P53 isoform Δ113p53 is a p53 target gene that antagonizes p53 apoptotic activity via BclxL activation in zebrafish

Genes and Development

Volumn 23, Issue 3, 2009, Pages 278-290

  Chen, Jun ^a   Ng, Sok Meng ^a   Chang, Qing ^a   Zhang, Zhenhai ^a   Bourdon, Jean Christophe ^b   Lane, David P ^a,b   Peng, Jinrong ^a  

^a INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

113p53; Apoptosis; Bcl2; P53 isoforms; Zebrafish

Indexed keywords

CAMPTOTHECIN; DELTA113P53 PROTEIN; GENOMIC DNA; MESSENGER RNA; PLASMID DNA; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MDM2; PROTEIN P53; RNA 18S; ROSCOVITINE; UNCLASSIFIED DRUG; BCL2L PROTEIN, ZEBRAFISH; DNA; ISOPROTEIN; PROTEIN BCL X; ZEBRAFISH PROTEIN;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA DAMAGE; EMBRYO; GAMMA IRRADIATION; GENE LOCUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC ANIMAL; TUMOR SUPPRESSOR GENE; ZEBRA FISH; ANIMAL; BIOLOGICAL MODEL; CYTOLOGY; DIGESTIVE SYSTEM; FEEDBACK SYSTEM; GENE DELETION; GENETICS; METABOLISM; PHYSIOLOGY; PRENATAL DEVELOPMENT; RADIATION DOSE; REPORTER GENE; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

DANIO RERIO;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; APOPTOSIS; BASE SEQUENCE; BCL-X PROTEIN; DIGESTIVE SYSTEM; DNA; DNA DAMAGE; FEEDBACK, BIOCHEMICAL; GENES, P53; GENES, REPORTER; MODELS, BIOLOGICAL; PROMOTER REGIONS, GENETIC; PROTEIN ISOFORMS; RADIATION TOLERANCE; RNA, MESSENGER; SEQUENCE DELETION; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION; TUMOR SUPPRESSOR PROTEIN P53; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 59949088362     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1761609     Document Type: Article

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