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Volumn 24, Issue 1, 2017, Pages 8-14

P53 on the crossroad between regeneration and cancer

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

EID: 84992094325     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2016.117     Document Type: Review
Times cited : (82)

References (116)
  • 1
    • 84984605205 scopus 로고    scopus 로고
    • Assessment of the expression, role of the alpha1 nAChR subunit in efferent cholinergic function during the development of the mammalian cochlea
    • Roux I, Wu JS, McIntosh JM, Glowatzki E. Assessment of the expression, role of the alpha1 nAChR subunit in efferent cholinergic function during the development of the mammalian cochlea. J Neurophysiol 2016; 116: 479-492.
    • (2016) J Neurophysiol , vol.116 , pp. 479-492
    • Roux, I.1    Wu, J.S.2    McIntosh, J.M.3    Glowatzki, E.4
  • 2
    • 33845602214 scopus 로고    scopus 로고
    • Apoptosis is required during early stages of tail regeneration in Xenopus laevis
    • Tseng AS, Adams DS, Qiu D, Koustubhan P, Levin M. Apoptosis is required during early stages of tail regeneration in Xenopus laevis. Dev Biol 2007; 301: 62-69.
    • (2007) Dev Biol , vol.301 , pp. 62-69
    • Tseng, A.S.1    Adams, D.S.2    Qiu, D.3    Koustubhan, P.4    Levin, M.5
  • 3
    • 79953161194 scopus 로고    scopus 로고
    • Regeneration in plants, animals: Dedifferentiation, transdifferentiation, or just differentiation?
    • Sugimoto K, Gordon SP, Meyerowitz EM. Regeneration in plants, animals: dedifferentiation, transdifferentiation, or just differentiation? Trends Cell Biol 2011; 21: 212-218.
    • (2011) Trends Cell Biol , vol.21 , pp. 212-218
    • Sugimoto, K.1    Gordon, S.P.2    Meyerowitz, E.M.3
  • 4
    • 84865641560 scopus 로고    scopus 로고
    • The role of apoptosis-induced proliferation for regeneration, cancer
    • Ryoo HD, Bergmann A. The role of apoptosis-induced proliferation for regeneration, cancer. Cold Spring Harb Perspect Biol 2012; 4: a008797.
    • (2012) Cold Spring Harb Perspect Biol , vol.4 , pp. a008797
    • Ryoo, H.D.1    Bergmann, A.2
  • 5
    • 0036417287 scopus 로고    scopus 로고
    • Inducing cellular dedifferentiation: A potential method for enhancing endogenous regeneration in mammals
    • Odelberg SJ. Inducing cellular dedifferentiation: a potential method for enhancing endogenous regeneration in mammals. Semin Cell Dev Biol 2002; 13: 335-343.
    • (2002) Semin Cell Dev Biol , vol.13 , pp. 335-343
    • Odelberg, S.J.1
  • 6
    • 0036421528 scopus 로고    scopus 로고
    • Mechanisms of muscle dedifferentiation during regeneration
    • Echeverri K, Tanaka EM. Mechanisms of muscle dedifferentiation during regeneration. Semin Cell Dev Biol 2002; 13: 353-360.
    • (2002) Semin Cell Dev Biol , vol.13 , pp. 353-360
    • Echeverri, K.1    Tanaka, E.M.2
  • 7
    • 0033173434 scopus 로고    scopus 로고
    • Molecular, cellular aspects of planarian regeneration
    • Agata K, Watanabe K. Molecular, cellular aspects of planarian regeneration. Semin Cell Dev Biol 1999; 10: 377-383.
    • (1999) Semin Cell Dev Biol , vol.10 , pp. 377-383
    • Agata, K.1    Watanabe, K.2
  • 9
    • 84902603107 scopus 로고    scopus 로고
    • Stem cell plasticity. Plasticity of epithelial stem cells in tissue regeneration
    • Blanpain C, Fuchs E. Stem cell plasticity. Plasticity of epithelial stem cells in tissue regeneration. Science 2014; 344: 1242281.
    • (2014) Science , vol.344 , pp. 1242281
    • Blanpain, C.1    Fuchs, E.2
  • 10
    • 84878240136 scopus 로고    scopus 로고
    • Molecular regulation of stem cell quiescence
    • Cheung TH, Rando TA. Molecular regulation of stem cell quiescence. Nat Rev Mol Cell Biol 2013; 14: 329-340.
    • (2013) Nat Rev Mol Cell Biol , vol.14 , pp. 329-340
    • Cheung, T.H.1    Rando, T.A.2
  • 11
    • 34247350842 scopus 로고    scopus 로고
    • Metaplasia, transdifferentiation: From pure biology to the clinic
    • Slack JM. Metaplasia, transdifferentiation: from pure biology to the clinic. Nat Rev Mol Cell Biol 2007; 8: 369-378.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 369-378
    • Slack, J.M.1
  • 12
    • 22244433866 scopus 로고    scopus 로고
    • Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+, ABCG2-cancer cells are similarly tumorigenic
    • Patrawala L, Calhoun T, Schneider-Broussard R, Zhou J, Claypool K, Tang DG. Side population is enriched in tumorigenic, stem-like cancer cells, whereas ABCG2+, ABCG2-cancer cells are similarly tumorigenic. Cancer Res 2005; 65: 6207-6219.
