Prothrombin complex concentrates reduce blood loss in murine coagulopathy induced by warfarin, but not in that induced by dabigatran etexilate

Journal of Thrombosis and Haemostasis

Volumn 10, Issue 9, 2012, Pages 1830-1840

  Lambourne, M D ^a   Eltringham Smith, L J ^a   Gataiance, S ^a   Arnold, D M ^a   Crowther, M A ^a   Sheffield, W P ^a  

^a MCMASTER UNIVERSITY   (Canada)

Author keywords

Bleeding; Dabigatran etexilate; Fresh frozen plasma (FFP); Prothrombin complex concentrates (PCCs); Warfarin

Indexed keywords

ACTIVATED PROTHROMBIN COMPLEX; DABIGATRAN ETEXILATE; FRESH FROZEN PLASMA; PROTHROMBIN; PROTHROMBIN COMPLEX; RECOMBINANT BLOOD CLOTTING FACTOR 7A; WARFARIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING; BLEEDING TIME; BLOOD CLOTTING; BLOOD VOLUME; CONTROLLED STUDY; DRUG EFFECT; IN VITRO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTHROMBIN TIME; TREATMENT OUTCOME;

ANIMALS; ANTICOAGULANTS; ANTITHROMBIN PROTEINS; BENZIMIDAZOLES; BLOOD COAGULATION DISORDERS; MICE; PROTHROMBIN; PYRIDINES; WARFARIN;

EID: 84865793090     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2012.04863.x     Document Type: Article

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