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Volumn 8, Issue 27, 2016, Pages 1119-1127

Molecular pathological epidemiology in diabetes mellitus and risk of hepatocellular carcinoma

Author keywords

Diabetes mellitus; Hepatocellular carcinoma; Molecular mechanism; Molecular pathological epidemiology; Risk factor

Indexed keywords


EID: 84992395293     PISSN: None     EISSN: 19485182     Source Type: Journal    
DOI: 10.4254/wjh.v8.i27.1119     Document Type: Review
Times cited : (14)

References (100)
  • 1
    • 77951879560 scopus 로고    scopus 로고
    • The molecular pathology of cancer
    • PMID: 20351699
    • Harris TJ, McCormick F. The molecular pathology of cancer. Nat Rev Clin Oncol 2010; 7: 251-265 [PMID: 20351699 DOI: 10.1038/nrclinonc.2010.41]
    • (2010) Nat Rev Clin Oncol , vol.7 , pp. 251-265
    • Harris, T.J.1    McCormick, F.2
  • 2
    • 84898056935 scopus 로고    scopus 로고
    • Molecular epidemiology of infectious laryngotracheitis: a review
    • PMID: 24460399
    • Menendez KR, García M, Spatz S, Tablante NL. Molecular epidemiology of infectious laryngotracheitis: a review. Avian Pathol 2014; 43: 108-117 [PMID: 24460399 DOI: 10.1080/03079457.201 4.886004]
    • (2014) Avian Pathol , vol.43 , pp. 108-117
    • Menendez, K.R.1    García, M.2    Spatz, S.3    Tablante, N.L.4
  • 3
    • 0030809616 scopus 로고    scopus 로고
    • Molecular epidemiology in cancer research (review)
    • PMID: 21528304
    • Izzotti A, Neri M, Vecchio D, Puntoni R. Molecular epidemiology in cancer research (review). Int J Oncol 1997; 11: 1053-1069 [PMID: 21528304]
    • (1997) Int J Oncol , vol.11 , pp. 1053-1069
    • Izzotti, A.1    Neri, M.2    Vecchio, D.3    Puntoni, R.4
  • 4
    • 84939229306 scopus 로고    scopus 로고
    • Year in review 2014: basic science and epidemiology
    • PMID: 25977391
    • Lloyd C, Cullinan P. Year in review 2014: basic science and epidemiology. Thorax 2015; 70: 581-584 [PMID: 25977391 DOI: 10.1136/thoraxjnl-2015-207222]
    • (2015) Thorax , vol.70 , pp. 581-584
    • Lloyd, C.1    Cullinan, P.2
  • 5
    • 77949928737 scopus 로고    scopus 로고
    • Lifestyle factors and microsatellite instability in colorectal cancer: the evolving field of molecular pathological epidemiology
    • PMID: 20208016
    • Ogino S, Stampfer M. Lifestyle factors and microsatellite instability in colorectal cancer: the evolving field of molecular pathological epidemiology. J Natl Cancer Inst 2010; 102: 365-367 [PMID: 20208016 DOI: 10.1093/jnci/djq031]
    • (2010) J Natl Cancer Inst , vol.102 , pp. 365-367
    • Ogino, S.1    Stampfer, M.2
  • 6
    • 79851511414 scopus 로고    scopus 로고
    • Molecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field
    • PMID: 21036793
    • Ogino S, Chan AT, Fuchs CS, Giovannucci E. Molecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field. Gut 2011; 60: 397-411 [PMID: 21036793 DOI: 10.1136/gut.2010.217182]
    • (2011) Gut , vol.60 , pp. 397-411
    • Ogino, S.1    Chan, A.T.2    Fuchs, C.S.3    Giovannucci, E.4
  • 8
    • 79955369630 scopus 로고    scopus 로고
    • Association of CTNNB1 (beta-catenin) alterations, body mass index, and physical activity with survival in patients with colorectal cancer
    • PMID: 21521850
    • Morikawa T, Kuchiba A, Yamauchi M, Meyerhardt JA, Shima K, Nosho K, Chan AT, Giovannucci E, Fuchs CS, Ogino S. Association of CTNNB1 (beta-catenin) alterations, body mass index, and physical activity with survival in patients with colorectal cancer. JAMA 2011; 305: 1685-1694 [PMID: 21521850 DOI: 10.1001/jama.2011.513]
    • (2011) JAMA , vol.305 , pp. 1685-1694
    • Morikawa, T.1    Kuchiba, A.2    Yamauchi, M.3    Meyerhardt, J.A.4    Shima, K.5    Nosho, K.6    Chan, A.T.7    Giovannucci, E.8    Fuchs, C.S.9    Ogino, S.10
  • 10
    • 84930924610 scopus 로고    scopus 로고
    • Molecular pathological epidemiology: an interdisciplinary field for study of hepatocellular carcinoma
    • Gao C. Molecular pathological epidemiology: an interdisciplinary field for study of hepatocellular carcinoma. Austin J Gastroenterol 2015; 2: 1040
