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Volumn 78, Issue 6, 2016, Pages 1143-1150

Eriocitrin from lemon suppresses the proliferation of human hepatocellular carcinoma cells through inducing apoptosis and arresting cell cycle

Author keywords

Apoptosis; Cell cycle arrest; Eriocitrin; Hepatocellular carcinoma

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 1; ANTIMITOTIC AGENT; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 7; CASPASE 9; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIN A; CYCLIN D3; CYCLIN DEPENDENT KINASE 6; ERIOCITRIN; FLAVONOID; PROTEIN P53; UNCLASSIFIED DRUG; ATF1 PROTEIN, HUMAN; CASPASE; CREB1 PROTEIN, HUMAN; FLAVANONE DERIVATIVE;

EID: 84991794158     PISSN: 03445704     EISSN: 14320843     Source Type: Journal    
DOI: 10.1007/s00280-016-3171-y     Document Type: Article
Times cited : (39)

References (34)
  • 1
    • 84902158533 scopus 로고    scopus 로고
    • Global battle against cancer won’t be won with treatment alone effective prevention measures urgently needed to prevent cancer crisis
    • World Health Organization (WHO) (2014) Global battle against cancer won’t be won with treatment alone effective prevention measures urgently needed to prevent cancer crisis. Cent Eur J Publ Health 22(23):28
    • (2014) Cent Eur J Publ Health , vol.22 , Issue.23 , pp. 28
  • 2
    • 84859212951 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • Forner A, Llovet JM, Bruix J (2012) Hepatocellular carcinoma. Lancet 379:1245–1255
    • (2012) Lancet , vol.379 , pp. 1245-1255
    • Forner, A.1    Llovet, J.M.2    Bruix, J.3
  • 3
    • 54449083925 scopus 로고    scopus 로고
    • Molecular targeted therapies in hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BD1cXht1Khu7zP
    • Llovet JM, Bruix J (2008) Molecular targeted therapies in hepatocellular carcinoma. Hepatology 48:1312–1327
    • (2008) Hepatology , vol.48 , pp. 1312-1327
    • Llovet, J.M.1    Bruix, J.2
  • 4
    • 77950612887 scopus 로고    scopus 로고
    • Where are we in the chemoprevention of hepatocellular carcinoma?
    • Lu SC (2010) Where are we in the chemoprevention of hepatocellular carcinoma? Hepatology 51:734–736
    • (2010) Hepatology , vol.51 , pp. 734-736
    • Lu, S.C.1
  • 5
    • 84926672916 scopus 로고    scopus 로고
    • Hepatic artery infusion chemotherapy for advanced hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BC2MXhtVGitbfJ
    • Song MJ (2015) Hepatic artery infusion chemotherapy for advanced hepatocellular carcinoma. World J Gastroenterol 21:3843–3849
    • (2015) World J Gastroenterol , vol.21 , pp. 3843-3849
    • Song, M.J.1
  • 6
    • 78650898208 scopus 로고    scopus 로고
    • Fruit and vegetables and cancer risk
    • Key TJ (2010) Fruit and vegetables and cancer risk. Br J Cancer 104:6–11
    • (2010) Br J Cancer , vol.104 , pp. 6-11
    • Key, T.J.1
  • 7
    • 0037864005 scopus 로고    scopus 로고
    • Natural products for cancer prevention: a global perspective
    • COI: 1:CAS:528:DC%2BD3sXksVehu7Y%3D
