-
1
-
-
84860835430
-
Pulmonary embolism and deep vein thrombosis
-
Goldhaber SZ, Bounameaux H. Pulmonary embolism and deep vein thrombosis. Lancet 2012;379:1835-46.
-
(2012)
Lancet
, vol.379
, pp. 1835-1846
-
-
Goldhaber, S.Z.1
Bounameaux, H.2
-
2
-
-
79951568921
-
Old and new anticoagulant drugs: A minireview
-
Mannucci PM, Franchini M. Old and new anticoagulant drugs: a minireview. Ann Med 2011;43:116-23.
-
(2011)
Ann Med
, vol.43
, pp. 116-123
-
-
Mannucci, P.M.1
Franchini, M.2
-
5
-
-
84869095094
-
New anticoagulants for treatment of venous thromboembolism
-
Franchini M, Mannucci PM. New anticoagulants for treatment of venous thromboembolism. Eur J Intern Med 2012;23:692-5.
-
(2012)
Eur J Intern Med
, vol.23
, pp. 692-695
-
-
Franchini, M.1
Mannucci, P.M.2
-
6
-
-
84856784474
-
Oral anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
-
Ageno W, Gallus AS, Wittkowsky A, et al; American College of Chest Physicians. Oral anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012;141(2 Suppl):e44S-88S.
-
(2012)
Chest
, vol.141
, Issue.2
, pp. e44S-e88S
-
-
American College of Chest Physicians1
Ageno, W.2
Gallus, A.S.3
Wittkowsky, A.4
-
7
-
-
84856776395
-
New antithrombotic drugs: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
-
Weitz JI, Eikelboom JW, Samama MM; American College of Chest Physicians. New antithrombotic drugs: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012;141(2 Suppl):e120S-51S.
-
(2012)
Chest
, vol.141
, Issue.2
, pp. e120S-e151S
-
-
American College of Chest Physicians1
Weitz, J.I.2
Eikelboom, J.W.3
Samama, M.M.4
-
8
-
-
35449007749
-
Oral dabigatran etexilate vs. Subcutaneous enoxaparin for the prevention of venous thromboembolism after total knee replacement: The REMODEL randomized trial
-
Eriksson BI, Dahl OE, Rosencher N, et al. Oral dabigatran etexilate vs. subcutaneous enoxaparin for the prevention of venous thromboembolism after total knee replacement: the REMODEL randomized trial. J Thromb Haemost 2007;5:2178-85.
-
(2007)
J Thromb Haemost
, vol.5
, pp. 2178-2185
-
-
Eriksson, B.I.1
Dahl, O.E.2
Rosencher, N.3
-
9
-
-
34548575058
-
Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: A randomised, double-blind, non-inferiority trial
-
Eriksson BI, Dahl OE, Rosencher N, et al. Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: a randomised, double-blind, non-inferiority trial. Lancet 2007;370:949-56.
-
(2007)
Lancet
, vol.370
, pp. 949-956
-
-
Eriksson, B.I.1
Dahl, O.E.2
Rosencher, N.3
-
10
-
-
71849117615
-
Dabigatran versus warfarin in the treatment of acute venous thromboembolism
-
Schulman S, Kearon C, Kakkar AK, et al. Dabigatran versus warfarin in the treatment of acute venous thromboembolism. N Engl J Med 2009;361:2342-52.
-
(2009)
N Engl J Med
, vol.361
, pp. 2342-2352
-
-
Schulman, S.1
Kearon, C.2
Kakkar, A.K.3
-
11
-
-
70349306707
-
Dabigatran versus warfarin in patients with atrial fibrillation
-
Connolly SJ, Ezekowitz MD, Yusuf S, et al. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 2009;361:1139-51.
-
(2009)
N Engl J Med
, vol.361
, pp. 1139-1151
-
-
Connolly, S.J.1
Ezekowitz, M.D.2
Yusuf, S.3
-
12
-
-
68249158084
-
Apixaban or enoxaparin for thromboprophylaxis after knee replacement
-
Lassen MR, Raskob GE, Gallus A, et al. Apixaban or enoxaparin for thromboprophylaxis after knee replacement. N Engl J Med 2009;361:594-604.
-
(2009)
N Engl J Med
, vol.361
, pp. 594-604
-
-
Lassen, M.R.1
Raskob, G.E.2
Gallus, A.3
-
13
-
-
78650587760
-
Apixaban versus enoxaparin for thromboprophylaxis after hip replacement
-
Lassen MR, Gallus A, Raskob GE, et al. Apixaban versus enoxaparin for thromboprophylaxis after hip replacement. N Engl J Med 2010;363:2487-98.
-
(2010)
N Engl J Med
, vol.363
, pp. 2487-2498
-
-
Lassen, M.R.1
Gallus, A.2
Raskob, G.E.3
-
14
-
-
84880327613
-
Oral apixaban for the treatment of acute venous thromboembolism
-
Agnelli G, Buller HR, Cohen A, et al. Oral apixaban for the treatment of acute venous thromboembolism. N Engl J Med 2013;369:799-808.
-
(2013)
N Engl J Med
, vol.369
, pp. 799-808
-
-
Agnelli, G.1
Buller, H.R.2
Cohen, A.3
-
15
-
-
80052825103
-
Apixaban versus warfarin in patients with atrial fibrillation
-
Granger CB, Alexander JH, McMurray JJ, et al. Apixaban versus warfarin in patients with atrial fibrillation. N Engl J Med 2011;365:981-92.
-
(2011)
N Engl J Med
, vol.365
, pp. 981-992
-
-
Granger, C.B.1
Alexander, J.H.2
McMurray, J.J.3
-
16
-
-
84916225564
-
Safety and efficacy of edoxaban, an oral factor Xa inhibitor, versus enoxaparin for thromboprophylaxis after total knee arthroplasty: The STARS E-3 trial
-
Fuji T, Wang CJ, Fujita S, et al. Safety and efficacy of edoxaban, an oral factor Xa inhibitor, versus enoxaparin for thromboprophylaxis after total knee arthroplasty: the STARS E-3 trial. Thromb Res 2014;134:1198-204.