    • (2015) Austin J Gastroenterol , vol.2 , pp. 1040
    • Gao, C.1
  • 11
    • 84855792427 scopus 로고    scopus 로고
    • Cancer statistics, 2012
    • PMID: 22237781
    • Siegel R, Naishadham D, Jemal A. Cancer statistics, 2012. CA Cancer J Clin 2012; 62: 10-29 [PMID: 22237781 DOI: 10.3322/caac.20138]
    • (2012) CA Cancer J Clin , vol.62 , pp. 10-29
    • Siegel, R.1    Naishadham, D.2    Jemal, A.3
  • 12
    • 84876566606 scopus 로고    scopus 로고
    • Increased international normalized ratio level in hepatocellular carcinoma patients with diabetes mellitus
    • PMID: 23613635
    • Zhang H, Gao C, Fang L, Yao SK. Increased international normalized ratio level in hepatocellular carcinoma patients with diabetes mellitus. World J Gastroenterol 2013; 19: 2395-2403 [PMID: 23613635 DOI: 10.3748/wjg.v19.i15.2395]
    • (2013) World J Gastroenterol , vol.19 , pp. 2395-2403
    • Zhang, H.1    Gao, C.2    Fang, L.3    Yao, S.K.4
  • 14
    • 0642303165 scopus 로고    scopus 로고
    • The continuing increase in the incidence of hepatocellular carcinoma in the United States: an update
    • PMID: 14623619
    • El-Serag HB, Davila JA, Petersen NJ, McGlynn KA. The continuing increase in the incidence of hepatocellular carcinoma in the United States: an update. Ann Intern Med 2003; 139: 817-823 [PMID: 14623619]
    • (2003) Ann Intern Med , vol.139 , pp. 817-823
    • El-Serag, H.B.1    Davila, J.A.2    Petersen, N.J.3    McGlynn, K.A.4
  • 15
    • 63049111543 scopus 로고    scopus 로고
    • Hepatocellular carcinoma in the Asia pacific region
    • PMID: 19220670
    • Yuen MF, Hou JL, Chutaputti A. Hepatocellular carcinoma in the Asia pacific region. J Gastroenterol Hepatol 2009; 24: 346-353 [PMID: 19220670 DOI: 10.1111/j.1440-1746.2009.05784.x]
    • (2009) J Gastroenterol Hepatol , vol.24 , pp. 346-353
    • Yuen, M.F.1    Hou, J.L.2    Chutaputti, A.3
  • 16
    • 15544382574 scopus 로고    scopus 로고
    • Diabetes increases the risk of hepatocellular carcinoma in the United States: a population based case control study
    • PMID: 15753540
    • Davila JA, Morgan RO, Shaib Y, McGlynn KA, El-Serag HB. Diabetes increases the risk of hepatocellular carcinoma in the United States: a population based case control study. Gut 2005; 54: 533-539 [PMID: 15753540 DOI: 10.1136/gut.2004.052167]
    • (2005) Gut , vol.54 , pp. 533-539
    • Davila, J.A.1    Morgan, R.O.2    Shaib, Y.3    McGlynn, K.A.4    El-Serag, H.B.5
  • 17
    • 40049097359 scopus 로고    scopus 로고
    • Liver cirrhosis
    • PMID: 18328931
    • Schuppan D, Afdhal NH. Liver cirrhosis. Lancet 2008; 371: 838-851 [PMID: 18328931 DOI: 10.1016/S0140-6736(08)60383-9]
    • (2008) Lancet , vol.371 , pp. 838-851
    • Schuppan, D.1    Afdhal, N.H.2
  • 18
    • 84960392992 scopus 로고    scopus 로고
    • Risk factors and patterns of early recurrence after curative hepatectomy for hepatocellular carcinoma
    • PMID: 26979637
    • Hirokawa F, Hayashi M, Asakuma M, Shimizu T, Inoue Y, Uchiyama K. Risk factors and patterns of early recurrence after curative hepatectomy for hepatocellular carcinoma. Surg Oncol 2016; 25: 24-29 [PMID: 26979637 DOI: 10.1016/j.suronc.2015. 12.002]
    • (2016) Surg Oncol , vol.25 , pp. 24-29
    • Hirokawa, F.1    Hayashi, M.2    Asakuma, M.3    Shimizu, T.4    Inoue, Y.5    Uchiyama, K.6
  • 20
    • 84886391056 scopus 로고    scopus 로고
    • Potential role of diabetes mellitus in the progression of cirrhosis to hepatocellular carcinoma: a cross-sectional case-control study from Chinese patients with HBV infection
    • PMID: 23924496
    • Gao C, Fang L, Zhao HC, Li JT, Yao SK. Potential role of diabetes mellitus in the progression of cirrhosis to hepatocellular carcinoma: a cross-sectional case-control study from Chinese patients with HBV infection. Hepatobiliary Pancreat Dis Int 2013; 12: 385-393 [PMID: 23924496]
    • (2013) Hepatobiliary Pancreat Dis Int , vol.12 , pp. 385-393
    • Gao, C.1    Fang, L.2    Zhao, H.C.3    Li, J.T.4    Yao, S.K.5
  • 21
    • 70350284071 scopus 로고    scopus 로고
    • Diabetes mellitus: a "true" independent risk factor for hepatocellular carcinoma?
