-
1
-
-
0016979035
-
Population studies and the old order Amish
-
COI: 1:STN:280:DyaE283itVCkug%3D%3D, PID: 934323
-
Cross, H. E. (1976). Population studies and the old order Amish. Nature, 262(5563), 17–20.
-
(1976)
Nature
, vol.262
, Issue.5563
, pp. 17-20
-
-
Cross, H.E.1
-
2
-
-
84905390793
-
Pharmacometabolomics reveals that serotonin is implicated in aspirin response variability
-
COI: 1:CAS:528:DC%2BC2cXhsFagtbjP, PID: 25029353
-
Ellero-Simatos, S., Lewis, J. P., Georgiades, A., Yerges-Armstrong, L. M., Beitelshees, A. L., Horenstein, R. B., et al. (2014). Pharmacometabolomics reveals that serotonin is implicated in aspirin response variability. CPT: Pharmacometrics and Systems Pharmacology, 3, e125. doi:10.1038/psp.2014.22.
-
(2014)
CPT: Pharmacometrics and Systems Pharmacology
, vol.3
, pp. 125
-
-
Ellero-Simatos, S.1
Lewis, J.P.2
Georgiades, A.3
Yerges-Armstrong, L.M.4
Beitelshees, A.L.5
Horenstein, R.B.6
-
3
-
-
32344438563
-
Metabolic phenotyping of nude and normal (Alpk:ApfCD, C57BL10 J) mice
-
COI: 1:CAS:528:DC%2BD28XkvFKmuw%3D%3D, PID: 16457604
-
Gavaghan McKee, C. L., Wilson, I. D., & Nicholson, J. K. (2006). Metabolic phenotyping of nude and normal (Alpk:ApfCD, C57BL10 J) mice. Journal of Proteome Research, 5(2), 378–384. doi:10.1021/pr050255h.
-
(2006)
Journal of Proteome Research
, vol.5
, Issue.2
, pp. 378-384
-
-
Gavaghan McKee, C.L.1
Wilson, I.D.2
Nicholson, J.K.3
-
4
-
-
57149114936
-
Genetics meets metabolomics: A genome-wide association study of metabolite profiles in human serum
-
PID: 19043545
-
Gieger, C., Geistlinger, L., Altmaier, E., Hrabe de Angelis, M., Kronenberg, F., Meitinger, T., et al. (2008). Genetics meets metabolomics: A genome-wide association study of metabolite profiles in human serum. PLoS Genetics, 4(11), e1000282. doi:10.1371/journal.pgen.1000282.
-
(2008)
PLoS Genetics
, vol.4
, Issue.11
-
-
Gieger, C.1
Geistlinger, L.2
Altmaier, E.3
Hrabe de Angelis, M.4
Kronenberg, F.5
Meitinger, T.6
-
5
-
-
84959121708
-
TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: Pharmacometabolomics-informed pharmacogenomics
-
Gupta, M., Neavin, D., Liu, D., Biernacka, J., Hall-Flavin, D., Bobo, W. V., et al. (2016). TSPAN5, ERICH3 and selective serotonin reuptake inhibitors in major depressive disorder: Pharmacometabolomics-informed pharmacogenomics. Molecular Psychiatry. doi:10.1038/mp.2016.6.
-
(2016)
Molecular Psychiatry
-
-
Gupta, M.1
Neavin, D.2
Liu, D.3
Biernacka, J.4
Hall-Flavin, D.5
Bobo, W.V.6
-
6
-
-
75749134031
-
A genome-wide perspective of genetic variation in human metabolism
-
COI: 1:CAS:528:DC%2BD1MXhs1Skur7M, PID: 20037589
-
Illig, T., Gieger, C., Zhai, G., Romisch-Margl, W., Wang-Sattler, R., Prehn, C., et al. (2010). A genome-wide perspective of genetic variation in human metabolism. Nature Genetics, 42(2), 137–141. doi:10.1038/ng.507.
-
(2010)
Nature Genetics
, vol.42
, Issue.2
, pp. 137-141
-
-
Illig, T.1
Gieger, C.2
Zhai, G.3
Romisch-Margl, W.4
Wang-Sattler, R.5
Prehn, C.6
-
7
-
-
84880265900
-
Selective estrogen receptor modulators and pharmacogenomic variation in ZNF423 regulation of BRCA1 expression: Individualized breast cancer prevention
-
COI: 1:CAS:528:DC%2BC3sXhtFSrtLbJ, PID: 23764426
-
Ingle, J. N., Liu, M., Wickerham, D. L., Schaid, D. J., Wang, L., Mushiroda, T., et al. (2013). Selective estrogen receptor modulators and pharmacogenomic variation in ZNF423 regulation of BRCA1 expression: Individualized breast cancer prevention. Cancer Discovery, 3(7), 812–825. doi:10.1158/2159-8290.cd-13-0038.