-
(2014)
Thromb Res
, vol.134
, pp. 1198-1204
-
-
Fuji, T.1
Wang, C.J.2
Fujita, S.3
-
17
-
-
84912535162
-
Safety and efficacy of edoxaban, an oral factor Xa inhibitor, for thromboprophylaxis after total hip arthroplasty in Japan and Taiwan
-
Fuji T, Wang CJ, Fujita S, et al. Safety and efficacy of edoxaban, an oral factor Xa inhibitor, for thromboprophylaxis after total hip arthroplasty in Japan and Taiwan. J Arthroplasty 2014;29:2439-46.
-
(2014)
J Arthroplasty
, vol.29
, pp. 2439-2446
-
-
Fuji, T.1
Wang, C.J.2
Fujita, S.3
-
18
-
-
84885618705
-
Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism
-
Hokusai-VTE Investigators; Büller HR, Décousus H, Grosso MA, et al. Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism. N Engl J Med 2013;369:1406-15.
-
(2013)
N Engl J Med
, vol.369
, pp. 1406-1415
-
-
Büller, H.R.1
Décousus, H.2
Grosso, M.A.3
-
19
-
-
84888362796
-
Edoxaban versus warfarin in patients with atrial fibrillation
-
Giugliano RP, Ruff CT, Braunwald E, et al; ENGAGE AFTIMI 48 Investigators. Edoxaban versus warfarin in patients with atrial fibrillation. N Engl J Med 2013;369:2093-104.
-
(2013)
N Engl J Med
, vol.369
, pp. 2093-2104
-
-
Giugliano, R.P.1
Ruff, C.T.2
Braunwald, E.3
-
20
-
-
45949099359
-
Rivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty
-
Eriksson BI, Borris LC, Friedman RJ, et al. Rivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty. N Engl J Med 2008;358:2765-75.
-
(2008)
N Engl J Med
, vol.358
, pp. 2765-2775
-
-
Eriksson, B.I.1
Borris, L.C.2
Friedman, R.J.3
-
21
-
-
45949103416
-
Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty
-
Lassen MR, Ageno W, Borris LC, et al. Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty. N Engl J Med 2008;358:2776-86.
-
(2008)
N Engl J Med
, vol.358
, pp. 2776-2786
-
-
Lassen, M.R.1
Ageno, W.2
Borris, L.C.3
-
22
-
-
78650619315
-
Oral rivaroxaban for symptomatic venous thromboembolism
-
The EINSTEIN Investigators. Oral rivaroxaban for symptomatic venous thromboembolism. N Engl J Med 2010;363:2499-510.
-
(2010)
N Engl J Med
, vol.363
, pp. 2499-2510
-
-
-
23
-
-
80052592404
-
Rivaroxaban versus warfarin in nonvalvular atrial fibrillation
-
Patel MR, Mahaffey KW, Garg J, et al; ROCKET AF Investigators. Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. N Engl J Med 2011;365:883-91.
-
(2011)
N Engl J Med
, vol.365
, pp. 883-891
-
-
Patel, M.R.1
Mahaffey, K.W.2
Garg, J.3
-
24
-
-
79955747887
-
The practical management of intracerebral hemorrhage associated with oral anticoagulant therapy
-
Masotti L, Di Napoli M, Godoy DA, et al. The practical management of intracerebral hemorrhage associated with oral anticoagulant therapy. Int J Stroke 2011;6:228-40.
-
(2011)
Int J Stroke
, vol.6
, pp. 228-240
-
-
Masotti, L.1
Di Napoli, M.2
Godoy, D.A.3
-
25
-
-
84861173947
-
Reversal of drug-induce anticoagulation: Old solutions and new problems
-
Dzik WS. Reversal of drug-induce anticoagulation: old solutions and new problems. Transfusion 2012;52:45S-55S.
-
(2012)
Transfusion
, vol.52
, pp. 45S-55S
-
-
Dzik, W.S.1
-
26
-
-
84867240886
-
New direct oral anticoagulants - Current therapeutic options and treatment recommendations for bleeding complications
-
Miesbach W, Seifried E. New direct oral anticoagulants - current therapeutic options and treatment recommendations for bleeding complications. Thromb Haemost 2012;108:625-32.
-
(2012)
Thromb Haemost
, vol.108
, pp. 625-632
-
-
Miesbach, W.1
Seifried, E.2
-
27
-
-
84897895391
-
How I treat targetspecific oral anticoagulant-associated bleeding
-
Siegal DM, Garcia DA, Crowther MA. How I treat targetspecific oral anticoagulant-associated bleeding. Blood 2014;123:1152-8.
-
(2014)
Blood
, vol.123
, pp. 1152-1158
-
-
Siegal, D.M.1
Garcia, D.A.2
Crowther, M.A.3
-
28
-
-
84943601987
-
Management of bleeding associated with new oral anticoagulants
-
Franchini M, Bonfanti C, Mannucci PM. Management of bleeding associated with new oral anticoagulants. Semin Thromb Hemost 2015;41:788-801.
-
(2015)
Semin Thromb Hemost
, vol.41
, pp. 788-801
-
-
Franchini, M.1
Bonfanti, C.2
Mannucci, P.M.3
-
29
-
-
84896830370
-
Metaanalysis of randomized controlled trials on the risk of bleeding with dabigatran
-
Bloom BJ, Filion KB, Atallah R, Eisenberg MJ. Metaanalysis of randomized controlled trials on the risk of bleeding with dabigatran. Am J Cardiol 2014;113:1066-74.
-
(2014)
Am J Cardiol
, vol.113
, pp. 1066-1074
-
-
Bloom, B.J.1
Filion, K.B.2
Atallah, R.3
Eisenberg, M.J.4
-
30
-
-
84863981277
-
Meta-analysis of efficacy and safety of new oral anticoagulants (dabigatran, rivaroxaban, apixaban) versus warfarin in patients with atrial fibrillation
-
Miller CS, Grandi SM, Shimony A, et al. Meta-analysis of efficacy and safety of new oral anticoagulants (dabigatran, rivaroxaban, apixaban) versus warfarin in patients with atrial fibrillation. Am J Cardiol 2012;110:453-60.
-
(2012)
Am J Cardiol
, vol.110
, pp. 453-460
-
-
Miller, C.S.1
Grandi, S.M.2
Shimony, A.3
-
31
-
-
84869236631
-
Efficacy and safety of the novel oral anticoagulants in atrial fibrillation: A systematic review and meta-analysis of the literature
-
Dentali F, Riva N, Crowther M, et al. Efficacy and safety of the novel oral anticoagulants in atrial fibrillation: a systematic review and meta-analysis of the literature. Circulation 2012;126:2381-91.
