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Volumn 4, Issue 3, 2013, Pages

The E3 ubiquitin ligase itch regulates tumor suppressor protein RASSF5/NORE1 stability in an acetylation-dependent manner

Author keywords

Acetylation; Cell Cycle; Itch; RASSF5; Ubiquitination

Indexed keywords

PROTEASOME; PROTEIN; RASSF5 PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; ITCH PROTEIN, HUMAN; MONOMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN BINDING; RASSF5 PROTEIN, HUMAN; REPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE;

EID: 84875878283     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.91     Document Type: Article
Times cited : (42)

References (38)
  • 1
    • 77952393767 scopus 로고    scopus 로고
    • Growth and tumor suppressor nore1a is a regulatory node between ras signaling and microtubule nucleation
    • Bee C, Moshnikova A, Mellor CD, Molloy JE, Koryakina Y, Stieglitz B et al. Growth and tumor suppressor NORE1A is a regulatory node between Ras signaling and microtubule nucleation. J Biol Chem 2010; 285: 16258-16266.
    • (2010) J Biol Chem , vol.285 , pp. 16258-16266
    • Bee, C.1    Moshnikova, A.2    Mellor, C.D.3    Molloy, J.E.4    Koryakina, Y.5    Stieglitz, B.6
  • 3
    • 77249167127 scopus 로고    scopus 로고
    • Functional interaction of the ras effector rassf5 with the tyrosine kinase lck: Critical role in nucleocytoplasmic transport and cell cycle regulation
    • Kumari G, Singhal PK, Suryaraja R, Mahalingam S. Functional interaction of the Ras effector RASSF5 with the tyrosine kinase Lck: critical role in nucleocytoplasmic transport and cell cycle regulation. J Mol Biol 2010; 397: 89-109.
    • (2010) J Mol Biol , vol.397 , pp. 89-109
    • Kumari, G.1    Singhal, P.K.2    Suryaraja, R.3    Mahalingam, S.4
  • 4
    • 78049359250 scopus 로고    scopus 로고
    • Tumor suppressor ras association domain family 5 (rassf5/nore1) mediates death receptor ligand-induced apoptosis
    • Park J, Kang SI, Lee SY, Zhang XF, Kim MS, Beers LF et al. Tumor suppressor ras association domain family 5 (RASSF5/NORE1) mediates death receptor ligand-induced apoptosis. J Biol Chem 2010; 285: 35029-35038.
    • (2010) J Biol Chem , vol.285 , pp. 35029-35038
    • Park, J.1    Kang, S.I.2    Lee, S.Y.3    Zhang, X.F.4    Kim, M.S.5    Beers, L.F.6
  • 5
    • 0032489384 scopus 로고    scopus 로고
    • Identification of nore1 as a potential ras effector
    • Vavvas D, Li X, Avruch J, Zhang XF. Identification of Nore1 as a potential Ras effector. J Biol Chem 1998; 273: 5439-5442.
    • (1998) J Biol Chem , vol.273 , pp. 5439-5442
    • Vavvas, D.1    Li, X.2    Avruch, J.3    Zhang, X.F.4
  • 6
    • 33847206401 scopus 로고    scopus 로고
    • The salvador-warts-hippo pathway - An emerging tumour-suppressor network
    • Harvey K, Tapon N. The Salvador-Warts-hippo pathway - An emerging tumour-suppressor network. Nat Rev Cancer 2007; 7: 182-191.
    • (2007) Nat Rev Cancer , vol.7 , pp. 182-191
    • Harvey, K.1    Tapon, N.2
  • 7
    • 34547162995 scopus 로고    scopus 로고
    • Structural insight into dimeric interaction of the sarah domains from mst1 and rassf family proteins in the apoptosis pathway
    • Hwang E, Ryu KS, Paakkonen K, Guntert P, Cheong HK, Lim DS et al. Structural insight into dimeric interaction of the SARAH domains from Mst1 and RASSF family proteins in the apoptosis pathway. Proc Natl Acad Sci USA 2007; 104: 9236-9241.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 9236-9241
    • Hwang, E.1    Ryu, K.S.2    Paakkonen, K.3    Guntert, P.4    Cheong, H.K.5    Lim, D.S.6
  • 8
    • 39849097306 scopus 로고    scopus 로고
    • The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals
    • Zeng Q, Hong W. The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals. Cancer Cell 2008; 13: 188-192.
