메뉴 건너뛰기




Volumn 72, Issue 15, 2012, Pages 3817-3827

Loss of Rassf1a synergizes with deregulated Runx2 signaling in tumorigenesis

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR 3; MESSENGER RNA; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR YAP1;

EID: 84864829046     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-11-3343     Document Type: Article
Times cited : (42)

References (45)
  • 1
    • 34548220076 scopus 로고    scopus 로고
    • The Ras-association domain family (RASSF) members and their role in human tumourigenesis
    • van der Weyden L, Adams DJ. The Ras-association domain family (RASSF) members and their role in human tumourigenesis. Biochim Biophys Acta 2007;1776:58-85.
    • (2007) Biochim Biophys Acta , vol.1776 , pp. 58-85
    • Van Der Weyden, L.1    Adams, D.J.2
  • 3
    • 77957883342 scopus 로고    scopus 로고
    • The Hippo signaling pathway in development and cancer
    • Pan D. The Hippo signaling pathway in development and cancer. Developmental Cell 2010;19:491-505.
    • (2010) Developmental Cell , vol.19 , pp. 491-505
    • Pan, D.1
  • 4
    • 0042232429 scopus 로고    scopus 로고
    • Hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts
    • Wu S, Huang J, Dong J, Pan D. Hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts. Cell 2003;114:445-56.
    • (2003) Cell , vol.114 , pp. 445-456
    • Wu, S.1    Huang, J.2    Dong, J.3    Pan, D.4
  • 5
    • 34247182696 scopus 로고    scopus 로고
    • Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila
    • Wei X, Shimizu T, Lai ZC. Mob as tumor suppressor is activated by Hippo kinase for growth inhibition in Drosophila. EMBO J 2007;26:1772-81.
    • (2007) EMBO J , vol.26 , pp. 1772-1781
    • Wei, X.1    Shimizu, T.2    Lai, Z.C.3
  • 6
    • 23744458034 scopus 로고    scopus 로고
    • The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP
    • Huang J, Wu S, Barrera J, Matthews K, Pan D. The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP. Cell 2005;122:421-34.
    • (2005) Cell , vol.122 , pp. 421-434
    • Huang, J.1    Wu, S.2    Barrera, J.3    Matthews, K.4    Pan, D.5
  • 7
    • 42049103717 scopus 로고    scopus 로고
    • Yorkie and Scalloped: Partners in growth activation
    • Bandura JL, Edgar BA. Yorkie and Scalloped: partners in growth activation. Dev Cell 2008;14:315-6.
    • (2008) Dev Cell , vol.14 , pp. 315-316
    • Bandura, J.L.1    Edgar, B.A.2
  • 8
    • 47549095853 scopus 로고    scopus 로고
    • TEAD mediates YAPdependent gene induction and growth control
    • Zhao B, Ye X, Yu J, Li L, Li W, Li S, et al. TEAD mediates YAPdependent gene induction and growth control. Genes Dev 2008;22:1962-71.
    • (2008) Genes Dev , vol.22 , pp. 1962-1971
    • Zhao, B.1    Ye, X.2    Yu, J.3    Li, L.4    Li, W.5    Li, S.6
  • 9
    • 0035873391 scopus 로고    scopus 로고
    • TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm
    • Vassilev A, Kaneko KJ, Shu H, Zhao Y, DePamphilis ML. TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm. Genes Dev 2001;15:1229-41.
    • (2001) Genes Dev , vol.15 , pp. 1229-1241
    • Vassilev, A.1    Kaneko, K.J.2    Shu, H.3    Zhao, Y.4    DePamphilis, M.L.5
  • 10
    • 0035805487 scopus 로고    scopus 로고
    • Physical interaction with Yes-associated protein enhances p73 transcriptional activity
    • Strano S, Munarriz E, Rossi M, Castagnoli L, Shaul Y, Sacchi A, et al. Physical interaction with Yes-associated protein enhances p73 transcriptional activity. J Biol Chem 2001;276:15164-73.