-
(2012)
Circulation
, vol.126
, pp. 2381-2391
-
-
Dentali, F.1
Riva, N.2
Crowther, M.3
-
32
-
-
84873059447
-
Bleeding of new oral anticoagulants for stroke prevention in atrial fibrillation: A meta-analysis of randomized controlled trials
-
Kwong JS, Lam YY, Yan BP, Yu CM. Bleeding of new oral anticoagulants for stroke prevention in atrial fibrillation: a meta-analysis of randomized controlled trials. Cardiovasc Drugs Ther 2013;27:23-35.
-
(2013)
Cardiovasc Drugs Ther
, vol.27
, pp. 23-35
-
-
Kwong, J.S.1
Lam, Y.Y.2
Yan, B.P.3
Yu, C.M.4
-
33
-
-
84896117299
-
Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: A meta-analysis of randomised trials
-
Ruff CT, Giugliano RP, Braunwald E, et al. Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials. Lancet 2014;383:955-62.
-
(2014)
Lancet
, vol.383
, pp. 955-962
-
-
Ruff, C.T.1
Giugliano, R.P.2
Braunwald, E.3
-
34
-
-
84869838484
-
Efficacy and safety of novel oral anticoagulants for treatment of acute venous thromboembolism: Direct and adjusted indirect meta-analysis of randomised controlled trials
-
Fox BD, Kahn SR, Langleben D, et al. Efficacy and safety of novel oral anticoagulants for treatment of acute venous thromboembolism: direct and adjusted indirect meta-analysis of randomised controlled trials. BMJ 2012;345:e7498.
-
(2012)
BMJ
, vol.345
, pp. e7498
-
-
Fox, B.D.1
Kahn, S.R.2
Langleben, D.3
-
35
-
-
84896741977
-
Effectiveness and safety of novel oral anticoagulants as compared with Vitamin K antagonists in the treatment of acute symptomatic venous thromboembolism: A systematic review and metaanalysis
-
van der Hulle T, Kooiman J, den Exter PL, et al. Effectiveness and safety of novel oral anticoagulants as compared with vitamin K antagonists in the treatment of acute symptomatic venous thromboembolism: a systematic review and metaanalysis. J Thromb Haemost 2014;12:320-8.
-
(2014)
J Thromb Haemost
, vol.12
, pp. 320-328
-
-
Van Der Hulle, T.1
Kooiman, J.2
Den Exter, P.L.3
-
36
-
-
84907662267
-
The impact of bleeding complications in patients receiving target-specific oral anticoagulants: A systematic review and meta-analysis
-
Chai-Adisaksopha C, Crowther M, Isayama T, Lim W. The impact of bleeding complications in patients receiving target-specific oral anticoagulants: a systematic review and meta-analysis. Blood 2014;124:2450-8.
-
(2014)
Blood
, vol.124
, pp. 2450-2458
-
-
Chai-Adisaksopha, C.1
Crowther, M.2
Isayama, T.3
Lim, W.4
-
37
-
-
84868523625
-
2012 focused update of the ESC Guidelines for the management of atrial fibrillation: An update of the 2010 ESC Guidelines for the management of atrial fibrillation. Developed with the special contribution of the European Heart Rhythm Association
-
Camm AJ, Lip GY, De Caterina R, et al.; ESC Committee for Practice Guidelines (CPG). 2012 focused update of the ESC Guidelines for the management of atrial fibrillation: an update of the 2010 ESC Guidelines for the management of atrial fibrillation. Developed with the special contribution of the European Heart Rhythm Association. Eur Heart J 2012;33:2719-47.
-
(2012)
Eur Heart J
, vol.33
, pp. 2719-2747
-
-
ESC Committee for Practice Guidelines (CPG)1
Camm, A.J.2
Lip, G.Y.3
De Caterina, R.4
-
38
-
-
84927557449
-
The use of novel oral anticoagulants: The debate continues!
-
Franchini M, Velati C. The use of novel oral anticoagulants: the debate continues! Blood Transfus 2015;13:170-1.
-
(2015)
Blood Transfus
, vol.13
, pp. 170-171
-
-
Franchini, M.1
Velati, C.2
-
39
-
-
84927510114
-
Which patients with venous thromboembolism should receive non-Vitamin K antagonist oral anticoagulants? The majority
-
Riva N, Ageno W. Which patients with venous thromboembolism should receive non-vitamin K antagonist oral anticoagulants? The majority. Blood Transfus 2015;13:181-3.
-
(2015)
Blood Transfus
, vol.13
, pp. 181-183
-
-
Riva, N.1
Ageno, W.2
-
40
-
-
84927518854
-
The treatment of venous thromboembolism with novel oral anticoagulants: Warnings and limitations
-
Prandoni P. The treatment of venous thromboembolism with novel oral anticoagulants: warnings and limitations. Blood Transfus 2015;13:178-80.
-
(2015)
Blood Transfus
, vol.13
, pp. 178-180
-
-
Prandoni, P.1
-
41
-
-
84878292470
-
Efficacy and safety of dabigatran etexilate and warfarin in "real-world" patients with atrial fibrillation: A prospective nationwide cohort study
-
Larsen TB, Rasmussen LH, Skjøth F, et al. Efficacy and safety of dabigatran etexilate and warfarin in "real-world" patients with atrial fibrillation: a prospective nationwide cohort study. J Am Coll Cardiol 2013;61:2264-73.
-
(2013)
J Am Coll Cardiol
, vol.61
, pp. 2264-2273
-
-
Larsen, T.B.1
Rasmussen, L.H.2
Skjøth, F.3
-
42
-
-
84924034859
-
Cardiovascular, bleeding, and mortality risks in elderly Medicare patients treated with dabigatran or warfarin for non-valvular atrial fibrillation
-
Graham DJ, Reichman ME, Wernecke M, et al. Cardiovascular, bleeding, and mortality risks in elderly Medicare patients treated with dabigatran or warfarin for non-valvular atrial fibrillation. Circulation 2015;131:157-64.