    • Reddy L, Odhav B, Bhoola KD (2003) Natural products for cancer prevention: a global perspective. Pharmacol Ther 99:1–13
    • (2003) Pharmacol Ther , vol.99 , pp. 1-13
    • Reddy, L.1    Odhav, B.2    Bhoola, K.D.3
  • 8
    • 79952012742 scopus 로고    scopus 로고
    • Molecular targets of phytochemicals for cancer prevention
    • COI: 1:CAS:528:DC%2BC3MXitVClu7Y%3D
    • Lee KW, Bode AM, Dong Z (2011) Molecular targets of phytochemicals for cancer prevention. Nat Rev Cancer 11:211–218
    • (2011) Nat Rev Cancer , vol.11 , pp. 211-218
    • Lee, K.W.1    Bode, A.M.2    Dong, Z.3
  • 10
    • 84920876906 scopus 로고    scopus 로고
    • Hesperidin ameliorates behavioral impairments and neuropathology of transgenic APP/PS1 mice
    • COI: 1:CAS:528:DC%2BC2MXht1OqsLc%3D
    • Li C, Zug C, Qu H, Schluesener H, Zhang Z (2015) Hesperidin ameliorates behavioral impairments and neuropathology of transgenic APP/PS1 mice. Behav Brain Res 281:32–42
    • (2015) Behav Brain Res , vol.281 , pp. 32-42
    • Li, C.1    Zug, C.2    Qu, H.3    Schluesener, H.4    Zhang, Z.5
  • 11
    • 84928996183 scopus 로고    scopus 로고
    • The antioxidant and antigenotoxic properties of citrus phenolics limonene and naringin
    • COI: 1:CAS:528:DC%2BC2MXnt1ehtrY%3D
    • Bacanli M, Basaran AA, Basaran N (2015) The antioxidant and antigenotoxic properties of citrus phenolics limonene and naringin. Food Chem Toxicol 81:160–170
    • (2015) Food Chem Toxicol , vol.81 , pp. 160-170
    • Bacanli, M.1    Basaran, A.A.2    Basaran, N.3
  • 12
    • 84937622393 scopus 로고    scopus 로고
    • Hesperidin from Citrus seed induces human hepatocellular carcinoma HepG2 cell apoptosis via both mitochondrial and death receptor pathways
    • Banjerdpongchai R, Wudtiwai B, Khaw-On P, Rachakhom W, Duangnil N, Kongtawelert P (2016) Hesperidin from Citrus seed induces human hepatocellular carcinoma HepG2 cell apoptosis via both mitochondrial and death receptor pathways. Tumour Biol 37(1):227–237
    • (2016) Tumour Biol , vol.37 , Issue.1 , pp. 227-237
    • Banjerdpongchai, R.1    Wudtiwai, B.2    Khaw-On, P.3    Rachakhom, W.4    Duangnil, N.5    Kongtawelert, P.6
  • 13
    • 0031870664 scopus 로고    scopus 로고
    • Protective effects of lemon flavonoids on oxidative stress in diabetic rats
    • COI: 1:CAS:528:DyaK1cXkslOqsrg%3D
    • Miyake Y, Yamamoto K, Tsujihara N, Osawa T (1998) Protective effects of lemon flavonoids on oxidative stress in diabetic rats. Lipids 33:689–695
    • (1998) Lipids , vol.33 , pp. 689-695
    • Miyake, Y.1    Yamamoto, K.2    Tsujihara, N.3    Osawa, T.4
  • 14
    • 0037458382 scopus 로고    scopus 로고
    • Lemon flavonoid, eriocitrin, suppresses exercise-induced oxidative damage in rat liver
    • K-i Minato, Miyake Y, Fukumoto S, Yamamoto K, Kato Y, Shimomura Y et al (2003) Lemon flavonoid, eriocitrin, suppresses exercise-induced oxidative damage in rat liver. Life Sci 72:1609–1616
    • (2003) Life Sci , vol.72 , pp. 1609-1616
    • K-i, M.1    Miyake, Y.2    Fukumoto, S.3    Yamamoto, K.4    Kato, Y.5    Shimomura, Y.6
