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Volumn 18, Issue 4, 2004, Pages 413-422

Pharmacoproteomic approach to the study of drug mode of action, toxicity, and resistance: Applications in diabetes and cancer

Author keywords

Bioinformatics; Cancer; Diabetes; Mass spectrometry; Pharmacoproteomics; Proteomics; Two dimensional gel electrophoresis

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; A 204197; ANTIDIABETIC AGENT; ANTIMITOTIC AGENT; CISPLATIN; CLOFIBRIC ACID; DAUNORUBICIN; DOXORUBICIN; ETOMOXIR; ETOPOSIDE; MITOXANTRONE; NAFENOPIN; ORAL ANTIDIABETIC AGENT; PACLITAXEL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; PIRINIXIC ACID; PROTEIN KINASE C; ROSIGLITAZONE; SDZ PUG 693; THIOREDOXIN; TOMELUKAST; TUMOR MARKER; UNCLASSIFIED DRUG; VINCRISTINE;

EID: 4544306096     PISSN: 07673981     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1472-8206.2004.00258.x     Document Type: Review
Times cited : (23)

References (59)
  • 1
    • 0029033175 scopus 로고
    • Progress with gene-product mapping of the Mollicutes: Mycoplasma genitalium
    • Wasinger V.C., Cordwell S.J., Cerpa-Poljak A. et al. Progress with gene-product mapping of the Mollicutes: Mycoplasma genitalium. Electrophoresis (1995) 16 1090-1094.
    • (1995) Electrophoresis , vol.16 , pp. 1090-1094
    • Wasinger, V.C.1    Cordwell, S.J.2    Cerpa-Poljak, A.3
  • 2
    • 0034659815 scopus 로고    scopus 로고
    • Proteomics to study genes and genomes
    • Pandey A., Mann M. Proteomics to study genes and genomes. Nature (2000) 405 837-846.
    • (2000) Nature , vol.405 , pp. 837-846
    • Pandey, A.1    Mann, M.2
  • 3
    • 0035397916 scopus 로고    scopus 로고
    • Proteomics - Post-genomic cartography to understand gene function
    • Naaby-Hansen S., Waterfield M.D., Cramer R. Proteomics - post-genomic cartography to understand gene function. Trends Pharmacol. Sci. (2001) 22 376-384.
    • (2001) Trends Pharmacol. Sci. , vol.22 , pp. 376-384
    • Naaby-Hansen, S.1    Waterfield, M.D.2    Cramer, R.3
  • 4
    • 0035225642 scopus 로고    scopus 로고
    • The mouse SWISS-20 PAGE database: A tool for proteomics study of diabetes and obesity
    • Sanchez J.C., Chiappe D., Converset V. et al. The mouse SWISS-20 PAGE database: a tool for proteomics study of diabetes and obesity. Proteomics (2001) 1 136-163.
    • (2001) Proteomics , vol.1 , pp. 136-163
    • Sanchez, J.C.1    Chiappe, D.2    Converset, V.3
  • 5
    • 0036629907 scopus 로고    scopus 로고
    • Human proteomic databases: A powerful resource for functional genomics in health and disease
    • Gromov P.S., Ostergaard M., Gromova I., Celis J.E. Human proteomic databases: a powerful resource for functional genomics in health and disease. Prog. Biophys. Mol. Biol. (2002) 80 3-22.
    • (2002) Prog. Biophys. Mol. Biol. , vol.80 , pp. 3-22
    • Gromov, P.S.1    Ostergaard, M.2    Gromova, I.3    Celis, J.E.4
  • 6
    • 0035856920 scopus 로고    scopus 로고
    • Global and societal implications of the diabetes epidemic
    • Zimmet P., Alberti K.G., Shaw J. Global and societal implications of the diabetes epidemic. Nature (2001) 414 782-787.
    • (2001) Nature , vol.414 , pp. 782-787
    • Zimmet, P.1    Alberti, K.G.2    Shaw, J.3
  • 7
    • 0028954346 scopus 로고
    • Two-dimensional gel electrophoresis of rat islet proteins. Interleukin 1 beta-induced changes in protein expression are reduced by L-arginine depletion and nicotinamide
    • Andersen H.U., Larsen P.M., Fey S.J., Karlsen A.E., Mandrup-Poulsen T., Nerup J. Two-dimensional gel electrophoresis of rat islet proteins. Interleukin 1 beta-induced changes in protein expression are reduced by L-arginine depletion and nicotinamide. Diabetes (1995) 44 400-407.