-
(2015)
Circulation
, vol.131
, pp. 157-164
-
-
Graham, D.J.1
Reichman, M.E.2
Wernecke, M.3
-
43
-
-
84949115444
-
Risk of gastrointestinal bleeding associated with oral anticoagulants: Population based retrospective cohort study
-
Chang HY, Zhou M, Tang W, et al. Risk of gastrointestinal bleeding associated with oral anticoagulants: population based retrospective cohort study. BMJ 2015;350:h1585.
-
(2015)
BMJ
, vol.350
, pp. h1585
-
-
Chang, H.Y.1
Zhou, M.2
Tang, W.3
-
44
-
-
84930654339
-
Comparative risk of gastrointestinal bleeding with dabigatran, rivaroxaban, and warfarin: Population based cohort study
-
Abraham NS, Singh S, Alexander GC, et al. Comparative risk of gastrointestinal bleeding with dabigatran, rivaroxaban, and warfarin: population based cohort study. BMJ 2015;350:h1857.
-
(2015)
BMJ
, vol.350
, pp. h1857
-
-
Abraham, N.S.1
Singh, S.2
Alexander, G.C.3
-
45
-
-
84905747093
-
Rates, management, and outcome of rivaroxaban bleeding in daily care: Results from the Dresden NOAC registry
-
Beyer-Westendorf J, Förster K, Pannach S, et al. Rates, management, and outcome of rivaroxaban bleeding in daily care: results from the Dresden NOAC registry. Blood 2014;124:955-62.
-
(2014)
Blood
, vol.124
, pp. 955-962
-
-
Beyer-Westendorf, J.1
Förster, K.2
Pannach, S.3
-
46
-
-
84922432396
-
Pattern and management of bleeding complications with new oral anticoagulants. Results of the prospective Dresden NOAC Registry (NCT01588119) [Abstract]
-
Beyer-Westendorf J. Pattern and management of bleeding complications with new oral anticoagulants. Results of the prospective Dresden NOAC Registry (NCT01588119) [Abstract]. J Thromb Haemost 2013;11:774.
-
(2013)
J Thromb Haemost
, vol.11
, pp. 774
-
-
Beyer-Westendorf, J.1
-
47
-
-
84903135364
-
New oral anticoagulants: Clinical indications, monitoring and treatment of acute bleeding complications
-
Fenger-Eriksen C, Münster AM, Grove EL. New oral anticoagulants: clinical indications, monitoring and treatment of acute bleeding complications. Acta Anaesthesiol Scand 2014;58:651-9.
-
(2014)
Acta Anaesthesiol Scand
, vol.58
, pp. 651-659
-
-
Fenger-Eriksen, C.1
Münster, A.M.2
Grove, E.L.3
-
48
-
-
84879528916
-
Assessment of anticoagulation intensity and management of bleeding with old and new oral anticoagulants
-
Liew A, Eikelboom JW, O'Donnell M, Hart RG. Assessment of anticoagulation intensity and management of bleeding with old and new oral anticoagulants. Can J Cardiol 2013;29:S34-44.
-
(2013)
Can J Cardiol
, vol.29
, pp. S34-S44
-
-
Liew, A.1
Eikelboom, J.W.2
O'Donnell, M.3
Hart, R.G.4
-
49
-
-
84876681725
-
Reversal of novel oral anticoagulants in patients with major bleeding
-
Siegal DM, Cuker A. Reversal of novel oral anticoagulants in patients with major bleeding. J Thromb Thrombolysis 2013;35:391-8.
-
(2013)
J Thromb Thrombolysis
, vol.35
, pp. 391-398
-
-
Siegal, D.M.1
Cuker, A.2
-
50
-
-
66349097846
-
Recommendations for the transfusion of plasma and platelets
-
Liumbruno G, Bennardello F, Lattanzio A, et al. Recommendations for the transfusion of plasma and platelets. Blood Transfus 2009;7:132-50.
-
(2009)
Blood Transfus
, vol.7
, pp. 132-150
-
-
Liumbruno, G.1
Bennardello, F.2
Lattanzio, A.3
-
51
-
-
73449135164
-
Recommendations for the use of antithrombin concentrates and prothrombin complex concentrates
-
Liumbruno G, Bennardello F, Lattanzio A, et al. Recommendations for the use of antithrombin concentrates and prothrombin complex concentrates. Blood Transfus 2009;7:325-34.
-
(2009)
Blood Transfus
, vol.7
, pp. 325-334
-
-
Liumbruno, G.1
Bennardello, F.2
Lattanzio, A.3
-
52
-
-
78751505594
-
Recommendations for the transfusion management of patients in the peri-operative period. I. The pre-operative period
-
Liumbruno GM, Bennardello F, Lattanzio A, et al. Recommendations for the transfusion management of patients in the peri-operative period. I. The pre-operative period. Blood Transfus 2011;9:19-40.
-
(2011)
Blood Transfus
, vol.9
, pp. 19-40
-
-
Liumbruno, G.M.1
Bennardello, F.2
Lattanzio, A.3
-
53
-
-
84885574861
-
Clinical use and the Italian demand for prothrombin complex concentrates
-
Franchini M, Liumbruno GM, Lanzoni M, et al. Clinical use and the Italian demand for prothrombin complex concentrates. Blood Transfus 2013;11(4 Suppl):s94-100.
-
(2013)
Blood Transfus
, vol.11
, Issue.4
, pp. s94-s100
-
-
Franchini, M.1
Liumbruno, G.M.2
Lanzoni, M.3
-
54
-
-
84929240506
-
Anticoagulation reversal in the era of the non-Vitamin K oral anticoagulants
-
Enriquez A, Lip GY, Baranchuk A. Anticoagulation reversal in the era of the non-vitamin K oral anticoagulants. EP Europace 2015; euv030.
-
(2015)
EP Europace
, pp. euv030
-
-
Enriquez, A.1
Lip, G.Y.2
Baranchuk, A.3
-
55
-
-
84923445520
-
Recent advances in the development of specific antidotes for target-specific oral anticoagulants
-
Mo Y, Yam FK. Recent advances in the development of specific antidotes for target-specific oral anticoagulants. Pharmacotherapy 2015;35:198-207.
