Tractable Cre-lox system for stochastic alteration of genes in mice

Nature Methods

Volumn 5, Issue 3, 2008, Pages 227-229

  Miller, Ashleigh J ^a   Dudley, Sandra D ^a   Tsao, Jen Lan ^b   Shibata, Darryl ^b   Liskay, R Michael ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; CRE RECOMBINASE; DNA; K RAS PROTEIN; MISMATCH REPAIR PROTEIN PMS2;

AGING; ALLELE; ARTICLE; CARCINOGENESIS; CELL DIVISION; CELL LINEAGE; DISEASE MODEL; ENZYME ACTIVATION; GENE EXPRESSION; GENE LOCUS; GENE MUTATION; GENETIC RECOMBINATION; INTESTINE CANCER; LOXP SITE; MISMATCH REPAIR; MOUSE; NONHUMAN; ONCOGENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; STEM CELL; WILD TYPE;

ADENOSINE TRIPHOSPHATASES; AGING; ANIMALS; BETA-GALACTOSIDASE; DISEASE MODELS, ANIMAL; DNA MISMATCH REPAIR; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; FRAMESHIFT MUTATION; GENES, RAS; INTEGRASES; INTESTINES; MICE; NEOPLASMS; RECOMBINATION, GENETIC;

MUS;

EID: 40149101401     PISSN: 15487091     EISSN: 15491676     Source Type: Journal    
DOI: 10.1038/nmeth.1183     Document Type: Article

References (14)

1. Jonkers, J. & Berns, A. Nat. Rev. Cancer 2, 251-265 (2002).
2. Johnson, L. et al. Nature 410, 1111-1116 (2001).
3. Wang, W., Warren, M. & Bradley, A. Proc. Natl. Acad. Sci. USA 104, 4501-4505 (2007).
4. Lewandoski, M. & Martin, G.R. Nat. Genet. 17, 223-225 (1997).
5. Baker, S.M. et al. Cell 82, 309-319 (1995).
6. Narayanan, L. et al. Proc. Natl. Acad. Sci. USA 94, 3122-3127 (1997).
7. Harfe, B.D. & Jinks-Robertson, S. Annu. Rev. Genet. 34, 359-399 (2000).
8. Soriano, P. Nat. Genet. 21, 70-71 (1999).
9. Wong, M.H., Hermiston, M.L., Syder, A.J. & Gordon, J.I. Proc. Natl. Acad. Sci. USA 93, 9588-9593 (1996).
10. Marshman, E., Booth, C. & Potten, C.S. Bioessays 24, 91-98 (2002).
11. Jackson, E.L. et al. Genes Dev. 15, 3243-3248 (2001).
12. Calabrese, P., Tavare, S. & Shibata, D. Am. J. Pathol. 164, 1337-1346 (2004).
13. McDonald, S.A. et al. Cell Cycle 5, 808-811 (2006).
14. Robine, S. et al. Proc. Natl. Acad. Sci. USA 82, 8488-8492 (1985).