    • (1995) Diabetes , vol.44 , pp. 400-407
    • Andersen, H.U.1    Larsen, P.M.2    Fey, S.J.3    Karlsen, A.E.4    Mandrup-Poulsen, T.5    Nerup, J.6
  • 8
    • 0030608664 scopus 로고    scopus 로고
    • Interleukin-1beta induced changes in the protein expression of rat islets: A computerized database
    • Andersen H.U., Fey S.J., Larsen P.M. et al. Interleukin-1beta induced changes in the protein expression of rat islets: a computerized database. Electrophoresis (1997) 18 2091-2103.
    • (1997) Electrophoresis , vol.18 , pp. 2091-2103
    • Andersen, H.U.1    Fey, S.J.2    Larsen, P.M.3
  • 9
    • 0033755391 scopus 로고    scopus 로고
    • Cytokine- or chemically derived nitric oxide alters the expression of proteins detected by two-dimensional gel electrophoresis in neonatal rat islets of Langerhans
    • John N.E., Andersen H.U., Fey S.J. et al. Cytokine- or chemically derived nitric oxide alters the expression of proteins detected by two-dimensional gel electrophoresis in neonatal rat islets of Langerhans. Diabetes (2000) 49 1819-1829.
    • (2000) Diabetes , vol.49 , pp. 1819-1829
    • John, N.E.1    Andersen, H.U.2    Fey, S.J.3
  • 10
    • 0035033679 scopus 로고    scopus 로고
    • Proteome analysis of interleukin-1beta-induced changes in protein expression in rat islets of Langerhans
    • Larsen P.M., Fey S.J., Larsen M.R. et al. Proteome analysis of interleukin-1beta-induced changes in protein expression in rat islets of Langerhans. Diabetes (2001) 50 1056-1063.
    • (2001) Diabetes , vol.50 , pp. 1056-1063
    • Larsen, P.M.1    Fey, S.J.2    Larsen, M.R.3
  • 11
    • 0035857020 scopus 로고    scopus 로고
    • New drug targets for type 2 diabetes and the metabolic syndrome
    • Moller D.E. New drug targets for type 2 diabetes and the metabolic syndrome. Nature (2001) 414 821-827.
    • (2001) Nature , vol.414 , pp. 821-827
    • Moller, D.E.1
  • 12
    • 0035403552 scopus 로고    scopus 로고
    • Thiourea enhances mapping of the proteome from murine white adipose tissue
    • Lanne B., Potthast F., Hoglund A. et al. Thiourea enhances mapping of the proteome from murine white adipose tissue. Proteomics (2001) 1 819-828.
    • (2001) Proteomics , vol.1 , pp. 819-828
    • Lanne, B.1    Potthast, F.2    Hoglund, A.3
  • 13
    • 0035294573 scopus 로고    scopus 로고
    • Separation and identification of rat skeletal muscle proteins using two-dimensional gel electrophoresis and mass spectrometry
    • Yan J.X., Harry R.A., Wait R. et al. Separation and identification of rat skeletal muscle proteins using two-dimensional gel electrophoresis and mass spectrometry. Proteomics (2001) 1 424-434.
    • (2001) Proteomics , vol.1 , pp. 424-434
    • Yan, J.X.1    Harry, R.A.2    Wait, R.3
  • 14
    • 0033920278 scopus 로고    scopus 로고
    • Two-dimensional database of mouse liver proteins: Changes in hepatic protein levels following treatment with acetaminophen or its nontoxic regioisomer 3-acetamidophenol
    • Fountoulakis M., Berndt P., Boelsterli U.A. et al. Two-dimensional database of mouse liver proteins: changes in hepatic protein levels following treatment with acetaminophen or its nontoxic regioisomer 3-acetamidophenol. Electrophoresis (2000) 21 2148-2161.
    • (2000) Electrophoresis , vol.21 , pp. 2148-2161
    • Fountoulakis, M.1    Berndt, P.2    Boelsterli, U.A.3
  • 17
    • 0033769442 scopus 로고    scopus 로고
    • High-throughput profiling of the mitochondrial proteome using affinity fractionation and automation
    • Lopez M.F., Kristal B.S., Chernokalskaya E. et al. High-throughput profiling of the mitochondrial proteome using affinity fractionation and automation. Electrophoresis (2000) 21 3427-3440.