    • (2005) Cancer Res , vol.65 , pp. 6207-6219
    • Patrawala, L.1    Calhoun, T.2    Schneider-Broussard, R.3    Zhou, J.4    Claypool, K.5    Tang, D.G.6
  • 13
    • 2342601849 scopus 로고    scopus 로고
    • In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C
    • Yuan Y, Shen H, Franklin DS, Scadden DT, Cheng T. In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C. Nat Cell Biol 2004; 6: 436-442.
    • (2004) Nat Cell Biol , vol.6 , pp. 436-442
    • Yuan, Y.1    Shen, H.2    Franklin, D.S.3    Scadden, D.T.4    Cheng, T.5
  • 14
  • 15
    • 77954922985 scopus 로고    scopus 로고
    • Stem cells in cancer: Instigators propagators?
    • Alison MR, Islam S, Wright NA. Stem cells in cancer: instigators, propagators? J Cell Sci 2010; 123(Pt 14): 2357-2368.
    • (2010) J Cell Sci , vol.123 , pp. 2357-2368
    • Alison, M.R.1    Islam, S.2    Wright, N.A.3
  • 16
    • 9244221172 scopus 로고    scopus 로고
    • Tissue repair, stem cell renewal in carcinogenesis
    • Beachy PA, Karhadkar SS, Berman DM. Tissue repair, stem cell renewal in carcinogenesis. Nature 2004; 432: 324-331.
    • (2004) Nature , vol.432 , pp. 324-331
    • Beachy, P.A.1    Karhadkar, S.S.2    Berman, D.M.3
  • 17
    • 47749139256 scopus 로고    scopus 로고
    • Cancer as an overhealing wound: An old hypothesis revisited
    • Schafer M, Werner S. Cancer as an overhealing wound: an old hypothesis revisited. Nat Rev Mol Cell Biol 2008; 9: 628-638.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 628-638
    • Schafer, M.1    Werner, S.2
  • 19
    • 0015489740 scopus 로고
    • Molecular repair wound healing carcinogenesis: Tumor production a possible overhealing?
    • Haddow A. Molecular repair, wound healing, carcinogenesis: tumor production a possible overhealing? Adv Cancer Res 1972; 16: 181-234.
    • (1972) Adv Cancer Res , vol.16 , pp. 181-234
    • Haddow, A.1
  • 20
    • 0022891340 scopus 로고
    • Tumors: Wounds that do not heal. Similarities between tumor stroma generation, wound healing
    • Dvorak HF. Tumors: wounds that do not heal. Similarities between tumor stroma generation, wound healing. N Engl J Med 1986; 315: 1650-1659.
    • (1986) N Engl J Med , vol.315 , pp. 1650-1659
    • Dvorak, H.F.1
  • 21
    • 84878326006 scopus 로고    scopus 로고
    • Tumor suppressors: Enhancers or suppressors of regeneration?
    • Pomerantz JH, Blau HM. Tumor suppressors: enhancers or suppressors of regeneration? Development 2013; 140: 2502-2512.
    • (2013) Development , vol.140 , pp. 2502-2512
    • Pomerantz, J.H.1    Blau, H.M.2
  • 22
    • 33746907388 scopus 로고    scopus 로고
    • Cancers as wounds that do not heal: Differences, similarities between renal regeneration/repair, renal cell carcinoma
    • Riss J, Khanna C, Koo S, Chandramouli GV, Yang HH, Hu Y et al. Cancers as wounds that do not heal: differences, similarities between renal regeneration/repair, renal cell carcinoma. Cancer Res 2006; 66: 7216-7224.
    • (2006) Cancer Res , vol.66 , pp. 7216-7224
    • Riss, J.1    Khanna, C.2    Koo, S.3    Chandramouli, G.V.4    Yang, H.H.5    Hu, Y.6
  • 23
    • 0032548871 scopus 로고    scopus 로고
    • Regeneration, cancer
    • Brockes JP. Regeneration, cancer. Biochim Biophys Acta 1998; 1377: M1-M11.
    • (1998) Biochim Biophys Acta , vol.1377 , pp. M1-M11
    • Brockes, J.P.1
  • 24
    • 0030767182 scopus 로고    scopus 로고
    • Simultaneous demonstration of lens regeneration from dorsal iris, tumour production from ventral iris in the same newt eye after carcinogen administration
    • Okamoto M. Simultaneous demonstration of lens regeneration from dorsal iris, tumour production from ventral iris in the same newt eye after carcinogen administration. Differentiation 1997; 61: 285-292.
    • (1997) Differentiation , vol.61 , pp. 285-292
    • Okamoto, M.1
  • 25
    • 0027249752 scopus 로고
    • Reversal of muscle differentiation during urodele limb regeneration
    • Lo DC, Allen F, Brockes JP. Reversal of muscle differentiation during urodele limb regeneration. Proc Natl Acad Sci USA 1993; 90: 7230-7234.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 7230-7234
    • Lo, D.C.1    Allen, F.2    Brockes, J.P.3
  • 26
    • 0842346437 scopus 로고    scopus 로고
    • Principles of tumor suppression
    • Sherr CJ. Principles of tumor suppression. Cell 2004; 116: 235-246.
    • (2004) Cell , vol.116 , pp. 235-246
    • Sherr, C.J.1
  • 27
    • 0027109075 scopus 로고
    • Cancer. P53, guardian of the genome
    • Lane DP. Cancer. p53, guardian of the genome. Nature 1992; 358: 15-16.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 29
    • 70349443284 scopus 로고    scopus 로고
    • When mutants gain new powers: News from the mutant p53 field
    • Brosh R, Rotter V. When mutants gain new powers: news from the mutant p53 field. Nat Rev Cancer 2009; 9: 701-713.
