메뉴 건너뛰기




Volumn 58, Issue 6, 2014, Pages 651-659

New oral anticoagulants: Clinical indications, monitoring and treatment of acute bleeding complications

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED CARBON; ANTICOAGULANT AGENT; APIXABAN; DABIGATRAN; DABIGATRAN ETEXILATE; FRESH FROZEN PLASMA; HEMOSTATIC AGENT; RIVAROXABAN; BENZIMIDAZOLE DERIVATIVE; BETA ALANINE; BLOOD CLOTTING FACTOR 10A INHIBITOR; MORPHOLINE DERIVATIVE; PYRAZOLE DERIVATIVE; PYRIDONE DERIVATIVE; THIOPHENE DERIVATIVE; THROMBIN;

EID: 84903135364     PISSN: 00015172     EISSN: 13996576     Source Type: Journal    
DOI: 10.1111/aas.12319     Document Type: Review
Times cited : (25)

References (44)
  • 1
    • 84870363348 scopus 로고    scopus 로고
    • The discovery of vitamin K and its clinical applications
    • Ferland G,. The discovery of vitamin K and its clinical applications. Ann Nutr Metab 2012; 61: 213-218.
    • (2012) Ann Nutr Metab , vol.61 , pp. 213-218
    • Ferland, G.1
  • 2
    • 84869095094 scopus 로고    scopus 로고
    • New anticoagulants for treatment of venous thromboembolism
    • Franchini M, Mannucci PM,. New anticoagulants for treatment of venous thromboembolism. Eur J Intern Med 2012; 23: 692-695.
    • (2012) Eur J Intern Med , vol.23 , pp. 692-695
    • Franchini, M.1    Mannucci, P.M.2
  • 7
    • 84882909945 scopus 로고    scopus 로고
    • Novel oral anticoagulants: Clinical pharmacology, indications and practical considerations
    • Harder S, Graff J,. Novel oral anticoagulants: clinical pharmacology, indications and practical considerations. Eur J Clin Pharmacol 2013; 69: 1617-1633.
    • (2013) Eur J Clin Pharmacol , vol.69 , pp. 1617-1633
    • Harder, S.1    Graff, J.2
  • 8
    • 79957706195 scopus 로고    scopus 로고
    • New oral antithrombotic agents for the prevention of deep venous thrombosis and pulmonary embolism in orthopedic surgery
    • Merli GJ,. New oral antithrombotic agents for the prevention of deep venous thrombosis and pulmonary embolism in orthopedic surgery. Orthopedics 2010; 33: 27-32.
    • (2010) Orthopedics , vol.33 , pp. 27-32
    • Merli, G.J.1
  • 10
    • 84865642185 scopus 로고    scopus 로고
    • New oral anticoagulants: A review of the literature with particular emphasis on patients with impaired renal function
    • Poulsen BK, Grove EL, Husted SE,. New oral anticoagulants: a review of the literature with particular emphasis on patients with impaired renal function. Drugs 2012; 72: 1739-1753.
    • (2012) Drugs , vol.72 , pp. 1739-1753
    • Poulsen, B.K.1    Grove, E.L.2    Husted, S.E.3
  • 11
    • 84865045736 scopus 로고    scopus 로고
    • Fatal gastrointestinal hemorrhage after a single dose of dabigatran
    • Kernan L, Ito S, Shirazi F, Boesen K,. Fatal gastrointestinal hemorrhage after a single dose of dabigatran. Clin Toxicol (Phila) 2012; 50: 571-573.
    • (2012) Clin Toxicol (Phila) , vol.50 , pp. 571-573
    • Kernan, L.1    Ito, S.2    Shirazi, F.3    Boesen, K.4
  • 12
    • 84862243930 scopus 로고    scopus 로고
    • Rectal bleeding and hemostatic disorders induced by dabigatran etexilate in 2 elderly patients
    • Béné J, Saïd W, Rannou M, Deheul S, Coupe P, Gautier S,. Rectal bleeding and hemostatic disorders induced by dabigatran etexilate in 2 elderly patients. Ann Pharmacother 2012; 46: e14.
    • (2012) Ann Pharmacother , vol.46
    • Béné, J.1    Saïd, W.2    Rannou, M.3    Deheul, S.4    Coupe, P.5    Gautier, S.6
  • 13
    • 84859703006 scopus 로고    scopus 로고
    • Dabigatran-induced gastrointestinal bleeding in an elderly patient with moderate renal impairment
    • Wychowski MK, Kouides PA,. Dabigatran-induced gastrointestinal bleeding in an elderly patient with moderate renal impairment. Ann Pharmacother 2012; 46: e10.
