Single cell lineage tracing reveals a role for TgfβR2 in intestinal stem cell dynamics and differentiation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 43, 2016, Pages 12192-12197

  Fischer, Jared M ^a   Calabrese, Peter P ^b   Miller, Ashleigh J ^a   Munoz, Nina M ^c   Grady, William M ^d,e   Shibata, Darryl ^f   Liskay, R Michael ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c UNIVERSITY OF TEXAS   (United States)

^d USA   (United States)

^e UNIVERSITY OF WASHINGTON   (United States)

^f UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Intestinal stem cell; Lgr5; Paneth cell; Tgf ; Tgf R2

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; PROTEIN SERINE THREONINE KINASE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR-BETA TYPE II RECEPTOR;

ANIMAL CELL; CELL CLONE; CELL CLONING; CELL DIFFERENTIATION; CELL EXPANSION; CELL LINEAGE; CELL PROLIFERATION; CELL REGENERATION; CONFERENCE PAPER; CONTROLLED STUDY; GENE MUTATION; HUMAN; HUMAN CELL; IN VIVO STUDY; INTESTINAL STEM CELL; MOUSE; NONHUMAN; PANETH CELL; PRIORITY JOURNAL; SECRETORY CELL; ANIMAL; CELL TRACKING; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; INTESTINE; METABOLISM; MUTATION; PROCEDURES; SIGNAL TRANSDUCTION; SINGLE CELL ANALYSIS; STEM CELL; STEM CELL NICHE;

ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; CELL TRACKING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; INTESTINES; MICE; MUTATION; PANETH CELLS; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; SINGLE-CELL ANALYSIS; STEM CELL NICHE; STEM CELLS;

EID: 84992428159     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1611980113     Document Type: Article

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