    • PMID: 19822488
    • Gao C, Yao SK. Diabetes mellitus: a "true" independent risk factor for hepatocellular carcinoma? Hepatobiliary Pancreat Dis Int 2009; 8: 465-473 [PMID: 19822488]
    • (2009) Hepatobiliary Pancreat Dis Int , vol.8 , pp. 465-473
    • Gao, C.1    Yao, S.K.2
  • 22
    • 77957607698 scopus 로고    scopus 로고
    • Diabetes mellitus and hepatocellular carcinoma: comparison of Chinese patients with and without HBV-related cirrhosis
    • PMID: 20845516
    • Gao C, Zhao HC, Li JT, Yao SK. Diabetes mellitus and hepatocellular carcinoma: comparison of Chinese patients with and without HBV-related cirrhosis. World J Gastroenterol 2010; 16: 4467-4475 [PMID: 20845516]
    • (2010) World J Gastroenterol , vol.16 , pp. 4467-4475
    • Gao, C.1    Zhao, H.C.2    Li, J.T.3    Yao, S.K.4
  • 23
    • 84871384034 scopus 로고    scopus 로고
    • Metformin and reduced risk of hepatocellular carcinoma in diabetic patients: a meta-analysis
    • PMID: 23137049
    • Zhang H, Gao C, Fang L, Zhao HC, Yao SK. Metformin and reduced risk of hepatocellular carcinoma in diabetic patients: a meta-analysis. Scand J Gastroenterol 2013; 48: 78-87 [PMID: 23137049 DOI: 10.3109/00365521.2012.719926]
    • (2013) Scand J Gastroenterol , vol.48 , pp. 78-87
    • Zhang, H.1    Gao, C.2    Fang, L.3    Zhao, H.C.4    Yao, S.K.5
  • 25
    • 0034755174 scopus 로고    scopus 로고
    • Prospective study of diabetes mellitus and liver cancer in Japan
    • PMID: 11747142
    • Fujino Y, Mizoue T, Tokui N, Yoshimura T. Prospective study of diabetes mellitus and liver cancer in Japan. Diabetes Metab Res Rev 2001; 17: 374-379 [PMID: 11747142]
    • (2001) Diabetes Metab Res Rev , vol.17 , pp. 374-379
    • Fujino, Y.1    Mizoue, T.2    Tokui, N.3    Yoshimura, T.4
  • 26
    • 0034881446 scopus 로고    scopus 로고
    • The role of diabetes in hepatocellular carcinoma: a case-control study among United States Veterans
    • PMID: 11513191
    • El-Serag HB, Richardson PA, Everhart JE. The role of diabetes in hepatocellular carcinoma: a case-control study among United States Veterans. Am J Gastroenterol 2001; 96: 2462-2467 [PMID: 11513191 DOI: 10.1111/j.1572-0241.2001.04054.x]
    • (2001) Am J Gastroenterol , vol.96 , pp. 2462-2467
    • El-Serag, H.B.1    Richardson, P.A.2    Everhart, J.E.3
  • 27
    • 33644764668 scopus 로고    scopus 로고
    • Risk factors for primary hepatocellular carcinoma in black and white Americans in 2000
    • PMID: 16527700
    • Yu L, Sloane DA, Guo C, Howell CD. Risk factors for primary hepatocellular carcinoma in black and white Americans in 2000. Clin Gastroenterol Hepatol 2006; 4: 355-360 [PMID: 16527700 DOI: 10.1016/j.cgh.2005.12.022]
    • (2006) Clin Gastroenterol Hepatol , vol.4 , pp. 355-360
    • Yu, L.1    Sloane, D.A.2    Guo, C.3    Howell, C.D.4
  • 28
    • 0014761971 scopus 로고
    • Cancer mortality among diabetics
    • PMID: 11515436
    • Kessler II. Cancer mortality among diabetics. J Natl Cancer Inst 1970; 44: 673-686 [PMID: 11515436]
    • (1970) J Natl Cancer Inst , vol.44 , pp. 673-686
    • Kessler, I.I.1
  • 29
    • 0020076114 scopus 로고
    • Subsequent cancer risk in the incidence cohort of Rochester, Minnesota, residents with diabetes mellitus
    • PMID: 7068798
    • Ragozzino M, Melton LJ, Chu CP, Palumbo PJ. Subsequent cancer risk in the incidence cohort of Rochester, Minnesota, residents with diabetes mellitus. J Chronic Dis 1982; 35: 13-19 [PMID: 7068798]
    • (1982) J Chronic Dis , vol.35 , pp. 13-19
    • Ragozzino, M.1    Melton, L.J.2    Chu, C.P.3    Palumbo, P.J.4
  • 30
    • 0023723658 scopus 로고
    • A case-control study of primary hepatocellular carcinoma in Taiwan
    • PMID: 2844388
    • Lu SN, Lin TM, Chen CJ, Chen JS, Liaw YF, Chang WY, Hsu ST. A case-control study of primary hepatocellular carcinoma in Taiwan. Cancer 1988; 62: 2051-2055 [PMID: 2844388]
    • (1988) Cancer , vol.62 , pp. 2051-2055
    • Lu, S.N.1    Lin, T.M.2    Chen, C.J.3    Chen, J.S.4    Liaw, Y.F.5    Chang, W.Y.6    Hsu, S.T.7
  • 32
    • 0842321807 scopus 로고    scopus 로고
    • Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma
    • PMID: 14762783
    • El-Serag HB, Tran T, Everhart JE. Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma. Gastroenterology 2004; 126: 460-468 [PMID: 14762783]
    • (2004) Gastroenterology , vol.126 , pp. 460-468
    • El-Serag, H.B.1    Tran, T.2    Everhart, J.E.3
  • 33
    • 84973453868 scopus 로고    scopus 로고
    • Diabetes Mellitus Increases Risk of Hepatocellular Carcinoma in Chronic Hepatitis C Virus Patients: A Systematic Review
    • PMID: 26703125
    • Dyal HK, Aguilar M, Bartos G, Holt EW, Bhuket T, Liu B, Cheung R, Wong RJ. Diabetes Mellitus Increases Risk of Hepatocellular Carcinoma in Chronic Hepatitis C Virus Patients: A Systematic Review. Dig Dis Sci 2016; 61: 636-645 [PMID: 26703125 DOI: 10.1007/s10620-015-3983-3]