    • (2008) Cancer Cell , vol.13 , pp. 188-192
    • Zeng, Q.1    Hong, W.2
  • 9
    • 84862224603 scopus 로고    scopus 로고
    • The rassf gene family members rassf5, rassf6 and rassf7 show frequent dna methylation in neuroblastoma
    • Djos A, Martinsson T, Kogner P, Caren H. The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma. Mol Cancer 2012; 11: 40.
    • (2012) Mol Cancer , vol.11 , pp. 40
    • Djos, A.1    Martinsson, T.2    Kogner, P.3    Caren, H.4
  • 10
    • 44949095267 scopus 로고    scopus 로고
    • Assessment of nore1a as a putative tumor suppressor in human neuroblastoma
    • Geli J, Kogner P, Lanner F, Natalishvili N, Juhlin C, Kiss N et al. Assessment of NORE1A as a putative tumor suppressor in human neuroblastoma. Int J Cancer 2008; 123: 389-394.
    • (2008) Int J Cancer , vol.123 , pp. 389-394
    • Geli, J.1    Kogner, P.2    Lanner, F.3    Natalishvili, N.4    Juhlin, C.5    Kiss, N.6
  • 11
    • 33947099350 scopus 로고    scopus 로고
    • Nuclear transport of ras-associated tumor suppressor proteins: Different transport receptor binding specificities for arginine-rich nuclear targeting signals
    • Kumari G, Singhal PK, Rao MR, Mahalingam S. Nuclear transport of Ras-associated tumor suppressor proteins: different transport receptor binding specificities for arginine-rich nuclear targeting signals. J Mol Biol 2007; 367: 294-1311.
    • (2007) J Mol Biol , vol.367 , pp. 294-1311
    • Kumari, G.1    Singhal, P.K.2    Rao, M.R.3    Mahalingam, S.4
  • 12
    • 0030910308 scopus 로고    scopus 로고
    • Fbp ww domains and the abl sh3 domain bind to a specific class of proline-rich ligands
    • Bedford MT, Chan DC, Leder P. FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands. EMBO J 1997; 16: 2376-2383.
    • (1997) EMBO J , vol.16 , pp. 2376-2383
    • Bedford, M.T.1    Chan, D.C.2    Leder, P.3
  • 13
    • 0036157980 scopus 로고    scopus 로고
    • The ww domain: Linking cell signalling to the membrane cytoskeleton
    • Ilsley JL, Sudol M, Winder SJ. The WW domain: linking cell signalling to the membrane cytoskeleton. Cell Signal 2002; 14: 183-189.
    • (2002) Cell Signal , vol.14 , pp. 183-189
    • Ilsley, J.L.1    Sudol, M.2    Winder, S.J.3
  • 14
    • 0037138411 scopus 로고    scopus 로고
    • Ww and sh3 domains, two different scaffolds to recognize proline-rich ligands
    • Macias MJ, Wiesner S, Sudol M. WW and SH3 domains, two different scaffolds to recognize proline-rich ligands. FEBS Lett 2002; 513: 30-37.
    • (2002) FEBS Lett , vol.513 , pp. 30-37
    • Macias, M.J.1    Wiesner, S.2    Sudol, M.3
  • 15
    • 41949138130 scopus 로고    scopus 로고
    • Tumor suppressor lats1 is a negative regulator of oncogene yap
    • Hao Y, Chun A, Cheung K, Rashidi B, Yang X. Tumor suppressor LATS1 is a negative regulator of oncogene YAP. J Biol Chem 2008; 283: 5496-5509.
    • (2008) J Biol Chem , vol.283 , pp. 5496-5509
    • Hao, Y.1    Chun, A.2    Cheung, K.3    Rashidi, B.4    Yang, X.5
  • 17
    • 79952266588 scopus 로고    scopus 로고
    • Negative regulation of the hippo pathway by e3 ubiquitin ligase itch is sufficient to promote tumorigenicity
    • Salah Z, Melino G, Aqeilan RI. Negative regulation of the hippo pathway by E3 ubiquitin ligase ITCH is sufficient to promote tumorigenicity. Cancer Res 2011; 71: 2010-2020.
    • (2011) Cancer Res , vol.71 , pp. 2010-2020
    • Salah, Z.1    Melino, G.2    Aqeilan, R.I.3
  • 18
    • 79959962948 scopus 로고    scopus 로고
    • Newcomers to the ww domain-mediated network of the hippo tumor suppressor pathway
    • Sudol M. Newcomers to the WW domain-mediated network of the hippo tumor suppressor pathway. Genes Cancer 2011; 1: 1115-1118.
    • (2011) Genes Cancer , vol.1 , pp. 1115-1118
    • Sudol, M.1
  • 19
    • 35948961118 scopus 로고    scopus 로고