    • (2000) Electrophoresis , vol.21 , pp. 3427-3440
    • Lopez, M.F.1    Kristal, B.S.2    Chernokalskaya, E.3
  • 18
    • 0033769457 scopus 로고    scopus 로고
    • Proteomics of rat liver Golgi complex: Minor proteins are identified through sequential fractionation
    • Taylor R.S., Wu C.C., Hays L.G., Eng J.K., Yates J.R. III, Howell K.E. Proteomics of rat liver Golgi complex: minor proteins are identified through sequential fractionation. Electrophoresis (2000) 21 3441-3459.
    • (2000) Electrophoresis , vol.21 , pp. 3441-3459
    • Taylor, R.S.1    Wu, C.C.2    Hays, L.G.3    Eng, J.K.4    Yates III, J.R.5    Howell, K.E.6
  • 19
    • 0027050391 scopus 로고
    • Human liver protein map: A reference database established by microsequencing and gel comparison
    • Hochstrasser D.F., Frutiger S., Paquet N. et al. Human liver protein map: a reference database established by microsequencing and gel comparison. Electrophoresis (1992) 13 992-1001.
    • (1992) Electrophoresis , vol.13 , pp. 992-1001
    • Hochstrasser, D.F.1    Frutiger, S.2    Paquet, N.3
  • 20
    • 0027433601 scopus 로고
    • Human liver protein map: Update 1993
    • Hughes G.J., Frutiger S., Paquet N. et al. Human liver protein map: update 1993. Electrophoresis (1993) 14 1216-1222.
    • (1993) Electrophoresis , vol.14 , pp. 1216-1222
    • Hughes, G.J.1    Frutiger, S.2    Paquet, N.3
  • 21
    • 0036255529 scopus 로고    scopus 로고
    • The mode of action of thiazolidinediones
    • Hauner H. The mode of action of thiazolidinediones. Diabetes Metab. Res. Rev. (2002) 18 S10-S15.
    • (2002) Diabetes Metab. Res. Rev. , vol.18
    • Hauner, H.1
  • 23
    • 0032951971 scopus 로고    scopus 로고
    • A proteome analysis of livers from obese (ob/ob) mice treated with the peroxisome proliferator WY14,643
    • Edvardsson U., Alexandersson M., Brockenhuus von Lowenhielm H. et al. A proteome analysis of livers from obese (ob/ob) mice treated with the peroxisome proliferator WY14,643. Electrophoresis (1999) 20 935-942.
    • (1999) Electrophoresis , vol.20 , pp. 935-942
    • Edvardsson, U.1    Alexandersson, M.2    Brockenhuus Von Lowenhielm, H.3
  • 24
    • 0037388895 scopus 로고    scopus 로고
    • Hepatic protein expression of lean mice and obese diabetic mice treated with peroxisome proliferator-activated receptor activators
    • Edvardsson U., Brockenhuus Von Lowenhielm H., Panfilov O., Nystrom A.C., Nilsson F., Dahllof B. Hepatic protein expression of lean mice and obese diabetic mice treated with peroxisome proliferator-activated receptor activators. Proteomics (2003) 3 468-478.
    • (2003) Proteomics , vol.3 , pp. 468-478
    • Edvardsson, U.1    Brockenhuus Von Lowenhielm, H.2    Panfilov, O.3    Nystrom, A.C.4    Nilsson, F.5    Dahllof, B.6
  • 25
    • 0036652155 scopus 로고    scopus 로고
    • Effect of rosiglitazone on the differential expression of diabetes-associated proteins in pancreatic islets of C57B1/6 lep/lep mice
    • Sanchez J.C., Converset V., Nolan A. et al. Effect of rosiglitazone on the differential expression of diabetes-associated proteins in pancreatic islets of C57B1/6 lep/lep mice. Mol. Cell. Proteomics (2002) 1 509-516.
    • (2002) Mol. Cell. Proteomics , vol.1 , pp. 509-516
    • Sanchez, J.C.1    Converset, V.2    Nolan, A.3
  • 26
    • 0041358763 scopus 로고    scopus 로고
    • Effect of rosiglitazone on the differential expression of obesity and insulin resistance associated proteins in lep/lep mice
    • Sanchez J.C., Converset V., Nolan A. et al. Effect of rosiglitazone on the differential expression of obesity and insulin resistance associated proteins in lep/lep mice. Proteomics (2003) 3 1500-1520.