    • (2012) Ann Pharmacother , vol.46
    • Wychowski, M.K.1    Kouides, P.A.2
  • 14
    • 84859549864 scopus 로고    scopus 로고
    • Clinical challenges in a patient with dabigatran-induced fatal hemorrhage
    • Cano EL, Miyares MA,. Clinical challenges in a patient with dabigatran-induced fatal hemorrhage. Am J Geriatr Pharmacother 2012; 10: 160-163.
    • (2012) Am J Geriatr Pharmacother , vol.10 , pp. 160-163
    • Cano, E.L.1    Miyares, M.A.2
  • 15
    • 77953168824 scopus 로고    scopus 로고
    • Dabigatran etexilate - A novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity
    • van Ryn J, Stangier J, Haertter S, Liesenfeld KH, Wienen W, Feuring M, Clemens A,. Dabigatran etexilate-a novel, reversible, oral direct thrombin inhibitor: interpretation of coagulation assays and reversal of anticoagulant activity. Thromb Haemost 2010; 103: 1116-1127.
    • (2010) Thromb Haemost , vol.103 , pp. 1116-1127
    • Van Ryn, J.1    Stangier, J.2    Haertter, S.3    Liesenfeld, K.H.4    Wienen, W.5    Feuring, M.6    Clemens, A.7
  • 17
    • 84872260247 scopus 로고    scopus 로고
    • Apixaban, an oral, direct factor Xa inhibitor: Single dose safety, pharmacokinetics, pharmacodynamics and food effect in healthy subjects
    • Frost C, Wang J, Nepal S, Schuster A, Barrett YC, Mosqueda-Garcia R, Reeves RA, LaCreta F,. Apixaban, an oral, direct factor Xa inhibitor: single dose safety, pharmacokinetics, pharmacodynamics and food effect in healthy subjects. Br J Clin Pharmacol 2013; 75: 476-487.
    • (2013) Br J Clin Pharmacol , vol.75 , pp. 476-487
    • Frost, C.1    Wang, J.2    Nepal, S.3    Schuster, A.4    Barrett, Y.C.5    Mosqueda-Garcia, R.6    Reeves, R.A.7    Lacreta, F.8
  • 18
    • 77955926663 scopus 로고    scopus 로고
    • Quantification of apixaban's therapeutic utility in prevention of venous thromboembolism: Selection of phase III trial dose
    • Leil TA, Feng Y, Zhang L, Paccaly A, Mohan P, Pfister M,. Quantification of apixaban's therapeutic utility in prevention of venous thromboembolism: selection of phase III trial dose. Clin Pharmacol Ther 2010; 88: 375-382.
    • (2010) Clin Pharmacol Ther , vol.88 , pp. 375-382
    • Leil, T.A.1    Feng, Y.2    Zhang, L.3    Paccaly, A.4    Mohan, P.5    Pfister, M.6
  • 19
    • 84856632988 scopus 로고    scopus 로고
    • Evaluation of the anti-factor Xa chromogenic assay for the measurement of rivaroxaban plasma concentrations using calibrators and controls
    • Rivaroxaban Anti-Factor Xa Chromogenic Assay Field Trial Laboratories
    • Samama MM, Contant G, Spiro TE, Perzborn E, Guinet C, Gourmelin Y, Le Flem L, Rohde G, Martinoli JL, Rivaroxaban Anti-Factor Xa Chromogenic Assay Field Trial Laboratories. Evaluation of the anti-factor Xa chromogenic assay for the measurement of rivaroxaban plasma concentrations using calibrators and controls. Thromb Haemost 2012; 107: 379-387.
    • (2012) Thromb Haemost , vol.107 , pp. 379-387
    • Samama, M.M.1    Contant, G.2    Spiro, T.E.3    Perzborn, E.4    Guinet, C.5    Gourmelin, Y.6    Le Flem, L.7    Rohde, G.8    Martinoli, J.L.9
  • 21
    • 78649736882 scopus 로고    scopus 로고
    • Clinical laboratory measurement of direct factor Xa inhibitors: Anti-Xa assay is preferable to prothrombin time assay
    • Barrett YC, Wang Z, Frost C, Shenker A,. Clinical laboratory measurement of direct factor Xa inhibitors: anti-Xa assay is preferable to prothrombin time assay. Thromb Haemost 2010; 104: 1263-1271.
