Thermoresponsive Polymer Nanoparticles Co-deliver RSV F Trimers with a TLR-7/8 Adjuvant

Bioconjugate Chemistry

Volumn 27, Issue 10, 2016, Pages 2372-2385

  Francica, Joseph R ^a   Lynn, Geoffrey M ^a   Laga, Richard ^b   Joyce, M Gordon ^a   Ruckwardt, Tracy J ^a   Morabito, Kaitlyn M ^a   Chen, Man ^a   Chaudhuri, Rajoshi ^c   Zhang, Baoshan ^a   Sastry, Mallika ^a   Druz, Aliaksandr ^a   Ko, Kiyoon ^a   Choe, Misook ^a   Pechar, Michal ^b   Georgiev, Ivelin S ^a   Kueltzo, Lisa A ^c   Seymour, Leonard W ^d   Mascola, John R ^a   Kwong, Peter D ^a   Graham, Barney S ^a   Seder, Robert A ^a   more..

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b INSTITUTE OF MACROMOLECULAR CHEMISTRY   (Czech Republic)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; DISEASES; EPITOPES; NANOPARTICLES; VACCINES; VIRUSES;

ANTIGENICITY; IMMUNOGENICITY; IMMUNOGENS; NEUTRALISATION; NEUTRALIZING ANTIBODIES; POLYMER NANOPARTICLES; RESPIRATORY SYNCYTIAL VIRUS; STRUCTURE-BASED; THERMORESPONSIVE POLYMER; TOLL-LIKE RECEPTORS;

OLIGOMERS;

HYBRID PROTEIN; NANOPARTICLE; NEUTRALIZING ANTIBODY; POLYMER; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; F PROTEIN, HUMAN RESPIRATORY SYNCYTIAL VIRUS; IMMUNOLOGICAL ADJUVANT; RECOMBINANT VACCINE; RESPIRATORY SYNCYTIAL VIRUS VACCINE; TLR7 PROTEIN, HUMAN; TLR8 PROTEIN, HUMAN; VIRUS FUSION PROTEIN;

ANTIBODY RESPONSE; ANTIGEN BINDING; ANTIGENICITY; ARTICLE; B LYMPHOCYTE; CIRCULAR DICHROISM; CONJUGATION; CONTROLLED STUDY; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN RESPIRATORY SYNCYTIAL VIRUS; IMMUNOGENICITY; INFLUENZA VIRUS; NONHUMAN; PHOTON CORRELATION SPECTROSCOPY; VIRION; AGONISTS; ANIMAL; CHEMISTRY; DRUG DELIVERY SYSTEM; FEMALE; IMMUNOLOGY; INBRED MOUSE STRAIN; PROCEDURES; SYNTHESIS;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, NEUTRALIZING; CHEMISTRY TECHNIQUES, SYNTHETIC; DRUG DELIVERY SYSTEMS; FEMALE; MICE, INBRED STRAINS; NANOPARTICLES; POLYMERS; RESPIRATORY SYNCYTIAL VIRUS VACCINES; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 8; VACCINES, SYNTHETIC; VIRAL FUSION PROTEINS;

EID: 84992195209     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/acs.bioconjchem.6b00370     Document Type: Article

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