    • (2001) J Biol Chem , vol.276 , pp. 15164-15173
    • Strano, S.1    Munarriz, E.2    Rossi, M.3    Castagnoli, L.4    Shaul, Y.5    Sacchi, A.6
  • 11
    • 0042858208 scopus 로고    scopus 로고
    • WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus
    • Komuro A, Nagai M, Navin NE, Sudol M. WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus. J Biol Chem 2003;278:33334-41.
    • (2003) J Biol Chem , vol.278 , pp. 33334-33341
    • Komuro, A.1    Nagai, M.2    Navin, N.E.3    Sudol, M.4
  • 12
    • 0033522472 scopus 로고    scopus 로고
    • A WW domaincontaining yes-associated protein (YAP) is a novel transcriptional co-activator
    • Yagi R, Chen LF, Shigesada K, Murakami Y, Ito Y. A WW domaincontaining yes-associated protein (YAP) is a novel transcriptional co-activator. EMBO J 1999;18:2551-62.
    • (1999) EMBO J , vol.18 , pp. 2551-2562
    • Yagi, R.1    Chen, L.F.2    Shigesada, K.3    Murakami, Y.4    Ito, Y.5
  • 13
    • 34748812613 scopus 로고    scopus 로고
    • RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein
    • Matallanas D, Romano D, Yee K, Meissl K, Kucerova L, Piazzolla D, et al. RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein. Mol Cell 2007;27:962-75.
    • (2007) Mol Cell , vol.27 , pp. 962-975
    • Matallanas, D.1    Romano, D.2    Yee, K.3    Meissl, K.4    Kucerova, L.5    Piazzolla, D.6
  • 14
    • 71649111253 scopus 로고    scopus 로고
    • ATM regulates a RASSF1A-dependent DNA damage response
    • Hamilton G, Yee KS, Scrace S, O'Neill E. ATM regulates a RASSF1A-dependent DNA damage response. Curr Biol 2009;19:2020-5.
    • (2009) Curr Biol , vol.19 , pp. 2020-2025
    • Hamilton, G.1    Yee, K.S.2    Scrace, S.3    O'Neill, E.4
  • 16
    • 22444444402 scopus 로고    scopus 로고
    • Cancer gene discovery in solid tumours using transposonbased somatic mutagenesis in the mouse
    • Collier LS, Carlson CM, Ravimohan S, Dupuy AJ, Largaespada DA. Cancer gene discovery in solid tumours using transposonbased somatic mutagenesis in the mouse. Nature 2005;436:272-6.
    • (2005) Nature , vol.436 , pp. 272-276
    • Collier, L.S.1    Carlson, C.M.2    Ravimohan, S.3    Dupuy, A.J.4    Largaespada, D.A.5
  • 17
    • 22444431606 scopus 로고    scopus 로고
    • Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system
    • Dupuy AJ, Akagi K, Largaespada DA, Copeland NG, Jenkins NA. Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system. Nature 2005;436:221-6.
    • (2005) Nature , vol.436 , pp. 221-226
    • Dupuy, A.J.1    Akagi, K.2    Largaespada, D.A.3    Copeland, N.G.4    Jenkins, N.A.5
  • 18
    • 82255179056 scopus 로고    scopus 로고
    • Insertional mutagenesis reveals multiple networks of cooperating genes driving intestinal tumorigenesis
    • March HN, Rust AG, Wright NA, ten Hoeve J, de Ridder J, Eldridge M, et al. Insertional mutagenesis reveals multiple networks of cooperating genes driving intestinal tumorigenesis. Nat Genet 2011; 43:1202-9.
    • (2011) Nat Genet , vol.43 , pp. 1202-1209
    • March, H.N.1    Rust, A.G.2    Wright, N.A.3    Ten Hoeve, J.4    De Ridder, J.5    Eldridge, M.6
  • 19
    • 33846025793 scopus 로고    scopus 로고
    • Detecting statistically significant common insertion sites in retroviral insertional mutagenesis screens
    • de Ridder J, Uren A, Kool J, Reinders M, Wessels L. Detecting statistically significant common insertion sites in retroviral insertional mutagenesis screens. PLoS Comput Biol 2006;2:e166.
