38: 145-148.
    • (1998) Ind. J. Microbiol , vol.38 , pp. 145-148
    • Ashar, M.N.1    Prajapati, J.B.2
  • 6
    • 0034572483 scopus 로고    scopus 로고
    • Verification of hypocholesterolemic effect of fermented milk on human subjects with different cholesterol levels
    • Ashar MN, Prajapati JB. 2000. Verification of hypocholesterolemic effect of fermented milk on human subjects with different cholesterol levels. Folia Microbiol. 45: 263-268.
    • (2000) Folia Microbiol , vol.45 , pp. 263-268
    • Ashar, M.N.1    Prajapati, J.B.2
  • 7
    • 33747095365 scopus 로고    scopus 로고
    • In vitro antibacterial activity of Lactobacillus helveticus strain KS300 against diarrhoeagenic, uropathogenic and vaginosisassociated bacteria
    • Atassi F, Brassart D, Grob P, Graf F, Servin AL. 2006. In vitro antibacterial activity of Lactobacillus helveticus strain KS300 against diarrhoeagenic, uropathogenic and vaginosisassociated bacteria. J. Appl. Microbiol. 101: 647-654.
    • (2006) J. Appl. Microbiol , vol.101 , pp. 647-654
    • Atassi, F.1    Brassart, D.2    Grob, P.3    Graf, F.4    Servin, A.L.5
  • 9
    • 0030941803 scopus 로고    scopus 로고
    • The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
    • Brown MS, Goldstein JL. 1997. The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89: 331-340.
    • (1997) Cell , vol.89 , pp. 331-340
    • Brown, M.S.1    Goldstein, J.L.2
  • 10
    • 29144442497 scopus 로고    scopus 로고
    • Functional analysis of putative adhesion factors in Lactobacillus acidophilus NCFM
    • Buck BL, Altermann E, Svingerud T, Klaenhammer TR. 2005. Functional analysis of putative adhesion factors in Lactobacillus acidophilus NCFM. Appl. Environ. Microbiol. 71: 8344-8351.
    • (2005) Appl. Environ. Microbiol , vol.71 , pp. 8344-8351
    • Buck, B.L.1    Altermann, E.2    Svingerud, T.3    Klaenhammer, T.R.4
  • 11
  • 13
    • 0017120248 scopus 로고
    • Silicic acid thin-layer chromatography of conjugated and free bile acids
    • Chavez MN, Krone CL. 1976. Silicic acid thin-layer chromatography of conjugated and free bile acids. J. Lipid Res. 17: 545-547.
    • (1976) J. Lipid Res , vol.17 , pp. 545-547
    • Chavez, M.N.1    Krone, C.L.2
  • 14
    • 84920047203 scopus 로고    scopus 로고
    • Fermented milk of Lactobacillus helveticus IDCC3801 improves cognitive functioning during cognitive fatigue tests in healthy older adults
    • Chung Y-C, Jin H-M, Cui Y, Kim DS, Jung JM, Park J-I, et al. 2014. Fermented milk of Lactobacillus helveticus IDCC3801 improves cognitive functioning during cognitive fatigue tests in healthy older adults. J. Funct. Foods 10: 465-474.
    • (2014) J. Funct. Foods , vol.10 , pp. 465-474
    • Chung, Y.-C.1    Jin, H.-M.2    Cui, Y.3    Kim, D.S.4    Jung, J.M.5    Park, J.-I.6
  • 15
    • 40749089608 scopus 로고    scopus 로고
    • Balancing cholesterol synthesis and absorption in the gastrointestinal tract
    • Cohen DE. 2008. Balancing cholesterol synthesis and absorption in the gastrointestinal tract. J. Clin. Lipidol. 2: S1-S3.
