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Volumn 13, Issue 1, 2016, Pages

Precision medicine: From pharmacogenomics to pharmacoproteomics

Author keywords

Biomarker; Pharmacogenomics; Precision medicine; Proteomics

Indexed keywords

CLOPIDOGREL; DASATINIB; EVEROLIMUS; FLUOROURACIL; OXALIPLATIN; PAZOPANIB; SIMVASTATIN; TAMOXIFEN;

EID: 84992213777     PISSN: 15426416     EISSN: 15590275     Source Type: Journal    
DOI: 10.1186/s12014-016-9127-8     Document Type: Review
Times cited : (36)

References (87)
  • 1
    • 84992211212 scopus 로고    scopus 로고
    • Senate panel approves $2 billion raise for NIH in 2016
    • 10.1126/science.aac6887
    • Kaiser J. Senate panel approves $2 billion raise for NIH in 2016. Sci Mag. 2015. doi: 10.1126/science.aac6887.
    • (2015) Sci Mag
    • Kaiser, J.1
  • 2
    • 84923762812 scopus 로고    scopus 로고
    • A new initiative on precision medicine
    • 1:CAS:528:DC%2BC2MXjvFGnsLY%3D 25635347
    • Collins FS, Varmus H. A new initiative on precision medicine. N Engl J Med. 2015;372:793-5.
    • (2015) N Engl J Med , vol.372 , pp. 793-795
    • Collins, F.S.1    Varmus, H.2
  • 3
    • 0037115525 scopus 로고    scopus 로고
    • Pharmacogenetics affects dosing, efficacy, and toxicity of cytochrome P450-metabolized drugs
    • 1:CAS:528:DC%2BD3sXotVWm 12517365
    • Rogers JF, Nafziger AN, Bertino JS Jr. Pharmacogenetics affects dosing, efficacy, and toxicity of cytochrome P450-metabolized drugs. Am J Med. 2002;113:746-50.
    • (2002) Am J Med , vol.113 , pp. 746-750
    • Rogers, J.F.1    Nafziger, A.N.2    Bertino, J.S.3
  • 4
    • 2642570170 scopus 로고    scopus 로고
    • Moving towards individualized medicine with pharmacogenomics
    • 1:CAS:528:DC%2BD2cXkt1Onsbo%3D 15164072
    • Evans WE, Relling MV. Moving towards individualized medicine with pharmacogenomics. Nature. 2004;429:464-8.
    • (2004) Nature , vol.429 , pp. 464-468
    • Evans, W.E.1    Relling, M.V.2
  • 5
    • 13144265739 scopus 로고    scopus 로고
    • Genome-wide association studies: Theoretical and practical concerns
    • 1:CAS:528:DC%2BD2MXhtFyjsrw%3D 15716907
    • Wang WY, Barratt BJ, Clayton DG, Todd JA. Genome-wide association studies: theoretical and practical concerns. Nat Rev Genet. 2005;6:109-18.
    • (2005) Nat Rev Genet , vol.6 , pp. 109-118
    • Wang, W.Y.1    Barratt, B.J.2    Clayton, D.G.3    Todd, J.A.4
  • 7
    • 18744369628 scopus 로고    scopus 로고
    • Pharmacogenomics and the drug discovery pipeline: When should it be implemented?
    • 1:CAS:528:DC%2BD2MXjtVOlsbw%3D 15727489
    • Penny MA, McHale D. Pharmacogenomics and the drug discovery pipeline: when should it be implemented? Am J Pharmacogenomics. 2005;5:53-62.
    • (2005) Am J Pharmacogenomics , vol.5 , pp. 53-62
    • Penny, M.A.1    McHale, D.2
  • 8
    • 83755207567 scopus 로고    scopus 로고
    • Lymphoblastoid cell lines in pharmacogenomic discovery and clinical translation
    • 1:CAS:528:DC%2BC3MXhs1CitLbM 22176622 3292907
    • Wheeler HE, Dolan ME. Lymphoblastoid cell lines in pharmacogenomic discovery and clinical translation. Pharmacogenomics. 2012;13:55-70.
    • (2012) Pharmacogenomics , vol.13 , pp. 55-70
    • Wheeler, H.E.1    Dolan, M.E.2
  • 9
    • 84923698780 scopus 로고    scopus 로고
    • In vitro human cell line models to predict clinical response to anticancer drugs
    • 1:CAS:528:DC%2BC2MXjtlSmsb8%3D 25712190 4358765
    • Niu N, Wang L. In vitro human cell line models to predict clinical response to anticancer drugs. Pharmacogenomics. 2015;16:273-85.
    • (2015) Pharmacogenomics , vol.16 , pp. 273-285
    • Niu, N.1    Wang, L.2
  • 10
    • 49949104757 scopus 로고    scopus 로고
    • SLCO1B1 variants and statin-induced myopathy - A genomewide study
    • Search Collaborative Group
    • Search Collaborative Group. SLCO1B1 variants and statin-induced myopathy - a genomewide study. N Engl J Med. 2008;359:789-99.
    • (2008) N Engl J Med , vol.359 , pp. 789-799
  • 11
    • 84989804925 scopus 로고    scopus 로고
    • Genetically guided statin therapy on statin perceptions, adherence, and cholesterol lowering: A pilot implementation study in primary care patients
    • 25563221 4263970
    • Li JH, Joy SV, Haga SB, Orlando LA, Kraus WE, Ginsburg GS, Voora D. Genetically guided statin therapy on statin perceptions, adherence, and cholesterol lowering: a pilot implementation study in primary care patients. J Pers Med. 2014;4:147-62.
