-
1
-
-
84856772158
-
Evidence-based management of anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
-
Holbrook A., Schulman S., Witt D.M., et al. Evidence-based management of anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012, 141:e152S-e184S.
-
(2012)
Chest
, vol.141
-
-
Holbrook, A.1
Schulman, S.2
Witt, D.M.3
-
2
-
-
34547433185
-
Death and disability from warfarin-associated intracranial and extracranial hemorrhages
-
Fang M.C., Go A.S., Chang Y., et al. Death and disability from warfarin-associated intracranial and extracranial hemorrhages. Am J Med 2007, 120:700-705.
-
(2007)
Am J Med
, vol.120
, pp. 700-705
-
-
Fang, M.C.1
Go, A.S.2
Chang, Y.3
-
3
-
-
70349306707
-
Dabigatran versus warfarin in patients with atrial fibrillation
-
Connolly S.J., Ezekowitz M.D., Yusuf S., et al. Dabigatran versus warfarin in patients with atrial fibrillation. NEngl J Med 2009, 361:1139-1151.
-
(2009)
NEngl J Med
, vol.361
, pp. 1139-1151
-
-
Connolly, S.J.1
Ezekowitz, M.D.2
Yusuf, S.3
-
4
-
-
80052825103
-
Apixaban versus warfarin in patients with atrial fibrillation
-
Granger C.B., Alexander J.H., McMurray J.J., et al. Apixaban versus warfarin in patients with atrial fibrillation. NEngl J Med 2011, 365:981-992.
-
(2011)
NEngl J Med
, vol.365
, pp. 981-992
-
-
Granger, C.B.1
Alexander, J.H.2
McMurray, J.J.3
-
5
-
-
80052592404
-
Rivaroxaban versus warfarin in nonvalvular atrial fibrillation
-
Patel M.R., Mahaffey K.W., Garg J., et al. Rivaroxaban versus warfarin in nonvalvular atrial fibrillation. NEngl J Med 2011, 365:883-891.
-
(2011)
NEngl J Med
, vol.365
, pp. 883-891
-
-
Patel, M.R.1
Mahaffey, K.W.2
Garg, J.3
-
6
-
-
84863301351
-
Poor prognosis in warfarin-associated intracranial hemorrhage despite anticoagulation reversal
-
Dowlatshahi D., Butcher K.S., Asdaghi N., et al. Poor prognosis in warfarin-associated intracranial hemorrhage despite anticoagulation reversal. Stroke 2012, 43:1812-1817.
-
(2012)
Stroke
, vol.43
, pp. 1812-1817
-
-
Dowlatshahi, D.1
Butcher, K.S.2
Asdaghi, N.3
-
7
-
-
84858595913
-
Focused 2012 update of the Canadian Cardiovascular Society atrial fibrillation guidelines: recommendations for stroke prevention and rate/rhythm control
-
Skanes A.C., Healey J.S., Cairns J.A., et al. Focused 2012 update of the Canadian Cardiovascular Society atrial fibrillation guidelines: recommendations for stroke prevention and rate/rhythm control. Can J Cardiol 2012, 28:125-136.
-
(2012)
Can J Cardiol
, vol.28
, pp. 125-136
-
-
Skanes, A.C.1
Healey, J.S.2
Cairns, J.A.3
-
8
-
-
79952301326
-
Apixaban in patients with atrial fibrillation
-
Connolly S.J., Eikelboom J., Joyner C., et al. Apixaban in patients with atrial fibrillation. NEngl J Med 2011, 364:806-817.
-
(2011)
NEngl J Med
, vol.364
, pp. 806-817
-
-
Connolly, S.J.1
Eikelboom, J.2
Joyner, C.3
-
9
-
-
84862907587
-
Rivaroxaban in patients with a recent acute coronary syndrome
-
Mega J.L., Braunwald E., Wiviott S.D., et al. Rivaroxaban in patients with a recent acute coronary syndrome. NEngl J Med 2012, 366:9-19.
-
(2012)
NEngl J Med
, vol.366
, pp. 9-19
-
-
Mega, J.L.1
Braunwald, E.2
Wiviott, S.D.3
-
10
-
-
80052162121
-
Apixaban with antiplatelet therapy after acute coronary syndrome
-
Alexander J.H., Lopes R.D., James S., et al. Apixaban with antiplatelet therapy after acute coronary syndrome. NEngl J Med 2011, 365:699-708.
-
(2011)
NEngl J Med
, vol.365
, pp. 699-708
-
-
Alexander, J.H.1
Lopes, R.D.2
James, S.3
-
11
-
-
84876963408
-
Rivaroxaban in patients stabilized after a ST-elevation myocardial infarction: results from the ATLAS ACS 2-TIMI 51 trial
-
Mega J.L., Braunwald E., Murphy S.A., et al. Rivaroxaban in patients stabilized after a ST-elevation myocardial infarction: results from the ATLAS ACS 2-TIMI 51 trial. JAm Coll Cardiol 2013, 61:1853-1859.
-
(2013)
JAm Coll Cardiol
, vol.61
, pp. 1853-1859
-
-
Mega, J.L.1
Braunwald, E.2
Murphy, S.A.3
-
12
-
-
34548575058
-
Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: a randomised, double-blind, non-inferiority trial
-
Eriksson B.I., Dahl O.E., Rosencher N., et al. Dabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: a randomised, double-blind, non-inferiority trial. Lancet 2007, 370:949-956.