    • (2008) J. Clin. Lipidol , vol.2 , pp. S1-S3
    • Cohen, D.E.1
  • 16
    • 84940978957 scopus 로고    scopus 로고
    • Preliminary probiotic and technological characterization of Pediococcus pentosaceus strain KID7 and in vivo assessment of its cholesterol-lowering activity
    • Damodharan K, Lee YS, Palaniyandi SA, Yang SH, Suh JW. 2015. Preliminary probiotic and technological characterization of Pediococcus pentosaceus strain KID7 and in vivo assessment of its cholesterol-lowering activity. Front. Microbiol. 6: 768.
    • (2015) Front. Microbiol , vol.6 , pp. 768
    • Damodharan, K.1    Lee, Y.S.2    Palaniyandi, S.A.3    Yang, S.H.4    Suh, J.W.5
  • 17
    • 84898023722 scopus 로고    scopus 로고
    • Microbiota modification with probiotics induces hepatic bile acid synthesis via downregulation of the Fxr Fgf15 axis in mice
    • Degirolamo C, Rainaldi S, Bovenga F, Murzilli S, Moschetta A. 2014. Microbiota modification with probiotics induces hepatic bile acid synthesis via downregulation of the Fxr Fgf15 axis in mice. Cell Rep. 7: 12-18.
    • (2014) Cell Rep , vol.7 , pp. 12-18
    • Degirolamo, C.1    Rainaldi, S.2    Bovenga, F.3    Murzilli, S.4    Moschetta, A.5
  • 18
    • 84919761808 scopus 로고    scopus 로고
    • Characterization of the adhesive factors of selected probiotics to Caco-2 epithelium cell line
    • Dimitrov Z, Gotova I, Chorbadjiyska E. 2014. Characterization of the adhesive factors of selected probiotics to Caco-2 epithelium cell line. Biotechnol. Biotechnol. Equip. 28: 1079-1083.
    • (2014) Biotechnol. Biotechnol. Equip , vol.28 , pp. 1079-1083
    • Dimitrov, Z.1    Gotova, I.2    Chorbadjiyska, E.3
  • 19
    • 85078066318 scopus 로고    scopus 로고
    • Guidance on the assessment of bacterial susceptibility to antimicrobials of human and veterinary importance
    • EFSA
    • EFSA. 2012. Guidance on the assessment of bacterial susceptibility to antimicrobials of human and veterinary importance. EFSA J. 10: 2740.
    • (2012) EFSA J , vol.10 , pp. 2740
  • 20
    • 43949127930 scopus 로고    scopus 로고
    • The introduction of a qualified presumption of safety (QPS) approach for assessment of selected microorganisms referred to EFSA
    • EFSA
    • EFSA. 2007. The introduction of a qualified presumption of safety (QPS) approach for assessment of selected microorganisms referred to EFSA. EFSA J. 587: 1-16.
    • (2007) EFSA J , vol.587 , pp. 1-16
  • 22
    • 0031914928 scopus 로고    scopus 로고
    • Lactobacillus helveticus heterogeneity in natural cheese starters: The diversity in phenotypic characteristics
    • Fortina MG, Nicastro G, Carminati D, Neviani E, Manachini PL. 1998. Lactobacillus helveticus heterogeneity in natural cheese starters: the diversity in phenotypic characteristics. J. Appl. Microbiol. 84: 72-80.
    • (1998) J. Appl. Microbiol , vol.84 , pp. 72-80
    • Fortina, M.G.1    Nicastro, G.2    Carminati, D.3    Neviani, E.4    Manachini, P.L.5
  • 23
    • 0015348189 scopus 로고
    • Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
    • Friedewald WT, Levy RI, Fredrickson DS. 1972. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin. Chem. 18: 499-502.
    • (1972) Clin. Chem , vol.18 , pp. 499-502
    • Friedewald, W.T.1    Levy, R.I.2    Fredrickson, D.S.3
  • 24
    • 84885733173 scopus 로고    scopus 로고
    • Novel probiotic-fermented milk with angiotensin I-converting enzyme inhibitory peptides produced by Bifidobacterium bifidum MF 20/5
    • Gonzalez-Gonzalez C, Gibson T, Jauregi P. 2013. Novel probiotic-fermented milk with angiotensin I-converting enzyme inhibitory peptides produced by Bifidobacterium bifidum MF 20/5. Int. J. Food Microbiol. 167: 131-137.