    • (2014) J Pers Med , vol.4 , pp. 147-162
    • Li, J.H.1    Joy, S.V.2    Haga, S.B.3    Orlando, L.A.4    Kraus, W.E.5    Ginsburg, G.S.6    Voora, D.7
  • 13
    • 84878866053 scopus 로고    scopus 로고
    • Pharmacogenomics of lipid-lowering therapies
    • 1:CAS:528:DC%2BC3sXptVWnsbs%3D 23746191
    • Hu M, Tomlinson B. Pharmacogenomics of lipid-lowering therapies. Pharmacogenomics. 2013;14:981-95.
    • (2013) Pharmacogenomics , vol.14 , pp. 981-995
    • Hu, M.1    Tomlinson, B.2
  • 15
    • 84904907494 scopus 로고    scopus 로고
    • Citalopram and escitalopram plasma drug and metabolite concentrations: Genome-wide associations
    • 1:CAS:528:DC%2BC2cXht1SmtL%2FJ 24528284 4137829
    • Ji Y, Schaid DJ, Desta Z, Kubo M, Batzler AJ, Snyder K, et al. Citalopram and escitalopram plasma drug and metabolite concentrations: genome-wide associations. Br J Clin Pharmacol. 2014;78:373-83.
    • (2014) Br J Clin Pharmacol , vol.78 , pp. 373-383
    • Ji, Y.1    Schaid, D.J.2    Desta, Z.3    Kubo, M.4    Batzler, A.J.5    Snyder, K.6
  • 16
    • 84929084053 scopus 로고    scopus 로고
    • Genome-wide association studies in pharmacogenomics of antidepressants
    • 1:CAS:528:DC%2BC2MXntFegt7k%3D 25916525
    • Lin E, Lane HY. Genome-wide association studies in pharmacogenomics of antidepressants. Pharmacogenomics. 2015;16:555-66.
    • (2015) Pharmacogenomics , vol.16 , pp. 555-566
    • Lin, E.1    Lane, H.Y.2
  • 18
    • 84875485693 scopus 로고    scopus 로고
    • Cancer pharmacogenomics: Early promise, but concerted effort needed
    • 1:CAS:528:DC%2BC3sXksFOhsbs%3D 23539596 3900028
    • McLeod HL. Cancer pharmacogenomics: early promise, but concerted effort needed. Science. 2013;339:1563-6.
    • (2013) Science , vol.339 , pp. 1563-1566
    • McLeod, H.L.1
  • 19
    • 36349024762 scopus 로고    scopus 로고
    • Breast cancer treatment outcome with adjuvant tamoxifen relative to patient CYP2D6 and CYP2C19 genotypes
    • 1:CAS:528:DC%2BD2sXhsVKnsbzN 18024866
    • Schroth W, Antoniadou L, Fritz P, Schwab M, Muerdter T, Zanger UM, et al. Breast cancer treatment outcome with adjuvant tamoxifen relative to patient CYP2D6 and CYP2C19 genotypes. J Clin Oncol. 2007;25:5187-93.
    • (2007) J Clin Oncol , vol.25 , pp. 5187-5193
    • Schroth, W.1    Antoniadou, L.2    Fritz, P.3    Schwab, M.4    Muerdter, T.5    Zanger, U.M.6
  • 21
    • 84905817082 scopus 로고    scopus 로고
    • Dose-finding and pharmacokinetic study to optimize the dosing of irinotecan according to the UGT1A1 genotype of patients with cancer
    • 1:CAS:528:DC%2BC2cXhslCisrnJ 24958824 4105486
    • Innocenti F, Schilsky RL, Ramirez J, Janisch L, Undevia S, House LK, et al. Dose-finding and pharmacokinetic study to optimize the dosing of irinotecan according to the UGT1A1 genotype of patients with cancer. J Clin Oncol. 2014;32:2328-34.
    • (2014) J Clin Oncol , vol.32 , pp. 2328-2334
    • Innocenti, F.1    Schilsky, R.L.2    Ramirez, J.3    Janisch, L.4    Undevia, S.5    House, L.K.6
  • 22
    • 84897861518 scopus 로고    scopus 로고
    • Prediction of tamoxifen outcome by genetic variation of CYP2D6 in post-menopausal women with early breast cancer
    • 1:CAS:528:DC%2BC2cXkvVCqtrs%3D 24033728 3971985
    • Brauch H, Schwab M. Prediction of tamoxifen outcome by genetic variation of CYP2D6 in post-menopausal women with early breast cancer. Br J Clin Pharmacol. 2014;77:695-703.
    • (2014) Br J Clin Pharmacol , vol.77 , pp. 695-703
    • Brauch, H.1    Schwab, M.2
  • 23
    • 79951809825 scopus 로고    scopus 로고
    • CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network
    • 1:STN:280:DC%2BC3M7ps1WhtA%3D%3D 21270786 3098762
    • Relling MV, Klein TE. CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network. Clin Pharmacol Ther. 2011;89:464-7.