    • (2010) Thromb Haemost , vol.104 , pp. 1263-1271
    • Barrett, Y.C.1    Wang, Z.2    Frost, C.3    Shenker, A.4
  • 22
    • 84880571372 scopus 로고    scopus 로고
    • Management of major bleeding complications and emergency surgery in patients on long-term treatment with direct oral anticoagulants, thrombin or factor-Xa inhibitors: Proposals of the working group on perioperative haemostasis (GIHP) - March 2013
    • Working Group on Perioperative Haemostasis
    • Pernod G, Albaladejo P, Godier A, Samama CM, Susen S, Gruel Y, Blais N, Fontana P, Cohen A, Llau JV, Rosencher N, Schved JF, de Maistre E, Samama MM, Mismetti P, Sié P, Working Group on Perioperative Haemostasis. Management of major bleeding complications and emergency surgery in patients on long-term treatment with direct oral anticoagulants, thrombin or factor-Xa inhibitors: proposals of the working group on perioperative haemostasis (GIHP)-March 2013. Arch Cardiovasc Dis 2013; 106: 382-393.
    • (2013) Arch Cardiovasc Dis , vol.106 , pp. 382-393
    • Pernod, G.1    Albaladejo, P.2    Godier, A.3    Samama, C.M.4    Susen, S.5    Gruel, Y.6    Blais, N.7    Fontana, P.8    Cohen, A.9    Llau, J.V.10    Rosencher, N.11    Schved, J.F.12    De Maistre, E.13    Samama, M.M.14    Mismetti, P.15    Sié, P.16
  • 23
    • 84869189977 scopus 로고    scopus 로고
    • Periprocedural management and approach to bleeding in patients taking dabigatran
    • Weitz JI, Quinlan DJ, Eikelboom JW,. Periprocedural management and approach to bleeding in patients taking dabigatran. Circulation 2012; 126: 2428-2432.
    • (2012) Circulation , vol.126 , pp. 2428-2432
    • Weitz, J.I.1    Quinlan, D.J.2    Eikelboom, J.W.3
  • 26
  • 30
    • 80053571188 scopus 로고    scopus 로고
    • Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: A randomized, placebo-controlled, crossover study in healthy subjects
    • Eerenberg ES, Kamphuisen PW, Sijpkens MK, Meijers JC, Buller HR, Levi M,. Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo-controlled, crossover study in healthy subjects. Circulation 2011; 124: 1573-1579.
    • (2011) Circulation , vol.124 , pp. 1573-1579
    • Eerenberg, E.S.1    Kamphuisen, P.W.2    Sijpkens, M.K.3    Meijers, J.C.4    Buller, H.R.5    Levi, M.6
  • 31
    • 84864370719 scopus 로고    scopus 로고
    • Effect of non-specific reversal agents on anticoagulant activity of dabigatran and rivaroxaban: A randomised crossover ex vivo study in healthy volunteers
    • Marlu R, Hodaj E, Paris A, Albaladejo P, Cracowski JL, Pernod G,. Effect of non-specific reversal agents on anticoagulant activity of dabigatran and rivaroxaban: a randomised crossover ex vivo study in healthy volunteers. Thromb Haemost 2012; 108: 217-224.
    • (2012) Thromb Haemost , vol.108 , pp. 217-224
    • Marlu, R.1    Hodaj, E.2    Paris, A.3    Albaladejo, P.4    Cracowski, J.L.5    Pernod, G.6
  • 32
    • 84867240886 scopus 로고    scopus 로고
    • New direct oral anticoagulants - Current therapeutic options and treatment recommendations for bleeding complications
    • Miesbach W, Seifried E,. New direct oral anticoagulants-current therapeutic options and treatment recommendations for bleeding complications. Thromb Haemost 2012; 108: 625-632.
    • (2012) Thromb Haemost , vol.108 , pp. 625-632
    • Miesbach, W.1    Seifried, E.2
  • 34
    • 84858418494 scopus 로고    scopus 로고
    • Recombinant activated factor VII and prothrombin complex concentrates have different effects on bleeding and arterial thrombosis in the haemodiluted rabbit
    • Le Saché F, Le Bonniec B, Gaussem P, Dizier B, Tagzirt M, Godier A, Emmerich J, Samama CM,. Recombinant activated factor VII and prothrombin complex concentrates have different effects on bleeding and arterial thrombosis in the haemodiluted rabbit. Br J Anaesth 2012; 108: 586-593.