    • (2013) Int. J. Food Microbiol , vol.167 , pp. 131-137
    • Gonzalez-Gonzalez, C.1    Gibson, T.2    Jauregi, P.3
  • 25
    • 33745610779 scopus 로고    scopus 로고
    • Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries in a case-control study based on the INTERHEART study
    • Gyarfas I, Keltai M, Salim Y. 2006. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries in a case-control study based on the INTERHEART study. Orv. Hetil. 147: 675-686.
    • (2006) Orv. Hetil , vol.147 , pp. 675-686
    • Gyarfas, I.1    Keltai, M.2    Salim, Y.3
  • 26
    • 84905675648 scopus 로고    scopus 로고
    • Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic
    • Hill C, Guarner F, Reid G, Gibson GR, Merenstein DJ, Pot B, et al. 2014. Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nat. Rev. Gastroenterol. Hepatol. 11: 506-514.
    • (2014) Nat. Rev. Gastroenterol. Hepatol , vol.11 , pp. 506-514
    • Hill, C.1    Guarner, F.2    Reid, G.3    Gibson, G.R.4    Merenstein, D.J.5    Pot, B.6
  • 27
    • 81255195785 scopus 로고    scopus 로고
    • LC-MS/MS quantification of bioactive angiotensin I-converting enzyme inhibitory peptides in rye malt sourdoughs
    • Hu Y, Stromeck A, Loponen J, Lopes-Lutz D, Schieber A, Ganzle MG. 2011. LC-MS/MS quantification of bioactive angiotensin I-converting enzyme inhibitory peptides in rye malt sourdoughs. J. Agric. Food Chem. 59: 11983-11989.
    • (2011) J. Agric. Food Chem , vol.59 , pp. 11983-11989
    • Hu, Y.1    Stromeck, A.2    Loponen, J.3    Lopes-Lutz, D.4    Schieber, A.5    Ganzle, M.G.6
  • 28
    • 73449109457 scopus 로고    scopus 로고
    • Mechanisms of cholesterol removal by lactobacilli under conditions that mimic the human gastrointestinal tract
    • Lye HS, Rahmat-Ali GR, Liong M-T. 2010. Mechanisms of cholesterol removal by lactobacilli under conditions that mimic the human gastrointestinal tract. Int. Diary J. 20: 169-175.
    • (2010) Int. Diary J , vol.20 , pp. 169-175
    • Lye, H.S.1    Rahmat-Ali, G.R.2    Liong, M.-T.3
  • 29
    • 84893942130 scopus 로고    scopus 로고
    • Peptidoglycan hydrolases as species-specific markers to differentiate Lactobacillus helveticus from Lactobacillus gallinarum and other closely related homofermentative lactobacilli
    • Jebava I, Chuat V, Lortal S, Valence F. 2014. Peptidoglycan hydrolases as species-specific markers to differentiate Lactobacillus helveticus from Lactobacillus gallinarum and other closely related homofermentative lactobacilli. Curr. Microbiol. 68: 551-557.
    • (2014) Curr. Microbiol , vol.68 , pp. 551-557
    • Jebava, I.1    Chuat, V.2    Lortal, S.3    Valence, F.4
  • 30
    • 77951665890 scopus 로고    scopus 로고
    • Diversity of bile salt hydrolase activities in different lactobacilli toward human bile salts
    • Jiang J, Hang X, Zhang M, Liu X, Li D, Yang H. 2010. Diversity of bile salt hydrolase activities in different lactobacilli toward human bile salts. Ann. Microbiol. 60: 81-88.