  • 15
    • 84892702942 scopus 로고    scopus 로고
    • Eriocitrin ameliorates diet-induced hepatic steatosis with activation of mitochondrial biogenesis
    • Hiramitsu M, Shimada Y, Kuroyanagi J, Inoue T, Katagiri T, Zang L et al (2014) Eriocitrin ameliorates diet-induced hepatic steatosis with activation of mitochondrial biogenesis. Sci Rep 4:3708
    • (2014) Sci Rep , vol.4 , pp. 3708
    • Hiramitsu, M.1    Shimada, Y.2    Kuroyanagi, J.3    Inoue, T.4    Katagiri, T.5    Zang, L.6
  • 16
    • 84944065622 scopus 로고    scopus 로고
    • Hesperidin inhibits HeLa cell proliferation through apoptosis mediated by endoplasmic reticulum stress pathways and cell cycle arrest
    • Wang Y, Yu H, Zhang J, Gao J, Ge X, Lou G (2015) Hesperidin inhibits HeLa cell proliferation through apoptosis mediated by endoplasmic reticulum stress pathways and cell cycle arrest. BMC Cancer 15:682
    • (2015) BMC Cancer , vol.15 , pp. 682
    • Wang, Y.1    Yu, H.2    Zhang, J.3    Gao, J.4    Ge, X.5    Lou, G.6
  • 17
    • 84995727146 scopus 로고    scopus 로고
    • Maestro, version 10.2
    • LLC, New York
    • Schrödinger Release 2015-2 (2015) Maestro, version 10.2, Schrödinger, LLC, New York
    • (2015) Schrödinger
  • 20
    • 73649145175 scopus 로고    scopus 로고
    • The function of p27 KIP1 during tumor development
    • COI: 1:CAS:528:DC%2BD1MXhsFGqur%2FO
    • Lee J, Kim SS (2009) The function of p27 KIP1 during tumor development. Exp Mol Med 41:765–771
    • (2009) Exp Mol Med , vol.41 , pp. 765-771
    • Lee, J.1    Kim, S.S.2
  • 21
    • 84959461717 scopus 로고    scopus 로고
    • The cell-cycle arrest and apoptotic functions of p53 in tumor initiation and progression
    • Chen J (2016) The cell-cycle arrest and apoptotic functions of p53 in tumor initiation and progression. Cold Spring Harb Perspect Med 6(3):a026104
    • (2016) Cold Spring Harb Perspect Med 6(3) , vol.a026104
    • Chen, J.1
  • 23
    • 84956630703 scopus 로고    scopus 로고
    • Thirty years of BCL-2: translating cell death discoveries into novel cancer therapies
    • COI: 1:CAS:528:DC%2BC28XhslOmsbc%3D
    • Delbridge AR, Grabow S, Strasser A, Vaux DL (2016) Thirty years of BCL-2: translating cell death discoveries into novel cancer therapies. Nat Rev Cancer 16:99–109
    • (2016) Nat Rev Cancer , vol.16 , pp. 99-109
    • Delbridge, A.R.1    Grabow, S.2    Strasser, A.3    Vaux, D.L.4
  • 24
    • 78751482234 scopus 로고    scopus 로고
    • Eriodictyol inhibits RSK2-ATF1 signaling and suppresses EGF-induced neoplastic cell transformation
    • COI: 1:CAS:528:DC%2BC3MXlsFSqsg%3D%3D
    • Liu K, Cho YY, Yao K, Nadas J, Kim DJ, Cho EJ et al (2011) Eriodictyol inhibits RSK2-ATF1 signaling and suppresses EGF-induced neoplastic cell transformation. J Biol Chem 286:2057–2066
    • (2011) J Biol Chem , vol.286 , pp. 2057-2066
    • Liu, K.1    Cho, Y.Y.2    Yao, K.3    Nadas, J.4    Kim, D.J.5    Cho, E.J.6
  • 26
    • 79955406720 scopus 로고    scopus 로고
    • Natural products for cancer chemotherapy