    • (2009) Nat Rev Cancer , vol.9 , pp. 701-713
    • Brosh, R.1    Rotter, V.2
  • 32
    • 0036674617 scopus 로고    scopus 로고
    • Live or let die: The cell's response to p53
    • Vousden KH, Lu X. Live or let die: the cell's response to p53. Nat Rev Cancer 2002; 2: 594-604.
    • (2002) Nat Rev Cancer , vol.2 , pp. 594-604
    • Vousden, K.H.1    Lu, X.2
  • 33
    • 84905909213 scopus 로고    scopus 로고
    • Modulation of p53beta, p53gamma expression by regulating the alternative splicing of TP53 gene modifies cellular response
    • Marcel V, Fernandes K, Terrier O, Lane DP, Bourdon JC. Modulation of p53beta, p53gamma expression by regulating the alternative splicing of TP53 gene modifies cellular response. Cell Death Differ 2014; 21: 1377-1387.
    • (2014) Cell Death Differ , vol.21 , pp. 1377-1387
    • Marcel, V.1    Fernandes, K.2    Terrier, O.3    Lane, D.P.4    Bourdon, J.C.5
  • 35
    • 59949088362 scopus 로고    scopus 로고
    • P53 isoform delta113p53 is a p53 target gene that antagonizes p53 apoptotic activity via BclxL activation in zebrafish
    • Chen J, Ng SM, Chang C, Zhang Z, Bourdon JC, Lane DP et al. p53 isoform delta113p53 is a p53 target gene that antagonizes p53 apoptotic activity via BclxL activation in zebrafish. Genes Dev 2009; 23: 278-290.
    • (2009) Genes Dev , vol.23 , pp. 278-290
    • Chen, J.1    Ng, S.M.2    Chang, C.3    Zhang, Z.4    Bourdon, J.C.5    Lane, D.P.6
  • 36
    • 84938642811 scopus 로고    scopus 로고
    • P53 isoforms change p53 paradigm
    • Bourdon JC. p53 isoforms change p53 paradigm. Mol Cell Oncol 2014; 1: e969136.
    • (2014) Mol Cell Oncol , vol.1 , pp. e969136
    • Bourdon, J.C.1
  • 39
    • 78049423721 scopus 로고    scopus 로고
    • Delta40p53 controls the switch from pluripotency to differentiation by regulating IGF signaling in ESCs
    • Ungewitter E, Scrable H. Delta40p53 controls the switch from pluripotency to differentiation by regulating IGF signaling in ESCs. Genes Dev 2010; 24: 2408-2419.
    • (2010) Genes Dev , vol.24 , pp. 2408-2419
    • Ungewitter, E.1    Scrable, H.2
  • 41
    • 84886399680 scopus 로고    scopus 로고
    • Regulation of p53 is critical for vertebrate limb regeneration
    • Yun MH, Gates PB, Brockes JP. Regulation of p53 is critical for vertebrate limb regeneration. Proc Natl Acad Sci USA 2013; 110: 17392-17397.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 17392-17397
    • Yun, M.H.1    Gates, P.B.2    Brockes, J.P.3
  • 42
    • 33747176844 scopus 로고    scopus 로고
    • Compensatory proliferation in Drosophila imaginal discs requires Dronc-dependent p53 activity
    • Wells BS, Yoshida E, Johnston LA. Compensatory proliferation in Drosophila imaginal discs requires Dronc-dependent p53 activity. Curr Biol 2006; 16: 1606-1615.
    • (2006) Curr Biol , vol.16 , pp. 1606-1615
    • Wells, B.S.1    Yoshida, E.2    Johnston, L.A.3
  • 43
    • 73649143160 scopus 로고    scopus 로고
    • A planarian p53 homolog regulates proliferation, selfrenewal in adult stem cell lineages
    • Pearson BJ, Sanchez Alvarado A. A planarian p53 homolog regulates proliferation, selfrenewal in adult stem cell lineages. Development 2010; 137: 213-221.
    • (2010) Development , vol.137 , pp. 213-221
    • Pearson, B.J.1    Sanchez Alvarado, A.2
  • 45
    • 0141499228 scopus 로고    scopus 로고
    • Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS
    • Filbin MT. Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS. Nat Rev Neurosci 2003; 4: 703-713.
    • (2003) Nat Rev Neurosci , vol.4 , pp. 703-713
    • Filbin, M.T.1
  • 46
    • 70249093289 scopus 로고    scopus 로고
    • Axon regeneration in the peripheral, central nervous systems
    • Huebner EA, Strittmatter SM. Axon regeneration in the peripheral, central nervous systems. Results Probl Cell Differ 2009; 48: 339-351.
    • (2009) Results Probl Cell Differ , vol.48 , pp. 339-351
    • Huebner, E.A.1    Strittmatter, S.M.2
  • 47
    • 84864388753 scopus 로고    scopus 로고
    • Extrinsic, intrinsic determinants of nerve regeneration
    • 2041731411418392
    • Ferguson TA, Son YJ. Extrinsic, intrinsic determinants of nerve regeneration. J Tissue Eng 2011; 2: 2041731411418392.
    • (2011) J Tissue Eng , vol.2
    • Ferguson, T.A.1    Son, Y.J.2
  • 48
    • 84873608154 scopus 로고    scopus 로고
    • Mechanisms that regulate stem cell aging, life span
    • Signer RA, Morrison SJ. Mechanisms that regulate stem cell aging, life span. Cell Stem Cell 2013; 12: 152-165.
