Differentiation of human airway epithelia is dependent on erbB2

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 291, Issue 2, 2006, Pages

  Vermeer, Paola D ^a   Panko, Lacey ^a   Karp, Philip ^a   Lee, John H ^b   Zabner, Joseph ^a  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

Author keywords

Fibroblasts; Trastuzumab

Indexed keywords

AMPHIREGULIN; EOSIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIREGULIN; HEMATOXYLIN; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; NEU DIFFERENTIATION FACTOR; TRANSFORMING GROWTH FACTOR ALPHA; TRASTUZUMAB;

ARTICLE; CELL COUNT; CELL DIFFERENTIATION; CELL STRUCTURE; COCULTURE; CONTROLLED STUDY; DRUG MECHANISM; EPITHELIUM CELL; HUMAN; HUMAN CELL; LUNG FIBROBLAST; MORPHOMETRICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; RESPIRATORY EPITHELIUM;

ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; CELL DIFFERENTIATION; CELLS, CULTURED; COCULTURE TECHNIQUES; EPITHELIAL CELLS; FEMALE; FIBROBLASTS; HUMANS; MIDDLE AGED; NEUREGULIN-1; RECEPTOR, ERBB-2; RESPIRATORY MUCOSA;

EID: 33746609721     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00547.2005     Document Type: Article

References (34)

