Opioid-induced gut microbial disruption and bile dysregulation leads to gut barrier compromise and sustained systemic inflammation

Mucosal Immunology

Volumn 9, Issue 6, 2016, Pages 1418-1428

  Banerjee, S ^a   Sindberg, G ^a   Wang, F ^a   Meng, J ^a   Sharma, U ^a   Zhang, L ^a   Dauer, P ^a   Chen, C ^a   Dalluge, J ^b   Johnson, T ^a   Roy, S ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b University of Minnesota   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA 16S; INTERLEUKIN 10; INTERLEUKIN 17; MORPHINE; MU OPIATE RECEPTOR; NALTREXONE; TOLL LIKE RECEPTOR 2; BILE ACID; CHOLESTEROL; NARCOTIC ANALGESIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL STRAIN; BACTERIAL TRANSLOCATION; BACTEROIDETES; BILE ACID METABOLISM; BILE DUCT DISEASE; CHOLESTEROL METABOLISM; COMMENSAL; CONTROLLED STUDY; DNA SEQUENCE; DYSBIOSIS; FECAL MICROBIOTA TRANSPLANTATION; FIRMICUTES; GRAM POSITIVE BACTERIUM; GUT BARRIER; INFLAMMATION; INTESTINE FLORA; MOUSE; NONHUMAN; PERMEABILITY BARRIER; POPULATION ABUNDANCE; PRIORITY JOURNAL; SPECIES COMPOSITION; ANIMAL; BILE; DRUG EFFECTS; IMMUNE SYSTEM; IMMUNOLOGY; INTESTINE MUCOSA; KNOCKOUT MOUSE; LIVER; METABOLISM; MICROBIOLOGY; MUCOSAL IMMUNITY;

ANALGESICS, OPIOID; ANIMALS; BILE; BILE ACIDS AND SALTS; CHOLESTEROL; DYSBIOSIS; FECAL MICROBIOTA TRANSPLANTATION; GASTROINTESTINAL MICROBIOME; IMMUNE SYSTEM; IMMUNITY, MUCOSAL; INFLAMMATION; INTESTINAL MUCOSA; LIVER; MICE; MICE, KNOCKOUT; MORPHINE; RECEPTORS, OPIOID, MU; TOLL-LIKE RECEPTOR 2;

EID: 84991669737     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2016.9     Document Type: Article

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