    • Inactivation of yap oncoprotein by the hippo pathway is involved in cell contact inhibition and tissue growth control
    • Zhao B, Wei X, Li W, Udan RS, Yang Q, Kim J et al. Inactivation of YAP oncoprotein by the hippo pathway is involved in cell contact inhibition and tissue growth control. Genes Dev 2007; 21: 2747-2761.
    • (2007) Genes Dev , vol.21 , pp. 2747-2761
    • Zhao, B.1    Wei, X.2    Li, W.3    Udan, R.S.4    Yang, Q.5    Kim, J.6
  • 20
    • 55549085229 scopus 로고    scopus 로고
    • A regulatory circuit controlling itch-mediated p73 degradation by runx
    • Levy D, Reuven N, Shaul Y. A regulatory circuit controlling Itch-mediated p73 degradation by Runx. J Biol Chem 2008; 283: 27462-27468.
    • (2008) J Biol Chem , vol.283 , pp. 27462-27468
    • Levy, D.1    Reuven, N.2    Shaul, Y.3
  • 21
    • 15444367709 scopus 로고    scopus 로고
    • The ubiquitin-protein ligase itch regulates p73 stability
    • Rossi M, De Laurenzi V, Munarriz E, Green DR, Liu YC et al. The ubiquitin-protein ligase Itch regulates p73 stability. EMBO 2005; 24: 836-848.
    • (2005) EMBO , vol.24 , pp. 836-848
    • Rossi, M.1    De Laurenzi, V.2    Munarriz, E.3    Green, D.R.4    Liu, Y.C.5
  • 22
    • 2442708891 scopus 로고    scopus 로고
    • Nore1 inhibits tumor cell growth independent of ras or the mst1/2 kinases
    • Aoyama Y, Avruch J, Zhang XF. Nore1 inhibits tumor cell growth independent of Ras or the MST1/2 kinases. Oncogene 2004; 23: 3426-3433.
    • (2004) Oncogene , vol.23 , pp. 3426-3433
    • Aoyama, Y.1    Avruch, J.2    Zhang, X.F.3
  • 23
    • 5044225158 scopus 로고    scopus 로고
    • Jun turnover is controlled through jnk-dependent phosphorylation of the e3 ligase itch
    • Gao M, Labuda T, Xia Y, Gallagher E, Fang D, Liu YC et al. Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase Itch. Science 2004; 306: 271-275.
    • (2004) Science , vol.306 , pp. 271-275
    • Gao, M.1    Labuda, T.2    Xia, Y.3    Gallagher, E.4    Fang, D.5    Liu, Y.C.6
  • 25
    • 55549098921 scopus 로고    scopus 로고
    • Mst2 and lats kinases regulate apoptotic function of yes kinase-associated protein (yap)
    • Oka T, Mazack V, Sudol M. Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP). J Biol Chem 2008; 283: 27534-27546.
    • (2008) J Biol Chem , vol.283 , pp. 27534-27546
    • Oka, T.1    Mazack, V.2    Sudol, M.3
  • 26
    • 56049090769 scopus 로고    scopus 로고
    • Acetylation of non-histone proteins modulates cellular signalling at multiple levels
    • Spangea S, Wagner T, Heinzel T, Kramer OH. Acetylation of non-histone proteins modulates cellular signalling at multiple levels. Int J Biochem Cell Biol 2009; 41: 185-198.
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 185-198
    • Spangea, S.1    Wagner, T.2    Heinzel, T.3    Kramer, O.H.4
  • 27
    • 84858795617 scopus 로고    scopus 로고
    • Deacetylation of foxo3 by sirt1 or sirt2 leads to skp2-mediated foxo3 ubiquitination and degradation
    • Wang F, Chan CH, Chen K, Guan X, Lin HK, Tong Q. Deacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradation. Oncogene 2012; 31: 1546-1557.
    • (2012) Oncogene , vol.31 , pp. 1546-1557
    • Wang, F.1    Chan, C.H.2    Chen, K.3    Guan, X.4    Lin, H.K.5    Tong, Q.6
  • 28
    • 29544433771 scopus 로고    scopus 로고
    • Negative regulation of the e3 ubiquitin ligase itch via fyn-mediated tyrosine phosphorylation
    • Yang C, Zhou W, Jeon MS, Demydenko D, Harada Y, Zhou H et al. Negative regulation of the E3 ubiquitin ligase itch via Fyn-mediated tyrosine phosphorylation. Mol Cell 2006; 21: 135-141.
    • (2006) Mol Cell , vol.21 , pp. 135-141
    • Yang, C.1    Zhou, W.2    Jeon, M.S.3    Demydenko, D.4    Harada, Y.5    Zhou, H.6
  • 29
    • 36048958965 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: Overview and perspectives