    • (2016) Dig Dis Sci , vol.61 , pp. 636-645
    • Dyal, H.K.1    Aguilar, M.2    Bartos, G.3    Holt, E.W.4    Bhuket, T.5    Liu, B.6    Cheung, R.7    Wong, R.J.8
  • 35
    • 67650456227 scopus 로고    scopus 로고
    • The impact of type 2 diabetes on the development of hepatocellular carcinoma in different viral hepatitis statuses
    • PMID: 19549812
    • Wang CS, Yao WJ, Chang TT, Wang ST, Chou P. The impact of type 2 diabetes on the development of hepatocellular carcinoma in different viral hepatitis statuses. Cancer Epidemiol Biomarkers Prev 2009; 18: 2054-2060 [PMID: 19549812 DOI: 10.1158/1055-9965.EPI-08-1131]
    • (2009) Cancer Epidemiol Biomarkers Prev , vol.18 , pp. 2054-2060
    • Wang, C.S.1    Yao, W.J.2    Chang, T.T.3    Wang, S.T.4    Chou, P.5
  • 36
    • 84984548367 scopus 로고    scopus 로고
    • Metabolic factors and risk of hepatocellular carcinoma by chronic hepatitis B/C infection: a follow-up study in Taiwan
    • PMID: 18505690
    • Chen CL, Yang HI, Yang WS, Liu CJ, Chen PJ, You SL, Wang LY, Sun CA, Lu SN, Chen DS, Chen CJ. Metabolic factors and risk of hepatocellular carcinoma by chronic hepatitis B/C infection: a follow-up study in Taiwan. Gastroenterology 2008; 135: 111-121 [PMID: 18505690 DOI: 10.1053/j.gastro.2008.03.073]
    • (2008) Gastroenterology , vol.135 , pp. 111-121
    • Chen, C.L.1    Yang, H.I.2    Yang, W.S.3    Liu, C.J.4    Chen, P.J.5    You, S.L.6    Wang, L.Y.7    Sun, C.A.8    Lu, S.N.9    Chen, D.S.10    Chen, C.J.11
  • 38
    • 84863749909 scopus 로고    scopus 로고
    • Diabetes, hepatitis virus infection and hepatocellular carcinoma: A case-control study in hepatitis endemic area
    • PMID: 22469194
    • Ko WH, Chiu SY, Yang KC, Chen HH. Diabetes, hepatitis virus infection and hepatocellular carcinoma: A case-control study in hepatitis endemic area. Hepatol Res 2012; 42: 774-781 [PMID: 22469194 DOI: 10.1111/j.1872-034X.2012.00979.x]
    • (2012) Hepatol Res , vol.42 , pp. 774-781
    • Ko, W.H.1    Chiu, S.Y.2    Yang, K.C.3    Chen, H.H.4
  • 39
    • 70349232293 scopus 로고    scopus 로고
    • Diabetes pattern on the 75 g oral glucose tolerance test is a risk factor for hepatocellular carcinoma in patients with hepatitis C virus
    • PMID: 19422477
    • Konishi I, Hiasa Y, Shigematsu S, Hirooka M, Furukawa S, Abe M, Matsuura B, Michitaka K, Horiike N, Onji M. Diabetes pattern on the 75 g oral glucose tolerance test is a risk factor for hepatocellular carcinoma in patients with hepatitis C virus. Liver Int 2009; 29: 1194-1201 [PMID: 19422477 DOI: 10.1111/j.1478-3231.2009.02043.x]
    • (2009) Liver Int , vol.29 , pp. 1194-1201
    • Konishi, I.1    Hiasa, Y.2    Shigematsu, S.3    Hirooka, M.4    Furukawa, S.5    Abe, M.6    Matsuura, B.7    Michitaka, K.8    Horiike, N.9    Onji, M.10
  • 41
    • 77954564293 scopus 로고    scopus 로고
    • A brief history of pathology: Preface to a forthcoming series that highlights milestones in the evolution of pathology as a discipline
    • PMID: 20499087
    • van den Tweel JG, Taylor CR. A brief history of pathology: Preface to a forthcoming series that highlights milestones in the evolution of pathology as a discipline. Virchows Arch 2010; 457: 3-10 [PMID: 20499087 DOI: 10.1007/s00428-010-0934-4]
    • (2010) Virchows Arch , vol.457 , pp. 3-10
    • van den Tweel, J.G.1    Taylor, C.R.2
  • 42
    • 84885578558 scopus 로고    scopus 로고
    • History and current state of pathology in China
    • PMID: 23881278
    • Jiang C, Gu J. History and current state of pathology in China. Virchows Arch 2013; 463: 599-608 [PMID: 23881278 DOI: 10.1007/s00428-013-1449-6]
    • (2013) Virchows Arch , vol.463 , pp. 599-608
    • Jiang, C.1    Gu, J.2
  • 43
    • 0025130361 scopus 로고
    • Molecular pathology of type 1 diabetes
    • PMID: 2233244
    • Campbell IL, Harrison LC. Molecular pathology of type 1 diabetes. Mol Biol Med 1990; 7: 299-309 [PMID: 2233244]
    • (1990) Mol Biol Med , vol.7 , pp. 299-309
    • Campbell, I.L.1    Harrison, L.C.2
  • 44
    • 0036137987 scopus 로고    scopus 로고
    • Understanding autoimmune diabetes: insights from mouse models
    • PMID: 11796264
    • Adorini L, Gregori S, Harrison LC. Understanding autoimmune diabetes: insights from mouse models. Trends Mol Med 2002; 8: 31-38 [PMID: 11796264]
    • (2002) Trends Mol Med , vol.8 , pp. 31-38
    • Adorini, L.1    Gregori, S.2    Harrison, L.C.3
  • 47
    • 67349245787 scopus 로고    scopus 로고
    • New insights into the aetiology of colorectal cancer from genome-wide association studies
    • PMID: 19434079