-
(2007)
Lancet
, vol.370
, pp. 949-956
-
-
Eriksson, B.I.1
Dahl, O.E.2
Rosencher, N.3
-
13
-
-
79953836474
-
Oral dabigatran versus enoxaparin for thromboprophylaxis after primary total hip arthroplasty (RE-NOVATE II*). A randomised, double-blind, non-inferiority trial
-
Eriksson B.I., Dahl O.E., Huo M.H., et al. Oral dabigatran versus enoxaparin for thromboprophylaxis after primary total hip arthroplasty (RE-NOVATE II*). A randomised, double-blind, non-inferiority trial. Thromb Haemost 2011, 105:721-729.
-
(2011)
Thromb Haemost
, vol.105
, pp. 721-729
-
-
Eriksson, B.I.1
Dahl, O.E.2
Huo, M.H.3
-
14
-
-
45949099359
-
Rivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty
-
Eriksson B.I., Borris L.C., Friedman R.J., et al. Rivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty. NEngl J Med 2008, 358:2765-2775.
-
(2008)
NEngl J Med
, vol.358
, pp. 2765-2775
-
-
Eriksson, B.I.1
Borris, L.C.2
Friedman, R.J.3
-
15
-
-
46049106502
-
Extended duration rivaroxaban versus short-term enoxaparin for the prevention of venous thromboembolism after total hip arthroplasty: a double-blind, randomised controlled trial
-
Kakkar A.K., Brenner B., Dahl O.E., et al. Extended duration rivaroxaban versus short-term enoxaparin for the prevention of venous thromboembolism after total hip arthroplasty: a double-blind, randomised controlled trial. Lancet 2008, 372:31-39.
-
(2008)
Lancet
, vol.372
, pp. 31-39
-
-
Kakkar, A.K.1
Brenner, B.2
Dahl, O.E.3
-
16
-
-
78650587760
-
Apixaban versus enoxaparin for thromboprophylaxis after hip replacement
-
Lassen M.R., Gallus A., Raskob G.E., et al. Apixaban versus enoxaparin for thromboprophylaxis after hip replacement. NEngl J Med 2010, 363:2487-2498.
-
(2010)
NEngl J Med
, vol.363
, pp. 2487-2498
-
-
Lassen, M.R.1
Gallus, A.2
Raskob, G.E.3
-
17
-
-
57649123692
-
Oral thrombin inhibitor dabigatran etexilate vs North American enoxaparin regimen for prevention of venous thromboembolism after knee arthroplasty surgery
-
Ginsberg J.S., Davidson B.L., Comp P.C., et al. Oral thrombin inhibitor dabigatran etexilate vs North American enoxaparin regimen for prevention of venous thromboembolism after knee arthroplasty surgery. JArthroplasty 2009, 24:1-9.
-
(2009)
JArthroplasty
, vol.24
, pp. 1-9
-
-
Ginsberg, J.S.1
Davidson, B.L.2
Comp, P.C.3
-
18
-
-
35449007749
-
Oral dabigatran etexilate vs. subcutaneous enoxaparin for the prevention of venous thromboembolism after total knee replacement: the RE-MODEL randomized trial
-
Eriksson B.I., Dahl O.E., Rosencher N., et al. Oral dabigatran etexilate vs. subcutaneous enoxaparin for the prevention of venous thromboembolism after total knee replacement: the RE-MODEL randomized trial. JThromb Haemost 2007, 5:2178-2185.
-
(2007)
JThromb Haemost
, vol.5
, pp. 2178-2185
-
-
Eriksson, B.I.1
Dahl, O.E.2
Rosencher, N.3
-
19
-
-
45949103416
-
Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty
-
Lassen M.R., Ageno W., Borris L.C., et al. Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty. NEngl J Med 2008, 358:2776-2786.
-
(2008)
NEngl J Med
, vol.358
, pp. 2776-2786
-
-
Lassen, M.R.1
Ageno, W.2
Borris, L.C.3
-
20
-
-
65549169515
-
Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty (RECORD4): a randomised trial
-
Turpie A.G., Lassen M.R., Davidson B.L., et al. Rivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty (RECORD4): a randomised trial. Lancet 2009, 373:1673-1680.
-
(2009)
Lancet
, vol.373
, pp. 1673-1680
-
-
Turpie, A.G.1
Lassen, M.R.2
Davidson, B.L.3
-
21
-
-
68249158084
-
Apixaban or enoxaparin for thromboprophylaxis after knee replacement
-
Lassen M.R., Raskob G.E., Gallus A., et al. Apixaban or enoxaparin for thromboprophylaxis after knee replacement. NEngl J Med 2009, 361:594-604.
-
(2009)
NEngl J Med
, vol.361
, pp. 594-604
-
-
Lassen, M.R.1
Raskob, G.E.2
Gallus, A.3
-
22
-
-
77649113258
-
Apixaban versus enoxaparin for thromboprophylaxis after knee replacement (ADVANCE-2): a randomised double-blind trial
-
Lassen M.R., Raskob G.E., Gallus A., et al. Apixaban versus enoxaparin for thromboprophylaxis after knee replacement (ADVANCE-2): a randomised double-blind trial. Lancet 2010, 375:807-815.