    • (2013) Cell Stem Cell , vol.12 , pp. 152-165
    • Signer, R.A.1    Morrison, S.J.2
  • 50
    • 33646782954 scopus 로고    scopus 로고
    • P53, disease: When the guardian angel fails
    • Royds JA, Iacopetta B. p53, disease: when the guardian angel fails. Cell Death Differ 2006; 13: 1017-1026.
    • (2006) Cell Death Differ , vol.13 , pp. 1017-1026
    • Royds, J.A.1    Iacopetta, B.2
  • 51
    • 77953261825 scopus 로고    scopus 로고
    • Altered longevity-assurance activity of p53:p44 in the mouse causes memory loss, neurodegeneration, premature death
    • Pehar M, O'Riordan KJ, Burns-Cusato M, Andrzejewski ME, del Alcazar CG, Burger C et al. Altered longevity-assurance activity of p53:p44 in the mouse causes memory loss, neurodegeneration, premature death. Aging Cell 2010; 9: 174-190.
    • (2010) Aging Cell , vol.9 , pp. 174-190
    • Pehar, M.1    O'Riordan, K.J.2    Burns-Cusato, M.3    Andrzejewski, M.E.4    Del Alcazar, C.G.5    Burger, C.6
  • 53
    • 33748366999 scopus 로고    scopus 로고
    • The tumor suppressor protein p53 is required for neurite outgrowth, axon regeneration
    • Di Giovanni S, Knights CD, Rao M, Yakovlev A, Beers J, Catania J et al. The tumor suppressor protein p53 is required for neurite outgrowth, axon regeneration. EMBO J 2006; 25: 4084-4096.
    • (2006) EMBO J , vol.25 , pp. 4084-4096
    • Di Giovanni, S.1    Knights, C.D.2    Rao, M.3    Yakovlev, A.4    Beers, J.5    Catania, J.6
  • 54
    • 13844276423 scopus 로고    scopus 로고
    • Noxa is a critical mediator of p53-dependent motor neuron death after nerve injury in adult mouse
    • Kiryu-Seo S, Hirayama T, Kato R, Kiyama H. Noxa is a critical mediator of p53-dependent motor neuron death after nerve injury in adult mouse. J Neurosci 2005; 25: 1442-1447.
    • (2005) J Neurosci , vol.25 , pp. 1442-1447
    • Kiryu-Seo, S.1    Hirayama, T.2    Kato, R.3    Kiyama, H.4
  • 55
    • 33745016466 scopus 로고    scopus 로고
    • The p53 family in nervous system development, disease
    • Jacobs WB, Kaplan DR, Miller FD. The p53 family in nervous system development, disease. J Neurochem 2006; 97: 1571-1584.
    • (2006) J Neurochem , vol.97 , pp. 1571-1584
    • Jacobs, W.B.1    Kaplan, D.R.2    Miller, F.D.3
  • 56
    • 38349186566 scopus 로고    scopus 로고
    • Ser18, Ser23 phosphorylation plays synergistic roles in activating p53-dependent neuronal apoptosis
    • Song J, Chao C, Xu Y. Ser18, Ser23 phosphorylation plays synergistic roles in activating p53-dependent neuronal apoptosis. Cell Cycle 2007; 6: 1412-1414.
    • (2007) Cell Cycle , vol.6 , pp. 1412-1414
    • Song, J.1    Chao, C.2    Xu, Y.3
  • 57
    • 0034529241 scopus 로고    scopus 로고
    • Mediation of nerve growth factor-driven cell cycle arrest in PC12 cells by p53. Simultaneous differentiation, proliferation subsequent to p53 functional inactivation
    • Hughes AL, Gollapudi L, Sladek TL, Neet KE. Mediation of nerve growth factor-driven cell cycle arrest in PC12 cells by p53. Simultaneous differentiation, proliferation subsequent to p53 functional inactivation. J Biol Chem 2000; 275: 37829-37837.
    • (2000) J Biol Chem , vol.275 , pp. 37829-37837
    • Hughes, A.L.1    Gollapudi, L.2    Sladek, T.L.3    Neet, K.E.4
  • 58
    • 0037151032 scopus 로고    scopus 로고
    • P38 Mitogen-activated protein kinase mediates hypoxic regulation of Mdm2 p53 in neurons
    • Zhu Y, Mao XO, Sun Y, Xia Z, Greenberg DA. p38 Mitogen-activated protein kinase mediates hypoxic regulation of Mdm2, p53 in neurons. J Biol Chem 2002; 277: 22909-22914.
    • (2002) J Biol Chem , vol.277 , pp. 22909-22914
    • Zhu, Y.1    Mao, X.O.2    Sun, Y.3    Xia, Z.4    Greenberg, D.A.5
  • 59
    • 84868142988 scopus 로고    scopus 로고
    • The nuclear events guiding successful nerve regeneration
    • Kiryu-Seo S, Kiyama H. The nuclear events guiding successful nerve regeneration. Front Mol Neurosci 2011; 4: 53.
    • (2011) Front Mol Neurosci , vol.4 , pp. 53
    • Kiryu-Seo, S.1    Kiyama, H.2
  • 60
    • 67349216689 scopus 로고    scopus 로고
    • The non-apoptotic role of p53 in neuronal biology: Enlightening the dark side of the moon
    • Tedeschi A, Di Giovanni S. The non-apoptotic role of p53 in neuronal biology: enlightening the dark side of the moon. EMBO Rep 2009; 10: 576-583.