    • (2011) Clin Pharmacol Ther , vol.89 , pp. 464-467
    • Relling, M.V.1    Klein, T.E.2
  • 24
    • 84878247061 scopus 로고    scopus 로고
    • Pharmacogenomics in colorectal cancer: A genome-wide association study to predict toxicity after 5-fluorouracil or FOLFOX administration
    • 1:CAS:528:DC%2BC38XhvVGntr0%3D 22310351
    • Fernandez-Rozadilla C, Cazier JB, Moreno V, Crous-Bou M, Guino E, Duran G, et al. Pharmacogenomics in colorectal cancer: a genome-wide association study to predict toxicity after 5-fluorouracil or FOLFOX administration. Pharmacogenomics J. 2013;13:209-17.
    • (2013) Pharmacogenomics J , vol.13 , pp. 209-217
    • Fernandez-Rozadilla, C.1    Cazier, J.B.2    Moreno, V.3    Crous-Bou, M.4    Guino, E.5    Duran, G.6
  • 25
    • 84956843096 scopus 로고    scopus 로고
    • Genome-wide association study of myelosuppression in non-small-cell lung cancer patients with platinum-based chemotherapy
    • 1:CAS:528:DC%2BC2MXlsFekurc%3D 25823687
    • Cao S, Wang S, Ma H, Tang S, Sun C, Dai J, et al. Genome-wide association study of myelosuppression in non-small-cell lung cancer patients with platinum-based chemotherapy. Pharmacogenomics J. 2016;16:41-6.
    • (2016) Pharmacogenomics J , vol.16 , pp. 41-46
    • Cao, S.1    Wang, S.2    Ma, H.3    Tang, S.4    Sun, C.5    Dai, J.6
  • 26
    • 84895854130 scopus 로고    scopus 로고
    • The epigenetic basis of common human disease
    • 23874013 3715917
    • Feinberg AP. The epigenetic basis of common human disease. Trans Am Clin Climatol Assoc. 2013;124:84-93.
    • (2013) Trans Am Clin Climatol Assoc , vol.124 , pp. 84-93
    • Feinberg, A.P.1
  • 27
    • 84924008674 scopus 로고    scopus 로고
    • The second coming of epigenetic drugs: A more strategic and broader research framework could boost the development of new drugs to modify epigenetic factors and gene expression
    • 1:CAS:528:DC%2BC2MXjs1Gntbw%3D 25662153 4364867
    • Hunter P. The second coming of epigenetic drugs: a more strategic and broader research framework could boost the development of new drugs to modify epigenetic factors and gene expression. EMBO Rep. 2015;16:276-9.
    • (2015) EMBO Rep , vol.16 , pp. 276-279
    • Hunter, P.1
  • 28
    • 84912139590 scopus 로고    scopus 로고
    • DNA methylation and personalized medicine
    • 1:CAS:528:DC%2BC2cXhsl2hsbrL 25230364
    • Tang J, Xiong Y, Zhou HH, Chen XP. DNA methylation and personalized medicine. J Clin Pharm Ther. 2014;39:621-7.
    • (2014) J Clin Pharm Ther , vol.39 , pp. 621-627
    • Tang, J.1    Xiong, Y.2    Zhou, H.H.3    Chen, X.P.4
  • 29
    • 38949094492 scopus 로고    scopus 로고
    • Cytochrome p450 and chemical toxicology
    • 1:CAS:528:DC%2BD2sXhtlynurbF 18052394
    • Guengerich FP. Cytochrome p450 and chemical toxicology. Chem Res Toxicol. 2008;21:70-83.
    • (2008) Chem Res Toxicol , vol.21 , pp. 70-83
    • Guengerich, F.P.1
  • 30
    • 54949144309 scopus 로고    scopus 로고
    • Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation
    • 1:CAS:528:DC%2BD1cXht1yqsbjP 18695978
    • Zanger UM, Turpeinen M, Klein K, Schwab M. Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation. Anal Bioanal Chem. 2008;392:1093-108.
    • (2008) Anal Bioanal Chem , vol.392 , pp. 1093-1108
    • Zanger, U.M.1    Turpeinen, M.2    Klein, K.3    Schwab, M.4
  • 31
    • 84975709046 scopus 로고    scopus 로고
    • DNA methylation of ADME genes
    • 1:CAS:528:DC%2BC28XlslWhtrk%3D 27061006
    • Fisel P, Schaeffeler E, Schwab M. DNA methylation of ADME genes. Clin Pharmacol Ther. 2016;99:512-27.
    • (2016) Clin Pharmacol Ther , vol.99 , pp. 512-527
    • Fisel, P.1    Schaeffeler, E.2    Schwab, M.3
  • 32
    • 84979649916 scopus 로고    scopus 로고
    • A landscape of pharmacogenomic interactions in cancer
    • 10.1016/j.cell.2016.06.017 1:CAS:528:DC%2BC28XhtFCiu73L 27397505 4967469
    • Iorio F, Knijnenburg TA, Vis DJ, Bignell GR, Menden MP, Schubert M, et al. A landscape of pharmacogenomic interactions in cancer. Cell. 2016;166(3):740-54. doi: 10.1016/j.cell.2016.06.017.