    • (2010) Ann. Microbiol , vol.60 , pp. 81-88
    • Jiang, J.1    Hang, X.2    Zhang, M.3    Liu, X.4    Li, D.5    Yang, H.6
  • 31
    • 51649086648 scopus 로고    scopus 로고
    • Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome
    • Jones BV, Begley M, Hill C, Gahan CG, Marchesi JR. 2008. Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome. Proc. Natl. Acad. Sci. USA 105: 13580-13585.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 13580-13585
    • Jones, B.V.1    Begley, M.2    Hill, C.3    Gahan, C.G.4    Marchesi, J.R.5
  • 32
    • 78049480111 scopus 로고    scopus 로고
    • Antibacterial activity of Lactobacillus acidophilus and Lactobacillus casei against methicillin-resistant Staphylococcus aureus (MRSA)
    • Karska-Wysocki B, Bazo M, Smoragiewicz W. 2010. Antibacterial activity of Lactobacillus acidophilus and Lactobacillus casei against methicillin-resistant Staphylococcus aureus (MRSA). Microbiol. Res. 165: 674-686.
    • (2010) Microbiol. Res , vol.165 , pp. 674-686
    • Karska-Wysocki, B.1    Bazo, M.2    Smoragiewicz, W.3
  • 34
    • 33747503962 scopus 로고    scopus 로고
    • Bioactive peptides: Production and functionality
    • Korhonen H, Pihlanto A. 2006. Bioactive peptides: production and functionality. Int. Dairy J. 16: 945-960.
    • (2006) Int. Dairy J , vol.16 , pp. 945-960
    • Korhonen, H.1    Pihlanto, A.2
  • 35
    • 0037307257 scopus 로고    scopus 로고
    • Antihypertensive effect of sour milk and peptides isolated from it that are inhibitors to angiotensin I-converting enzyme
    • Seppo L, Jauhiainen T, Poussa T, Korpela R. 2003. Antihypertensive effect of sour milk and peptides isolated from it that are inhibitors to angiotensin I-converting enzyme. Am. J. Clin. Nutr. 77: 326-330.
    • (2003) Am. J. Clin. Nutr , vol.77 , pp. 326-330
    • Seppo, L.1    Jauhiainen, T.2    Poussa, T.3    Korpela, R.4
  • 36
    • 84897511648 scopus 로고    scopus 로고
    • Anti-infective activities of Lactobacillus strains in the human intestinal microbiota: From probiotics to gastrointestinal anti-infectious biotherapeutic agents
    • Lievin-Le Moal V, Servin AL. 2014. Anti-infective activities of Lactobacillus strains in the human intestinal microbiota: from probiotics to gastrointestinal anti-infectious biotherapeutic agents. Clin. Microbiol. Rev. 27: 167-199.
    • (2014) Clin. Microbiol. Rev , vol.27 , pp. 167-199
    • Lievin-Le Moal, V.1    Servin, A.L.2
  • 37
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2−ΔΔCT method
    • Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2−ΔΔCT method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 38
    • 0030202780 scopus 로고    scopus 로고
    • Identification of an antihypertensive peptide from casein hydrolysate produced by a proteinase from Lactobacillus helveticus CP790
    • Maeno M, Yamamoto N, Takano T. 1996. Identification of an antihypertensive peptide from casein hydrolysate produced by a proteinase from Lactobacillus helveticus CP790. J. Dairy Sci. 79: 1316-1321.
    • (1996) J. Dairy Sci , vol.79 , pp. 1316-1321
    • Maeno, M.1    Yamamoto, N.2    Takano, T.3
  • 39
    • 0029319296 scopus 로고
    • Antihypertensive effect of sour milk and peptides isolated from it that are inhibitors to angiotensin I-converting enzyme
    • Nakamura Y, Yamamoto N, Sakai K, Takano T. 1995. Antihypertensive effect of sour milk and peptides isolated from it that are inhibitors to angiotensin I-converting enzyme. J. Dairy Sci. 78: 1253-1257.
