-
1
-
-
32544434933
-
A preliminary evaluation of alternative adjuvants to alum using a range of established and new generation vaccine antigens
-
DOI 10.1016/j.vaccine.2005.09.046, PII S0264410X05010121
-
Singh M, Ugozzoli M, Kazzaz J et al. A preliminary evaluation of alternative adjuvants to alum using a range of established and new generation vaccine antigens. Vaccine 24(10), 1680-1686 (2006). (Pubitemid 43238245)
-
(2006)
Vaccine
, vol.24
, Issue.10
, pp. 1680-1686
-
-
Singh, M.1
Ugozzoli, M.2
Kazzaz, J.3
Chesko, J.4
Soenawan, E.5
Mannucci, D.6
Titta, F.7
Contorni, M.8
Volpini, G.9
Guidice, G.D.10
O'Hagan, D.T.11
-
2
-
-
0029177443
-
MF59 Design and evaluation of a safe and potent adjuvant for human vaccines
-
Ott G, Barchfeld GL, Chernoff D, Radhakrishnan R, van Hoogevest P, Van Nest G. MF59. Design and evaluation of a safe and potent adjuvant for human vaccines. Pharm. Biotechnol. 6, 277-296 (1995).
-
(1995)
Pharm. Biotechnol.
, vol.6
, pp. 277-296
-
-
Ott, G.1
Barchfeld, G.L.2
Chernoff, D.3
Radhakrishnan, R.4
Van Hoogevest, P.5
Van Nest, G.6
-
3
-
-
41349095198
-
Recognition of viral single-stranded RNA by Toll-like receptors
-
Diebold SS. Recognition of viral single-stranded RNA by Toll-like receptors. Adv. Drug Deliv. Rev. 60(7), 813-823 (2008).
-
(2008)
Adv. Drug Deliv. Rev.
, vol.60
, Issue.7
, pp. 813-823
-
-
Diebold, S.S.1
-
4
-
-
33845579097
-
Nucleic acid agonists for Toll-like receptor 7 are defined by the presence of uridine ribonucleotides
-
DOI 10.1002/eji.200636617
-
Diebold SS, Massacrier C, Akira S, Paturel C, Morel Y, Reis e Sousa C. Nucleic acid agonists for Toll-like receptor 7 are defined by the presence of uridine ribonucleotides. Eur. J. Immunol. 36(12), 3256-3267 (2006). (Pubitemid 44932727)
-
(2006)
European Journal of Immunology
, vol.36
, Issue.12
, pp. 3256-3267
-
-
Diebold, S.S.1
Massacrier, C.2
Akira, S.3
Paturel, C.4
Morel, Y.5
Reis E Sousa, C.6
-
5
-
-
0036008014
-
Small-antiviral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
-
DOI 10.1038/ni758
-
Hemmi H, Kaisho T, Takeuchi O et al. Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nat. Immunol. 3(2), 196-200 (2002). (Pubitemid 34141451)
-
(2002)
Nature Immunology
, vol.3
, Issue.2
, pp. 196-200
-
-
Hemmi, H.1
Kaisho, T.2
Takeuchi, O.3
Sato, S.4
Sanjo, H.5
Hoshino, K.6
Horiuchi, T.7
Tomizawa, H.8
Takeda, K.9
Akira, S.10
-
6
-
-
0036088492
-
Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848 [1]
-
DOI 10.1038/ni0602-499
-
Jurk M, Heil F, Vollmer J et al. Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848. Nat. Immunol. 3(6), 499 (2002). (Pubitemid 34669818)
-
(2002)
Nature Immunology
, vol.3
, Issue.6
, pp. 499
-
-
Jurk, M.1
Heil, F.2
Vollmer, J.3
Schetter, C.4
Krieg, A.M.5
Wagner, H.6
Lipford, G.7
Bauer, S.8
-
7
-
-
0346146996
-
Regulation of dendritic cell function through toll-like receptors
-
DOI 10.2174/1566524033479726
-
Kaisho T, Akira S. Regulation of dendritic cell function through Toll-like receptors. Curr. Mol. Med. 3(4), 373-385 (2003). (Pubitemid 36621794)
-
(2003)
Current Molecular Medicine
, vol.3
, Issue.4
, pp. 373-385
-
-
Kaisho, T.1
Akira, S.2
-
8
-
-
35748972931
-
Synthetic imidazoquinolines potently and broadly activate the cellular immune response of patients with cutaneous T-cell lymphoma: Synergy with interferon-γ enhances production of interleukin-12
-
Wysocka M, Newton S, Benoit BM et al. Synthetic imidazoquinolines potently and broadly activate the cellular immune response of patients with cutaneous T-cell lymphoma: synergy with interferon-g enhances production of interleukin-12. Clin. Lymphoma Myeloma 7(8), 524-534 (2007). (Pubitemid 350043490)
-
(2007)
Clinical Lymphoma and Myeloma
, vol.7