    • (2016) Cell. , vol.166 , Issue.3 , pp. 740-754
    • Iorio, F.1    Knijnenburg, T.A.2    Vis, D.J.3    Bignell, G.R.4    Menden, M.P.5    Schubert, M.6
  • 34
    • 84877768701 scopus 로고    scopus 로고
    • First pharmacogenomic analysis using whole exome sequencing to identify novel genetic determinants of clopidogrel response variability: Results of the genotype information and functional testing (GIFT) exome study
    • 10.1016/S0735-1097(12)60010-2
    • Price MJ, Carson AR, Murray SS, Phillips T, Janel L, Tisch R, et al. First pharmacogenomic analysis using whole exome sequencing to identify novel genetic determinants of clopidogrel response variability: results of the genotype information and functional testing (GIFT) exome study. J Am Coll Cardiol. 2012;59(13s1):E9. doi: 10.1016/S0735-1097(12)60010-2.
    • (2012) J Am Coll Cardiol , vol.59 , Issue.13 S1 , pp. E9
    • Price, M.J.1    Carson, A.R.2    Murray, S.S.3    Phillips, T.4    Janel, L.5    Tisch, R.6
  • 35
    • 84899680978 scopus 로고    scopus 로고
    • Activating mTOR mutations in a patient with an extraordinary response on a phase i trial of everolimus and pazopanib
    • 24625776 4122326
    • Wagle N, Grabiner BC, Van Allen EM, Hodis E, Jacobus S, Supko JG, Stewart M, et al. Activating mTOR mutations in a patient with an extraordinary response on a phase I trial of everolimus and pazopanib. Cancer Discov. 2014;4:546-53.
    • (2014) Cancer Discov , vol.4 , pp. 546-553
    • Wagle, N.1    Grabiner, B.C.2    Van Allen, E.M.3    Hodis, E.4    Jacobus, S.5    Supko, J.G.6    Stewart, M.7
  • 36
    • 84944311937 scopus 로고    scopus 로고
    • Pharmacogenomics in the clinic
    • 1:CAS:528:DC%2BC2MXhs1KqtL%2FJ 26469045 4711261
    • Relling MV, Evans WE. Pharmacogenomics in the clinic. Nature. 2015;526:343-50.
    • (2015) Nature , vol.526 , pp. 343-350
    • Relling, M.V.1    Evans, W.E.2
  • 37
    • 77956261738 scopus 로고    scopus 로고
    • Sequence signatures and mRNA concentration can explain two-thirds of protein abundance variation in a human cell line
    • 20739923 2947365
    • Vogel C, Abreu Rde S, Ko D, Le SY, Shapiro BA, Burns SC, et al. Sequence signatures and mRNA concentration can explain two-thirds of protein abundance variation in a human cell line. Mol Syst Biol. 2010;6:400.
    • (2010) Mol Syst Biol , vol.6 , pp. 400
    • Vogel, C.1    Abreu Rde, S.2    Ko, D.3    Le, S.Y.4    Shapiro, B.A.5    Burns, S.C.6
  • 38
    • 84911444179 scopus 로고    scopus 로고
    • Multiple evidence strands suggest that there may be as few as 19,000 human protein-coding genes
    • 1:CAS:528:DC%2BC28XhtFKqsLnM 24939910 4204768
    • Ezkurdia I, Juan D, Rodriguez JM, Frankish A, Diekhans M, Harrow J, et al. Multiple evidence strands suggest that there may be as few as 19,000 human protein-coding genes. Hum Mol Genet. 2014;23:5866-78.
    • (2014) Hum Mol Genet , vol.23 , pp. 5866-5878
    • Ezkurdia, I.1    Juan, D.2    Rodriguez, J.M.3    Frankish, A.4    Diekhans, M.5    Harrow, J.6
  • 39
    • 9244226956 scopus 로고    scopus 로고
    • Role of pharmacoproteomics in the development of personalized medicine
    • 1:STN:280:DC%2BD2c3gs1ehsA%3D%3D 15102547
    • Jain KK. Role of pharmacoproteomics in the development of personalized medicine. Pharmacogenomics. 2004;5:331-6.
    • (2004) Pharmacogenomics , vol.5 , pp. 331-336
    • Jain, K.K.1
  • 40
    • 57749195712 scopus 로고    scopus 로고
    • RNA-Seq: A revolutionary tool for transcriptomics
    • 1:CAS:528:DC%2BD1cXhsFWis7bL 19015660 2949280
    • Wang Z, Gerstein M, Snyder M. RNA-Seq: a revolutionary tool for transcriptomics. Nat Rev Genet. 2009;10(1):57-63.
    • (2009) Nat Rev Genet , vol.10 , Issue.1 , pp. 57-63
    • Wang, Z.1    Gerstein, M.2    Snyder, M.3
  • 41
    • 84874854709 scopus 로고    scopus 로고
    • Integrated analysis of transcriptomic and proteomic data
    • 1:CAS:528:DC%2BC3sXlslGrt7k%3D
    • Haider S, Pal R. Integrated analysis of transcriptomic and proteomic data. Curr Genom. 2013;14(2):91-110.
    • (2013) Curr Genom , vol.14 , Issue.2 , pp. 91-110
    • Haider, S.1    Pal, R.2
  • 42
    • 4544306096 scopus 로고    scopus 로고
    • Pharmacoproteomic approach to the study of drug mode of action, toxicity, and resistance: Applications in diabetes and cancer
    • 1:CAS:528:DC%2BD2cXnvVWmtLs%3D 15312147
    • Chapal N, Molina L, Molina F, Laplanche M, Pau B, Petit P. Pharmacoproteomic approach to the study of drug mode of action, toxicity, and resistance: applications in diabetes and cancer. Fundam Clin Pharmacol. 2004;18:413-22.
