A novel mechanism for gut barrier dysfunction by dietary fat: Epithelial disruption by hydrophobic bile acids

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 304, Issue 3, 2013, Pages

  Stenman, Lotta K ^a   Holma, Reetta ^a   Eggert, Ariane ^b   Korpela, Riitta ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

Deoxycholic acid; Inflammation; Intestinal permeability; Lipopolysac charide; Ursodeoxycholic acid

Indexed keywords

BILE ACID; CYCLOOXYGENASE 2; DEOXYCHOLIC ACID; DEXTRAN; FLUORESCEIN ISOTHIOCYANATE; LIPOPOLYSACCHARIDE; URSODEOXYCHOLIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COLON; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG EFFICACY; ENTERITIS; ENTEROPATHY; FAT INTAKE; FECES; FEMALE; GUT BARRIER DYSFUNCTION; HISTOPATHOLOGY; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INTESTINE; INTESTINE EPITHELIUM; INTESTINE FUNCTION; INTESTINE MUCOSA PERMEABILITY; LOW FAT DIET; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; WESTERN BLOTTING;

ANIMALS; BILE ACIDS AND SALTS; BLOTTING, WESTERN; COLON; CYCLOOXYGENASE 2; DEOXYCHOLIC ACID; DEXAMETHASONE; DIETARY FATS; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIUM; GASTRIC MUCOSA; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSA; INTESTINES; JEJUNUM; MALE; MICE; MICE, INBRED C57BL; OCCLUDIN; PERMEABILITY; RATS; RATS, SPRAGUE-DAWLEY; URSODEOXYCHOLIC ACID;

EID: 84873358207     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00267.2012     Document Type: Article

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