1. Aida S, Tamai S, Sekiguchi S, and Shimizu N. Distribution of epidermal growth factor and epidermal growth factor receptor in human lung: immunohistochemical and immunoelectron-microscopic studies. Respiration 61: 161-166, 1994.
2. Al Moustafa AE, Alaoui-Jamali M, Paterson J, and O'Connor-McCourt M. Expression of P185erbB-2, p160erbB-3, p180erbB-4, and heregulin alpha in human normal bronchial epithelial and lung cancer cell lines. Anticancer Res 19: 481-486, 1999.
3. Baselga J, Norton L, Albanell J, Kim YM, and Mendelsohn J. Recombinant humanized anti-HER2 antibody (Herceptin) enhances the antitumor activity of paclitaxel and doxorubicin against HER2/neu overexpressing human breast cancer xenografts. Cancer Res 58: 2825-2831, 1998.
4. Bishop AE. Pulmonary epithelial stem cells. Cell Prolif 37: 89-96, 2004.
5. Carter P, Presta L, Gorman CM, Ridgway JB, Henner D, Wong WL, Rowland AM, Kotts C, Carver ME, and Shepard HM. Humanization of an anti-p185HER2 antibody for human cancer therapy. Proc Natl Acad Sci USA 89: 4285-4289, 1992.
6. Casalini P, Iorio MV, Galmozzi E, and Menard S. Role of HER receptors family in development and differentiation. J Cell Physiol 200: 343-350, 2004.
7. Choe MM, Sporn PH, and Swartz MA. An in vitro airway wall model of remodeling. Am J Physiol Lung Cell Mol Physiol 285: L427-L433, 2003.
8. Elkin EB, Weinstein MC, Winer EP, Kuntz KM, Schnitt SJ, and Weeks JC. HER-2 testing and trastuzumab therapy for metastatic breast cancer: a cost-effectiveness analysis. J Clin Oncol 22: 854-863, 2004.
9. Fendly BM, Winget M, Hudziak RM, Lipari MT, Napier MA, and Ullrich A. Characterization of murine monoclonal antibodies reactive to either the human epidermal growth factor receptor or HER2/neu gene product. Cancer Res 50: 1550-1558, 1990.
10. Fischer OM, Streit S, Hart S, and Ullrich A. Beyond Herceptin and Gleevec. Curr Opin Chem Biol 7: 490-495, 2003.
11. Gelmon KA, Mackey J, Verma S, Gertler SZ, Bangemann N, Klimo P, Schneeweiss A, Bremer K, Soulieres D, Tonkin K, Bell R, Heinrich B, Grenier D, and Dias R. Use of trastuzumab beyond disease progression: observations from a retrospective review of case histories. Clin Breast Cancer 5: 52-58, 2004.
12. Ginestier C, Charafe-Jauffret E, Penault-Llorca F, Geneix J, Adelaide J, Chaffanet M, Mozziconacci MJ, Hassoun J, Viens P, Birnbaum D, and Jacquemier J. Comparative multi-methodological measurement of ERBB2 status in breast cancer. J Pathol 202: 286-298, 2004.
13. Kalluri R and Neilson EG. Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest 112: 1776-1784, 2003.
14. Kang Y and Massague J. Epithelial-mesenchymal transitions: twist in development and metastasis. Cell 118: 277-279, 2004.
15. Karp PH, Moninger T, Weber SP, Nesselhauf TS, Launspach J, Zabner J, and Welsh MJ. An in vitro model of differentiated human airway epithelia: methods and evaluation of primary cultures. In: Epithelial Cell Culture Protocols, edited by Wise C. Totowa, NJ: Humana, 2002, p. 115-137.
16. Marmor MD, Skaria KB, and Yarden Y. Signal transduction and oncogenesis by ErbB/HER receptors. Int J Radiat Oncol Biol Phys 58: 903-913, 2004.
17. Mio T, Liu XD, Adachi Y, Striz I, Skold CM, Romberger DJ, Spurzem JR, Illig MG, Ertl R, and Rennard SI. Human bronchial epithelial cells modulate collagen gel contraction by fibroblasts. Am J Physiol Lung Cell Mol Physiol 274: L119-L126, 1998.
18. Parmar H and Cunha GR. Epithelial-stromal interactions in the mouse and human mammary gland in vivo. Endocr Relat Cancer 11: 437-458, 2004.
19. Pegram MD, Lipton A, Hayes DF, Weber BL, Baselga JM, Tripathy D, Baly D, Baughman SA, Twaddell T, Glaspy JA, and Slamon DJ. Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment. J Clin Oncol 16: 2659-2671, 1998.
20. Polosa R, Prosperini G, Leir SH, Holgate ST, Lackie PM, and Davies DE. Expression of c-erbB receptors and ligands in human bronchial mucosa. Am J Respir Cell Mol Biol 20: 914-923, 1999.
21. Ranson M and Sliwkowski MX. Perspectives on anti-HER monoclonal antibodies. Oncology 17-24, 2002.
22. Rowinsky EK. The ERBB family: targets for therapeutic development against cancer and therapeutic strategies using monoclonal antibodies and tyrosine kinase inhibitors. Annu Rev Med 433-457, 2004.
23. Sachs LA, Finkbeiner WE, and Widdicombe JH. Effects of media on differentiation of cultured human tracheal epithelium. In Vitro Cell Dev Biol Anim 39: 56-62, 2003.
24. Shen BQ, Panos RJ, Hansen-Guzman K, Widdicombe JH, and Mrsny RJ. Hepatocyte growth factor stimulates the differentiation of human tracheal epithelia in vitro. Am J Physiol Lung Cell Mol Physiol 272: L1115-L1120, 1997.
25. Shimizu T, Takahashi Y, Kawaguchi S, and Sakakura Y. Hypertrophic and metaplastic changes of goblet cells in rat nasal epithelium induced by endotoxin. Am J Respir Crit Care Med 153: 1412-1418, 1996.
26. Smith JJ, Travis SM, Greenberg EP, and Welsh MJ. Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid. Cell 85: 229-236, 1996.
27. Suter TM, Cook-Bruns N, and Barton C. Cardiotoxicity associated with trastuzumab (Herceptin) therapy in the treatment of metastatic breast cancer. Breast 13: 173-183, 2004.
28. Takeyama K, Dabbagh K, Lee HM, Agusti C, Lausier JA, Ueki IF, Grattan KM, and Nadel JA. Epidermal growth factor system regulates mucin production in airways. Proc Natl Acad Sci USA 96: 3081-3086, 1999.
29. Tripathy D, Seiman A, Keefe D, Hudis C, Paton V, and Lieberman G. Effect of cardiac dysfunction on treatment outcomes in women receiving trastuzumab for HER2-overexpressing metastatic breast cancer. Clin Breast Cancer 5: 293-298, 2004.
30. Vermeer PD, Einwalter LA, Moninger T, Rokhlina T, Kern JA, Zabner J, and Welsh M. Segregation of receptor and ligand regulates activation of epithelial growth factor receptor. Nature 422: 322-326, 2003.
31. Weibel ER. Morphometry of the human lung: the state of the art after two decades. Bull Eur Physiopath Respir 15: 999-1013, 1979.
32. Widdicombe JH, Sachs LA, and Finkbeiner WE. Effects of growth surface on differentiation of cultures of human tracheal epithelium. In Vitro Cell Dev Biol Anim 39: 51-55, 2003.
33. Yamaya M, Finkbeiner WE, Chun SY, and Widdicombe JH. Differentiated structure and function of cultures from human tracheal epithelium. Am J Physiol Lung Cell Mol Physiol 262: L713-L724, 1992.
34. - transport in cystic fibrosis airway epithelia in vitro: effect of promoter and administration method. Gene Ther 3: 458-465, 1996.