, Issue.8
, pp. 524-534
-
-
Wysocka, M.1
Newton, S.2
Benoit, B.M.3
Introcaso, C.4
Hancock, A.S.5
Chehimi, J.6
Richardson, S.K.7
Gelfand, J.M.8
Montaner, L.J.9
Rook, A.H.10
-
9
-
-
43049102416
-
The antiviral activity of toll-like receptor 7 and 7/8 agonists
-
DOI 10.1358/dnp.2008.21.2.1188193
-
Miller RL, Meng TC, Tomai MA. The antiviral activity of Toll-like receptor 7 and 7/8 agonists. Drug News Perspect. 21(2), 69-87 (2008). (Pubitemid 351628232)
-
(2008)
Drug News and Perspectives
, vol.21
, Issue.2
, pp. 69-87
-
-
Miller, R.L.1
Meng, T.-C.2
Tomai, M.A.3
-
10
-
-
0033543947
-
Dendritic cell maturation and subsequent enhanced T-cell stimulation induced with the novel synthetic immune response modifier R-848
-
Ahonen CL, Gibson SJ, Smith RM et al. Dendritic cell maturation and subsequent enhanced T-cell stimulation induced with the novel synthetic immune response modifier R-848. Cell. Immunol. 197(1), 62-72 (1999).
-
(1999)
Cell. Immunol.
, vol.197
, Issue.1
, pp. 62-72
-
-
Ahonen, C.L.1
Gibson, S.J.2
Smith, R.M.3
-
11
-
-
0141923686
-
Toll-like receptor ligands modulate dendritic cells to augment cytomegalovirus- and HIV-1-specific T cell responses
-
Lore K, Betts MR, Brenchley JM et al. Toll-like receptor ligands modulate dendritic cells to augment cytomegalovirus-and HIV-1-specific T cell responses. J. Immunol. 171(8), 4320-4328 (2003). (Pubitemid 37238711)
-
(2003)
Journal of Immunology
, vol.171
, Issue.8
, pp. 4320-4328
-
-
Lore, K.1
Betts, M.R.2
Brenchley, J.M.3
Kuruppu, J.4
Khojasteh, S.5
Perfetto, S.6
Roederer, M.7
Seder, R.A.8
Koup, R.A.9
-
12
-
-
9444229988
-
Shaping of adaptive immune responses to soluble proteins by TLR agonists: A role for IFN-α/β
-
DOI 10.1111/j.0818-9641.2004.01285.x
-
Durand V, Wong SY, Tough DF, Le Bon A. Shaping of adaptive immune responses to soluble proteins by TLR agonists: a role for IFN-a/b. Immunol. Cell. Biol. 82(6), 596-602 (2004). (Pubitemid 39563960)
-
(2004)
Immunology and Cell Biology
, vol.82
, Issue.6
, pp. 596-602
-
-
Durand, V.1
Wong, S.Y.C.2
Tough, D.F.3
Le Bon, A.4
-
13
-
-
34547533793
-
Additive effects of CpG ODN and R-848 as adjuvants on augmenting immune responses to HBsAg vaccination
-
DOI 10.1016/j.bbrc.2007.07.028, PII S0006291X07014957
-
Ma R, Du JL, Huang J, Wu CY. Additive effects of CpG ODN and R-848 as adjuvants on augmenting immune responses to HBsAg vaccination. Biochem. Biophys. Res. Commun. 361(2), 537-542 (2007). (Pubitemid 47187279)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.361
, Issue.2
, pp. 537-542
-
-
Ma, R.1
Du, J.-l.2
Huang, J.3
Wu, C.-y.4
-
14
-
-
0033775777
-
Adjuvant activities of immune response modifier R-848: Comparison with CpG ODN
-
Vasilakos JP, Smith RM, Gibson SJ et al. Adjuvant activities of immune response modifier R-848: comparison with CpG ODN. Cell. Immunol. 204(1), 64-74 (2000).
-
(2000)
Cell. Immunol.
, vol.204
, Issue.1
, pp. 64-74
-
-
Vasilakos, J.P.1
Smith, R.M.2
Gibson, S.J.3
-
15
-
-
20444430129
-
+ T cell responses
-
Wille-Reece U, Wu CY, Flynn BJ, Kedl RM, Seder RA. Immunization with HIV-1 Gag protein conjugated to a TLR7/8 agonist results in the generation of HIV-1 Gag-specific Th1 and CD8+ T cell responses. J. Immunol. 174(12), 7676-7683 (2005). (Pubitemid 40806272)
-
(2005)
Journal of Immunology
, vol.174
, Issue.12
, pp. 7676-7683
-
-
Wille-Reece, U.1
Wu, C.-Y.2
Flynn, B.J.3
Kedl, R.M.4
Seder, R.A.5
-
16
-
-
77955656853
-
TLR8 agonists stimulate newly recruited monocyte-derived cells into potent APCs that enhance HBsAg immunogenicity
-
Du J, Wu Z, Ren S et al. TLR8 agonists stimulate newly recruited monocyte-derived cells into potent APCs that enhance HBsAg immunogenicity. Vaccine 28(38), 6273-6281 (2010).