    • (2009) EMBO Rep , vol.10 , pp. 576-583
    • Tedeschi, A.1    Di Giovanni, S.2
  • 61
    • 62849115047 scopus 로고    scopus 로고
    • A p53-CBP/p300 transcription module is required for GAP-43 expression, axon outgrowth, regeneration
    • Tedeschi A, Nguyen T, Puttagunta R, Gaub P, Di Giovanni S. A p53-CBP/p300 transcription module is required for GAP-43 expression, axon outgrowth, regeneration. Cell Death Differ 2009; 16: 543-554.
    • (2009) Cell Death Differ , vol.16 , pp. 543-554
    • Tedeschi, A.1    Nguyen, T.2    Puttagunta, R.3    Gaub, P.4    Di Giovanni, S.5
  • 62
    • 84862744950 scopus 로고    scopus 로고
    • P53-Dependent pathways in neurite outgrowth, axonal regeneration
    • Di Giovanni S, Rathore K. p53-Dependent pathways in neurite outgrowth, axonal regeneration. Cell Tissue Res 2012; 349: 87-95.
    • (2012) Cell Tissue Res , vol.349 , pp. 87-95
    • Di Giovanni, S.1    Rathore, K.2
  • 63
    • 84864281471 scopus 로고    scopus 로고
    • The histone acetyltransferase p300 promotes intrinsic axonal regeneration
    • Gaub P, Joshi Y, Wuttke A, Naumann U, Schnichels S, Heiduschka P et al. The histone acetyltransferase p300 promotes intrinsic axonal regeneration. Brain 2011; 134(Pt 7): 2134-2148.
    • (2011) Brain , vol.134 , pp. 2134-2148
    • Gaub, P.1    Joshi, Y.2    Wuttke, A.3    Naumann, U.4    Schnichels, S.5    Heiduschka, P.6
  • 64
    • 79959635553 scopus 로고    scopus 로고
    • Brain regeneration in physiology, pathology: The immune signature driving therapeutic plasticity of neural stem cells
    • Martino G, Pluchino S, Bonfanti L, Schwartz M. Brain regeneration in physiology, pathology: the immune signature driving therapeutic plasticity of neural stem cells. Physiol Rev 2011; 91: 1281-1304.
    • (2011) Physiol Rev , vol.91 , pp. 1281-1304
    • Martino, G.1    Pluchino, S.2    Bonfanti, L.3    Schwartz, M.4
  • 65
    • 58549090153 scopus 로고    scopus 로고
    • Regenerative capacity of neural precursors in the adult mammalian brain is under the control of p53
    • Medrano S, Burns-Cusato M, Atienza MB, Rahimi D, Scrable H. Regenerative capacity of neural precursors in the adult mammalian brain is under the control of p53. Neurobiol Aging 2009; 30: 483-497.
    • (2009) Neurobiol Aging , vol.30 , pp. 483-497
    • Medrano, S.1    Burns-Cusato, M.2    Atienza, M.B.3    Rahimi, D.4    Scrable, H.5
  • 66
    • 65549096948 scopus 로고    scopus 로고
    • A novel function for p53: Regulation of growth cone motility through interaction with Rho kinase
    • Qin Q, Baudry M, Liao G, Noniyev A, Galeano J, Bi X. A novel function for p53: regulation of growth cone motility through interaction with Rho kinase. J Neurosci 2009; 29: 5183-5192.
    • (2009) J Neurosci , vol.29 , pp. 5183-5192
    • Qin, Q.1    Baudry, M.2    Liao, G.3    Noniyev, A.4    Galeano, J.5    Bi, X.6
  • 67
    • 84936817243 scopus 로고    scopus 로고
    • The MDM4/MDM2-p53-IGF1 axis controls axonal regeneration, sprouting, functional recovery after CNS injury
    • Joshi Y, Soria MG, Quadrato G, Inak G, Zhou L, Hervera A et al. The MDM4/MDM2-p53-IGF1 axis controls axonal regeneration, sprouting, functional recovery after CNS injury. Brain 2015; 138(Pt 7): 1843-1862.
    • (2015) Brain , vol.138 , pp. 1843-1862
    • Joshi, Y.1    Soria, M.G.2    Quadrato, G.3    Inak, G.4    Zhou, L.5    Hervera, A.6
  • 69
    • 13444269608 scopus 로고    scopus 로고
    • Tissue repair: An important determinant of final outcome of toxicant-induced injury
    • Mehendale HM. Tissue repair: an important determinant of final outcome of toxicant-induced injury. Toxicol Pathol 2005; 33: 41-51.
    • (2005) Toxicol Pathol , vol.33 , pp. 41-51
    • Mehendale, H.M.1
  • 70
    • 84922764767 scopus 로고    scopus 로고
    • Cellular homeostasis, repair in the mammalian liver
    • Stanger BZ. Cellular homeostasis, repair in the mammalian liver. Annu Rev Physiol 2015; 77: 179-200.
    • (2015) Annu Rev Physiol , vol.77 , pp. 179-200
    • Stanger, B.Z.1
  • 71
    • 79951644393 scopus 로고    scopus 로고
    • Facultative stem cells in liver, pancreas: Fact, fancy
    • Yanger K, Stanger BZ. Facultative stem cells in liver, pancreas: fact, fancy. Dev Dyn 2011; 240: 521-529.