    • (1995) J. Dairy Sci , vol.78 , pp. 1253-1257
    • Nakamura, Y.1    Yamamoto, N.2    Sakai, K.3    Takano, T.4
  • 40
    • 34548864382 scopus 로고    scopus 로고
    • A novel agar medium to detect hydrogen peroxideproducing bacteria based on the Prussian blue-forming reaction
    • Saito M, Seki M, Iida K-I, Nakayama H, Yoshida S-I. 2007. A novel agar medium to detect hydrogen peroxideproducing bacteria based on the Prussian blue-forming reaction. Microbiol. Immunol. 51: 889-892.
    • (2007) Microbiol. Immunol , vol.51 , pp. 889-892
    • Saito, M.1    Seki, M.2    Iida, K.-I.3    Nakayama, H.4    Yoshida, S.-I.5
  • 41
    • 0037307257 scopus 로고    scopus 로고
    • A fermented milk high in bioactive peptides has a blood pressure-lowering effect in hypertensive subjects
    • Seppo L, Jauhiainen T, Poussa T, Korpela R. 2003. A fermented milk high in bioactive peptides has a blood pressure-lowering effect in hypertensive subjects. Am. J. Clin. Nutr. 77: 326-330.
    • (2003) Am. J. Clin. Nutr , vol.77 , pp. 326-330
    • Seppo, L.1    Jauhiainen, T.2    Poussa, T.3    Korpela, R.4
  • 42
    • 77954860410 scopus 로고    scopus 로고
    • Fermented milk of Lactobacillus helveticus IDCC3801 reduces beta-amyloid and attenuates memory deficit
    • Yeon SW, You YS, Kwon HS, Yang EH, Ryu JS, Kang BH, Kang J-H. 2010. Fermented milk of Lactobacillus helveticus IDCC3801 reduces beta-amyloid and attenuates memory deficit. J. Funct. Foods 2: 143-152.
    • (2010) J. Funct. Foods , vol.2 , pp. 143-152
    • Yeon, S.W.1    You, Y.S.2    Kwon, H.S.3    Yang, E.H.4    Ryu, J.S.5    Kang, B.H.6    Kang, J.-H.7
  • 44
    • 77953778874 scopus 로고    scopus 로고
    • Lactobacillus plantarum strain no. 14 reduces adipocyte size in mice fed high-fat diet
    • Takemura N, Okubo T, Sonoyama K. 2010. Lactobacillus plantarum strain no. 14 reduces adipocyte size in mice fed high-fat diet. Exp. Biol. Med. 235: 849-856.
    • (2010) Exp. Biol. Med , vol.235 , pp. 849-856
    • Takemura, N.1    Okubo, T.2    Sonoyama, K.3
  • 45
    • 0033251402 scopus 로고    scopus 로고
    • Screening of lactic acid bacteria for bile salt hydrolase activity
    • Tanaka H, Doesburg K, Iwasaki T, Mierau I. 1999. Screening of lactic acid bacteria for bile salt hydrolase activity. J. Dairy Sci. 82: 2530-2535.
    • (1999) J. Dairy Sci , vol.82 , pp. 2530-2535
    • Tanaka, H.1    Doesburg, K.2    Iwasaki, T.3    Mierau, I.4
  • 46
    • 50949124489 scopus 로고    scopus 로고
    • High-fat diet-induced obesity is attenuated by probiotic strain Lactobacillus paracasei ST11 (NCC2461) in rats
    • Tanida M, Shen J, Maeda K, Horii Y, Yamano T, Fukushima Y, Nagai K. 2008. High-fat diet-induced obesity is attenuated by probiotic strain Lactobacillus paracasei ST11 (NCC2461) in rats. Obes. Res. Clin. Pract. 2: I-II.
    • (2008) Obes. Res. Clin. Pract , vol.2 , pp. I-II
    • Tanida, M.1    Shen, J.2    Maeda, K.3    Horii, Y.4    Yamano, T.5    Fukushima, Y.6    Nagai, K.7
  • 47
    • 84874750499 scopus 로고    scopus 로고
    • Health-promoting properties of Lactobacillus helveticus
    • Taverniti V, Guglielmetti S. 2012. Health-promoting properties of Lactobacillus helveticus. Front. Microbiol. 3: 392.