-
(2010)
Vaccine
, vol.28
, Issue.38
, pp. 6273-6281
-
-
Du, J.1
Wu, Z.2
Ren, S.3
-
17
-
-
1842578532
-
Resiquimod is a modest adjuvant for HIV-1 gag-based genetic immunization in a mouse model
-
DOI 10.1016/j.vaccine.2004.01.037, PII S0264410X04001021
-
Otero M, Calarota SA, Felber B et al. Resiquimod is a modest adjuvant for HIV-1 Gag-based genetic immunization in a mouse model. Vaccine 22(13-14), 1782-1790 (2004). (Pubitemid 38455417)
-
(2004)
Vaccine
, vol.22
, Issue.13-14
, pp. 1782-1790
-
-
Otero, M.1
Calarota, S.A.2
Felber, B.3
Laddy, D.4
Pavlakis, G.5
Boyer, J.D.6
Weiner, D.B.7
-
18
-
-
1842479742
-
Imiquimod and resiquimod in a mouse model: Adjuvants for DNA vaccination by particle-mediated immunotherapeutic delivery
-
DOI 10.1016/j.vaccine.2003.09.052, PII S0264410X04001045
-
Thomsen LL, Topley P, Daly MG, Brett SJ, Tite JP. Imiquimod and resiquimod in a mouse model: adjuvants for DNA vaccination by particle-mediated immunotherapeutic delivery. Vaccine 22(13-14), 1799-1809 (2004). (Pubitemid 38447228)
-
(2004)
Vaccine
, vol.22
, Issue.13-14
, pp. 1799-1809
-
-
Thomsen, L.L.1
Topley, P.2
Daly, M.G.3
Brett, S.J.4
Tite, J.P.5
-
19
-
-
26644447379
-
TLR agonists as vaccine adjuvants: Comparison of CpG ODN and Resiquimod (R-848)
-
DOI 10.1016/j.vaccine.2005.06.024, PII S0264410X05006353
-
Weeratna RD, Makinen SR, McCluskie MJ, Davis HL. TLR agonists as vaccine adjuvants: comparison of CpG ODN and Resiquimod (R-848).Vaccine 23(45), 5263-5270 (2005). (Pubitemid 41443432)
-
(2005)
Vaccine
, vol.23
, Issue.45
, pp. 5263-5270
-
-
Weeratna, R.D.1
Makinen, S.R.2
McCluskie, M.J.3
Davis, H.L.4
-
20
-
-
1642362512
-
+ T cell expansion with variable dependence on type I IFN
-
DOI 10.1084/jem.20031591
-
+ T cell expansion with variable dependence on type I IFN. J. Exp. Med. 199(6), 775-784 (2004). (Pubitemid 38375197)
-
(2004)
Journal of Experimental Medicine
, vol.199
, Issue.6
, pp. 775-784
-
-
Ahonen, C.L.1
Doxsee, C.L.2
McGurran, S.M.3
Riter, T.R.4
Wade, W.F.5
Barth, R.J.6
Vasilakos, J.P.7
Noelle, R.J.8
Kedl, R.M.9
-
21
-
-
27244443079
-
+ T cell responses in nonhuman primates
-
DOI 10.1073/pnas.0507484102
-
+ T cell responses in nonhuman primates. Proc. Natl Acad. Med. USA 102(42), 15190-15194 (2005). (Pubitemid 41513357)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.42
, pp. 15190-15194
-
-
Wille-Reece, U.1
Flynn, B.J.2
Lore, K.3
Koup, R.A.4
Kedl, R.M.5
Mattapallil, J.J.6
Weiss, W.R.7
Roederer, M.8
Seder, R.A.9
-
22
-
-
33646697743
-
Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates
-
DOI 10.1084/jem.20052433
-
Wille-Reece U, Flynn BJ, Lore K et al. Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates. J. Exp. Med. 203(5), 1249-1258 (2006). (Pubitemid 43736594)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.5
, pp. 1249-1258
-
-
Wille-Reece, U.1
Flynn, B.J.2
Lore, K.3
Koup, R.A.4
Miles, A.P.5
Saul, A.6
Kedl, R.M.7
Mattapallil, J.J.8
Weiss, W.R.9
Roederer, M.10
Seder, R.A.11
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