-
(2010)
Lancet
, vol.375
, pp. 807-815
-
-
Lassen, M.R.1
Raskob, G.E.2
Gallus, A.3
-
23
-
-
83155193223
-
Apixaban versus enoxaparin for thromboprophylaxis in medically ill patients
-
Goldhaber S.Z., Leizorovicz A., Kakkar A.K., et al. Apixaban versus enoxaparin for thromboprophylaxis in medically ill patients. NEngl J Med 2011, 365:2167-2177.
-
(2011)
NEngl J Med
, vol.365
, pp. 2167-2177
-
-
Goldhaber, S.Z.1
Leizorovicz, A.2
Kakkar, A.K.3
-
24
-
-
84873514413
-
Rivaroxaban for thromboprophylaxis in acutely ill medical patients
-
Cohen A.T., Spiro T.E., Buller H.R., et al. Rivaroxaban for thromboprophylaxis in acutely ill medical patients. NEngl J Med 2013, 368:513-523.
-
(2013)
NEngl J Med
, vol.368
, pp. 513-523
-
-
Cohen, A.T.1
Spiro, T.E.2
Buller, H.R.3
-
25
-
-
71849117615
-
Dabigatran versus warfarin in the treatment of acute venous thromboembolism
-
Schulman S., Kearon C., Kakkar A.K., et al. Dabigatran versus warfarin in the treatment of acute venous thromboembolism. NEngl J Med 2009, 361:2342-2352.
-
(2009)
NEngl J Med
, vol.361
, pp. 2342-2352
-
-
Schulman, S.1
Kearon, C.2
Kakkar, A.K.3
-
26
-
-
84862530985
-
ARandomized Trial of Dabigatran Versus Warfarin in the Treatment of Acute Venous Thromboembolism (RE-COVER II)
-
abstract 205
-
Schulman S., Kakkar A., Schellong S., et al. ARandomized Trial of Dabigatran Versus Warfarin in the Treatment of Acute Venous Thromboembolism (RE-COVER II). Proc ASH 2011, abstract 205.
-
(2011)
Proc ASH
-
-
Schulman, S.1
Kakkar, A.2
Schellong, S.3
-
27
-
-
84874003257
-
Extended use of dabigatran, warfarin, or placebo in venous thromboembolism
-
Schulman S., Kearon C., Kakkar A.K., et al. Extended use of dabigatran, warfarin, or placebo in venous thromboembolism. NEngl J Med 2013, 368:709-718.
-
(2013)
NEngl J Med
, vol.368
, pp. 709-718
-
-
Schulman, S.1
Kearon, C.2
Kakkar, A.K.3
-
28
-
-
78650619315
-
Oral rivaroxaban for symptomatic venous thromboembolism
-
Bauersachs R., Berkowitz S.D., Brenner B., et al. Oral rivaroxaban for symptomatic venous thromboembolism. NEngl J Med 2010, 363:2499-2510.
-
(2010)
NEngl J Med
, vol.363
, pp. 2499-2510
-
-
Bauersachs, R.1
Berkowitz, S.D.2
Brenner, B.3
-
29
-
-
84873596181
-
Apixaban for extended treatment of venous thromboembolism
-
Agnelli G., Buller H.R., Cohen A., et al. Apixaban for extended treatment of venous thromboembolism. NEngl J Med 2013, 368:699-708.
-
(2013)
NEngl J Med
, vol.368
, pp. 699-708
-
-
Agnelli, G.1
Buller, H.R.2
Cohen, A.3
-
30
-
-
84859385808
-
Oral rivaroxaban for the treatment of symptomatic pulmonary embolism
-
Buller H.R., Prins M.H., Lensin A.W., et al. Oral rivaroxaban for the treatment of symptomatic pulmonary embolism. NEngl J Med 2012, 366:1287-1297.
-
(2012)
NEngl J Med
, vol.366
, pp. 1287-1297
-
-
Buller, H.R.1
Prins, M.H.2
Lensin, A.W.3
-
31
-
-
84861616750
-
Intracranial hemorrhage in atrial fibrillation patients during anticoagulation with warfarin or dabigatran: the RE-LY trial
-
Hart R.G., Diener H.C., Yang S., et al. Intracranial hemorrhage in atrial fibrillation patients during anticoagulation with warfarin or dabigatran: the RE-LY trial. Stroke 2012, 43:1511-1517.
-
(2012)
Stroke
, vol.43
, pp. 1511-1517
-
-
Hart, R.G.1
Diener, H.C.2
Yang, S.3
-
32
-
-
84856784474
-
Oral anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
-
Ageno W., Gallus A.S., Wittkowsky A., et al. Oral anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012, 141:e44S-e88S.
-
(2012)
Chest
, vol.141
-
-
Ageno, W.1
Gallus, A.S.2
Wittkowsky, A.3
-
33
-
-
19344366484
-
Systematic overview of warfarin and its drug and food interactions
-
Holbrook A.M., Pereira J.A., Labiris R., et al. Systematic overview of warfarin and its drug and food interactions. Arch Intern Med 2005, 165:1095-1106.
-
(2005)
Arch Intern Med
, vol.165
, pp. 1095-1106
-
-
Holbrook, A.M.1
Pereira, J.A.2
Labiris, R.3
-
34
-
-
77952728946
-
Twelve-month outcomes and predictors of very stable INR control in prevalent warfarin users
-
Witt D.M., Delate T., Clark N.P., et al. Twelve-month outcomes and predictors of very stable INR control in prevalent warfarin users. JThromb Haemost 2010, 8:744-749.