-
(2013)
Cancer Discovery
, vol.3
, Issue.7
, pp. 812-825
-
-
Ingle, J.N.1
Liu, M.2
Wickerham, D.L.3
Schaid, D.J.4
Wang, L.5
Mushiroda, T.6
-
8
-
-
78149250018
-
Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors
-
COI: 1:CAS:528:DC%2BC3cXhsF2rtLzO, PID: 20876420
-
Ingle, J. N., Schaid, D. J., Goss, P. E., Liu, M., Mushiroda, T., Chapman, J. A., et al. (2010). Genome-wide associations and functional genomic studies of musculoskeletal adverse events in women receiving aromatase inhibitors. Journal of Clinical Oncology, 28(31), 4674–4682. doi:10.1200/jco.2010.28.5064.
-
(2010)
Journal of Clinical Oncology
, vol.28
, Issue.31
, pp. 4674-4682
-
-
Ingle, J.N.1
Schaid, D.J.2
Goss, P.E.3
Liu, M.4
Mushiroda, T.5
Chapman, J.A.6
-
9
-
-
84939883816
-
The interaction of escitalopram and R-citalopram at the human serotonin transporter investigated in the mouse
-
COI: 1:CAS:528:DC%2BC2cXns1Gks7Y%3D
-
Jacobsen, J. P., Plenge, P., Sachs, B. D., Pehrson, A. L., Cajina, M., Du, Y., et al. (2014). The interaction of escitalopram and R-citalopram at the human serotonin transporter investigated in the mouse. Psychopharmacology (Berl), 231(23), 4527–4540. doi:10.1007/s00213-014-3595-1.
-
(2014)
Psychopharmacology (Berl)
, vol.231
, Issue.23
, pp. 4527-4540
-
-
Jacobsen, J.P.1
Plenge, P.2
Sachs, B.D.3
Pehrson, A.L.4
Cajina, M.5
Du, Y.6
-
10
-
-
84884592615
-
Pharmacogenomics of selective serotonin reuptake inhibitor treatment for major depressive disorder: Genome-wide associations and functional genomics
-
COI: 1:CAS:528:DC%2BC38Xht1akt7%2FK, PID: 22907730
-
Ji, Y., Biernacka, J. M., Hebbring, S., Chai, Y., Jenkins, G. D., Batzler, A., et al. (2013). Pharmacogenomics of selective serotonin reuptake inhibitor treatment for major depressive disorder: Genome-wide associations and functional genomics. The pharmacogenomics Journal, 13(5), 456–463. doi:10.1038/tpj.2012.32.
-
(2013)
The pharmacogenomics Journal
, vol.13
, Issue.5
, pp. 456-463
-
-
Ji, Y.1
Biernacka, J.M.2
Hebbring, S.3
Chai, Y.4
Jenkins, G.D.5
Batzler, A.6
-
11
-
-
78650513748
-
Glycine and a glycine dehydrogenase (GLDC) SNP as citalopram/escitalopram response biomarkers in depression: Pharmacometabolomics-informed pharmacogenomics
-
COI: 1:CAS:528:DC%2BC3cXhsFylt7%2FF, PID: 21107318
-
Ji, Y., Hebbring, S., Zhu, H., Jenkins, G. D., Biernacka, J., Snyder, K., et al. (2011). Glycine and a glycine dehydrogenase (GLDC) SNP as citalopram/escitalopram response biomarkers in depression: Pharmacometabolomics-informed pharmacogenomics. Clinical Pharmacology and Therapeutics, 89(1), 97–104. doi:10.1038/clpt.2010.250.