    • (2006) PLoS Comput Biol , vol.2
    • De Ridder, J.1    Uren, A.2    Kool, J.3    Reinders, M.4    Wessels, L.5
  • 20
    • 77953565272 scopus 로고    scopus 로고
    • YAP1-friend and foe
    • Yee KS, O'Neill E. YAP1-friend and foe. Cell Cycle 2010;9:1447-8.
    • (2010) Cell Cycle , vol.9 , pp. 1447-1448
    • Yee, K.S.1    O'Neill, E.2
  • 21
    • 0024380087 scopus 로고
    • Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells
    • Schreiber E, Matthias P, Muller MM, Schaffner W. Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res 1989;17:6419.
    • (1989) Nucleic Acids Res , vol.17 , pp. 6419
    • Schreiber, E.1    Matthias, P.2    Muller, M.M.3    Schaffner, W.4
  • 22
    • 0001646484 scopus 로고
    • Cox's regression model for counting processes, a large sample study
    • Andersen P, Gill R. Cox's regression model for counting processes, a large sample study. Annal Stat 1982;10:1100-20.
    • (1982) Annal Stat , vol.10 , pp. 1100-1120
    • Andersen, P.1    Gill, R.2
  • 23
    • 0028831959 scopus 로고
    • The rsp5-domain is shared by proteins of diverse functions
    • Hofmann K, Bucher P. The rsp5-domain is shared by proteins of diverse functions. FEBS Lett 1995;358:153-7.
    • (1995) FEBS Lett , vol.358 , pp. 153-157
    • Hofmann, K.1    Bucher, P.2
  • 24
    • 15444351110 scopus 로고    scopus 로고
    • Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia
    • Mundlos S, Otto F, Mundlos C, Mulliken JB, Aylsworth AS, Albright S, et al. Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia. Cell 1997;89:773-9.
    • (1997) Cell , vol.89 , pp. 773-779
    • Mundlos, S.1    Otto, F.2    Mundlos, C.3    Mulliken, J.B.4    Aylsworth, A.S.5    Albright, S.6
  • 25
    • 0030684749 scopus 로고    scopus 로고
    • Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
    • Komori T, Yagi H, Nomura S, Yamaguchi A, Sasaki K, Deguchi K, et al. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 1997;89:755-64.
    • (1997) Cell , vol.89 , pp. 755-764
    • Komori, T.1    Yagi, H.2    Nomura, S.3    Yamaguchi, A.4    Sasaki, K.5    Deguchi, K.6
  • 26
    • 0030666372 scopus 로고    scopus 로고
    • Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development
    • Otto F, Thornell AP, Crompton T, Denzel A, Gilmour KC, Rosewell IR, et al. Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell 1997;89:765-71.
    • (1997) Cell , vol.89 , pp. 765-771
    • Otto, F.1    Thornell, A.P.2    Crompton, T.3    Denzel, A.4    Gilmour, K.C.5    Rosewell, I.R.6
  • 27
    • 67649450275 scopus 로고    scopus 로고
    • High-throughput insertional mutagenesis screens in mice to identify oncogenic networks
    • Kool J, Berns A. High-throughput insertional mutagenesis screens in mice to identify oncogenic networks. Nat Rev Cancer 2009;9:389-99.
    • (2009) Nat Rev Cancer , vol.9 , pp. 389-399
    • Kool, J.1    Berns, A.2
  • 29
    • 0033918563 scopus 로고    scopus 로고
    • Epigenetic inactivation of a RAS association domain family protein from the lung tumor suppressor locus 3p21.3
    • Dammann R, Li C, Yoon JH, Chin PL, Bates S, Pfeifer GP. Epigenetic inactivation of a RAS association domain family protein from the lung tumor suppressor locus 3p21.3. Nat Genet 2000;25:315-9.
    • (2000) Nat Genet , vol.25 , pp. 315-319
    • Dammann, R.1    Li, C.2    Yoon, J.H.3    Chin, P.L.4    Bates, S.5    Pfeifer, G.P.6
  • 30
    • 33749038677 scopus 로고    scopus 로고
    • Multiple endocrine neoplasia type 1 interacts with forkhead transcription factor CHES1 in DNA damage response
    • Busygina V, Kottemann MC, Scott KL, Plon SE, Bale AE. Multiple endocrine neoplasia type 1 interacts with forkhead transcription factor CHES1 in DNA damage response. Cancer Res 2006;66:8397-403.