    • (2004) Fundam Clin Pharmacol , vol.18 , pp. 413-422
    • Chapal, N.1    Molina, L.2    Molina, F.3    Laplanche, M.4    Pau, B.5    Petit, P.6
  • 43
    • 0038312125 scopus 로고    scopus 로고
    • Pharmacoproteomics in drug development
    • 1:CAS:528:DC%2BD3sXjs1Kgu78%3D 12746732
    • Witzmann FA, Grant RA. Pharmacoproteomics in drug development. Pharmacogenomics J. 2003;3:69-76.
    • (2003) Pharmacogenomics J , vol.3 , pp. 69-76
    • Witzmann, F.A.1    Grant, R.A.2
  • 44
    • 0036020645 scopus 로고    scopus 로고
    • Pharmacogenomics/pharmacoproteomics Europe
    • 12164769
    • Meister W. Pharmacogenomics/pharmacoproteomics Europe. Pharmacogenomics. 2002;3:449-52.
    • (2002) Pharmacogenomics , vol.3 , pp. 449-452
    • Meister, W.1
  • 45
  • 46
    • 77955983759 scopus 로고    scopus 로고
    • Activity-based protein profiling for biochemical pathway discovery in cancer
    • 1:CAS:528:DC%2BC3cXhtVSmu7rM 20703252 3021511
    • Nomura DK, Dix MM, Cravatt BF. Activity-based protein profiling for biochemical pathway discovery in cancer. Nat Rev Cancer. 2010;10:630-8.
    • (2010) Nat Rev Cancer , vol.10 , pp. 630-638
    • Nomura, D.K.1    Dix, M.M.2    Cravatt, B.F.3
  • 47
    • 69249136243 scopus 로고    scopus 로고
    • Target profiling of small molecules by chemical proteomics
    • 1:CAS:528:DC%2BD1MXhtVWhsb7K 19690537
    • Rix U, Superti-Furga G. Target profiling of small molecules by chemical proteomics. Nat Chem Biol. 2009;5:616-24.
    • (2009) Nat Chem Biol , vol.5 , pp. 616-624
    • Rix, U.1    Superti-Furga, G.2
  • 48
    • 84904415791 scopus 로고    scopus 로고
    • Current developments in activity-based protein profiling
    • 1:CAS:528:DC%2BC2cXhtVSmu7vN 24946272
    • Willems LI, Overkleeft HS, van Kasteren SI. Current developments in activity-based protein profiling. Bioconjug Chem. 2014;25:1181-91.
    • (2014) Bioconjug Chem , vol.25 , pp. 1181-1191
    • Willems, L.I.1    Overkleeft, H.S.2    Van Kasteren, S.I.3
  • 49
    • 0036583926 scopus 로고    scopus 로고
    • Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics
    • 1:CAS:528:DC%2BD38XlslWhsrk%3D
    • Ong SE, Blagoev B, Kratchmarova I, Kristensen DB, Steen H, Pandey A, Mann M. Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol Cell Proteom. 2002;1:376-86.
    • (2002) Mol Cell Proteom , vol.1 , pp. 376-386
    • Ong, S.E.1    Blagoev, B.2    Kratchmarova, I.3    Kristensen, D.B.4    Steen, H.5    Pandey, A.6    Mann, M.7
  • 52
    • 84894329528 scopus 로고    scopus 로고
    • Mass spectrometry in cancer biomarker research: A case for immunodepletion of abundant blood-derived proteins from clinical tissue specimens
    • 1:CAS:528:DC%2BC2cXisVahs7k%3D 24521024 4201940
    • Prieto DA, Johann DJ Jr, Wei BR, Ye X, Chan KC, Nissley DV, et al. Mass spectrometry in cancer biomarker research: a case for immunodepletion of abundant blood-derived proteins from clinical tissue specimens. Biomark Med. 2014;8:269-86.
    • (2014) Biomark Med , vol.8 , pp. 269-286
    • Prieto, D.A.1    Johann, D.J.2    Wei, B.R.3    Ye, X.4    Chan, K.C.5    Nissley, D.V.6
  • 53
    • 84865802221 scopus 로고    scopus 로고
    • Phosphosignature predicts dasatinib response in non-small cell lung cancer
    • 1:CAS:528:DC%2BC38XhtlOjsL%2FF
    • Klammer M, Kaminski M, Zedler A, Oppermann F, Blencke S, Marx S, et al. Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteom. 2012;11:651-68.
    • (2012) Mol Cell Proteom , vol.11 , pp. 651-668
    • Klammer, M.1    Kaminski, M.2    Zedler, A.3    Oppermann, F.4    Blencke, S.5    Marx, S.6
  • 54
    • 33645463194 scopus 로고    scopus 로고
    • Multiplexed protein measurement: Technologies and applications of protein and antibody arrays
    • 1:CAS:528:DC%2BD28XjtVaksr8%3D 16582876 1780251
    • Kingsmore SF. Multiplexed protein measurement: technologies and applications of protein and antibody arrays. Nat Rev Drug Discov. 2006;5(4):310-20.