-
(2015)
Pharmacotherapy
, vol.35
, pp. 198-207
-
-
Mo, Y.1
Yam, F.K.2
-
56
-
-
84992114385
-
-
Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals Inc.;, Accessed on 08/07/2015
-
PRADAXA (dabigatran etexilate mesylate) capsules for oral use [package insert]. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals Inc.; 2013. Available at: http://bidocs. boehringeringelheim.com/BIWebAccess/ViewServlet. ser?docBase=renetnt&folderPath=/Prescribing%20 Information/PIs/Pradaxa/Pradaxa.pdf. Accessed on 08/07/2015.
-
(2013)
PRADAXA (dabigatran Etexilate Mesylate) Capsules for Oral use [Package Insert]
-
-
-
57
-
-
77949421739
-
Influence of renal impairment on the pharmacokinetics and pharmacodynamics of oral dabigatran etexilate: An open-label, parallel-group, single-centre study
-
Stangier J, Rathgen K, Stähle H, Mazur D. Influence of renal impairment on the pharmacokinetics and pharmacodynamics of oral dabigatran etexilate: an open-label, parallel-group, single-centre study. Clin Pharmacokinet 2010;49:259-68.
-
(2010)
Clin Pharmacokinet
, vol.49
, pp. 259-268
-
-
Stangier, J.1
Rathgen, K.2
Stähle, H.3
Mazur, D.4
-
58
-
-
84941997771
-
-
Titusville, NJ: Janssen Pharmaceuticals, Inc, Accessed on 08/07/2015
-
Xarelto (rivaroxaban) prescribing information. Titusville, NJ: Janssen Pharmaceuticals, Inc. Available at: www.xareltohcp. com/sites/default/files/pdf/xarelto-0.pdf#zoom=100. Accessed on 08/07/2015.
-
Xarelto (rivaroxaban) Prescribing Information
-
-
-
59
-
-
84957808019
-
-
Princeton, NJ: Bristol-Myers Squibb Company, Accessed on 08/07/2015
-
Eliquis (apixaban) prescribing information. Princeton, NJ: Bristol-Myers Squibb Company. Available at: http://packageinserts.bms.com/pi/pi-eliquis.pdf. Accessed on 08/07/2015.
-
Eliquis (apixaban) Prescribing Information
-
-
-
60
-
-
79958844941
-
Adsorption of dabigatran etexilate in water or dabigatran in pooled human plasma by activated charcoal in vitro [Abstract]
-
van Ryn J, Sieger P, Kink-Eiband M, et al. Adsorption of dabigatran etexilate in water or dabigatran in pooled human plasma by activated charcoal in vitro [Abstract]. 51st ASH Annual Meeting and Exposition 2009; n. 1065.
-
(2009)
51st ASH Annual Meeting and Exposition
, pp. 1065
-
-
Van Ryn, J.1
Sieger, P.2
Kink-Eiband, M.3
-
61
-
-
84928969110
-
Novel oral anticoagulants: Efficacy, laboratory measurement, and approaches to emergent reversal
-
Gehrie E, Tormey C. Novel oral anticoagulants: efficacy, laboratory measurement, and approaches to emergent reversal. Arch Pathol Lab Med 2015;139:687-92.
-
(2015)
Arch Pathol Lab Med
, vol.139
, pp. 687-692
-
-
Gehrie, E.1
Tormey, C.2
-
62
-
-
84992062245
-
Prothrombin complex concentrates: And update
-
Franchini M, Lippi G. Prothrombin complex concentrates: and update. Blood Transfus 2010;40:812-24.
-
(2010)
Blood Transfus
, vol.40
, pp. 812-824
-
-
Franchini, M.1
Lippi, G.2
-
63
-
-
84893171895
-
Reversing the new oral anticoagulants with prothrombin complex concentrates (PCCs): What is the evidence
-
Dickneite G, Hoffman M. Reversing the new oral anticoagulants with prothrombin complex concentrates (PCCs): what is the evidence. Thromb Haemost 2014;11:189-98.
-
(2014)
Thromb Haemost
, vol.11
, pp. 189-198
-
-
Dickneite, G.1
Hoffman, M.2
-
64
-
-
84856214360
-
Hemostatic therapy in experimental intracerebral hemorrhage associated with the direct thrombin inhibitor dabigatran
-
Zhou W, Schwarting S, Illanes S, et al. Hemostatic therapy in experimental intracerebral hemorrhage associated with the direct thrombin inhibitor dabigatran. Stroke 2011;42:3594-9.
-
(2011)
Stroke
, vol.42
, pp. 3594-3599
-
-
Zhou, W.1
Schwarting, S.2
Illanes, S.3
-
65
-
-
84865773023
-
Reversal of dabigatran anticoagulation by prothrombin complex concentrate (Beriplex P/N) in a rabbit model
-
Pragst I, Zeitler SH, Doerr B, et al. Reversal of dabigatran anticoagulation by prothrombin complex concentrate (Beriplex P/N) in a rabbit model. J Thromb Haemost 2012;10:1841-8.
-
(2012)
J Thromb Haemost
, vol.10
, pp. 1841-1848
-
-
Pragst, I.1
Zeitler, S.H.2
Doerr, B.3
-
66
-
-
84858755308
-
The successful reversal of dabigatran-induced bleeding by coagulation factor concentrates in a rat tail bleeding model do not correlate with ex vivo markers of anticoagulation [Abstract]
-
van Ryn J, Kink-Eiband M, Clemens A. The successful reversal of dabigatran-induced bleeding by coagulation factor concentrates in a rat tail bleeding model do not correlate with ex vivo markers of anticoagulation [Abstract]. Blood 2011;118:2316.
-
(2011)
Blood
, vol.118
, pp. 2316
-
-
Van Ryn, J.1
Kink-Eiband, M.2
Clemens, A.3
-
67
-
-
84894258936
-
Non-clinical safety and efficacy of prothrombin complex concentrates (PCC) for the reversal of dabigatran mediated anticoagulation [Abstract]
-
Herzog E, Kaspereit F, Krege W, et al. Non-clinical safety and efficacy of prothrombin complex concentrates (PCC) for the reversal of dabigatran mediated anticoagulation [Abstract]. J Thromb Haemost 2013;11(Suppl 2):693.
-
(2013)
J Thromb Haemost
, vol.11
, pp. 693
-
-
Herzog, E.1
Kaspereit, F.2
Krege, W.3
-
68
-
-
84655176578
-
Evaluation of prothrombin complex concentrate and recombinant activated factor VII to reverse rivaroxaban in a rabbit model
-
Godier A, Miclot A, Le Bonniec B, et al. Evaluation of prothrombin complex concentrate and recombinant activated factor VII to reverse rivaroxaban in a rabbit model. Anesthesiology 2012;116:94-102.