    • (2012) Br J Anaesth , vol.108 , pp. 586-593
    • Le Saché, F.1    Le Bonniec, B.2    Gaussem, P.3    Dizier, B.4    Tagzirt, M.5    Godier, A.6    Emmerich, J.7    Samama, C.M.8
  • 36
    • 78049498149 scopus 로고    scopus 로고
    • Safety of recombinant activated factor VII in randomized clinical trials
    • Levi M, Levy JH, Andersen HF, Truloff D,. Safety of recombinant activated factor VII in randomized clinical trials. N Engl J Med 2010; 363: 1791-1800.
    • (2010) N Engl J Med , vol.363 , pp. 1791-1800
    • Levi, M.1    Levy, J.H.2    Andersen, H.F.3    Truloff, D.4
  • 38
    • 84877301336 scopus 로고    scopus 로고
    • European Heart Rhythm Association Practical Guide on the use of new oral anticoagulants in patients with non-valvular atrial fibrillation
    • European Heart Rhythm Association
    • Heidbuchel H, Verhamme P, Alings M, Antz M, Hacke W, Oldgren J, Sinnaeve P, Camm AJ, Kirchhof P, European Heart Rhythm Association. European Heart Rhythm Association Practical Guide on the use of new oral anticoagulants in patients with non-valvular atrial fibrillation. Europace 2013; 15: 625-651.
    • (2013) Europace , vol.15 , pp. 625-651
    • Heidbuchel, H.1    Verhamme, P.2    Alings, M.3    Antz, M.4    Hacke, W.5    Oldgren, J.6    Sinnaeve, P.7    Camm, A.J.8    Kirchhof, P.9
  • 40
    • 84880737167 scopus 로고    scopus 로고
    • Practical management of bleeding due to the anticoagulants dabigatran, rivaroxaban, and apixaban
    • Fawole A, Daw HA, Crowther MA,. Practical management of bleeding due to the anticoagulants dabigatran, rivaroxaban, and apixaban. Cleve Clin J Med 2013; 80: 443-451.
    • (2013) Cleve Clin J Med , vol.80 , pp. 443-451
    • Fawole, A.1    Daw, H.A.2    Crowther, M.A.3
  • 41
    • 77949421739 scopus 로고    scopus 로고
    • Influence of renal impairment on the pharmacokinetics and pharmacodynamics of oral dabigatran etexilate: An open-label, parallel-group, single-centre study
    • Stangier J, Rathgen K, Stähle H, Mazur D,. Influence of renal impairment on the pharmacokinetics and pharmacodynamics of oral dabigatran etexilate: an open-label, parallel-group, single-centre study. Clin Pharmacokinet 2010; 49: 259-268.
    • (2010) Clin Pharmacokinet , vol.49 , pp. 259-268
    • Stangier, J.1    Rathgen, K.2    Stähle, H.3    Mazur, D.4
  • 42
    • 84857759555 scopus 로고    scopus 로고
    • Recombinant factor VIIa (rFVIIa) and hemodialysis to manage massive dabigatran-associated postcardiac surgery bleeding
    • Warkentin TE, Margetts P, Connolly SJ, Lamy A, Ricci C, Eikelboom JW,. Recombinant factor VIIa (rFVIIa) and hemodialysis to manage massive dabigatran-associated postcardiac surgery bleeding. Blood 2012; 119: 2172-2174.
    • (2012) Blood , vol.119 , pp. 2172-2174
    • Warkentin, T.E.1    Margetts, P.2    Connolly, S.J.3    Lamy, A.4    Ricci, C.5    Eikelboom, J.W.6
  • 43
    • 78349242482 scopus 로고    scopus 로고
    • Regional anaesthesia and antithrombotic agents: Recommendations of the European Society of Anaesthesiology
    • European Society of Anaesthesiology
    • Gogarten W, Vandermeulen E, Van Aken H, Kozek S, Llau JV, Samama CM, European Society of Anaesthesiology. Regional anaesthesia and antithrombotic agents: recommendations of the European Society of Anaesthesiology. Eur J Anaesthesiol 2010; 27: 999-1015.
    • (2010) Eur J Anaesthesiol , vol.27 , pp. 999-1015
    • Gogarten, W.1    Vandermeulen, E.2    Van Aken, H.3    Kozek, S.4    Llau, J.V.5    Samama, C.M.6
  • 44
    • 84873531119 scopus 로고    scopus 로고
    • Do ingredients make the difference?: Finding the best cocktail of an anticoagulant with antiplatelets
    • Sinnaeve PR, Van de Werf F,. Do ingredients make the difference?: finding the best cocktail of an anticoagulant with antiplatelets. Circulation 2013; 127: 566-568.
    • (2013) Circulation , vol.127 , pp. 566-568
    • Sinnaeve, P.R.1    Van De Werf, F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.