    • (2006) Nat Rev Drug Discov , vol.5 , Issue.4 , pp. 310-320
    • Kingsmore, S.F.1
  • 55
    • 63849172494 scopus 로고    scopus 로고
    • Identifying the proteins to which small-molecule probes and drugs bind in cells
    • 1:CAS:528:DC%2BD1MXktFOgsb4%3D 19255428 2649954
    • Ong SE, Schenone M, Margolin AA, Li X, Do K, Doud MK, et al. Identifying the proteins to which small-molecule probes and drugs bind in cells. Proc Natl Acad Sci U S A. 2009;106:4617-22.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 4617-4622
    • Ong, S.E.1    Schenone, M.2    Margolin, A.A.3    Li, X.4    Do, K.5    Doud, M.K.6
  • 56
    • 84901950348 scopus 로고    scopus 로고
    • Quantitative chemical proteomics identifies novel targets of the anti-cancer multi-kinase inhibitor E-3810
    • 1:CAS:528:DC%2BC2cXpsFCjtrY%3D
    • Colzani M, Noberini R, Romanenghi M, Colella G, Pasi M, Fancelli D, et al. Quantitative chemical proteomics identifies novel targets of the anti-cancer multi-kinase inhibitor E-3810. Mol Cell Proteom. 2014;13:1495-509.
    • (2014) Mol Cell Proteom , vol.13 , pp. 1495-1509
    • Colzani, M.1    Noberini, R.2    Romanenghi, M.3    Colella, G.4    Pasi, M.5    Fancelli, D.6
  • 57
    • 84892576029 scopus 로고    scopus 로고
    • Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells
    • 24292625
    • Kronke J, Udeshi ND, Narla A, Grauman P, Hurst SN, McConkey M, et al. Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells. Science. 2014;343:301-5.
    • (2014) Science , vol.343 , pp. 301-305
    • Kronke, J.1    Udeshi, N.D.2    Narla, A.3    Grauman, P.4    Hurst, S.N.5    McConkey, M.6
  • 58
    • 79960427057 scopus 로고    scopus 로고
    • Selective killing of cancer cells by a small molecule targeting the stress response to ROS
    • 1:CAS:528:DC%2BC3MXovFegt7Y%3D 21753854 3316487
    • Raj L, Ide T, Gurkar AU, Foley M, Schenone M, Li X, et al. Selective killing of cancer cells by a small molecule targeting the stress response to ROS. Nature. 2011;475:231-4.
    • (2011) Nature , vol.475 , pp. 231-234
    • Raj, L.1    Ide, T.2    Gurkar, A.U.3    Foley, M.4    Schenone, M.5    Li, X.6
  • 59
    • 84856402803 scopus 로고    scopus 로고
    • How chemoproteomics can enable drug discovery and development
    • 1:CAS:528:DC%2BC38Xhs1GjtLk%3D 22284350 3312051
    • Moellering RE, Cravatt BF. How chemoproteomics can enable drug discovery and development. Chem Biol. 2012;19:11-22.
    • (2012) Chem Biol , vol.19 , pp. 11-22
    • Moellering, R.E.1    Cravatt, B.F.2
  • 60
    • 84948822926 scopus 로고    scopus 로고
    • Pharmacoproteomics identifies combinatorial therapy targets for diffuse large B cell lymphoma
    • 26529251 4665772
    • Goldstein RL, Yang SN, Taldone T, Chang B, Gerecitano J, Elenitoba-Johnson K, et al. Pharmacoproteomics identifies combinatorial therapy targets for diffuse large B cell lymphoma. J Clin Invest. 2015;125:4559-71.
    • (2015) J Clin Invest , vol.125 , pp. 4559-4571
    • Goldstein, R.L.1    Yang, S.N.2    Taldone, T.3    Chang, B.4    Gerecitano, J.5    Elenitoba-Johnson, K.6
  • 61
    • 84878273363 scopus 로고    scopus 로고
    • Pharmaco-proteomics opportunities for individualizing neurovascular treatment
    • 1:CAS:528:DC%2BC3sXosFOjtbg%3D 23711324 4153693
    • Ning MM, Lopez M, Sarracino D, Cao J, Karchin M, McMullin D, et al. Pharmaco-proteomics opportunities for individualizing neurovascular treatment. Neurol Res. 2013;35:448-56.
    • (2013) Neurol Res , vol.35 , pp. 448-456
    • Ning, M.M.1    Lopez, M.2    Sarracino, D.3    Cao, J.4    Karchin, M.5    McMullin, D.6
  • 62
    • 84901056306 scopus 로고    scopus 로고
    • Quantitative targeted proteomics for understanding the blood-brain barrier: Towards pharmacoproteomics
    • 1:CAS:528:DC%2BC2cXotVektbg%3D
    • Ohtsuki S, Hirayama M, Ito S, Uchida Y, Tachikawa M, Terasaki T. Quantitative targeted proteomics for understanding the blood-brain barrier: towards pharmacoproteomics. Expert Rev Proteom. 2014;11:303-13.
    • (2014) Expert Rev Proteom , vol.11 , pp. 303-313
    • Ohtsuki, S.1    Hirayama, M.2    Ito, S.3    Uchida, Y.4    Tachikawa, M.5    Terasaki, T.6
  • 63
    • 8544277251 scopus 로고    scopus 로고
    • Toxicoproteomics: Proteomics applied to toxicology and pathology
    • 1:CAS:528:DC%2BD2cXnvV2qtbY%3D 15580702
    • Wetmore BA, Merrick BA. Toxicoproteomics: proteomics applied to toxicology and pathology. Toxicol Pathol. 2004;32:619-42.
