Morphine Induces Bacterial Translocation in Mice by Compromising Intestinal Barrier Function in a TLR-Dependent Manner

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Meng, Jingjing ^a   Yu, Haidong ^a   Ma, Jing ^a   Wang, Jinghua ^a   Banerjee, Santanu ^a   Charboneau, Rick ^b   Barke, Roderick A ^b   Roy, Sabita ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MORPHINE; MU OPIATE RECEPTOR; PROTEIN ZO1; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

ARTICLE; BACTERIAL TRANSLOCATION; CELL ISOLATION; COLON; COLONY FORMING UNIT C; CONTROLLED STUDY; ILEUM; INTESTINE; INTESTINE EPITHELIUM; INTESTINE EPITHELIUM CELL; INTESTINE MUCOSA PERMEABILITY; LIVER; MESENTERY LYMPH NODE; MOUSE; NONHUMAN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SEPSIS; SIGNAL TRANSDUCTION; SMALL INTESTINE; TIGHT JUNCTION; UPREGULATION;

ANALGESICS, OPIOID; ANIMALS; AZEPINES; BACTERIAL TRANSLOCATION; BLOTTING, WESTERN; CELL LINE; COLON; EPITHELIUM; ILEUM; INTESTINES; LIVER; LYMPH NODES; MESENTERY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; MORPHINE; MYOSIN-LIGHT-CHAIN KINASE; NAPHTHALENES; RECEPTORS, OPIOID, MU; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIGHT JUNCTIONS; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; ZONULA OCCLUDENS-1 PROTEIN;

ANIMALIA; BACTERIA (MICROORGANISMS); MUS;

EID: 84872527704     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0054040     Document Type: Article

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