-
(2010)
JThromb Haemost
, vol.8
, pp. 744-749
-
-
Witt, D.M.1
Delate, T.2
Clark, N.P.3
-
35
-
-
54049092455
-
Predictors of outcome in warfarin-related intracerebral hemorrhage
-
Zubkov A.Y., Mandrekar J.N., Claassen D.O., et al. Predictors of outcome in warfarin-related intracerebral hemorrhage. Arch Neurol 2008, 65:1320-1325.
-
(2008)
Arch Neurol
, vol.65
, pp. 1320-1325
-
-
Zubkov, A.Y.1
Mandrekar, J.N.2
Claassen, D.O.3
-
36
-
-
70349254549
-
Outcomes and predictors of very stable INR control during chronic anticoagulation therapy
-
Witt D.M., Delate T., Clark N.P., et al. Outcomes and predictors of very stable INR control during chronic anticoagulation therapy. Blood 2009, 114:952-956.
-
(2009)
Blood
, vol.114
, pp. 952-956
-
-
Witt, D.M.1
Delate, T.2
Clark, N.P.3
-
37
-
-
0028343127
-
Risk factors for intracranial hemorrhage in outpatients taking warfarin
-
Hylek E.M., Singer D.E. Risk factors for intracranial hemorrhage in outpatients taking warfarin. Ann Intern Med 1994, 120:897-902.
-
(1994)
Ann Intern Med
, vol.120
, pp. 897-902
-
-
Hylek, E.M.1
Singer, D.E.2
-
38
-
-
0027531953
-
Amethod to determine the optimal intensity of oral anticoagulant therapy
-
Rosendaal F.R., Cannegieter S.C., van der Meer F.J., et al. Amethod to determine the optimal intensity of oral anticoagulant therapy. Thromb Haemost 1993, 69:236-239.
-
(1993)
Thromb Haemost
, vol.69
, pp. 236-239
-
-
Rosendaal, F.R.1
Cannegieter, S.C.2
van der Meer, F.J.3
-
39
-
-
57149140461
-
Benefit of oral anticoagulant over antiplatelet therapy in atrial fibrillation depends on the quality of international normalized ratio control achieved by centers and countries as measured by time in therapeutic range
-
Connolly S.J., Pogue J., Eikelboom J., et al. Benefit of oral anticoagulant over antiplatelet therapy in atrial fibrillation depends on the quality of international normalized ratio control achieved by centers and countries as measured by time in therapeutic range. Circulation 2008, 118:2029-2037.
-
(2008)
Circulation
, vol.118
, pp. 2029-2037
-
-
Connolly, S.J.1
Pogue, J.2
Eikelboom, J.3
-
40
-
-
84868589319
-
Variation in warfarin dose adjustment practice is responsible for differences in the quality of anticoagulation control between centers and countries: an analysis of patients receiving warfarin in the randomized evaluation of long-term anticoagulation therapy (RE-LY) trial
-
Van Spall H.G., Wallentin L., Yusuf S., et al. Variation in warfarin dose adjustment practice is responsible for differences in the quality of anticoagulation control between centers and countries: an analysis of patients receiving warfarin in the randomized evaluation of long-term anticoagulation therapy (RE-LY) trial. Circulation 2012, 126:2309-2316.
-
(2012)
Circulation
, vol.126
, pp. 2309-2316
-
-
Van Spall, H.G.1
Wallentin, L.2
Yusuf, S.3
-
41
-
-
84875912864
-
General mechanisms of coagulation and targets of anticoagulants (Section I). Position Paper of the ESC Working Group on Thrombosis-Task Force on Anticoagulants in Heart Disease
-
De Caterina R., Husted S., Wallentin L., et al. General mechanisms of coagulation and targets of anticoagulants (Section I). Position Paper of the ESC Working Group on Thrombosis-Task Force on Anticoagulants in Heart Disease. Thromb Haemost 2013, 109:569-579.
-
(2013)
Thromb Haemost
, vol.109
, pp. 569-579
-
-
De Caterina, R.1
Husted, S.2
Wallentin, L.3
-
42
-
-
84863012587
-
Antithrombotic and thrombolytic therapy for valvular disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
-
Whitlock R.P., Sun J.C., Fremes S.E., Rubens F.D., Teoh K.H. Antithrombotic and thrombolytic therapy for valvular disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012, 141:e576S-e600S.
-
(2012)
Chest
, vol.141
-
-
Whitlock, R.P.1
Sun, J.C.2
Fremes, S.E.3
Rubens, F.D.4
Teoh, K.H.5
-
43
-
-
84944151076
-
Guidelines on the management of valvular heart disease (version 2012): the Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)
-
Vahanian A., Alfieri O., Andreotti F., et al. Guidelines on the management of valvular heart disease (version 2012): the Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Eur J Cardiothorac Surg 2012, 42:S1-S44.
-
(2012)
Eur J Cardiothorac Surg
, vol.42
-
-
Vahanian, A.1
Alfieri, O.2
Andreotti, F.3
-
44
-
-
84875938323
-
Genetic determinants of dabigatran plasma levels and their relation to bleeding
-
Pare G., Eriksson N., Lehr T., et al. Genetic determinants of dabigatran plasma levels and their relation to bleeding. Circulation 2013, 127:1404-1412.