    • (2012) Front. Microbiol , vol.3 , pp. 392
    • Taverniti, V.1    Guglielmetti, S.2
  • 48
    • 0031769934 scopus 로고    scopus 로고
    • Dietary inulin lowers plasma cholesterol and triacylglycerol and alters biliary bile acid profile in hamsters
    • Trautwein EA, Rieckhoff D, Erbersdobler HF. 1998. Dietary inulin lowers plasma cholesterol and triacylglycerol and alters biliary bile acid profile in hamsters. J. Nutr. 128: 1937-1943.
    • (1998) J. Nutr , vol.128 , pp. 1937-1943
    • Trautwein, E.A.1    Rieckhoff, D.2    Erbersdobler, H.F.3
  • 49
    • 84879284753 scopus 로고    scopus 로고
    • Aggregation and adhesion properties of 22 Lactobacillus strains
    • Tuo Y, Yu H, Ai L, Wu Z, Guo B, Chen W. 2013. Aggregation and adhesion properties of 22 Lactobacillus strains. J. Dairy Sci. 96: 4252-4257.
    • (2013) J. Dairy Sci , vol.96 , pp. 4252-4257
    • Tuo, Y.1    Yu, H.2    Ai, L.3    Wu, Z.4    Guo, B.5    Chen, W.6
  • 50
    • 84893739955 scopus 로고    scopus 로고
    • Hypolipidemic activity of Okra is mediated through inhibition of lipogenesis and upregulation of cholesterol degradation
    • Wang H, Chen G, Ren D, Yang S-T. 2014. Hypolipidemic activity of Okra is mediated through inhibition of lipogenesis and upregulation of cholesterol degradation. Phytother. Res. 28: 268-273.
    • (2014) Phytother. Res , vol.28 , pp. 268-273
    • Wang, H.1    Chen, G.2    Ren, D.3    Yang, S.-T.4
  • 51
    • 39449086721 scopus 로고    scopus 로고
    • Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances
    • Wiegand I, Hilpert K, Hancock RE. 2008. Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances. Nat. Protoc. 3: 163-175.
    • (2008) Nat. Protoc , vol.3 , pp. 163-175
    • Wiegand, I.1    Hilpert, K.2    Hancock, R.E.3
  • 52
    • 0028414339 scopus 로고
    • Antihypertensive effect of the peptides derived from casein by an extracellular proteinase from Lactobacillus helveticus CP790
    • Yamamoto N, Akino A, Takano T. 1994. Antihypertensive effect of the peptides derived from casein by an extracellular proteinase from Lactobacillus helveticus CP790. J. Dairy Sci. 77: 917-922.
    • (1994) J. Dairy Sci , vol.77 , pp. 917-922
    • Yamamoto, N.1    Akino, A.2    Takano, T.3
  • 53
    • 85008124093 scopus 로고    scopus 로고
    • Antihypertensive effects of different kinds of fermented milk in spontaneously hypertensive rats
    • Yamamoto N, Akino A, Takano T. 2014. Antihypertensive effects of different kinds of fermented milk in spontaneously hypertensive rats. Biosci. Biotechnol. Biochem. 58: 776-778.
    • (2014) Biosci. Biotechnol. Biochem , vol.58 , pp. 776-778
    • Yamamoto, N.1    Akino, A.2    Takano, T.3
  • 54
    • 0033161658 scopus 로고    scopus 로고
    • Purification and characterization of an antihypertensive peptide from a yogurt-like product fermented by Lactobacillus helveticus CPN4
    • Yamamoto N, Maeno M, Takano T. 1999. Purification and characterization of an antihypertensive peptide from a yogurt-like product fermented by Lactobacillus helveticus CPN4. J. Dairy Sci. 82: 1388-1393.
    • (1999) J. Dairy Sci , vol.82 , pp. 1388-1393
    • Yamamoto, N.1    Maeno, M.2    Takano, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.