-
(2011)
Clinical Pharmacology and Therapeutics
, vol.89
, Issue.1
, pp. 97-104
-
-
Ji, Y.1
Hebbring, S.2
Zhu, H.3
Jenkins, G.D.4
Biernacka, J.5
Snyder, K.6
-
12
-
-
84904907494
-
Citalopram and escitalopram plasma drug and metabolite concentrations: Genome-wide associations
-
COI: 1:CAS:528:DC%2BC2cXht1SmtL%2FJ, PID: 24528284
-
Ji, Y., Schaid, D. J., Desta, Z., Kubo, M., Batzler, A. J., Snyder, K., et al. (2014). Citalopram and escitalopram plasma drug and metabolite concentrations: Genome-wide associations. British Journal of Clinical Pharmacology, 78(2), 373–383. doi:10.1111/bcp.12348.
-
(2014)
British Journal of Clinical Pharmacology
, vol.78
, Issue.2
, pp. 373-383
-
-
Ji, Y.1
Schaid, D.J.2
Desta, Z.3
Kubo, M.4
Batzler, A.J.5
Snyder, K.6
-
13
-
-
41149162296
-
Metabolomics: A global biochemical approach to drug response and disease
-
COI: 1:CAS:528:DC%2BD1cXisFymsrk%3D, PID: 18184107
-
Kaddurah-Daouk, R., Kristal, B. S., & Weinshilboum, R. M. (2008). Metabolomics: A global biochemical approach to drug response and disease. Annual Review of Pharmacology and Toxicology, 48, 653–683. doi:10.1146/annurev.pharmtox.48.113006.094715.
-
(2008)
Annual Review of Pharmacology and Toxicology
, vol.48
, pp. 653-683
-
-
Kaddurah-Daouk, R.1
Kristal, B.S.2
Weinshilboum, R.M.3
-
14
-
-
84893763297
-
Pharmacometabolomics: Implications for clinical pharmacology and systems pharmacology
-
COI: 1:CAS:528:DC%2BC2cXmtlSnug%3D%3D, PID: 24193171
-
Kaddurah-Daouk, R., & Weinshilboum, R. M. (2014). Pharmacometabolomics: Implications for clinical pharmacology and systems pharmacology. Clinical Pharmacology and Therapeutics, 95(2), 154–167. doi:10.1038/clpt.2013.217.
-
(2014)
Clinical Pharmacology and Therapeutics
, vol.95
, Issue.2
, pp. 154-167
-
-
Kaddurah-Daouk, R.1
Weinshilboum, R.M.2
-
15
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
COI: 1:CAS:528:DC%2BD3MXhsFCjtLc%3D, PID: 11237011
-
Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C., Zody, M. C., Baldwin, J., et al. (2001). Initial sequencing and analysis of the human genome. Nature, 409(6822), 860–921. doi:10.1038/35057062.
-
(2001)
Nature
, vol.409
, Issue.6822
, pp. 860-921
-
-
Lander, E.S.1
Linton, L.M.2
Birren, B.3
Nusbaum, C.4
Zody, M.C.5
Baldwin, J.6
-
16
-
-
84886727080
-
Integration of pharmacometabolomic and pharmacogenomic approaches reveals novel insights into antiplatelet therapy
-
COI: 1:CAS:528:DC%2BC3sXhsFymsrjO, PID: 23892404
-
Lewis, J. P., Yerges-Armstrong, L. M., Ellero-Simatos, S., Georgiades, A., Kaddurah-Daouk, R., & Hankemeier, T. (2013). Integration of pharmacometabolomic and pharmacogenomic approaches reveals novel insights into antiplatelet therapy. Clinical Pharmacology and Therapeutics, 94(5), 570–573. doi:10.1038/clpt.2013.153.
-
(2013)
Clinical Pharmacology and Therapeutics
, vol.94
, Issue.5
, pp. 570-573
-
-
Lewis, J.P.1
Yerges-Armstrong, L.M.2
Ellero-Simatos, S.3
Georgiades, A.4
Kaddurah-Daouk, R.5
Hankemeier, T.6
-
17
-
-
42649109683
-
The genetic response to short-term interventions affecting cardiovascular function: Rationale and design of the Heredity and Phenotype Intervention (HAPI) Heart Study
-
PID: 18440328
-
Mitchell, B. D., McArdle, P. F., Shen, H., Rampersaud, E., Pollin, T. I., Bielak, L. F., et al. (2008). The genetic response to short-term interventions affecting cardiovascular function: Rationale and design of the Heredity and Phenotype Intervention (HAPI) Heart Study. American Heart Journal, 155(5), 823–828. doi:10.1016/j.ahj.2008.01.019.