-
(2013)
Circulation
, vol.127
, pp. 1404-1412
-
-
Pare, G.1
Eriksson, N.2
Lehr, T.3
-
45
-
-
84879508542
-
-
Xarelto (rivaroxaban). Product information. Bayer AG, Leverkusen, Germany. Available at: Accessed May 22
-
Xarelto (rivaroxaban). Product information. Bayer AG, Leverkusen, Germany. Available at: Accessed May 22, 2013. http://www.bayer.ca/files/Xarelto%20English%2012APR2013.pdf?
-
(2013)
-
-
-
46
-
-
84879533001
-
-
Eliquis (apixaban). Product information. Bristol-Myers Squibb Co, Princeton, NJ. Available at: Accessed May 22
-
Eliquis (apixaban). Product information. Bristol-Myers Squibb Co, Princeton, NJ. Available at: Accessed May 22, 2013. http://www.pfizer.ca/en/our_products/products/monograph/313.
-
(2013)
-
-
-
47
-
-
84879545980
-
-
PRADAXA (dabigatran etexilate mesylate). Product information. Boehringer Ingelheim Pharmaceuticals, Inc, Ridgefield, CT. Available at: Accessed May 22
-
PRADAXA (dabigatran etexilate mesylate). Product information. Boehringer Ingelheim Pharmaceuticals, Inc, Ridgefield, CT. Available at: Accessed May 22, 2013. http://www.boehringer-ingelheim.ca/content/dam/internet/opu/ca_EN/documents/humanhealth/product_monograph/Pradax-pm.pdf.
-
(2013)
-
-
-
48
-
-
78649980897
-
Pharmacologic properties of the new oral anticoagulants: a clinician-oriented review with a focus on perioperative management
-
Douketis J.D. Pharmacologic properties of the new oral anticoagulants: a clinician-oriented review with a focus on perioperative management. Curr Pharm Des 2010, 16:3436-3441.
-
(2010)
Curr Pharm Des
, vol.16
, pp. 3436-3441
-
-
Douketis, J.D.1
-
49
-
-
77953168824
-
Dabigatran etexilate-a novel, reversible, oral direct thrombin inhibitor: interpretation of coagulation assays and reversal of anticoagulant activity
-
van Ryn J., Stangier J., Haertter S., et al. Dabigatran etexilate-a novel, reversible, oral direct thrombin inhibitor: interpretation of coagulation assays and reversal of anticoagulant activity. Thromb Haemost 2010, 103:1116-1127.
-
(2010)
Thromb Haemost
, vol.103
, pp. 1116-1127
-
-
van Ryn, J.1
Stangier, J.2
Haertter, S.3
-
50
-
-
84856593171
-
Using the HEMOCLOT direct thrombin inhibitor assay to determine plasma concentrations of dabigatran
-
Stangier J., Feuring M. Using the HEMOCLOT direct thrombin inhibitor assay to determine plasma concentrations of dabigatran. Blood Coagul Fibrinolysis 2012, 23:138-143.
-
(2012)
Blood Coagul Fibrinolysis
, vol.23
, pp. 138-143
-
-
Stangier, J.1
Feuring, M.2
-
51
-
-
78649736882
-
Clinical laboratory measurement of direct factor Xa inhibitors: anti-Xa assay is preferable to prothrombin time assay
-
Barrett Y.C., Wang Z., Frost C., Shenker A. Clinical laboratory measurement of direct factor Xa inhibitors: anti-Xa assay is preferable to prothrombin time assay. Thromb Haemost 2010, 104:1263-1271.
-
(2010)
Thromb Haemost
, vol.104
, pp. 1263-1271
-
-
Barrett, Y.C.1
Wang, Z.2
Frost, C.3
Shenker, A.4
-
52
-
-
84863679656
-
Accurate determination of rivaroxaban levels requires different calibrator sets but not addition of antithrombin
-
Mani H., Rohde G., Stratmann G., et al. Accurate determination of rivaroxaban levels requires different calibrator sets but not addition of antithrombin. Thromb Haemost 2012, 108:191-198.
-
(2012)
Thromb Haemost
, vol.108
, pp. 191-198
-
-
Mani, H.1
Rohde, G.2
Stratmann, G.3
-
53
-
-
84856632988
-
Evaluation of the anti-factor Xa chromogenic assay for the measurement of rivaroxaban plasma concentrations using calibrators and controls
-
Samama M.M., Contant G., Spiro T.E., et al. Evaluation of the anti-factor Xa chromogenic assay for the measurement of rivaroxaban plasma concentrations using calibrators and controls. Thromb Haemost 2012, 107:379-387.
-
(2012)
Thromb Haemost
, vol.107
, pp. 379-387
-
-
Samama, M.M.1
Contant, G.2
Spiro, T.E.3
-
54
-
-
84873326583
-
Rates of hemorrhage during warfarin therapy for atrial fibrillation
-
Gomes T., Mamdani M.M., Holbrook A.M., et al. Rates of hemorrhage during warfarin therapy for atrial fibrillation. CMAJ 2013, 185:E121-E127.
-
(2013)
CMAJ
, vol.185
-
-
Gomes, T.1
Mamdani, M.M.2
Holbrook, A.M.3
-
55
-
-
84869189977
-
Periprocedural management and approach to bleeding in patients taking dabigatran
-
Weitz J.I., Quinlan D.J., Eikelboom J.W. Periprocedural management and approach to bleeding in patients taking dabigatran. Circulation 2012, 126:2428-2432.