    • (2006) Cancer Res , vol.66 , pp. 8397-8403
    • Busygina, V.1    Kottemann, M.C.2    Scott, K.L.3    Plon, S.E.4    Bale, A.E.5
  • 31
    • 78751499344 scopus 로고    scopus 로고
    • Down-regulation of Ches1 and other novel genes in oral cancer cells chronically exposed to areca nut extract
    • Chen YJ, Liao CT, Chen PJ, Lee LY, Li YC, Chen IH, et al. Down-regulation of Ches1 and other novel genes in oral cancer cells chronically exposed to areca nut extract. Head Neck 2011;33:257-66.
    • (2011) Head Neck , vol.33 , pp. 257-266
    • Chen, Y.J.1    Liao, C.T.2    Chen, P.J.3    Lee, L.Y.4    Li, Y.C.5    Chen, I.H.6
  • 32
    • 0027538301 scopus 로고
    • Dephosphorylation of cdc25-C by a type-2A protein phosphatase: Specific regulation during the cell cycle in Xenopus egg extracts
    • Clarke PR, Hoffmann I, Draetta G, Karsenti E. Dephosphorylation of cdc25-C by a type-2A protein phosphatase: specific regulation during the cell cycle in Xenopus egg extracts. Mol Biol Cell 1993;4:397-411.
    • (1993) Mol Biol Cell , vol.4 , pp. 397-411
    • Clarke, P.R.1    Hoffmann, I.2    Draetta, G.3    Karsenti, E.4
  • 33
    • 77951154173 scopus 로고    scopus 로고
    • MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors
    • Liu X, Sempere LF, Ouyang H, Memoli VA, Andrew AS, Luo Y, et al. MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors. J Clin Invest 2010;120:1298-309.
    • (2010) J Clin Invest , vol.120 , pp. 1298-1309
    • Liu, X.1    Sempere, L.F.2    Ouyang, H.3    Memoli, V.A.4    Andrew, A.S.5    Luo, Y.6
  • 34
    • 18044393595 scopus 로고    scopus 로고
    • Dissociation of cohesin from chromosome arms and loss of arm cohesion during early mitosis depends on phosphorylation of SA2
    • Hauf S, Roitinger E, Koch B, Dittrich CM, Mechtler K, Peters JM. Dissociation of cohesin from chromosome arms and loss of arm cohesion during early mitosis depends on phosphorylation of SA2. PLoS Biol 2005;3:e69.
    • (2005) PLoS Biol , vol.3
    • Hauf, S.1    Roitinger, E.2    Koch, B.3    Dittrich, C.M.4    Mechtler, K.5    Peters, J.M.6
  • 36
    • 27544441643 scopus 로고    scopus 로고
    • Runx-dependent expression of PKC is critical for cell survival in the sea urchin embryo
    • Dickey-Sims C, Robertson AJ, Rupp DE, McCarthy JJ, Coffman JA. Runx-dependent expression of PKC is critical for cell survival in the sea urchin embryo. BMC Biol 2005;3:18-29.
    • (2005) BMC Biol , vol.3 , pp. 18-29
    • Dickey-Sims, C.1    Robertson, A.J.2    Rupp, D.E.3    McCarthy, J.J.4    Coffman, J.A.5
  • 37
    • 10044283146 scopus 로고    scopus 로고
    • Ras/mitogen-activated protein kinase signaling activates Ets-1 and Ets-2 by CBP/p300 recruitment
    • Foulds CE, Nelson ML, Blaszczak AG, Graves BJ. Ras/mitogen-activated protein kinase signaling activates Ets-1 and Ets-2 by CBP/p300 recruitment. Mol Cell Biol 2004;24:10954-64.
    • (2004) Mol Cell Biol , vol.24 , pp. 10954-10964
    • Foulds, C.E.1    Nelson, M.L.2    Blaszczak, A.G.3    Graves, B.J.4
  • 39
    • 78149483788 scopus 로고    scopus 로고
    • FGFR3, HRAS, KRAS, NRAS and PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy
    • Kompier LC, Lurkin I, van der Aa MN, van Rhijn BW, van der Kwast TH, Zwarthoff EC. FGFR3, HRAS, KRAS, NRAS and PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy. PLoS One 2010;5:e13821.