    • (2004) Toxicol Pathol , vol.32 , pp. 619-642
    • Wetmore, B.A.1    Merrick, B.A.2
  • 64
    • 84924598514 scopus 로고    scopus 로고
    • Proteomics in mechanistic toxicology: History, concepts, achievements, caveats, and potential
    • 1:CAS:528:DC%2BC2MXlslentLs%3D 25164579
    • Rabilloud T, Lescuyer P. Proteomics in mechanistic toxicology: history, concepts, achievements, caveats, and potential. Proteomics. 2015;15:1051-74.
    • (2015) Proteomics , vol.15 , pp. 1051-1074
    • Rabilloud, T.1    Lescuyer, P.2
  • 66
    • 84893763297 scopus 로고    scopus 로고
    • Pharmacometabolomics: Implications for clinical pharmacology and systems pharmacology
    • Pharmacometabolomics Research N 1:CAS:528:DC%2BC2cXmtlSnug%3D%3D 24193171
    • Kaddurah-Daouk R, Weinshilboum RM, Pharmacometabolomics Research N. Pharmacometabolomics: implications for clinical pharmacology and systems pharmacology. Clin Pharmacol Ther. 2014;95:154-67.
    • (2014) Clin Pharmacol Ther , vol.95 , pp. 154-167
    • Kaddurah-Daouk, R.1    Weinshilboum, R.M.2
  • 67
    • 84959344007 scopus 로고    scopus 로고
    • Temporal characterization of serum metabolite signatures in lung cancer patients undergoing treatment
    • 27073350 4819600
    • Hao D, Sarfaraz MO, Farshidfar F, Bebb DG, Lee CY, Card CM, et al. Temporal characterization of serum metabolite signatures in lung cancer patients undergoing treatment. Metabolomics. 2016;12:58.
    • (2016) Metabolomics , vol.12 , pp. 58
    • Hao, D.1    Sarfaraz, M.O.2    Farshidfar, F.3    Bebb, D.G.4    Lee, C.Y.5    Card, C.M.6
  • 68
    • 84982920561 scopus 로고    scopus 로고
    • Phamacometabolomics study identifies circulating spermidine and tryptophan as potential biomarkers associated with the complete pathological response to trastuzumab-paclitaxel neoadjuvant therapy in HER-2 positive breast cancer
    • Miolo G, Muraro E, Caruso D, Crivellari D, Ash A, Scalone S, et al. Phamacometabolomics study identifies circulating spermidine and tryptophan as potential biomarkers associated with the complete pathological response to trastuzumab-paclitaxel neoadjuvant therapy in HER-2 positive breast cancer. Oncotarget. 2016.
    • (2016) Oncotarget
    • Miolo, G.1    Muraro, E.2    Caruso, D.3    Crivellari, D.4    Ash, A.5    Scalone, S.6
  • 69
    • 84992225600 scopus 로고    scopus 로고
    • National Cancer Institute Clinical Proteomic Tumor Analysis Consortium Accessed 29 July 2016
    • National Cancer Institute Clinical Proteomic Tumor Analysis Consortium. http://proteomics.cancer.gov/programs/cptacnetwork. Accessed 29 July 2016.
  • 70
    • 84973617999 scopus 로고    scopus 로고
    • Proteogenomics connects somatic mutations to signalling in breast cancer
    • 1:CAS:528:DC%2BC28XosFWht7Y%3D 27251275
    • Mertins P, Mani DR, Ruggles KV, Gillette MA, Clauser KR, Wang P, et al. Proteogenomics connects somatic mutations to signalling in breast cancer. Nature. 2016;534:55-62.
    • (2016) Nature , vol.534 , pp. 55-62
    • Mertins, P.1    Mani, D.R.2    Ruggles, K.V.3    Gillette, M.A.4    Clauser, K.R.5    Wang, P.6
  • 71
    • 84977611330 scopus 로고    scopus 로고
    • Integrated proteogenomic characterization of human high-grade serous ovarian cancer
    • 1:CAS:528:DC%2BC28XhtVymsrrE 27372738
    • Zhang H, Liu T, Zhang Z, Payne SH, Zhang B, McDermott JE, et al. Integrated proteogenomic characterization of human high-grade serous ovarian cancer. Cell. 2016;166:755-65.
    • (2016) Cell , vol.166 , pp. 755-765
    • Zhang, H.1    Liu, T.2    Zhang, Z.3    Payne, S.H.4    Zhang, B.5    McDermott, J.E.6
  • 75
    • 84940545374 scopus 로고    scopus 로고
    • Metabolomic signatures for drug response phenotypes: Pharmacometabolomics enables precision medicine
    • Pharmacometabolomics Research Network 1:CAS:528:DC%2BC2MXhtVOms7bE 25871646 4938244
    • Kaddurah-Daouk R, Weinshilboum R, Pharmacometabolomics Research Network. Metabolomic signatures for drug response phenotypes: pharmacometabolomics enables precision medicine. Clin Pharmacol Ther. 2015;98:71-5.
    • (2015) Clin Pharmacol Ther , vol.98 , pp. 71-75
    • Kaddurah-Daouk, R.1    Weinshilboum, R.2
  • 76
    • 84989811562 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration Accessed 29 July 2016
    • U.S. Food and Drug Administration. Table of pharmacogenomic biomarkers in drug labeling. http://www.fda.gov/Drugs/ScienceResearch/ResearchAreas/Pharmacogenetics/ucm083378.htm (2016). Accessed 29 July 2016.
