RASSF1A directly antagonizes RhoA activity through the assembly of a Smurf1-mediated destruction complex to suppress tumorigenesis

Cancer Research

Volumn 76, Issue 7, 2016, Pages 1847-1859

  Lee, Min Goo ^a   Jeong, Seong In ^a   Ko, Kyung Phil ^a   Park, Soon Ki ^a   Ryu, Byung Kyu ^a   Kim, Ick Young ^a   Kim, Jeong Kook ^a   Chi, Sung Gil ^a  

^a Korea University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; GUANOSINE TRIPHOSPHATASE; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A; RHO FACTOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RHOTEKIN; SMAD UBIQUITINATION REGULATORY FACTOR 1; SMALL INTERFERING RNA; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; RASSF1 PROTEIN, HUMAN; SMURF1 PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CANCER INHIBITION; CANCER TISSUE; CARBOXY TERMINAL SEQUENCE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG RESISTANCE; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; EPITHELIAL MESENCHYMAL TRANSITION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; METASTASIS; MOUSE; NEOPLASM; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN MOTIF; SEQUENCE HOMOLOGY; TUMOR CELL; TUMOR INVASION; UBIQUITINATION; CARCINOGENESIS; GENETIC PREDISPOSITION; GENETIC TRANSFECTION; GENETICS; METABOLISM; TUMOR CELL LINE;

CARCINOGENESIS; CELL LINE, TUMOR; GENETIC PREDISPOSITION TO DISEASE; HUMANS; RHOA GTP-BINDING PROTEIN; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES;

EID: 84963967745     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-15-1752     Document Type: Article

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