    • Tenesa A, Dunlop MG. New insights into the aetiology of colorectal cancer from genome-wide association studies. Nat Rev Genet 2009; 10: 353-358 [PMID: 19434079 DOI: 10.1038/nrg2574]
    • (2009) Nat Rev Genet , vol.10 , pp. 353-358
    • Tenesa, A.1    Dunlop, M.G.2
  • 48
    • 77951585057 scopus 로고    scopus 로고
    • Architecture of inherited susceptibility to common cancer
    • PMID: 20414203
    • Fletcher O, Houlston RS. Architecture of inherited susceptibility to common cancer. Nat Rev Cancer 2010; 10: 353-361 [PMID: 20414203 DOI: 10.1038/nrc2840]
    • (2010) Nat Rev Cancer , vol.10 , pp. 353-361
    • Fletcher, O.1    Houlston, R.S.2
  • 49
    • 21244481313 scopus 로고    scopus 로고
    • Insulin-like growth factor-I and risk of type 2 diabetes and coronary heart disease: molecular epidemiology
    • PMID: 15879687
    • Sandhu MS. Insulin-like growth factor-I and risk of type 2 diabetes and coronary heart disease: molecular epidemiology. Endocr Dev 2005; 9: 44-54 [PMID: 15879687 DOI: 10.1159/000085755]
    • (2005) Endocr Dev , vol.9 , pp. 44-54
    • Sandhu, M.S.1
  • 50
    • 84891763374 scopus 로고    scopus 로고
    • Epidemiology and molecular mechanisms tying obesity, diabetes, and the metabolic syndrome with cancer
    • PMID: 23882051
    • Gallagher EJ, LeRoith D. Epidemiology and molecular mechanisms tying obesity, diabetes, and the metabolic syndrome with cancer. Diabetes Care 2013; 36 Suppl 2: S233-S239 [PMID: 23882051 DOI: 10.2337/dcS13-2001]
    • (2013) Diabetes Care , vol.36 , pp. S233-S239
    • Gallagher, E.J.1    LeRoith, D.2
  • 51
    • 84888589060 scopus 로고    scopus 로고
    • The merits of subtyping obesity: one size does not fit all
    • PMID: rfseq 24189835
    • Field AE, Camargo CA, Ogino S. The merits of subtyping obesity: one size does not fit all. JAMA 2013; 310: 2147-2148 [PMID: rfseq 24189835 DOI: 10.1001/jama.2013.281501]
    • (2013) JAMA , vol.310 , pp. 2147-2148
    • Field, A.E.1    Camargo, C.A.2    Ogino, S.3
  • 52
    • 84949671860 scopus 로고    scopus 로고
    • Relationship between hOGG1 Ser326Cys gene polymorphism and coronary artery lesions in patients with diabetes mellitus
    • PMID: 26770476
    • Wu ZY, Wang MH, Qi HM, Wu MH, Ge YZ, Li HT. Relationship between hOGG1 Ser326Cys gene polymorphism and coronary artery lesions in patients with diabetes mellitus. Int J Clin Exp Med 2015; 8: 18629-18637 [PMID: 26770476]
    • (2015) Int J Clin Exp Med , vol.8 , pp. 18629-18637
    • Wu, Z.Y.1    Wang, M.H.2    Qi, H.M.3    Wu, M.H.4    Ge, Y.Z.5    Li, H.T.6
  • 53
    • 84872898597 scopus 로고    scopus 로고
    • Molecular pathology of colorectal carcinoma. A systematic review centred on the new role of the pathologist
    • PMID: 23547429
    • Remo A, Pancione M, Zanella C, Vendraminelli R. Molecular pathology of colorectal carcinoma. A systematic review centred on the new role of the pathologist. Pathologica 2012; 104: 432-441 [PMID: 23547429]
    • (2012) Pathologica , vol.104 , pp. 432-441
    • Remo, A.1    Pancione, M.2    Zanella, C.3    Vendraminelli, R.4
  • 54
    • 77958470619 scopus 로고    scopus 로고
    • Gastrointestinal stromal tumors: review on morphology, molecular pathology, diagnostics, prognosis and treatment options
    • PMID: 21086937
    • Paral J, Slaninka I, Kalabova H, Hadzi-Nikolov D. Gastrointestinal stromal tumors: review on morphology, molecular pathology, diagnostics, prognosis and treatment options. Acta Gastroenterol Belg 2010; 73: 349-359 [PMID: 21086937]
    • (2010) Acta Gastroenterol Belg , vol.73 , pp. 349-359
    • Paral, J.1    Slaninka, I.2    Kalabova, H.3    Hadzi-Nikolov, D.4
  • 55
    • 84951798655 scopus 로고    scopus 로고
    • Extracranial metastasis of gliobastoma: Three illustrative cases and current review of the molecular pathology and management strategies
    • PMID: 26137254
    • Ray A, Manjila S, Hdeib AM, Radhakrishnan A, Nock CJ, Cohen ML, Sloan AE. Extracranial metastasis of gliobastoma: Three illustrative cases and current review of the molecular pathology and management strategies. Mol Clin Oncol 2015; 3: 479-486 [PMID: 26137254 DOI: 10.3892/mco.2015.494]
    • (2015) Mol Clin Oncol , vol.3 , pp. 479-486
    • Ray, A.1    Manjila, S.2    Hdeib, A.M.3    Radhakrishnan, A.4    Nock, C.J.5    Cohen, M.L.6    Sloan, A.E.7
  • 56
    • 37149041833 scopus 로고    scopus 로고
    • Molecular classification and correlates in colorectal cancer
    • PMID: 18165277
    • Ogino S, Goel A. Molecular classification and correlates in colorectal cancer. J Mol Diagn 2008; 10: 13-27 [PMID: 18165277 DOI: 10.2353/jmoldx.2008.070082]
    • (2008) J Mol Diagn , vol.10 , pp. 13-27
    • Ogino, S.1    Goel, A.2
  • 57
    • 82955189198 scopus 로고    scopus 로고
    • How novel molecular diagnostic technologies and biomarkers are revolutionizing genetic testing and patient care