    • (2003) Proteomics , vol.3 , pp. 1500-1520
    • Sanchez, J.C.1    Converset, V.2    Nolan, A.3
  • 27
    • 0036525708 scopus 로고    scopus 로고
    • Toxicoproteomics: A new preclinical tool
    • Bandara L.R., Kennedy S. Toxicoproteomics: a new preclinical tool. Drug Discov. Today (2002) 7 411-418.
    • (2002) Drug Discov. Today , vol.7 , pp. 411-418
    • Bandara, L.R.1    Kennedy, S.2
  • 28
    • 0036649486 scopus 로고    scopus 로고
    • The role of proteomics in toxicology: Identification of biomarkers of toxicity by protein expression analysis
    • Kennedy S. The role of proteomics in toxicology: identification of biomarkers of toxicity by protein expression analysis. Biomarkers (2002) 7 269-290.
    • (2002) Biomarkers , vol.7 , pp. 269-290
    • Kennedy, S.1
  • 29
    • 0030031906 scopus 로고    scopus 로고
    • Induction of the adipose differentiation-related protein in liver of etomoxir-treated rats
    • Steiner S., Wahl D., Mangold B.L. et al. Induction of the adipose differentiation-related protein in liver of etomoxir-treated rats. Biochem. Biophys. Res. Commun. (1996) 218 777-782.
    • (1996) Biochem. Biophys. Res. Commun. , vol.218 , pp. 777-782
    • Steiner, S.1    Wahl, D.2    Mangold, B.L.3
  • 30
    • 0032514958 scopus 로고    scopus 로고
    • Changes in the liver protein pattern of female Wistar rats treated with the hypoglycemic agent SDZ PGU 693
    • Arce A., Aicher L., Wahl D. et al. Changes in the liver protein pattern of female Wistar rats treated with the hypoglycemic agent SDZ PGU 693. Life Sci. (1998) 63 2243-2250.
    • (1998) Life Sci. , vol.63 , pp. 2243-2250
    • Arce, A.1    Aicher, L.2    Wahl, D.3
  • 31
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of ATP-dependent transporters
    • Gottesman M.M., Fojo T., Bates S.E. Multidrug resistance in cancer: role of ATP-dependent transporters. Nat. Rev. Cancer (2002) 2 48-58.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 32
    • 0035489609 scopus 로고    scopus 로고
    • Proteomics for studying cancer cells and the development of chemoresistance
    • Hutter G., Sinha P. Proteomics for studying cancer cells and the development of chemoresistance. Proteomics (2001) 1 1233-1248.
    • (2001) Proteomics , vol.1 , pp. 1233-1248
    • Hutter, G.1    Sinha, P.2
  • 33
    • 0036176510 scopus 로고    scopus 로고
    • Mechanisms of cancer drug resistance
    • Gottesman M.M. Mechanisms of cancer drug resistance. Annu. Rev. Med. (2002) 53 615-627.
    • (2002) Annu. Rev. Med. , vol.53 , pp. 615-627
    • Gottesman, M.M.1
  • 34
    • 0029074342 scopus 로고
    • Associated expression of protein kinase C with resistance to doxorubicin in human lung cancer
    • Volm M., Pommerenke E.W. Associated expression of protein kinase C with resistance to doxorubicin in human lung cancer. Anticancer Res. (1995) 15 463-466.
    • (1995) Anticancer Res. , vol.15 , pp. 463-466
    • Volm, M.1    Pommerenke, E.W.2
  • 35
    • 0035422780 scopus 로고    scopus 로고
    • Multiple microtubule alterations are associated with Vinca alkaloid resistance in human leukemia cells
    • Kavallaris M., Tait A.S., Walsh B.J. et al. Multiple microtubule alterations are associated with Vinca alkaloid resistance in human leukemia cells. Cancer Res. (2001) 61 5803-5809.
    • (2001) Cancer Res. , vol.61 , pp. 5803-5809
    • Kavallaris, M.1    Tait, A.S.2    Walsh, B.J.3
  • 36
    • 0344131934 scopus 로고    scopus 로고
    • Increased expression of epidermal fatty acid binding protein, cofilin, and 14-3-3-sigma (stratifin) detected by two-dimensional gel electrophoresis, mass spectrometry and microsequencing of drug-resistant human adenocarcinoma of the pancreas
    • Sinha P., Hutter G., Kottgen E., Dietel M., Schadendorf D., Lage H. Increased expression of epidermal fatty acid binding protein, cofilin, and 14-3-3-sigma (stratifin) detected by two-dimensional gel electrophoresis, mass spectrometry and microsequencing of drug-resistant human adenocarcinoma of the pancreas. Electrophoresis (1999) 20 2952-2960.