-
(2012)
Circulation
, vol.126
, pp. 2428-2432
-
-
Weitz, J.I.1
Quinlan, D.J.2
Eikelboom, J.W.3
-
56
-
-
33644592680
-
Treatment of excessive anticoagulation with phytonadione (vitamin K): a meta-analysis
-
Dezee K.J., Shimeall W.T., Douglas K.M., Shumway N.M., O'Malley P.G. Treatment of excessive anticoagulation with phytonadione (vitamin K): a meta-analysis. Arch Intern Med 2006, 166:391-397.
-
(2006)
Arch Intern Med
, vol.166
, pp. 391-397
-
-
Dezee, K.J.1
Shimeall, W.T.2
Douglas, K.M.3
Shumway, N.M.4
O'Malley, P.G.5
-
57
-
-
84874376350
-
Warfarin-related intracerebral haemorrhage: better outcomes when reversal includes prothrombin complex concentrates
-
Hanger H.C., Geddes J.A., Wilkinson T.J., Lee M., Baker A.E. Warfarin-related intracerebral haemorrhage: better outcomes when reversal includes prothrombin complex concentrates. Intern Med J 2013, 43:308-316.
-
(2013)
Intern Med J
, vol.43
, pp. 308-316
-
-
Hanger, H.C.1
Geddes, J.A.2
Wilkinson, T.J.3
Lee, M.4
Baker, A.E.5
-
58
-
-
33745141580
-
Hematoma growth and outcome in treated neurocritical care patients with intracerebral hemorrhage related to oral anticoagulant therapy: comparison of acute treatment strategies using vitamin K, fresh frozen plasma, and prothrombin complex concentrates
-
Huttner H.B., Schellinger P.D., Hartmann M., et al. Hematoma growth and outcome in treated neurocritical care patients with intracerebral hemorrhage related to oral anticoagulant therapy: comparison of acute treatment strategies using vitamin K, fresh frozen plasma, and prothrombin complex concentrates. Stroke 2006, 37:1465-1470.
-
(2006)
Stroke
, vol.37
, pp. 1465-1470
-
-
Huttner, H.B.1
Schellinger, P.D.2
Hartmann, M.3
-
59
-
-
84879518063
-
Rapid warfarin reversal in the setting of intracranial hemorrhage: a comparison of plasma, recombinant activated factor VII, and prothrombin complex concentrate
-
[Epub ahead of print]
-
Woo C.H., Patel N., Conell C., et al. Rapid warfarin reversal in the setting of intracranial hemorrhage: a comparison of plasma, recombinant activated factor VII, and prothrombin complex concentrate. World Neurosurg 2012, [Epub ahead of print].
-
(2012)
World Neurosurg
-
-
Woo, C.H.1
Patel, N.2
Conell, C.3
-
60
-
-
84879548455
-
Aspecific antidote for dabigatran: functional and structural characterization
-
Schiele F., van Ryn J., Canada K., et al. Aspecific antidote for dabigatran: functional and structural characterization. Blood 2013, 121:3554-3562.
-
(2013)
Blood
, vol.121
, pp. 3554-3562
-
-
Schiele, F.1
van Ryn, J.2
Canada, K.3
-
61
-
-
84878460192
-
Aspecific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor Xa
-
Lu G., Deguzman F.R., Hollenbach S.J., et al. Aspecific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor Xa. Nat Med 2013, 19:446-451.
-
(2013)
Nat Med
, vol.19
, pp. 446-451
-
-
Lu, G.1
Deguzman, F.R.2
Hollenbach, S.J.3
-
63
-
-
84876288671
-
Hemostatic therapy in experimental intracerebral hemorrhage associated with rivaroxaban
-
Zhou W., Zorn M., Nawroth P., et al. Hemostatic therapy in experimental intracerebral hemorrhage associated with rivaroxaban. Stroke 2013, 44:771-778.
-
(2013)
Stroke
, vol.44
, pp. 771-778
-
-
Zhou, W.1
Zorn, M.2
Nawroth, P.3
-
64
-
-
84655176578
-
Evaluation of prothrombin complex concentrate and recombinant activated factor VII to reverse rivaroxaban in a rabbit model
-
Godier A., Miclot A., Le Bonniec B., et al. Evaluation of prothrombin complex concentrate and recombinant activated factor VII to reverse rivaroxaban in a rabbit model. Anesthesiology 2012, 116:94-102.
-
(2012)
Anesthesiology
, vol.116
, pp. 94-102
-
-
Godier, A.1
Miclot, A.2
Le Bonniec, B.3
-
65
-
-
84870835456
-
Haemostatic response to invitro addition of recombinant factor VIla, prothrombin complex concentrate, or concentrate of factor IX/X in blood spiked with a direct Xa inhibitor
-
Olesen J.B., Christiansen K., Ingerslev J., Sørensen B., Hvas A. Haemostatic response to invitro addition of recombinant factor VIla, prothrombin complex concentrate, or concentrate of factor IX/X in blood spiked with a direct Xa inhibitor. JThromb Haemost 2009, 7(suppl 2):448.
-
(2009)
JThromb Haemost
, vol.7
, Issue.SUPPL. 2
, pp. 448
-
-
Olesen, J.B.1
Christiansen, K.2
Ingerslev, J.3
Sørensen, B.4
Hvas, A.5
-
66
-
-
84879549154
-
Potential of activated prothrombin complex concentrate and activated factor VII to reverse the anticoagulant effects of rivaroxaban in primates
-
Paper presented at: 50th Annual Meeting and Exposition of the American Society of Hematology. December 5-9, San Francisco, CA.
