TGF-β Targets the Hippo Pathway Scaffold RASSF1A to Facilitate YAP/SMAD2 Nuclear Translocation

Molecular Cell

Volumn 63, Issue 1, 2016, Pages 156-166

  Pefani, Dafni Eleftheria ^a   Pankova, Daniela ^a   Abraham, Aswin G ^a   Grawenda, Anna M ^a   Vlahov, Nikola ^a   Scrace, Simon ^a   O’ Neill, Eric ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; CONNECTIVE TISSUE GROWTH FACTOR; MOLECULAR SCAFFOLD; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSCRIPTION FACTOR YAP1; TRANSFORMING GROWTH FACTOR BETA; HIPPO PROTEIN, HUMAN; ITCH PROTEIN, HUMAN; PHOSPHOPROTEIN; PROTEIN SERINE THREONINE KINASE; RASSF1 PROTEIN, HUMAN; REPRESSOR PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SMAD2 PROTEIN, HUMAN; TGF-BETA TYPE I RECEPTOR; TGFB1 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE; YAP1 (YES-ASSOCIATED) PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; BREAST CANCER; CONTROLLED STUDY; EMBRYO; EPITHELIAL MESENCHYMAL TRANSITION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE SILENCING; GENE TRANSLOCATION; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; MALIGNANT NEOPLASTIC DISEASE; MOUSE; NON SMALL CELL LUNG CANCER; NONHUMAN; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN METHYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; TUMOR INVASION; UBIQUITINATION; BREAST TUMOR; CELL MEMBRANE; CELL MOTION; DNA METHYLATION; FEMALE; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; LUNG TUMOR; METABOLISM; NUCLEOCYTOPLASMIC TRANSPORT; PATHOLOGY; RNA INTERFERENCE; TUMOR CELL LINE;

ACTIVE TRANSPORT, CELL NUCLEUS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MEMBRANE; CELL MOVEMENT; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; NEOPLASM INVASIVENESS; PHOSPHOPROTEINS; PROTEIN-SERINE-THREONINE KINASES; PROTEOLYSIS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; REPRESSOR PROTEINS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; TRANSCRIPTION, GENETIC; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA1; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES;

EID: 84992401703     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2016.05.012     Document Type: Article

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