    • (2011) Dev Dyn , vol.240 , pp. 521-529
    • Yanger, K.1    Stanger, B.Z.2
  • 73
    • 0036808941 scopus 로고    scopus 로고
    • Cell proliferation, renewal of normal hepatocytes, bile duct cells in adult mouse liver
    • Magami Y, Azuma T, Inokuchi H, Kokuno S, Moriyasu F, Kawai K et al. Cell proliferation, renewal of normal hepatocytes, bile duct cells in adult mouse liver. Liver 2002; 22: 419-425.
    • (2002) Liver , vol.22 , pp. 419-425
    • Magami, Y.1    Azuma, T.2    Inokuchi, H.3    Kokuno, S.4    Moriyasu, F.5    Kawai, K.6
  • 74
    • 84055199890 scopus 로고    scopus 로고
    • Fate tracing of mature hepatocytes in mouse liver homeostasis, regeneration
    • Malato Y, Naqvi S, Schurmann N, Ng R, Wang B, Zape J et al. Fate tracing of mature hepatocytes in mouse liver homeostasis, regeneration. J Clin Invest 2011; 121: 4850-4860.
    • (2011) J Clin Invest , vol.121 , pp. 4850-4860
    • Malato, Y.1    Naqvi, S.2    Schurmann, N.3    Ng, R.4    Wang, B.5    Zape, J.6
  • 75
    • 84939490816 scopus 로고    scopus 로고
    • Self-renewing diploid Axin2(+) cells fuel homeostatic renewal of the liver
    • Wang B, Zhao L, Fish M, Logan CY, Nusse R. Self-renewing diploid Axin2(+) cells fuel homeostatic renewal of the liver. Nature 2015; 524: 180-185.
    • (2015) Nature , vol.524 , pp. 180-185
    • Wang, B.1    Zhao, L.2    Fish, M.3    Logan, C.Y.4    Nusse, R.5
  • 78
    • 84938743495 scopus 로고    scopus 로고
    • Hepatic progenitor cells of biliary origin with liver repopulation capacity
    • Lu WY, Bird TG, Boulter L, Tsuchiya A, Cole AM, Hay T et al. Hepatic progenitor cells of biliary origin with liver repopulation capacity. Nat Cell Biol 2015; 17: 971-983.
    • (2015) Nat Cell Biol , vol.17 , pp. 971-983
    • Lu, W.Y.1    Bird, T.G.2    Boulter, L.3    Tsuchiya, A.4    Cole, A.M.5    Hay, T.6
  • 80
    • 79958051227 scopus 로고    scopus 로고
    • Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice
    • Dorrell C, Erker L, Schug J, Kopp JL, Canaday PS, Fox AJ et al. Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice. Genes Dev 2011; 25: 1193-1203.
    • (2011) Genes Dev , vol.25 , pp. 1193-1203
    • Dorrell, C.1    Erker, L.2    Schug, J.3    Kopp, J.L.4    Canaday, P.S.5    Fox, A.J.6
  • 81
    • 33947409989 scopus 로고    scopus 로고
    • Identification of hepatocytic, bile ductular cell lineages, candidate stem cells in bipolar ductular reactions in cirrhotic human liver
    • Zhou H, Rogler LE, Teperman L, Morgan G, Rogler CE. Identification of hepatocytic, bile ductular cell lineages, candidate stem cells in bipolar ductular reactions in cirrhotic human liver. Hepatology 2007; 45: 716-724.
    • (2007) Hepatology , vol.45 , pp. 716-724
    • Zhou, H.1    Rogler, L.E.2    Teperman, L.3    Morgan, G.4    Rogler, C.E.5
  • 82
    • 84899729602 scopus 로고    scopus 로고
    • Stem/progenitor cells in liver development, homeostasis, regeneration, reprogramming
    • Miyajima A, Tanaka M, Itoh T. Stem/progenitor cells in liver development, homeostasis, regeneration, reprogramming. Cell Stem Cell 2014; 14: 561-574.
    • (2014) Cell Stem Cell , vol.14 , pp. 561-574
    • Miyajima, A.1    Tanaka, M.2    Itoh, T.3
  • 83
    • 84925092021 scopus 로고    scopus 로고
    • Adult hepatocytes are generated by self-duplication rather than stem cell differentiation
    • Yanger K, Knigin D, Zong Y, Maggs L, Gu G, Akiyama H et al. Adult hepatocytes are generated by self-duplication rather than stem cell differentiation. Cell Stem Cell 2014; 15: 340-349.
    • (2014) Cell Stem Cell , vol.15 , pp. 340-349
    • Yanger, K.1    Knigin, D.2    Zong, Y.3    Maggs, L.4    Gu, G.5    Akiyama, H.6
  • 84
    • 45549084904 scopus 로고    scopus 로고
    • Liver cancer stem cells
    • Sell S, Leffert HL. Liver cancer stem cells. J Clin Oncol 2008; 26: 2800-2805.
    • (2008) J Clin Oncol , vol.26 , pp. 2800-2805
    • Sell, S.1    Leffert, H.L.2
  • 85
    • 0036210375 scopus 로고    scopus 로고
    • Generation, characterization of p53 null transformed hepatic progenitor cells: Oval cells give rise to hepatocellular carcinoma
    • Dumble ML, Croager EJ, Yeoh GC, Quail EA. Generation, characterization of p53 null transformed hepatic progenitor cells: oval cells give rise to hepatocellular carcinoma. Carcinogenesis 2002; 23: 435-445.