    • (2010) PLoS One , vol.5
    • Kompier, L.C.1    Lurkin, I.2    Van Der Aa, M.N.3    Van Rhijn, B.W.4    Van Der Kwast, T.H.5    Zwarthoff, E.C.6
  • 40
    • 79955788046 scopus 로고    scopus 로고
    • Somatic mutation of fibroblast growth factor receptor-3 (FGFR3) defines a distinct morphological subtype of high-grade urothelial carcinoma
    • Al-Ahmadie HA, Iyer G, Janakiraman M, Lin O, Heguy A, Tickoo SK, et al. Somatic mutation of fibroblast growth factor receptor-3 (FGFR3) defines a distinct morphological subtype of high-grade urothelial carcinoma. J Pathol 2011;224:270-9.
    • (2011) J Pathol , vol.224 , pp. 270-279
    • Al-Ahmadie, H.A.1    Iyer, G.2    Janakiraman, M.3    Lin, O.4    Heguy, A.5    Tickoo, S.K.6
  • 41
    • 0024081279 scopus 로고
    • Isolation of the Drosophila segmentation gene runt and analysis of its expression during embryogenesis
    • Gergen JP, Butler BA. Isolation of the Drosophila segmentation gene runt and analysis of its expression during embryogenesis. Genes Dev 1988;2:1179-93.
    • (1988) Genes Dev , vol.2 , pp. 1179-1193
    • Gergen, J.P.1    Butler, B.A.2
  • 42
    • 0031836965 scopus 로고    scopus 로고
    • Two domains unique to osteoblast-speci fic transcription factor Osf2/Cbfa1 contribute to its transactivation function and its inability to heterodimerize with Cbfbeta
    • Thirunavukkarasu K, Mahajan M, McLarren KW, Stifani S, Karsenty G. Two domains unique to osteoblast-speci fic transcription factor Osf2/Cbfa1 contribute to its transactivation function and its inability to heterodimerize with Cbfbeta. Mol Cell Biol 1998;18:4197-208.
    • (1998) Mol Cell Biol , vol.18 , pp. 4197-4208
    • Thirunavukkarasu, K.1    Mahajan, M.2    McLarren, K.W.3    Stifani, S.4    Karsenty, G.5
  • 43
    • 18344372018 scopus 로고    scopus 로고
    • The Runx gene family: Gain or loss of function in cancer
    • Blyth K, Cameron ER, Neil JC. The Runx gene family: gain or loss of function in cancer. Nat Rev Cancer 2005;5:376-87.
    • (2005) Nat Rev Cancer , vol.5 , pp. 376-387
    • Blyth, K.1    Cameron, E.R.2    Neil, J.C.3
  • 44
    • 37049024521 scopus 로고    scopus 로고
    • Runx2 disruption promotes immortalization and confers resistance to onco-gene-induced senescence in primary murine fibroblasts
    • Kilbey A, Blyth K, Wotton S, Terry A, Jenkins A, Bell M, et al. Runx2 disruption promotes immortalization and confers resistance to onco-gene-induced senescence in primary murine fibroblasts. Cancer Res 2007;67:11263-71.
    • (2007) Cancer Res , vol.67 , pp. 11263-11271
    • Kilbey, A.1    Blyth, K.2    Wotton, S.3    Terry, A.4    Jenkins, A.5    Bell, M.6
  • 45
    • 79959658018 scopus 로고    scopus 로고
    • The Hippo pathway transcriptional co-activator, YAP, is an ovarian cancer oncogene
    • Zhang X, George J, Deb S, Degoutin LJ, Takano EA, Fox SB, et al. The Hippo pathway transcriptional co-activator, YAP, is an ovarian cancer oncogene. Oncogene 2011;30:2810-22.
    • (2011) Oncogene , vol.30 , pp. 2810-2822
    • Zhang, X.1    George, J.2    Deb, S.3    Degoutin, L.J.4    Takano, E.A.5    Fox, S.B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.