    • (2016) Table of Pharmacogenomic Biomarkers in Drug Labeling
  • 77
    • 84894468169 scopus 로고    scopus 로고
    • Pharmacogenomic biomarkers in drug labels: What do they tell us?
    • 1:CAS:528:DC%2BC2cXisF2nt74%3D 24533709
    • Tutton R. Pharmacogenomic biomarkers in drug labels: what do they tell us? Pharmacogenomics. 2014;15:297-304.
    • (2014) Pharmacogenomics , vol.15 , pp. 297-304
    • Tutton, R.1
  • 78
    • 84904855033 scopus 로고    scopus 로고
    • U.S. Food and Drug Administration Accessed 29 July 2016
    • U.S. Food and Drug Administration. Nucleic acid based tests. http://www.fda.gov/MedicalDevices/ProductsandMedicalProcedures/InVitroDiagnostics/ucm330711.htm. Accessed 29 July 2016.
    • Nucleic Acid Based Tests
  • 80
    • 84930642392 scopus 로고    scopus 로고
    • FDA's draft guidance on laboratory-developed tests increases clinical and economic risk to adoption of pharmacogenetic testing
    • 26053647 4719776
    • Levy KD, Pratt VM, Skaar TC, Vance GH, Flockhart DA. FDA's draft guidance on laboratory-developed tests increases clinical and economic risk to adoption of pharmacogenetic testing. J Clin Pharmacol. 2015;55:725-7.
    • (2015) J Clin Pharmacol , vol.55 , pp. 725-727
    • Levy, K.D.1    Pratt, V.M.2    Skaar, T.C.3    Vance, G.H.4    Flockhart, D.A.5
  • 81
    • 84891774053 scopus 로고    scopus 로고
    • Translation of proteomic biomarkers into FDA approved cancer diagnostics: Issues and challenges
    • Fuzery AK, Levin J, Chan MM, Chan DW. Translation of proteomic biomarkers into FDA approved cancer diagnostics: issues and challenges. Clin Proteom. 2013;10:13.
    • (2013) Clin Proteom , vol.10 , pp. 13
    • Fuzery, A.K.1    Levin, J.2    Chan, M.M.3    Chan, D.W.4
  • 82
    • 76149142168 scopus 로고    scopus 로고
    • Repeatability and reproducibility in proteomic identifications by liquid chromatography - Tandem mass spectrometry
    • 1:CAS:528:DC%2BD1MXhsFGnt7bP 19921851 2818771
    • Tabb DL, Vega-Montoto L, Rudnick PA, Variyath AM, Ham AL, Bunk DM, et al. Repeatability and reproducibility in proteomic identifications by liquid chromatography - tandem mass spectrometry. J Proteome Res. 2010;9(2):761.
    • (2010) J Proteome Res , vol.9 , Issue.2 , pp. 761
    • Tabb, D.L.1    Vega-Montoto, L.2    Rudnick, P.A.3    Variyath, A.M.4    Ham, A.L.5    Bunk, D.M.6
  • 83
    • 67650564834 scopus 로고    scopus 로고
    • Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma
    • 1:CAS:528:DC%2BD1MXnslKqurY%3D 19561596 2855883
    • Addona TA, Abbatiello SE, Schilling B, Skates SJ, Mani DR, Bunk DM, et al. Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma. Nat Biotechnol. 2009;27:633-41.
    • (2009) Nat Biotechnol , vol.27 , pp. 633-641
    • Addona, T.A.1    Abbatiello, S.E.2    Schilling, B.3    Skates, S.J.4    Mani, D.R.5    Bunk, D.M.6
  • 84
    • 50649089207 scopus 로고    scopus 로고
    • RNA-seq: An assessment of technical reproducibility and comparison with gene expression arrays
    • 1:CAS:528:DC%2BD1cXhtV2qsr3E 18550803 2527709
    • Marioni JC, Mason CE, Mane SM, Stephens M, Gilad Y. RNA-seq: an assessment of technical reproducibility and comparison with gene expression arrays. Genome Res. 2008;18:1509-17.
    • (2008) Genome Res , vol.18 , pp. 1509-1517
    • Marioni, J.C.1    Mason, C.E.2    Mane, S.M.3    Stephens, M.4    Gilad, Y.5
  • 85
    • 84992200111 scopus 로고    scopus 로고
    • NIH Cancer Genome Atlas Accessed 8 Sept 2016
    • NIH Cancer Genome Atlas. http://cancergenome.nih.gov. Accessed 8 Sept 2016.
  • 87
    • 84954558940 scopus 로고    scopus 로고
    • Ambient ionization mass spectrometry for point-of-care diagnostics and other clinical measurements
    • 1:CAS:528:DC%2BC28Xos1aqsbc%3D 26467505
    • Ferreira CR, Yannell KE, Jarmusch AK, Pirro V, Ouyang Z, Cooks RG. Ambient ionization mass spectrometry for point-of-care diagnostics and other clinical measurements. Clin Chem. 2016;62:99-110.
    • (2016) Clin Chem , vol.62 , pp. 99-110
    • Ferreira, C.R.1    Yannell, K.E.2    Jarmusch, A.K.3    Pirro, V.4    Ouyang, Z.5    Cooks, R.G.6


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