-
Gruber A, Marzec U, Buetehorn U, Hanson S, Perzborn E. Potential of activated prothrombin complex concentrate and activated factor VII to reverse the anticoagulant effects of rivaroxaban in primates. Paper presented at: 50th Annual Meeting and Exposition of the American Society of Hematology. December 5-9, 2008; San Francisco, CA.
-
(2008)
-
-
Gruber, A.1
Marzec, U.2
Buetehorn, U.3
Hanson, S.4
Perzborn, E.5
-
67
-
-
84858755308
-
The successful reversal of dabigatran-induced bleeding by coagulation factor concentrates in a rat tail bleeding model do not correlate with exvivo markers of anticoagulation
-
abstract 2316
-
van Ryn J., Schurer J., Kink-Eiband M., Clemens A. The successful reversal of dabigatran-induced bleeding by coagulation factor concentrates in a rat tail bleeding model do not correlate with exvivo markers of anticoagulation. Blood 2011, 118. abstract 2316.
-
(2011)
Blood
, vol.118
-
-
van Ryn, J.1
Schurer, J.2
Kink-Eiband, M.3
Clemens, A.4
-
68
-
-
80053464592
-
Beriplex P/N reverses bleeding in an acute renal injury model after dabigatran overdose in rabbits
-
Pragst I., Dörr B., Kaspereit F., et al. Beriplex P/N reverses bleeding in an acute renal injury model after dabigatran overdose in rabbits. Pathophysiol Haemost Thromb 2010, 37:A94.
-
(2010)
Pathophysiol Haemost Thromb
, vol.37
-
-
Pragst, I.1
Dörr, B.2
Kaspereit, F.3
-
69
-
-
67849124919
-
Reversibility of the anticoagulation effect of high doses of the direct thrombin inhibitor dabigatran, by recombinant factor VIIa or activated prothrombin complex concentrate
-
148 abstract 0370
-
van Ryn J., Ruehl D., Priepke H., Hauel N., Wienen W. Reversibility of the anticoagulation effect of high doses of the direct thrombin inhibitor dabigatran, by recombinant factor VIIa or activated prothrombin complex concentrate. Haematologica 2008, 93(suppl 1). 148 abstract 0370.
-
(2008)
Haematologica
, vol.93
, Issue.SUPPL. 1
-
-
van Ryn, J.1
Ruehl, D.2
Priepke, H.3
Hauel, N.4
Wienen, W.5
-
70
-
-
80053571188
-
Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo-controlled, crossover study in healthy subjects
-
Eerenberg E.S., Kamphuisen P.W., Sijpkens M.K., et al. Reversal of rivaroxaban and dabigatran by prothrombin complex concentrate: a randomized, placebo-controlled, crossover study in healthy subjects. Circulation 2011, 124:1573-1579.
-
(2011)
Circulation
, vol.124
, pp. 1573-1579
-
-
Eerenberg, E.S.1
Kamphuisen, P.W.2
Sijpkens, M.K.3
-
71
-
-
84879509811
-
Coagulation factor concentrates restore alterations in hemostasis induced by a high dose of apixaban: studies invitro with circulating human blood
-
Paper presented at: 54th Annual Meeting of the American Society of Hematology. December 8-11,; Atlanta, GA.
-
Escolar G, Arellano-Rodrigo E, Carles Reverter J, et al. Coagulation factor concentrates restore alterations in hemostasis induced by a high dose of apixaban: studies invitro with circulating human blood. Paper presented at: 54th Annual Meeting of the American Society of Hematology. December 8-11, 2012; Atlanta, GA.
-
(2012)
-
-
Escolar, G.1
Arellano-Rodrigo, E.2
Carles Reverter, J.3
-
72
-
-
84864370719
-
Effect of non-specific reversal agents on anticoagulant activity of dabigatran and rivaroxaban: a randomised crossover exvivo study in healthy volunteers
-
Marlu R., Hodaj E., Paris A., et al. Effect of non-specific reversal agents on anticoagulant activity of dabigatran and rivaroxaban: a randomised crossover exvivo study in healthy volunteers. Thromb Haemost 2012, 108:217-224.
-
(2012)
Thromb Haemost
, vol.108
, pp. 217-224
-
-
Marlu, R.1
Hodaj, E.2
Paris, A.3
-
73
-
-
64549121235
-
Recombinant factor VIIa partially reverses the anticoagulant effect of high-dose rivaroxaban - a novel, oral, direct factor Xa inhibitor-in rats
-
abstract P-W-652.
-
Tinel H., Huetter J., Perzborn E. Recombinant factor VIIa partially reverses the anticoagulant effect of high-dose rivaroxaban - a novel, oral, direct factor Xa inhibitor-in rats. JThromb Haemost 2007, 5(suppl 2). abstract P-W-652.
-
(2007)
JThromb Haemost
, vol.5
, Issue.SUPPL. 2
-
-
Tinel, H.1
Huetter, J.2
Perzborn, E.3
-
74
-
-
84867344952
-
Reversal of dabigatran-induced bleeding with a prothrombin complex concentrate and fresh frozen plasma
-
Dumkow L.E., Voss J.R., Peters M., Jennings D.L. Reversal of dabigatran-induced bleeding with a prothrombin complex concentrate and fresh frozen plasma. Am J Health Syst Pharm 2012, 69:1646-1650.