    • PMID: 22133117
    • Baudhuin LM, Donato LJ, Uphoff TS. How novel molecular diagnostic technologies and biomarkers are revolutionizing genetic testing and patient care. Expert Rev Mol Diagn 2012; 12: 25-37 [PMID: 22133117 DOI: 10.1586/ERM.11.85]
    • (2012) Expert Rev Mol Diagn , vol.12 , pp. 25-37
    • Baudhuin, L.M.1    Donato, L.J.2    Uphoff, T.S.3
  • 58
    • 74749106342 scopus 로고    scopus 로고
    • Novel clinico-genome network modeling for revolutionizing genotype-phenotype-based personalized cancer care
    • PMID: 20014921
    • Roukos DH. Novel clinico-genome network modeling for revolutionizing genotype-phenotype-based personalized cancer care. Expert Rev Mol Diagn 2010; 10: 33-48 [PMID: 20014921 DOI: 10.1586/erm.09.69]
    • (2010) Expert Rev Mol Diagn , vol.10 , pp. 33-48
    • Roukos, D.H.1
  • 59
    • 80052760956 scopus 로고    scopus 로고
    • Biomarkers research in Europe: focus on personalized medicine
    • PMID: 21902529
    • Metodiev MV. Biomarkers research in Europe: focus on personalized medicine. Expert Rev Mol Diagn 2011; 11: 689-690 [PMID: 21902529 DOI: 10.1586/erm.11.55]
    • (2011) Expert Rev Mol Diagn , vol.11 , pp. 689-690
    • Metodiev, M.V.1
  • 60
    • 42549084786 scopus 로고    scopus 로고
    • Targeted therapy of cancer: new roles for pathologists in colorectal cancer
    • PMID: 18437170
    • Hamilton SR. Targeted therapy of cancer: new roles for pathologists in colorectal cancer. Mod Pathol 2008; 21 Suppl 2: S23-S30 [PMID: 18437170 DOI: 10.1038/modpathol.2008.14]
    • (2008) Mod Pathol , vol.21 , pp. S23-S30
    • Hamilton, S.R.1
  • 62
    • 79954592811 scopus 로고    scopus 로고
    • A national agenda for the future of pathology in personalized medicine: report of the proceedings of a meeting at the Banbury Conference Center on genome-era pathology, precision diagnostics, and preemptive care: a stakeholder summit
    • PMID: 21502420
    • Tonellato PJ, Crawford JM, Boguski MS, Saffitz JE. A national agenda for the future of pathology in personalized medicine: report of the proceedings of a meeting at the Banbury Conference Center on genome-era pathology, precision diagnostics, and preemptive care: a stakeholder summit. Am J Clin Pathol 2011; 135: 668-672 [PMID: 21502420 DOI: 10.1309/AJCP9GDNLWB4GACI]
    • (2011) Am J Clin Pathol , vol.135 , pp. 668-672
    • Tonellato, P.J.1    Crawford, J.M.2    Boguski, M.S.3    Saffitz, J.E.4
  • 65
    • 84934774866 scopus 로고    scopus 로고
    • Evaluation of Hormone Receptor Status (ER/PR/HER2-neu) in Breast Cancer in Pakistan
    • PMID: 26160085
    • Pervaiz F, Rehmani S, Majid S, Anwar H. Evaluation of Hormone Receptor Status (ER/PR/HER2-neu) in Breast Cancer in Pakistan. J Pak Med Assoc 2015; 65: 747-752 [PMID: 26160085]
    • (2015) J Pak Med Assoc , vol.65 , pp. 747-752
    • Pervaiz, F.1    Rehmani, S.2    Majid, S.3    Anwar, H.4
  • 66
    • 85018223676 scopus 로고    scopus 로고
    • Shades of T790M: Intratumor Heterogeneity in EGFR-Mutant Lung Cancer
    • PMID: 26152920
    • Ichihara E, Lovly CM. Shades of T790M: Intratumor Heterogeneity in EGFR-Mutant Lung Cancer. Cancer Discov 2015; 5: 694-696 [PMID: 26152920 DOI: 10.1158/2159-8290.CD-15-0616]
    • (2015) Cancer Discov , vol.5 , pp. 694-696
    • Ichihara, E.1    Lovly, C.M.2
  • 67
    • 84930884839 scopus 로고    scopus 로고
    • Clinical features and mutation status of EGFR, KRAS, BRAF, EML4-ALK and ROS1 between surgical resection samples and non surgical resection samples in lung cancer
    • PMID: 26101643
    • Li W, Qu J, Xu Z. Clinical features and mutation status of EGFR, KRAS, BRAF, EML4-ALK and ROS1 between surgical resection samples and non surgical resection samples in lung cancer. J Thorac Dis 2015; 7: 875-880 [PMID: 26101643 DOI: 10.3978/j.issn.2072-1439.2015.04.49]
    • (2015) J Thorac Dis , vol.7 , pp. 875-880
    • Li, W.1    Qu, J.2    Xu, Z.3
  • 68
    • 84925678885 scopus 로고    scopus 로고
    • Systematic review of the predictive effect of MSI status in colorectal cancer patients undergoing 5FU-based chemotherapy
    • PMID: 25884995
    • Webber EM, Kauffman TL, O'Connor E, Goddard KA. Systematic review of the predictive effect of MSI status in colorectal cancer patients undergoing 5FU-based chemotherapy. BMC Cancer 2015; 15: 156 [PMID: 25884995 DOI: 10.1186/s12885-015-1093-4]
    • (2015) BMC Cancer , vol.15 , pp. 156
    • Webber, E.M.1    Kauffman, T.L.2    O'Connor, E.3    Goddard, K.A.4
  • 70
    • 84924038002 scopus 로고    scopus 로고
    • Treatment with the PARP inhibitor, niraparib, sensitizes colorectal cancer cell lines to irinotecan regardless of MSI/MSS status
    • PMID: 25685067