    • (1999) Electrophoresis , vol.20 , pp. 2952-2960
    • Sinha, P.1    Hutter, G.2    Kottgen, E.3    Dietel, M.4    Schadendorf, D.5    Lage, H.6
  • 37
    • 0035987497 scopus 로고    scopus 로고
    • Monitoring daunorubicin-induced alterations in protein expression in pancreas carcinoma cells by two-dimensional gel electrophoresis
    • Moller A., Malerczyk C., Volker U., Stoppler H., Maser E. Monitoring daunorubicin-induced alterations in protein expression in pancreas carcinoma cells by two-dimensional gel electrophoresis. Proteomics (2002) 2 697-705.
    • (2002) Proteomics , vol.2 , pp. 697-705
    • Moller, A.1    Malerczyk, C.2    Volker, U.3    Stoppler, H.4    Maser, E.5
  • 38
    • 0033811376 scopus 로고    scopus 로고
    • Identification of novel proteins associated with the development of chemoresistance in malignant melanoma using two-dimensional electrophoresis
    • Sinha P., Kohl S., Fischer J. et al. Identification of novel proteins associated with the development of chemoresistance in malignant melanoma using two-dimensional electrophoresis. Electrophoresis (2000) 21 3048-3057.
    • (2000) Electrophoresis , vol.21 , pp. 3048-3057
    • Sinha, P.1    Kohl, S.2    Fischer, J.3
  • 39
    • 0345516042 scopus 로고    scopus 로고
    • Increased expression of annexin I and thioredoxin detected by two-dimensional gel electrophoresis of drug resistant human stomach cancer cells
    • Sinha P., Hutter G., Kottgen E., Dietel M., Schadendorf D., Lage H. Increased expression of annexin I and thioredoxin detected by two-dimensional gel electrophoresis of drug resistant human stomach cancer cells. J. Biochem. Biophys. Methods (1998) 37 105-116.
    • (1998) J. Biochem. Biophys. Methods , vol.37 , pp. 105-116
    • Sinha, P.1    Hutter, G.2    Kottgen, E.3    Dietel, M.4    Schadendorf, D.5    Lage, H.6
  • 40
    • 0026513632 scopus 로고
    • Elevated expression of annexin II (lipocortin II, p36) in a multidrug resistant small cell lung cancer cell line
    • Cole S.P., Pinkoski M.J., Bhardwaj G., Deeley R.G. Elevated expression of annexin II (lipocortin II, p36) in a multidrug resistant small cell lung cancer cell line. Br. J. Cancer (1992) 65 498-502.
    • (1992) Br. J. Cancer , vol.65 , pp. 498-502
    • Cole, S.P.1    Pinkoski, M.J.2    Bhardwaj, G.3    Deeley, R.G.4
  • 41
    • 0344721482 scopus 로고    scopus 로고
    • Search for novel proteins involved in the development of chemoresistance in colorectal cancer and fibrosarcoma cells in vitro using two-dimensional electrophoresis, mass spectrometry and microsequencing
    • Sinha P., Hutter G., Kottgen E., Dietel M., Schadendorf D., Lage H. Search for novel proteins involved in the development of chemoresistance in colorectal cancer and fibrosarcoma cells in vitro using two-dimensional electrophoresis, mass spectrometry and microsequencing. Electrophoresis (1999) 20 2961-2969.
    • (1999) Electrophoresis , vol.20 , pp. 2961-2969
    • Sinha, P.1    Hutter, G.2    Kottgen, E.3    Dietel, M.4    Schadendorf, D.5    Lage, H.6
  • 42
    • 0029051872 scopus 로고
    • Cellular levels of thioredoxin associated with drug sensitivity to cisplatin, mitomycin C, doxorubicin, and etoposide
    • Yokomizo A., Ono M., Nanri H. et al. Cellular levels of thioredoxin associated with drug sensitivity to cisplatin, mitomycin C, doxorubicin, and etoposide. Cancer Res. (1995) 55 4293-4296.