    • (2002) Carcinogenesis , vol.23 , pp. 435-445
    • Dumble, M.L.1    Croager, E.J.2    Yeoh, G.C.3    Quail, E.A.4
  • 86
    • 84873712443 scopus 로고    scopus 로고
    • In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration
    • Huch M, Dorrell C, Boj SF, van Es JH, Li VS, van de Wetering M et al. In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration. Nature 2013; 494: 247-250.
    • (2013) Nature , vol.494 , pp. 247-250
    • Huch, M.1    Dorrell, C.2    Boj, S.F.3    Van Es, J.H.4    Li, V.S.5    Van De Wetering, M.6
  • 87
    • 84939216194 scopus 로고    scopus 로고
    • Hybrid periportal hepatocytes regenerate the injured liver without giving rise to cancer
    • Font-Burgada J, Shalapour S, Ramaswamy S, Hsueh B, Rossell D, Umemura A et al. Hybrid periportal hepatocytes regenerate the injured liver without giving rise to cancer. Cell 2015; 162: 766-779.
    • (2015) Cell , vol.162 , pp. 766-779
    • Font-Burgada, J.1    Shalapour, S.2    Ramaswamy, S.3    Hsueh, B.4    Rossell, D.5    Umemura, A.6
  • 88
  • 91
    • 0031052356 scopus 로고    scopus 로고
    • Regulation of cyclin-dependent kinase inhibitor p21(WAF1/Cip1/Sdi1) gene expression in hepatic regeneration
    • Albrecht JH, Meyer AH, Hu MY. Regulation of cyclin-dependent kinase inhibitor p21(WAF1/Cip1/Sdi1) gene expression in hepatic regeneration. Hepatology 1997; 25: 557-563.
    • (1997) Hepatology , vol.25 , pp. 557-563
    • Albrecht, J.H.1    Meyer, A.H.2    Hu, M.Y.3
  • 92
    • 77956627143 scopus 로고    scopus 로고
    • Direct activation of forkhead box O3 by tumor suppressors p53, p73 is disrupted during liver regeneration in mice
    • Kurinna S, Stratton SA, Tsai WW, Akdemir KC, Gu W, Singh P et al. Direct activation of forkhead box O3 by tumor suppressors p53, p73 is disrupted during liver regeneration in mice. Hepatology 2010; 52: 1023-1032.
    • (2010) Hepatology , vol.52 , pp. 1023-1032
    • Kurinna, S.1    Stratton, S.A.2    Tsai, W.W.3    Akdemir, K.C.4    Gu, W.5    Singh, P.6
  • 93
    • 84876698526 scopus 로고    scopus 로고
    • P53 regulates a mitotic transcription program, determines ploidy in normal mouse liver
    • Kurinna S, Stratton SA, Coban Z, Schumacher JM, Grompe M, Duncan AW et al. p53 regulates a mitotic transcription program, determines ploidy in normal mouse liver. Hepatology 2013; 57: 2004-2013.
    • (2013) Hepatology , vol.57 , pp. 2004-2013
    • Kurinna, S.1    Stratton, S.A.2    Coban, Z.3    Schumacher, J.M.4    Grompe, M.5    Duncan, A.W.6
  • 94
    • 33747377165 scopus 로고    scopus 로고
    • C-Jun/AP-1 controls liver regeneration by repressing p53/p21, p38 MAPK activity
    • Stepniak E, Ricci R, Eferl R, Sumara G, Sumara I, Rath M et al. c-Jun/AP-1 controls liver regeneration by repressing p53/p21, p38 MAPK activity. Genes Dev 2006; 20: 2306-2314.
    • (2006) Genes Dev , vol.20 , pp. 2306-2314
    • Stepniak, E.1    Ricci, R.2    Eferl, R.3    Sumara, G.4    Sumara, I.5    Rath, M.6
  • 96
    • 9244263076 scopus 로고    scopus 로고
    • Aneuploidy, cancer
    • Rajagopalan H, Lengauer C. Aneuploidy, cancer. Nature 2004; 432: 338-341.
    • (2004) Nature , vol.432 , pp. 338-341
    • Rajagopalan, H.1    Lengauer, C.2
  • 97
    • 80052186209 scopus 로고    scopus 로고
    • P53: Guardian of ploidy
    • Aylon Y, Oren M. p53: guardian of ploidy. Mol Oncol 2011; 5: 315-323.
    • (2011) Mol Oncol , vol.5 , pp. 315-323
    • Aylon, Y.1    Oren, M.2
  • 98
    • 66349129660 scopus 로고    scopus 로고
    • Aurora-A overexpression in mouse liver causes p53-dependent premitotic arrest during liver regeneration
    • Li CC, Chu HY, Yang CW, Chou CK, Tsai TF. Aurora-A overexpression in mouse liver causes p53-dependent premitotic arrest during liver regeneration. Mol Cancer Res 2009; 7: 678-688.
    • (2009) Mol Cancer Res , vol.7 , pp. 678-688
    • Li, C.C.1    Chu, H.Y.2    Yang, C.W.3    Chou, C.K.4    Tsai, T.F.5
  • 100
    • 84872919631 scopus 로고    scopus 로고
    • Complexity of cancer stem cells
    • Sugihara E, Saya H. Complexity of cancer stem cells. Int J Cancer 2013; 132: 1249-1259.