-
(2012)
Anesthesiology
, vol.116
, pp. 94-102
-
-
Godier, A.1
Miclot, A.2
Le Bonniec, B.3
-
69
-
-
84883812030
-
In vitro assessment, using thrombin generation, of the applicability of prothrombin complex concentrate as an antidote for Rivaroxaban
-
Dinkelaar J, Molenaar PJ, Ninivaggi M, et al. In vitro assessment, using thrombin generation, of the applicability of prothrombin complex concentrate as an antidote for Rivaroxaban. J Thromb Haemost 2013;11:1111-8.
-
(2013)
J Thromb Haemost
, vol.11
, pp. 1111-1118
-
-
Dinkelaar, J.1
Molenaar, P.J.2
Ninivaggi, M.3
-
70
-
-
84922565475
-
Measurement and reversal of prophylactic and therapeutic peak levels of rivaroxaban: An in vitro study
-
Körber MK, Langer E, Ziemer S, et al. Measurement and reversal of prophylactic and therapeutic peak levels of rivaroxaban: an in vitro study. Clin Appl Thromb Hemost 2014;20:735-40.
-
(2014)
Clin Appl Thromb Hemost
, vol.20
, pp. 735-740
-
-
Körber, M.K.1
Langer, E.2
Ziemer, S.3
-
71
-
-
80053571188
-
Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: A randomized, placebo-controlled, crossover study in healthy subjects
-
Eerenberg ES, Kamphuisen PW, Sijpkens MK, et al. Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo-controlled, crossover study in healthy subjects. Circulation 2011;124:1573-9.
-
(2011)
Circulation
, vol.124
, pp. 1573-1579
-
-
Eerenberg, E.S.1
Kamphuisen, P.W.2
Sijpkens, M.K.3
-
72
-
-
84892921288
-
Reversal of apixaban induced alterations in hemostasis by different coagulation factor concentrates: Significance of studies in vitro with circulating human blood
-
Escolar G, Fernandez-Gallego V, Arellano-Rodrigo E, et al. Reversal of apixaban induced alterations in hemostasis by different coagulation factor concentrates: significance of studies in vitro with circulating human blood. PLoS One 2013;8:e78696.
-
(2013)
PLoS One
, vol.8
, pp. e78696
-
-
Escolar, G.1
Fernandez-Gallego, V.2
Arellano-Rodrigo, E.3
-
73
-
-
84908502375
-
Comparison of threefactor and four-factor prothrombin complex concentrates regarding reversal of the anticoagulant effects of rivaroxaban in healthy volunteers
-
Levi M, Moore KT, Castillejos CF, et al. Comparison of threefactor and four-factor prothrombin complex concentrates regarding reversal of the anticoagulant effects of rivaroxaban in healthy volunteers. J Thromb Haemost 2014;12:1428-36.
-
(2014)
J Thromb Haemost
, vol.12
, pp. 1428-1436
-
-
Levi, M.1
Moore, K.T.2
Castillejos, C.F.3
-
74
-
-
84943619924
-
The impact of prothrombin complex concentrate on the coagulopathy effects of edoxaban
-
Brown KS, Wickremasingha P, Parasrampuria DA, et al. The impact of prothrombin complex concentrate on the coagulopathy effects of edoxaban. JACC 2014;63:A2095.
-
(2014)
JACC
, vol.63
, pp. A2095
-
-
Brown, K.S.1
Wickremasingha, P.2
Parasrampuria, D.A.3
-
75
-
-
84897878284
-
Effects of rivaroxaban and dabigatran on hemostasis and reversion of their antithrombotic effects by different coagulation factors: Evidence raised from a clinical study in healthy volunteers [Abstract]
-
Galan AM, Arellano-Rodrigo E, Sanz V, et al. Effects of rivaroxaban and dabigatran on hemostasis and reversion of their antithrombotic effects by different coagulation factors: evidence raised from a clinical study in healthy volunteers [Abstract]. J Thromb Haemost 2013;11(Suppl 2):418.
-
(2013)
J Thromb Haemost
, vol.11
, pp. 418
-
-
Galan, A.M.1
Arellano-Rodrigo, E.2
Sanz, V.3
-
76
-
-
84897845470
-
Alterations induced by rivaroxaban on hemostasis can be reversed by different coagulation factor concentrates: In vitro experimental studies with steady and circulating human blood [Abstract]
-
Arellano-Rodrigo E, Galan AM, Sanz V, et al. Alterations induced by rivaroxaban on hemostasis can be reversed by different coagulation factor concentrates: in vitro experimental studies with steady and circulating human blood [Abstract]. J Thromb Haemost 2013;11(Suppl 2):953.
-
(2013)
J Thromb Haemost
, vol.11
, pp. 953
-
-
Arellano-Rodrigo, E.1
Galan, A.M.2
Sanz, V.3
-
77
-
-
84879671176
-
Reversal of rivaroxaban anticoagulation by haemostatic agents in rats and primates
-
Perzborn E, Gruber A, Tinel H, et al. Reversal of rivaroxaban anticoagulation by haemostatic agents in rats and primates. Thromb Haemost 2013;110:162-72.
-
(2013)
Thromb Haemost
, vol.110
, pp. 162-172
-
-
Perzborn, E.1
Gruber, A.2
Tinel, H.3
-
78
-
-
84859951446
-
Reversal of dabigatran using recombinant activated factor VII and activated prothrombin complex concentrates in thromboelastography assay
-
Chan HHW, Atkinson HM, Goncharenko M, et al. Reversal of dabigatran using recombinant activated factor VII and activated prothrombin complex concentrates in thromboelastography assay. J Thromb Haemost 2011;9:576-7.
-
(2011)
J Thromb Haemost
, vol.9
, pp. 576-577
-
-
Chan, H.H.W.1
Atkinson, H.M.2
Goncharenko, M.3
-
79
-
-
84864370719
-
Effect of non-specific reversal agents on anticoagulant activity of dabigatran and rivaroxaban: A randomised crossover ex vivo study in healthy volunteers
-
Marlu R, Hodaj E, Paris A, et al. Effect of non-specific reversal agents on anticoagulant activity of dabigatran and rivaroxaban: a randomised crossover ex vivo study in healthy volunteers. Thromb Haemost 2012;108:217-24.
