Repeated whole cigarette smoke exposure alters cell differentiation and augments secretion of inflammatory mediators in air-liquid interface three-dimensional co-culture model of human bronchial tissue

Toxicology in Vitro

Volumn 38, Issue , 2017, Pages 170-178

  Ishikawa, Shinkichi ^a   Ito, Shigeaki ^a  

^a JAPAN TOBACCO INC   (Japan)

Author keywords

Air liquid interface culture; Co culture; Inflammation; Respiratory epithelium; Three dimensional culture; Whole cigarette smoke

Indexed keywords

CIGARETTE SMOKE; COLLAGEN; CXCL1 CHEMOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1BETA; INTERLEUKIN 8; CYTOCHROME P450 1A1; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; SMOKE;

AIRWAY EPITHELIUM CELL; ARTICLE; BRONCHITIS; BRONCHUS EPITHELIUM; BRONCHUS TISSUE; CELL DIFFERENTIATION; CILIATED EPITHELIUM CELL; COCULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY TEST; EXPOSURE; FETUS; GENE EXPRESSION REGULATION; GOBLET CELL; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LUNG FIBROBLAST; PROTEIN EXPRESSION; TISSUE CULTURE; UPREGULATION; ADVERSE EFFECTS; BRONCHUS; CYTOLOGY; DRUG EFFECTS; EPITHELIUM CELL; FIBROBLAST; GENE EXPRESSION; GENETICS; METABOLISM; SMOKE; TISSUE CULTURE TECHNIQUE; TOBACCO;

BRONCHI; CELL DIFFERENTIATION; COCULTURE TECHNIQUES; CYTOCHROME P-450 CYP1A1; CYTOKINES; EPITHELIAL CELLS; FIBROBLASTS; GENE EXPRESSION; HUMANS; NF-KAPPA B; SMOKE; TISSUE CULTURE TECHNIQUES; TOBACCO;

EID: 84992034937     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2016.09.004     Document Type: Article

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