    • Genther Williams SM, Kuznicki AM, Andrade P, Dolinski BM, Elbi C, O'Hagan RC, Toniatti C. Treatment with the PARP inhibitor, niraparib, sensitizes colorectal cancer cell lines to irinotecan regardless of MSI/MSS status. Cancer Cell Int 2015; 15: 14 [PMID: 25685067 DOI: 10.1186/s12935-015-0162-8]
    • (2015) Cancer Cell Int , vol.15 , pp. 14
    • Genther Williams, S.M.1    Kuznicki, A.M.2    Andrade, P.3    Dolinski, B.M.4    Elbi, C.5    O'Hagan, R.C.6    Toniatti, C.7
  • 72
    • 40849139208 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • PMID: 18337604
    • Esteller M. Epigenetics in cancer. N Engl J Med 2008; 358: 1148-1159 [PMID: 18337604 DOI: 10.1056/NEJMra072067]
    • (2008) N Engl J Med , vol.358 , pp. 1148-1159
    • Esteller, M.1
  • 75
    • 0030474858 scopus 로고    scopus 로고
    • p53 immunoreaction in hepatocellular carcinoma and its relationship to etiologic factors. A fine needle aspiration study
    • PMID: 8960021
    • Ojanguren I, Castellà E, Llatjós M, Ariza A, Navas Palacios JJ. p53 immunoreaction in hepatocellular carcinoma and its relationship to etiologic factors. A fine needle aspiration study. Acta Cytol 1996; 40: 1148-1153 [PMID: 8960021]
    • (1996) Acta Cytol , vol.40 , pp. 1148-1153
    • Ojanguren, I.1    Castellà, E.2    Llatjós, M.3    Ariza, A.4    Navas Palacios, J.J.5
  • 76
    • 74549167737 scopus 로고    scopus 로고
    • Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression
    • PMID: 20141834
    • Park EJ, Lee JH, Yu GY, He G, Ali SR, Holzer RG, Osterreicher CH, Takahashi H, Karin M. Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression. Cell 2010; 140: 197-208 [PMID: 20141834 DOI: 10.1016/j.cell.2009.12.052]
    • (2010) Cell , vol.140 , pp. 197-208
    • Park, E.J.1    Lee, J.H.2    Yu, G.Y.3    He, G.4    Ali, S.R.5    Holzer, R.G.6    Osterreicher, C.H.7    Takahashi, H.8    Karin, M.9
  • 77
    • 84923199734 scopus 로고    scopus 로고
    • Leptin signaling molecular actions and drug target in hepatocellular carcinoma
    • PMID: 25484575
    • Jiang N, Sun R, Sun Q. Leptin signaling molecular actions and drug target in hepatocellular carcinoma. Drug Des Devel Ther 2014; 8: 2295-2302 [PMID: 25484575 DOI: 10.2147/DDDT.S69004]
    • (2014) Drug Des Devel Ther , vol.8 , pp. 2295-2302
    • Jiang, N.1    Sun, R.2    Sun, Q.3
  • 78
    • 84859212951 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • PMID: 22353262
    • Forner A, Llovet JM, Bruix J. Hepatocellular carcinoma. Lancet 2012; 379: 1245-1255 [PMID: 22353262 DOI: 10.1016/S0140-6736(11)61347-0]
    • (2012) Lancet , vol.379 , pp. 1245-1255
    • Forner, A.1    Llovet, J.M.2    Bruix, J.3
  • 79
    • 81255168068 scopus 로고    scopus 로고
    • dbHCCvar: a comprehensive database of human genetic variations in hepatocellular carcinoma
    • PMID: 21936021
    • Yu XJ, Fang F, Tang CL, Yao L, Yu L, Yu L. dbHCCvar: a comprehensive database of human genetic variations in hepatocellular carcinoma. Hum Mutat 2011; 32: E2308-E2316 [PMID: 21936021 DOI: 10.1002/humu.21595]
    • (2011) Hum Mutat , vol.32 , pp. E2308-E2316
    • Yu, X.J.1    Fang, F.2    Tang, C.L.3    Yao, L.4    Yu, L.5    Yu, L.6
  • 80
    • 79960943280 scopus 로고    scopus 로고
    • Polymorphisms of tumor necrosis factor-alpha and hepatocellular carcinoma risk: a HuGE systematic review and metaanalysis
    • PMID: 21336601
    • Wei Y, Liu F, Li B, Chen X, Ma Y, Yan L, Wen T, Xu M, Wang W, Yang J. Polymorphisms of tumor necrosis factor-alpha and hepatocellular carcinoma risk: a HuGE systematic review and metaanalysis. Dig Dis Sci 2011; 56: 2227-2236 [PMID: 21336601 DOI: 10.1007/s10620-011-1617-y]
    • (2011) Dig Dis Sci , vol.56 , pp. 2227-2236
    • Wei, Y.1    Liu, F.2    Li, B.3    Chen, X.4    Ma, Y.5    Yan, L.6    Wen, T.7    Xu, M.8    Wang, W.9    Yang, J.10
  • 81
    • 80054841311 scopus 로고    scopus 로고
    • Interleukin-10 gene polymorphisms and hepatocellular carcinoma susceptibility: a meta-analysis
    • PMID: 22025883
    • Wei YG, Liu F, Li B, Chen X, Ma Y, Yan LN, Wen TF, Xu MQ, Wang WT, Yang JY. Interleukin-10 gene polymorphisms and hepatocellular carcinoma susceptibility: a meta-analysis. World J Gastroenterol 2011; 17: 3941-3947 [PMID: 22025883 DOI: 10.3748/wjg.v17.i34.3941]
    • (2011) World J Gastroenterol , vol.17 , pp. 3941-3947
    • Wei, Y.G.1    Liu, F.2    Li, B.3    Chen, X.4    Ma, Y.5    Yan, L.N.6    Wen, T.F.7    Xu, M.Q.8    Wang, W.T.9    Yang, J.Y.10
  • 82
    • 77955850169 scopus 로고    scopus 로고
    • Null genotypes of GSTM1 and GSTT1 contribute to hepatocellular carcinoma risk: evidence from an updated metaanalysis
    • PMID: 20561699
    • Wang B, Huang G, Wang D, Li A, Xu Z, Dong R, Zhang D, Zhou W. Null genotypes of GSTM1 and GSTT1 contribute to hepatocellular carcinoma risk: evidence from an updated metaanalysis. J Hepatol 2010; 53: 508-518 [PMID: 20561699 DOI: 10.1016/j.jhep.2010.03.026]