    • Demain AL, Vaishnav P (2011) Natural products for cancer chemotherapy. Microb Biotechnol 4:687–699
    • (2011) Microb Biotechnol , vol.4 , pp. 687-699
    • Demain, A.L.1    Vaishnav, P.2
  • 27
    • 84962121748 scopus 로고    scopus 로고
    • Treating cancer with selective CDK4/6 inhibitors
    • O’Leary B, Finn RS, Turner NC (2016) Treating cancer with selective CDK4/6 inhibitors. Nat Rev Clin Oncol 13(7):417–430
    • (2016) Nat Rev Clin Oncol , vol.13 , Issue.7 , pp. 417-430
    • O’Leary, B.1    Finn, R.S.2    Turner, N.C.3
  • 28
    • 27544470656 scopus 로고    scopus 로고
    • Mammalian cyclin-dependent kinases
    • COI: 1:CAS:528:DC%2BD2MXhtFKhsLvE
    • Malumbres M, Barbacid M (2005) Mammalian cyclin-dependent kinases. Trends Biochem Sci 30:630–641
    • (2005) Trends Biochem Sci , vol.30 , pp. 630-641
    • Malumbres, M.1    Barbacid, M.2
  • 30
    • 84962071033 scopus 로고    scopus 로고
    • Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases
    • Hydbring P, Malumbres M, Sicinski P (2016) Non-canonical functions of cell cycle cyclins and cyclin-dependent kinases. Nat Rev Mol Cell Biol 17(5):280-292
    • (2016) Nat Rev Mol Cell Biol , vol.17 , Issue.5 , pp. 280-292
    • Hydbring, P.1    Malumbres, M.2    Sicinski, P.3
  • 31
    • 67549118622 scopus 로고    scopus 로고
    • Ordering of caspases in cells undergoing apoptosis by the intrinsic pathway
    • COI: 1:CAS:528:DC%2BD1MXnsV2qs7k%3D
    • Inoue S, Browne G, Melino G, Cohen GM (2009) Ordering of caspases in cells undergoing apoptosis by the intrinsic pathway. Cell Death Differ 16:1053–1061
    • (2009) Cell Death Differ , vol.16 , pp. 1053-1061
    • Inoue, S.1    Browne, G.2    Melino, G.3    Cohen, G.M.4
  • 32
    • 10344258041 scopus 로고    scopus 로고
    • Targeting the mitogen-activated protein kinase cascade to treat cancer
    • COI: 1:CAS:528:DC%2BD2cXhtVarsLjO
    • Sebolt-Leopold JS, Herrera R (2004) Targeting the mitogen-activated protein kinase cascade to treat cancer. Nat Rev Cancer 4:937–947
    • (2004) Nat Rev Cancer , vol.4 , pp. 937-947
    • Sebolt-Leopold, J.S.1    Herrera, R.2
  • 33
    • 0037248328 scopus 로고    scopus 로고
    • Cancer prevention—the potential for diet to modulate molecular signalling
    • COI: 1:CAS:528:DC%2BD3sXmsF2n
    • Manson MM (2003) Cancer prevention—the potential for diet to modulate molecular signalling. Trends Mol Med 9:11–18
    • (2003) Trends Mol Med , vol.9 , pp. 11-18
    • Manson, M.M.1
  • 34
    • 84872800836 scopus 로고    scopus 로고
    • Chemopreventive properties of dietary rice bran: current status and future prospects
    • COI: 1:CAS:528:DC%2BC38XhslSktbvO
    • Henderson AJ, Ollila CA, Kumar A, Borresen EC, Raina K, Agarwal R et al (2012) Chemopreventive properties of dietary rice bran: current status and future prospects. Adv Nutr: Int Rev J 3:643–653
    • (2012) Adv Nutr: Int Rev J , vol.3 , pp. 643-653
    • Henderson, A.J.1    Ollila, C.A.2    Kumar, A.3    Borresen, E.C.4    Raina, K.5    Agarwal, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.