    • (1995) Cancer Res. , vol.55 , pp. 4293-4296
    • Yokomizo, A.1    Ono, M.2    Nanri, H.3
  • 43
    • 0030598936 scopus 로고    scopus 로고
    • Microtubule-dependent multilobular organization of the nucleus in sensitive and multidrug-resistant L0 leukemia cells
    • Huang J., Sweet P., Slater L.M., Sartorelli A.C., Leung M.F. Microtubule-dependent multilobular organization of the nucleus in sensitive and multidrug-resistant L0 leukemia cells. Cancer Lett. (1996) 106 29-41.
    • (1996) Cancer Lett. , vol.106 , pp. 29-41
    • Huang, J.1    Sweet, P.2    Slater, L.M.3    Sartorelli, A.C.4    Leung, M.F.5
  • 44
    • 0034078907 scopus 로고    scopus 로고
    • Modulation of paclitaxel resistance by annexin IV in human cancer cell lines
    • Han E.K., Tahir S.K., Cherian S.P., Collins N., Ng S.C. Modulation of paclitaxel resistance by annexin IV in human cancer cell lines. Br. J. Cancer (2000) 83 83-88.
    • (2000) Br. J. Cancer , vol.83 , pp. 83-88
    • Han, E.K.1    Tahir, S.K.2    Cherian, S.P.3    Collins, N.4    Ng, S.C.5
  • 45
    • 1842387251 scopus 로고
    • Phorbol esters induce multidrug resistance in human breast cancer cells
    • Fine R.L., Patel J., Chabner B.A. Phorbol esters induce multidrug resistance in human breast cancer cells. Proc. Natl. Acad. Sci. U. S. A. (1988) 85 582-586.
    • (1988) Proc. Natl. Acad. Sci. U. S. A. , vol.85 , pp. 582-586
    • Fine, R.L.1    Patel, J.2    Chabner, B.A.3
  • 46
    • 0029956761 scopus 로고    scopus 로고
    • Characterization of the protein kinase C signal transduction pathway in cisplatin-sensitive and -resistant human small cell lung carcinoma cells
    • Basu A., Weixel K., Saijo N. Characterization of the protein kinase C signal transduction pathway in cisplatin-sensitive and -resistant human small cell lung carcinoma cells. Cell Growth Differ. (1996) 7 1507-1512.
    • (1996) Cell Growth Differ. , vol.7 , pp. 1507-1512
    • Basu, A.1    Weixel, K.2    Saijo, N.3
  • 47
    • 0028840769 scopus 로고
    • Stratifin, a keratinocyte specific 14-3-3 protein, harbors a pleckstrin homology (PH) domain and enhances protein kinase C activity
    • Dellambra E., Patrone M., Sparatore B. et al. Stratifin, a keratinocyte specific 14-3-3 protein, harbors a pleckstrin homology (PH) domain and enhances protein kinase C activity. J. Cell Sci. (1995) 108 3569-3579.
    • (1995) J. Cell Sci. , vol.108 , pp. 3569-3579
    • Dellambra, E.1    Patrone, M.2    Sparatore, B.3
  • 48
    • 0027076352 scopus 로고
    • Inhibitory effect of mitoxantrone on activity of protein kinase C and growth of HL60 cells
    • Tokyo
    • Takeuchi N., Nakamura T., Takeuchi F., Hashimoto E., Yamamura H. Inhibitory effect of mitoxantrone on activity of protein kinase C and growth of HL60 cells. J. Biochem. (Tokyo) (1992) 112 762-767.
    • (1992) J. Biochem. , vol.112 , pp. 762-767
    • Takeuchi, N.1    Nakamura, T.2    Takeuchi, F.3    Hashimoto, E.4    Yamamura, H.5
  • 49
    • 0032254614 scopus 로고    scopus 로고
    • Dexamethasone-induced cytotoxic activity and drug resistance effects in androgen-independent prostate tumor PC-3 cells are mediated by lipocortin 1
    • Carollo M., Parente L., D'Alessandro N. Dexamethasone-induced cytotoxic activity and drug resistance effects in androgen-independent prostate tumor PC-3 cells are mediated by lipocortin 1. Oncol. Res. (1998) 10 245-254.
    • (1998) Oncol. Res. , vol.10 , pp. 245-254
    • Carollo, M.1    Parente, L.2    D'Alessandro, N.3
  • 50
    • 0034492231 scopus 로고    scopus 로고
    • Upregulation of lipocortin 1 inhibits tumour necrosis factor-induced apoptosis in human leukaemic cells: A possible mechanism of resistance to immune surveillance
    • Wu Y.L., Jiang X.R., Lillington D.M., Newland A.C., Kelsey S.M. Upregulation of lipocortin 1 inhibits tumour necrosis factor-induced apoptosis in human leukaemic cells: a possible mechanism of resistance to immune surveillance. Br. J. Haematol. (2000) 111 807-816.