-
(2012)
Thromb Haemost
, vol.108
, pp. 217-224
-
-
Marlu, R.1
Hodaj, E.2
Paris, A.3
-
80
-
-
84875053456
-
The use of FEIBA in the correction of coagulation abnormalities induce by dabigatran
-
Khoo TL W C, Kershaw G, Reddel CJ, et al. The use of FEIBA in the correction of coagulation abnormalities induce by dabigatran. Int J Lab Hem 2013;35:222-4.
-
(2013)
Int J Lab Hem
, vol.35
, pp. 222-224
-
-
Khoo, T.L.W.C.1
Kershaw, G.2
Reddel, C.J.3
-
81
-
-
84899721137
-
Thrombin generation using the calibrated automated thrombinoscope to assess reversibility of dabigatran and rivaroxaban
-
Herrmann R, Thom J, Wood A, et al. Thrombin generation using the calibrated automated thrombinoscope to assess reversibility of dabigatran and rivaroxaban. Thromb Haemost 2014;111:989-95.
-
(2014)
Thromb Haemost
, vol.111
, pp. 989-995
-
-
Herrmann, R.1
Thom, J.2
Wood, A.3
-
82
-
-
84923769426
-
Multimodal assessment of non-specific hemostatic agents for apixaban reversal
-
Martin AC, Gouin-Thibault I, Siguret V, et al. Multimodal assessment of non-specific hemostatic agents for apixaban reversal. J Thromb Haemost 2015;13:426-36.
-
(2015)
J Thromb Haemost
, vol.13
, pp. 426-436
-
-
Martin, A.C.1
Gouin-Thibault, I.2
Siguret, V.3
-
83
-
-
84865793090
-
Prothrombin complex concentrates reduce blood loss in murine coagulopathy induced by warfarin, but not in that induced by dabigatran etexilate
-
Lambourne MD, Eltringham-Smith LJ, Gataiance S, et al. Prothrombin complex concentrates reduce blood loss in murine coagulopathy induced by warfarin, but not in that induced by dabigatran etexilate. J Thromb Haemost 2012;10:1830-40.
-
(2012)
J Thromb Haemost
, vol.10
, pp. 1830-1840
-
-
Lambourne, M.D.1
Eltringham-Smith, L.J.2
Gataiance, S.3
-
84
-
-
84856631805
-
Reversal of anticoagulant effects of edoxaban, an oral, direct factor Xa inhibitor, with haemostatic agents
-
Fukuda T, Honda Y, Kamisato C, et al. Reversal of anticoagulant effects of edoxaban, an oral, direct factor Xa inhibitor, with haemostatic agents. Thromb Haemost 2012;107:253-9.
-
(2012)
Thromb Haemost
, vol.107
, pp. 253-259
-
-
Fukuda, T.1
Honda, Y.2
Kamisato, C.3
-
85
-
-
84898784649
-
Reversal of new, factor-specific oral anticoagulants by rFVIIa, prothrombin complex concentrate and activated protrhombin complex concentrate: A review of animal and human studies
-
Lee FMH, Chan AKC, Lau KK, Chan HH. Reversal of new, factor-specific oral anticoagulants by rFVIIa, prothrombin complex concentrate and activated protrhombin complex concentrate: a review of animal and human studies. Thromb Res 2014;133:705-13.
-
(2014)
Thromb Res
, vol.133
, pp. 705-713
-
-
Lee, F.M.H.1
Chan, A.K.C.2
Lau, K.K.3
Chan, H.H.4
-
86
-
-
84879548455
-
A specific antidote for dabigatran: Functional and structural characterization
-
Schiele F, van Ryn J, Canada K, et al. A specific antidote for dabigatran: functional and structural characterization. Blood 2013;121:3554-62.
-
(2013)
Blood
, vol.121
, pp. 3554-3562
-
-
Schiele, F.1
Van Ryn, J.2
Canada, K.3
-
87
-
-
84896397052
-
A specific antidote for dabigatran: Immediate, complete and sustained reversal of dabigatran induced anticoagulation in healthy male volunteers [Abstract]
-
Glund S, Stangier J, Schmohl M, et al. A specific antidote for dabigatran: immediate, complete and sustained reversal of dabigatran induced anticoagulation in healthy male volunteers [Abstract]. Circulation 2013;128:A17765.
-
(2013)
Circulation
, vol.128
, pp. A17765
-
-
Glund, S.1
Stangier, J.2
Schmohl, M.3
-
88
-
-
84939469874
-
Safety, tolerability, and efficacy of idarucizumab for the reversal of the anticoagulant effect of dabigatran in healthy male volunteers: A randomised, placebo-controlled, double-blind phase 1 trial
-
Glund S, Stangier J, Schmohl M, et al. Safety, tolerability, and efficacy of idarucizumab for the reversal of the anticoagulant effect of dabigatran in healthy male volunteers: a randomised, placebo-controlled, double-blind phase 1 trial. Lancet 2015;386:680-90.
-
(2015)
Lancet
, vol.386
, pp. 680-690
-
-
Glund, S.1
Stangier, J.2
Schmohl, M.3
-
90
-
-
84925503252
-
Idarucizumab, a specific antidote for dabigatran: Immediate, complete and sustained reversal of dabigatran induced anticoagulation in elderly and renally impaired subjects [abstract]
-
Glund S, Stangier J, Schmohl M, et al. Idarucizumab, a specific antidote for dabigatran: immediate, complete and sustained reversal of dabigatran induced anticoagulation in elderly and renally impaired subjects [abstract]. Blood 2014;124:344.
-
(2014)
Blood
, vol.124
, pp. 344
-
-
Glund, S.1
Stangier, J.2
Schmohl, M.3
-
91
-
-
84930965307
-
A randomised study in healthy volunteers to investigate the safety, tolerability and pharmacokinetics of idarucizumab, a specific antidote to dabigatran
-
Glund S, Moschetti V, Norris S, et al. A randomised study in healthy volunteers to investigate the safety, tolerability and pharmacokinetics of idarucizumab, a specific antidote to dabigatran. Thromb Haemost 2015;113:943-51.