-
(2008)
American Heart Journal
, vol.155
, Issue.5
, pp. 823-828
-
-
Mitchell, B.D.1
McArdle, P.F.2
Shen, H.3
Rampersaud, E.4
Pollin, T.I.5
Bielak, L.F.6
-
18
-
-
80052398214
-
Human metabolic individuality in biomedical and pharmaceutical research
-
COI: 1:CAS:528:DC%2BC3MXhtFWku7nN, PID: 21886157
-
Suhre, K., Shin, S. Y., Petersen, A. K., Mohney, R. P., Meredith, D., Wagele, B., et al. (2011). Human metabolic individuality in biomedical and pharmaceutical research. Nature, 477(7362), 54–60. doi:10.1038/nature10354.
-
(2011)
Nature
, vol.477
, Issue.7362
, pp. 54-60
-
-
Suhre, K.1
Shin, S.Y.2
Petersen, A.K.3
Mohney, R.P.4
Meredith, D.5
Wagele, B.6
-
19
-
-
79953174333
-
Genomics and drug response
-
COI: 1:CAS:528:DC%2BC3MXktVygsrk%3D, PID: 21428770
-
Wang, L., McLeod, H. L., & Weinshilboum, R. M. (2011). Genomics and drug response. New England Journal of Medicine, 364(12), 1144–1153. doi:10.1056/NEJMra1010600.
-
(2011)
New England Journal of Medicine
, vol.364
, Issue.12
, pp. 1144-1153
-
-
Wang, L.1
McLeod, H.L.2
Weinshilboum, R.M.3
-
20
-
-
84960387071
-
Emerging applications of metabolomics in drug discovery and precision medicine
-
PID: 26965202
-
Wishart, D. S. (2016). Emerging applications of metabolomics in drug discovery and precision medicine. Nature Reviews Drug Discovery. doi:10.1038/nrd.2016.32.
-
(2016)
Nature Reviews Drug Discovery
-
-
Wishart, D.S.1
-
21
-
-
33750111733
-
An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate
-
COI: 1:CAS:528:DC%2BD28XpsVyku7Y%3D, PID: 17022638
-
Yap, I. K., Clayton, T. A., Tang, H., Everett, J. R., Hanton, G., Provost, J. P., et al. (2006). An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5(10), 2675–2684. doi:10.1021/pr0601584.
-
(2006)
Journal of Proteome Research
, vol.5
, Issue.10
, pp. 2675-2684
-
-
Yap, I.K.1
Clayton, T.A.2
Tang, H.3
Everett, J.R.4
Hanton, G.5
Provost, J.P.6
-
22
-
-
84884502711
-
Purine pathway implicated in mechanism of resistance to aspirin therapy: Pharmacometabolomics-informed pharmacogenomics
-
COI: 1:CAS:528:DC%2BC3sXhsVyqtrbJ, PID: 23839601
-
Yerges-Armstrong, L. M., Ellero-Simatos, S., Georgiades, A., Zhu, H., Lewis, J. P., Horenstein, R. B., et al. (2013). Purine pathway implicated in mechanism of resistance to aspirin therapy: Pharmacometabolomics-informed pharmacogenomics. Clinical Pharmacology and Therapeutics, 94(4), 525–532. doi:10.1038/clpt.2013.119.
-
(2013)
Clinical Pharmacology and Therapeutics
, vol.94
, Issue.4
, pp. 525-532
-
-
Yerges-Armstrong, L.M.1
Ellero-Simatos, S.2
Georgiades, A.3
Zhu, H.4
Lewis, J.P.5
Horenstein, R.B.6
-
23
-
-
67849119253
-
An allosteric binding site at the human serotonin transporter mediates the inhibition of escitalopram by R-citalopram: Kinetic binding studies with the ALI/VFL-SI/TT mutant
-
COI: 1:CAS:528:DC%2BD1MXptlSktb0%3D, PID: 19616061
-
Zhong, H., Hansen, K. B., Boyle, N. J., Han, K., Muske, G., Huang, X., et al. (2009). An allosteric binding site at the human serotonin transporter mediates the inhibition of escitalopram by R-citalopram: Kinetic binding studies with the ALI/VFL-SI/TT mutant. Neuroscience Letters, 462(3), 207–212. doi:10.1016/j.neulet.2009.07.030.
-
(2009)
Neuroscience Letters
, vol.462
, Issue.3
, pp. 207-212
-
-
Zhong, H.1
Hansen, K.B.2
Boyle, N.J.3
Han, K.4
Muske, G.5
Huang, X.6
|