    • (2010) J Hepatol , vol.53 , pp. 508-518
    • Wang, B.1    Huang, G.2    Wang, D.3    Li, A.4    Xu, Z.5    Dong, R.6    Zhang, D.7    Zhou, W.8
  • 84
    • 77950200986 scopus 로고    scopus 로고
    • Association between C282Y and H63D mutations of the HFE gene with hepatocellular carcinoma in European populations: a meta-analysis
    • PMID: 20196837
    • Jin F, Qu LS, Shen XZ. Association between C282Y and H63D mutations of the HFE gene with hepatocellular carcinoma in European populations: a meta-analysis. J Exp Clin Cancer Res 2010; 29: 18 [PMID: 20196837 DOI: 10.1186/1756-9966-29-18]
    • (2010) J Exp Clin Cancer Res , vol.29 , pp. 18
    • Jin, F.1    Qu, L.S.2    Shen, X.Z.3
  • 92
    • 77349092851 scopus 로고    scopus 로고
    • Molecular classification and novel targets in hepatocellular carcinoma: recent advancements
    • PMID: 20175032
    • Hoshida Y, Toffanin S, Lachenmayer A, Villanueva A, Minguez B, Llovet JM. Molecular classification and novel targets in hepatocellular carcinoma: recent advancements. Semin Liver Dis 2010; 30: 35-51 [PMID: 20175032 DOI: 10.1055/s-0030-1247131]
    • (2010) Semin Liver Dis , vol.30 , pp. 35-51
    • Hoshida, Y.1    Toffanin, S.2    Lachenmayer, A.3    Villanueva, A.4    Minguez, B.5    Llovet, J.M.6
  • 93
    • 33847069207 scopus 로고    scopus 로고
    • Genomics and signaling pathways in hepatocellular carcinoma
    • PMID: 17295177
    • Villanueva A, Newell P, Chiang DY, Friedman SL, Llovet JM. Genomics and signaling pathways in hepatocellular carcinoma. Semin Liver Dis 2007; 27: 55-76 [PMID: 17295177 DOI: 10.1055/s-2006-960171]
    • (2007) Semin Liver Dis , vol.27 , pp. 55-76
    • Villanueva, A.1    Newell, P.2    Chiang, D.Y.3    Friedman, S.L.4    Llovet, J.M.5
  • 94
    • 84864455290 scopus 로고    scopus 로고
    • Gene signatures in the management of hepatocellular carcinoma
    • PMID: 22846864
    • Hoshida Y, Moeini A, Alsinet C, Kojima K, Villanueva A. Gene signatures in the management of hepatocellular carcinoma. Semin Oncol 2012; 39: 473-485 [PMID: 22846864 DOI: 10.1053/j.semin oncol.2012.05.003]
    • (2012) Semin Oncol , vol.39 , pp. 473-485
    • Hoshida, Y.1    Moeini, A.2    Alsinet, C.3    Kojima, K.4    Villanueva, A.5
  • 97
    • 84929286812 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β is associated with the prognosis of hepatocellular carcinoma and may mediate the influence of type 2 diabetes mellitus on hepatocellular carcinoma
    • PMID: 25157753
    • Qiao G, Le Y, Li J, Wang L, Shen F. Glycogen synthase kinase-3β is associated with the prognosis of hepatocellular carcinoma and may mediate the influence of type 2 diabetes mellitus on hepatocellular carcinoma. PLoS One 2014; 9: e105624 [PMID: 25157753 DOI: 10.1371/journal.pone.0105624]
    • (2014) PLoS One , vol.9
    • Qiao, G.1    Le, Y.2    Li, J.3    Wang, L.4    Shen, F.5
  • 98
    • 84949967185 scopus 로고    scopus 로고
    • Hepatocellular Carcinoma Arising in an HNF-1a-Mutated Adenoma in a 23-Year-Old Woman with Maturity-Onset Diabetes of the Young: A Case Report
    • PMID: 26676820
    • Stueck AE, Qu Z, Huang MA, Campreciós G, Ferrell LD, Thung SN. Hepatocellular Carcinoma Arising in an HNF-1a-Mutated Adenoma in a 23-Year-Old Woman with Maturity-Onset Diabetes of the Young: A Case Report. Semin Liver Dis 2015; 35: 444-449 [PMID: 26676820 DOI: 10.1055/s-0035-1567827]
    • (2015) Semin Liver Dis , vol.35 , pp. 444-449
    • Stueck, A.E.1    Qu, Z.2    Huang, M.A.3    Campreciós, G.4    Ferrell, L.D.5    Thung, S.N.6
  • 99
    • 84908118422 scopus 로고    scopus 로고
    • Insight into the impact of diabetes mellitus on the increased risk of hepatocellular carcinoma: mini-review
    • PMID: 24918094
    • Ali Kamkar MM, Ahmad R, Alsmadi O, Behbehani K. Insight into the impact of diabetes mellitus on the increased risk of hepatocellular carcinoma: mini-review. J Diabetes Metab Disord 2014; 13: 57 [PMID: 24918094 DOI: 10.1186/2251-6581-13-57]
    • (2014) J Diabetes Metab Disord , vol.13 , pp. 57
    • Ali Kamkar, M.M.1    Ahmad, R.2    Alsmadi, O.3    Behbehani, K.4
  • 100
    • 84882743053 scopus 로고    scopus 로고
    • The influence of diabetes in the pathogenesis and the clinical course of hepatocellular carcinoma: recent findings and new perspectives
    • PMID: 23845075
    • Facciorusso A. The influence of diabetes in the pathogenesis and the clinical course of hepatocellular carcinoma: recent findings and new perspectives. Curr Diabetes Rev 2013; 9: 382-386 [PMID: 23845075]
    • (2013) Curr Diabetes Rev , vol.9 , pp. 382-386
    • Facciorusso, A.1


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