-
(2015)
Thromb Haemost
, vol.113
, pp. 943-951
-
-
Glund, S.1
Moschetti, V.2
Norris, S.3
-
92
-
-
84931291673
-
Reversal of anticoagulants: An overview of current developments
-
Greinacher A, Thiele T, Selleng K. Reversal of anticoagulants: an overview of current developments. Thromb Haemost 2015;113:931-42.
-
(2015)
Thromb Haemost
, vol.113
, pp. 931-942
-
-
Greinacher, A.1
Thiele, T.2
Selleng, K.3
-
93
-
-
84904318453
-
γT-S195A thrombin reduces the anticoagulant effects of dabigatran in vitro and in vivo
-
Sheffield WP, Lambourne MD, Eltringham-Smith LJ, et al. γT-S195A thrombin reduces the anticoagulant effects of dabigatran in vitro and in vivo. J Thromb Haemost 2014;12:1110-5.
-
(2014)
J Thromb Haemost
, vol.12
, pp. 1110-1115
-
-
Sheffield, W.P.1
Lambourne, M.D.2
Eltringham-Smith, L.J.3
-
94
-
-
84878460192
-
A specific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor Xa
-
Lu G, DeGuzman FR, Hollenbach SJ, et al. A specific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor Xa. Nat Med 2013;19:446-51.
-
(2013)
Nat Med
, vol.19
, pp. 446-451
-
-
Lu, G.1
DeGuzman, F.R.2
Hollenbach, S.J.3
-
95
-
-
84897905764
-
Randomized, double-blind, placebo-controlled single ascending dose pharmacokinetic and pharmacodynamic study of PRT064445, a universal antidote for factor Xa inhibitors [Abstract]
-
Crowther MA, Kitt M, McClure M, et al. Randomized, double-blind, placebo-controlled single ascending dose pharmacokinetic and pharmacodynamic study of PRT064445, a universal antidote for factor Xa inhibitors [Abstract]. Arterioscler Thromb Vasc Biol 2013;33:A10.
-
(2013)
Arterioscler Thromb Vasc Biol
, vol.33
, pp. A10
-
-
Crowther, M.A.1
Kitt, M.2
McClure, M.3
-
96
-
-
84885203373
-
A phase 2 randomized, double-blind, placebo-controlled trial of PRT064445, a novel, universal antidote for direct and indirect factor Xa inhibitors [Abstract]
-
Crowther MA, Kitt M, Lorenz T, et al. A phase 2 randomized, double-blind, placebo-controlled trial of PRT064445, a novel, universal antidote for direct and indirect factor Xa inhibitors [Abstract]. J Thromb Haemost 2013;11(Suppl):AS20.1.
-
(2013)
J Thromb Haemost
, vol.11
, pp. AS201
-
-
Crowther, M.A.1
Kitt, M.2
Lorenz, T.3
-
97
-
-
84896638883
-
A phase 2 randomized, double-blind, placebo-controlled trial demonstrating reversal of rivaroxaban induced anticoagulation in healthy subjects by andexanet alfa (PRT064445), an antidote for FXa inhibitors [Abstract]
-
Crowther MA, Mathur V, Kitt M, et al. A phase 2 randomized, double-blind, placebo-controlled trial demonstrating reversal of rivaroxaban induced anticoagulation in healthy subjects by andexanet alfa (PRT064445), an antidote for FXa inhibitors [Abstract]. Blood 2013;122:A3636.
-
(2013)
Blood
, vol.122
, pp. A3636
-
-
Crowther, M.A.1
Mathur, V.2
Kitt, M.3
-
98
-
-
84922938167
-
™-A: A phase 3 randomized, double-blind, placebo-controlled trial, demonstrating reversal of apixaban-induced anticoagulation in older subjects by andexanet alfa (PRT064445), a universal antidote for factor Xa (FXa) inhibitors [Abstract]
-
™-A: A phase 3 randomized, double-blind, placebo-controlled trial, demonstrating reversal of apixaban-induced anticoagulation in older subjects by andexanet alfa (PRT064445), a universal antidote for factor Xa (FXa) inhibitors [Abstract]. Circulation 2014;130:2116.
-
(2014)
Circulation
, vol.130
, pp. 2116
-
-
Crowther, M.1
Levy, G.G.2
Lu, G.3
-
99
-
-
84979578521
-
™-A PART 2: A phase 3 randomized, double-blind, placebo-controlled trial, demonstrating sustained reversal of apixabaninduced anticoagulation in older subjects by andexanet alfa (PRT064445), a universal antidote for factor Xa (FXa) inhibitors [Abstract]
-
™-A PART 2: A phase 3 randomized, double-blind, placebo-controlled trial, demonstrating sustained reversal of apixabaninduced anticoagulation in older subjects by andexanet alfa (PRT064445), a universal antidote for factor Xa (FXa) inhibitors [Abstract]. J Thromb Haemost 2015;13(Suppl 2):84.
-
(2015)
J Thromb Haemost
, vol.13
, pp. 84
-
-
Crowther, M.1
Gold, A.2
Lu, G.3
-
100
-
-
84992015536
-
-
ClinicalTrials. gov. NCT02329327, Accessed on 08/07/2015
-
Recombinant Factor Xa Inhibitor Antidote. ClinicalTrials. gov. NCT02329327. Available at: https://clinicaltrials.gov/ct2/show/NCT02329327. Accessed on 08/07/2015.
-
Recombinant Factor Xa Inhibitor Antidote
-
-
-
101
-
-
84878342946
-
Small molecule antidote for anticoagulants [Abstract]
-
Laulicht B, Bakhru S, Lee C, et al. Small molecule antidote for anticoagulants [Abstract]. Circulation 2012;126:10021.
-
(2012)
Circulation
, vol.126
, pp. 10021
-
-
Laulicht, B.1
Bakhru, S.2
Lee, C.3
-
104
-
-
84915821873
-
Use of PER977 to reverse the anticoagulant effect of edoxaban [Letter]
-
Ansell JE, Bakhru SH, Laulicht BE, et al. Use of PER977 to reverse the anticoagulant effect of edoxaban [Letter]. N Engl J Med 2014;371:2141-2.
-
(2014)
N Engl J Med
, vol.371
, pp. 2141-2142
-
-
Ansell, J.E.1
Bakhru, S.H.2
Laulicht, B.E.3
|