-
(2012)
Am J Health Syst Pharm
, vol.69
, pp. 1646-1650
-
-
Dumkow, L.E.1
Voss, J.R.2
Peters, M.3
Jennings, D.L.4
-
75
-
-
79958288215
-
Adsorption of dabigatran etexilate in water or dabigatran in pooled human plasma by activated charcoal invitro
-
van Ryn J., Sieger P., Kink-Eiband M., Gansser D., Clemens A. Adsorption of dabigatran etexilate in water or dabigatran in pooled human plasma by activated charcoal invitro. Blood 2009, 114:22.
-
(2009)
Blood
, vol.114
, pp. 22
-
-
van Ryn, J.1
Sieger, P.2
Kink-Eiband, M.3
Gansser, D.4
Clemens, A.5
-
76
-
-
84878106189
-
Positive outcome after intentional overdose of dabigatran
-
Woo J.S., Kapadia N., Phanco S.E., Lynch C.A. Positive outcome after intentional overdose of dabigatran. JMed Toxicol 2013, 9:192-195.
-
(2013)
JMed Toxicol
, vol.9
, pp. 192-195
-
-
Woo, J.S.1
Kapadia, N.2
Phanco, S.E.3
Lynch, C.A.4
-
77
-
-
77949421739
-
Influence of renal impairment on the pharmacokinetics and pharmacodynamics of oral dabigatran etexilate: an open-label, parallel-group, single-centre study
-
Stangier J., Rathgen K., Stahle H., Mazur D. Influence of renal impairment on the pharmacokinetics and pharmacodynamics of oral dabigatran etexilate: an open-label, parallel-group, single-centre study. Clin Pharmacokinet 2010, 49:259-268.
-
(2010)
Clin Pharmacokinet
, vol.49
, pp. 259-268
-
-
Stangier, J.1
Rathgen, K.2
Stahle, H.3
Mazur, D.4
-
78
-
-
84875926001
-
Effective elimination of dabigatran by haemodialysis. A phase I single-centre study in patients with end-stage renal disease
-
Khadzhynov D., Wagner F., Formella S., et al. Effective elimination of dabigatran by haemodialysis. A phase I single-centre study in patients with end-stage renal disease. Thromb Haemost 2013, 109:596-605.
-
(2013)
Thromb Haemost
, vol.109
, pp. 596-605
-
-
Khadzhynov, D.1
Wagner, F.2
Formella, S.3
-
79
-
-
84870776429
-
Successful removal of dabigatran in flowing blood with an activated charcoal hemoperfusion column in an invitro test system [abstract 0700]
-
Van Ryn J., Neubauer M., Flieg R., et al. Successful removal of dabigatran in flowing blood with an activated charcoal hemoperfusion column in an invitro test system [abstract 0700]. Haematologica 2010, 95(suppl 2):293.
-
(2010)
Haematologica
, vol.95
, Issue.SUPPL. 2
, pp. 293
-
-
Van Ryn, J.1
Neubauer, M.2
Flieg, R.3
-
80
-
-
84879523730
-
Treatment of acute stroke in patients on dabigatran: a survey of US stroke specialists
-
[Epub ahead of print]
-
Rybinnik I., Mullen M.T., Messe S., Kasner S.E., Cucchiara B. Treatment of acute stroke in patients on dabigatran: a survey of US stroke specialists. JStroke Cerebrovasc Dis 2013, [Epub ahead of print].
-
(2013)
JStroke Cerebrovasc Dis
-
-
Rybinnik, I.1
Mullen, M.T.2
Messe, S.3
Kasner, S.E.4
Cucchiara, B.5
-
81
-
-
84877743192
-
Treatment of bleeding complications when using oral anticoagulants for prevention of strokes
-
Akwaa F., Spyropoulos A.C. Treatment of bleeding complications when using oral anticoagulants for prevention of strokes. Curr Treat Options Cardiovasc Med 2013, 15:288-298.
-
(2013)
Curr Treat Options Cardiovasc Med
, vol.15
, pp. 288-298
-
-
Akwaa, F.1
Spyropoulos, A.C.2
-
82
-
-
84876681725
-
Reversal of novel oral anticoagulants in patients with major bleeding
-
Siegal D.M., Cuker A. Reversal of novel oral anticoagulants in patients with major bleeding. JThromb Thrombolysis 2013, 35:391-398.
-
(2013)
JThromb Thrombolysis
, vol.35
, pp. 391-398
-
-
Siegal, D.M.1
Cuker, A.2
-
83
-
-
84867289249
-
Management of bleeding in patients receiving conventional or new anticoagulants: a practical and case-based approach
-
Donadini M.P., Ageno W., Douketis J.D. Management of bleeding in patients receiving conventional or new anticoagulants: a practical and case-based approach. Drugs 2012, 72:1965-1975.
-
(2012)
Drugs
, vol.72
, pp. 1965-1975
-
-
Donadini, M.P.1
Ageno, W.2
Douketis, J.D.3
-
84
-
-
84859971855
-
Guidance on the emergent reversal of oral thrombin and factor Xa inhibitors
-
Kaatz S., Kouides P.A., Garcia D.A., et al. Guidance on the emergent reversal of oral thrombin and factor Xa inhibitors. Am J Hematol 2012, 87(suppl 1):S141-S145.
-
(2012)
Am J Hematol
, vol.87
, Issue.SUPPL. 1
-
-
Kaatz, S.1
Kouides, P.A.2
Garcia, D.A.3
|