    • (2013) Int J Cancer , vol.132 , pp. 1249-1259
    • Sugihara, E.1    Saya, H.2
  • 101
    • 84991325551 scopus 로고    scopus 로고
    • Oncogenic mutant p53 gain of function nourishes the vicious cycle of tumor development, cancer stem-cell formation
    • Shetzer Y, Molchadsky A, Rotter V. Oncogenic mutant p53 gain of function nourishes the vicious cycle of tumor development, cancer stem-cell formation. Cold Spring Harb Perspect Med 2016; 6: a026203.
    • (2016) Cold Spring Harb Perspect Med , vol.6 , pp. a026203
    • Shetzer, Y.1    Molchadsky, A.2    Rotter, V.3
  • 102
    • 0037067656 scopus 로고    scopus 로고
    • P53: Good cop/bad cop
    • Sharpless NE, DePinho RA. p53: good cop/bad cop. Cell 2002; 110: 9-12.
    • (2002) Cell , vol.110 , pp. 9-12
    • Sharpless, N.E.1    Depinho, R.A.2
  • 106
    • 84859966322 scopus 로고    scopus 로고
    • The cell biology of regeneration
    • King RS, Newmark PA. The cell biology of regeneration. J Cell Biol 2012; 196: 553-562.
    • (2012) J Cell Biol , vol.196 , pp. 553-562
    • King, R.S.1    Newmark, P.A.2
  • 107
    • 34548130839 scopus 로고    scopus 로고
    • Transgenic stem cells in Hydra reveal an early evolutionary origin for key elements controlling selfrenewal, differentiation
    • Khalturin K, Anton-Erxleben F, Milde S, Plotz C, Wittlieb J, Hemmrich G et al. Transgenic stem cells in Hydra reveal an early evolutionary origin for key elements controlling selfrenewal, differentiation. Dev Biol 2007; 309: 32-44.
    • (2007) Dev Biol , vol.309 , pp. 32-44
    • Khalturin, K.1    Anton-Erxleben, F.2    Milde, S.3    Plotz, C.4    Wittlieb, J.5    Hemmrich, G.6
  • 108
    • 37349016028 scopus 로고    scopus 로고
    • Cell type complexity in the basal metazoan Hydra is maintained by both stem cell based mechanisms, transdifferentiation
    • Siebert S, Anton-Erxleben F, Bosch TC. Cell type complexity in the basal metazoan Hydra is maintained by both stem cell based mechanisms, transdifferentiation. Dev Biol 2008; 313: 13-24.
    • (2008) Dev Biol , vol.313 , pp. 13-24
    • Siebert, S.1    Anton-Erxleben, F.2    Bosch, T.C.3
  • 109
    • 0024415592 scopus 로고
    • Effects of activators, antagonists of the neuropeptides substance P, substance K on cell proliferation in planarians
    • Baguna J, Salo E, Romero R. Effects of activators, antagonists of the neuropeptides substance P, substance K on cell proliferation in planarians. Int J Dev Biol 1989; 33: 261-266.
    • (1989) Int J Dev Biol , vol.33 , pp. 261-266
    • Baguna, J.1    Salo, E.2    Romero, R.3
  • 110
    • 79955985703 scopus 로고    scopus 로고
    • Clonogenic neoblasts are pluripotent adult stem cells that underlie planarian regeneration
    • Wagner DE, Wang IE, Reddien PW. Clonogenic neoblasts are pluripotent adult stem cells that underlie planarian regeneration. Science 2011; 332: 811-816.
    • (2011) Science , vol.332 , pp. 811-816
    • Wagner, D.E.1    Wang, I.E.2    Reddien, P.W.3
  • 112
    • 77950200829 scopus 로고    scopus 로고
    • Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation, proliferation
    • Jopling C, Sleep E, Raya M, Marti M, Raya A, Izpisua Belmonte JC. Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation, proliferation. Nature 2010; 464: 606-609.
    • (2010) Nature , vol.464 , pp. 606-609
    • Jopling, C.1    Sleep, E.2    Raya, M.3    Marti, M.4    Raya, A.5    Izpisua Belmonte, J.C.6
  • 114
    • 78650204195 scopus 로고    scopus 로고
    • Molecular, cellular aspects of amphibian lens regeneration
    • Henry JJ, Tsonis PA. Molecular, cellular aspects of amphibian lens regeneration. Prog Retin Eye Res 2010; 29: 543-555.
    • (2010) Prog Retin Eye Res , vol.29 , pp. 543-555
    • Henry, J.J.1    Tsonis, P.A.2
  • 115
    • 19344366751 scopus 로고    scopus 로고
    • The regenerative plasticity of isolated urodele myofibers, its dependence on MSX1
    • Kumar A, Velloso CP, Imokawa Y, Brockes JP. The regenerative plasticity of isolated urodele myofibers, its dependence on MSX1. PLoS Biol 2004; 2: E218.
    • (2004) PLoS Biol , vol.2 , pp. E218
    • Kumar, A.1    Velloso, C.P.2    Imokawa, Y.3    Brockes, J.P.4
  • 116
    • 31944437075 scopus 로고    scopus 로고
    • Salamander limb regeneration involves the activation of a multipotent skeletal muscle satellite cell population
    • Morrison JI, Loof S, He P, Simon A. Salamander limb regeneration involves the activation of a multipotent skeletal muscle satellite cell population. J Cell Biol 2006; 172: 433-440.
    • (2006) J Cell Biol , vol.172 , pp. 433-440
    • Morrison, J.I.1    Loof, S.2    He, P.3    Simon, A.4


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