    • Dokmanovic M, Clarke C, Marks PA. Histone deacetylase inhibitors: overview and perspectives. Mol Cancer Res 2007; 5: 981-989.
    • (2007) Mol Cancer Res , vol.5 , pp. 981-989
    • Dokmanovic, M.1    Clarke, C.2    Marks, P.A.3
  • 30
    • 39149109887 scopus 로고    scopus 로고
    • The structural basis of protein acetylation by the p300/cbp transcriptional coactivator
    • Liu X,Wang L, Zhao K, Thompson PR, Hwang Y, Marmorstein R et al. The structural basis of protein acetylation by the p300/CBP transcriptional coactivator. Nature 2008; 451: 846-850.
    • (2008) Nature , vol.451 , pp. 846-850
    • Liu, X.1    Wang, L.2    Zhao, K.3    Thompson, P.R.4    Hwang, Y.5    Marmorstein, R.6
  • 31
    • 77958494807 scopus 로고    scopus 로고
    • Lats tumor suppressor: A new governor of cellular homeostasis
    • Visser S, Yang X. LATS tumor suppressor: a new governor of cellular homeostasis. Cell Cycle 2010; 9: 3892-3903.
    • (2010) Cell Cycle , vol.9 , pp. 3892-3903
    • Visser, S.1    Yang, X.2
  • 32
    • 0028929414 scopus 로고
    • Identifying tumor suppressors in genetic mosaics: The drosophila lats gene encodes a putative protein kinase
    • Xu T, Wang W, Zhang S, Stewart RA, Yu W. Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase. Development 1995; 121: 1053-1063.
    • (1995) Development , vol.121 , pp. 1053-1063
    • Xu, T.1    Wang, W.2    Zhang, S.3    Stewart, R.A.4    Yu, W.5
  • 33
    • 45849153870 scopus 로고    scopus 로고
    • The hect family of e3 ubiquitin ligases: Multiple players in cancer development
    • Bernassola F, Karin M, Ciechanover A, Melino G. The HECT family of E3 ubiquitin ligases: multiple players in cancer development. Cancer Cell 2008; 14: 10-21.
    • (2008) Cancer Cell , vol.14 , pp. 10-21
    • Bernassola, F.1    Karin, M.2    Ciechanover, A.3    Melino, G.4
  • 34
    • 79960027086 scopus 로고    scopus 로고
    • Ww domain interactions regulate the hippo tumor suppressor pathway
    • Salah Z, Aqeilan RI. WW domain interactions regulate the hippo tumor suppressor pathway. Cell Death Dis 2011; 2: e172.
    • (2011) Cell Death Dis , vol.2
    • Salah, Z.1    Aqeilan, R.I.2
  • 35
    • 84862822518 scopus 로고    scopus 로고
    • High expression of the transcriptional co-activator p300 predicts poor survival in resectable non-small cell lung cancers
    • Hou X, Li Y, Luo RZ, Fu JH, He JH, Zhang LJ et al. High expression of the transcriptional co-activator p300 predicts poor survival in resectable non-small cell lung cancers. Eur J Surg Oncol 2012; 38: 523-530.
    • (2012) Eur J Surg Oncol , vol.38 , pp. 523-530
    • Hou, X.1    Li, Y.2    Luo, R.Z.3    Fu, J.H.4    He, J.H.5    Zhang, L.J.6
  • 36
    • 84861539820 scopus 로고    scopus 로고
    • High expression of p300 is linked to aggressive features and poor prognosis of nasopharyngeal carcinoma
    • Liao ZW, Zhou TC, Tan XJ, Song XL, Liu Y, Shi XY et al. High expression of p300 is linked to aggressive features and poor prognosis of nasopharyngeal carcinoma. J Transl Med 2012; 10: 110.
    • (2012) J Transl Med , vol.10 , pp. 110
    • Liao, Z.W.1    Zhou, T.C.2    Tan, X.J.3    Song, X.L.4    Liu, Y.5    Shi, X.Y.6
  • 37
    • 0033756590 scopus 로고    scopus 로고
    • Latent membrane protein 2a of epstein-barr virus binds ww domain e3 protein-ubiquitin ligases that ubiquitinate b-cell tyrosine kinases
    • Winberg G, Matskova L, Chen F, Plant P, Rotin D, Gish G et al. Latent membrane protein 2A of Epstein-Barr virus binds WW domain E3 protein-ubiquitin ligases that ubiquitinate B-cell tyrosine kinases. Mol Cell Biol 2000; 20: 8526-8535.
    • (2000) Mol Cell Biol , vol.20 , pp. 8526-8535
    • Winberg, G.1    Matskova, L.2    Chen, F.3    Plant, P.4    Rotin, D.5    Gish, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.