    • (2000) Br. J. Haematol. , vol.111 , pp. 807-816
    • Wu, Y.L.1    Jiang, X.R.2    Lillington, D.M.3    Newland, A.C.4    Kelsey, S.M.5
  • 51
    • 0026500761 scopus 로고
    • Novel nucleolar and nuclear morphology in a vincristine-dependent human leukemia cell line (L100)
    • Slater L.M., Sweet P., Hsu T.C., Chan P.K. Novel nucleolar and nuclear morphology in a vincristine-dependent human leukemia cell line (L100). Exp. Cell Res. (1992) 198 170-174.
    • (1992) Exp. Cell Res. , vol.198 , pp. 170-174
    • Slater, L.M.1    Sweet, P.2    Hsu, T.C.3    Chan, P.K.4
  • 52
    • 0035578214 scopus 로고    scopus 로고
    • Accompanying protein alterations in malignant cells with a microtubule-polymerizing drug-resistance phenotype and a primary resistance mechanism
    • Poruchynsky M.S., Giannakakou P., Ward Y. et al. Accompanying protein alterations in malignant cells with a microtubule-polymerizing drug-resistance phenotype and a primary resistance mechanism. Biochem. Pharmacol. (2001) 62 1469-1480.
    • (2001) Biochem. Pharmacol. , vol.62 , pp. 1469-1480
    • Poruchynsky, M.S.1    Giannakakou, P.2    Ward, Y.3
  • 54
    • 0036111223 scopus 로고    scopus 로고
    • Comparison of protein expression profiles between monolayer and spheroid cell culture of HT-29 cells revealed fragmentation of CK18 in three-dimensional cell culture
    • Poland J., Sinha P., Siegert A., Schnolzer M., Korf U., Hauptmann S. Comparison of protein expression profiles between monolayer and spheroid cell culture of HT-29 cells revealed fragmentation of CK18 in three-dimensional cell culture. Electrophoresis (2002) 23 1174-1184.
    • (2002) Electrophoresis , vol.23 , pp. 1174-1184
    • Poland, J.1    Sinha, P.2    Siegert, A.3    Schnolzer, M.4    Korf, U.5    Hauptmann, S.6
  • 55
    • 4544282513 scopus 로고    scopus 로고
    • December
    • Protein Science Benchmarking Study. December 2001. http://www.biofind. com/business/reports/1benchmarking.pdf.
    • (2001) Protein Science Benchmarking Study
  • 56
    • 0141561891 scopus 로고    scopus 로고
    • Integrating 'omic' information: A bridge between genomics and systems biology
    • Ge H., Walhout A.J., Vidal M. Integrating 'omic' information: a bridge between genomics and systems biology. Trends Genet. (2003) 19 551-560.
    • (2003) Trends Genet. , vol.19 , pp. 551-560
    • Ge, H.1    Walhout, A.J.2    Vidal, M.3
  • 57
    • 0037337307 scopus 로고    scopus 로고
    • A systematic approach to modeling, capturing, and disseminating proteomics experimental data
    • Taylor C.F., Paton N.W., Garwood K.L. et al. A systematic approach to modeling, capturing, and disseminating proteomics experimental data. Nat. Biotechnol. (2003) 21 247-254.
    • (2003) Nat. Biotechnol. , vol.21 , pp. 247-254
    • Taylor, C.F.1    Paton, N.W.2    Garwood, K.L.3
  • 58
    • 0037079054 scopus 로고    scopus 로고
    • Computational systems biology
    • Kitano H. Computational systems biology. Nature (2002) 420 206-210.
    • (2002) Nature , vol.420 , pp. 206-210
    • Kitano, H.1
  • 59
    • 0141626866 scopus 로고    scopus 로고
    • E-Cell 2: Multi-platform E-Cell simulation system
    • Takahashi K., Ishikawa N., Sadamoto Y. et al. E-Cell 2: Multi-platform E-Cell simulation system. Bioinformatics (2003) 19 1727-1729.
    • (2003) Bioinformatics , vol.19 , pp. 1727-1729
    • Takahashi, K.1    Ishikawa, N.2    Sadamoto, Y.3


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