Induction of HIV-1 gag specific immune responses by cationic micelles mediated delivery of gag mRNA

Drug Delivery

Volumn 23, Issue 7, 2016, Pages 2596-2607

  Zhao, Mengnan ^a   Li, Man ^a   Zhang, Zhirong ^a   Gong, Tao ^a   Sun, Xun ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Cationic polymers; endosome escape; HIV 1 gag; intracellular cytokine staining; messenger RNA

Indexed keywords

COPOLYMER; CYTOKINE; EPIDERMAL GROWTH FACTOR; HUMAN IMMUNE DEFICIENCY VIRUS 1 GAG MESSENGER RNA; MESSENGER RNA; POLYETHYLENEIMINE STEARIC ACID COPOLYMER; UNCLASSIFIED DRUG; CATION; MICELLE; POLYETHYLENEIMINE-STEARIC ACID; RIBONUCLEASE; STEARIC ACID DERIVATIVE; VACCINE;

ANIMAL EXPERIMENT; ANTIGEN ANTIBODY REACTION; ARTICLE; CELL MATURATION; CELLULAR IMMUNITY; CONTROLLED STUDY; DENDRITIC CELL; FEMALE; GENE DELIVERY SYSTEM; GENETIC CODE; IMMUNE RESPONSE; IMMUNOSTIMULATION; INTRACELLULAR TRANSPORT; MALE; MICELLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA TRANSCRIPTION; RNA TRANSPORT; SPLEEN CELL; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOLOGY; METABOLISM; STRUCTURAL GENE;

ANIMALS; CATIONS; DENDRITIC CELLS; GENES, GAG; HIV-1; HUMANS; MICE; MICE, INBRED BALB C; MICELLES; RIBONUCLEASES; RNA, MESSENGER; STEARIC ACIDS; TRANSFECTION; VACCINES;

EID: 84991660875     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.3109/10717544.2015.1038856     Document Type: Article

References (43)

1. H.M.Aliabadi, B.Landry, R.K.Bahadur,. (2011). Impact of lipid substitution on assembly and delivery of siRNA by cationic polymers. Macromol Biosci 11:662–72
2. A.Alshamsan, A.Haddadi, V.Incani,. (2009). Formulation and delivery of siRNA by oleic acid and stearic acid modified polyethylenimine. Mol Pharm 6:121–33
3. T.Amano, K.Kajiwara, K.Yoshikawa,. (2007). Antitumor effects of vaccination with dendritic cells transfected with modified receptor for hyaluronan-mediated motility mRNA in a mouse glioma model. J Neurosurg 106:638–45
4. T.Bettinger, R.C.Carlisle, M.L.Read,. (2001). Peptide-mediated RNA delivery:a novel approach for enhanced transfection of primary and post-mitotic cells. Nucleic Acid Res 29;3882–91
5. A.Bringmann, S.A.E.Held, A.Heine, P.Brossart. (2010). RNA vaccines in cancer treatment. J Biomed Biotechnol 2010:623687--98
6. Y.W.Cho, J.D.Kim, K.Park. (2003). Polycation gene delivery systems:escape from endosomes to cytosol. J Pharm Pharmacol 55:721–34
7. N.A.Doria-Rose, N.L.Haigwood. (2003). DNA vaccine strategies:candidates for immune modulation and immunization regimens. Methods 31:207–16
8. D.Fischer, T.Bieber, Y.Li,. (1999). A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine:effect of molecular weight on transfection efficiency and cytotoxicity. Pharm Res 16:1273–9
9. M.Fotin-Mleczek, K.M.Duchardt, C.Lorenz,. (2011). Messenger RNA-based vaccines with dual activity induce balanced TLR-7 dependent adaptive immune responses and provide antitumor activity. J Immunother 34:1–15
10. W.T.Godbey, K.K.Wu, A.G.Mikos. (1999). Size matters:molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle. J Biomed Mater Res 45:268–75
11. K.Inaba, M.Inaba, N.Romani,. (1992). Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J Exp Med 176:1693–702
12. K.Kariko, A.Kuo, E.Barnathan. (1999). Overexpression of urokinase receptor in mammalian cells following administration of the in vitro transcribed encoding mRNA. Gene Ther 6:1092–100
13. S.Kreiter, M.Diken, A.Selmi,. (2011). Tumor vaccination using messenger RNA:prospects of a future therapy. Curr Opin Immunol 23:399–406
14. M.Li, Y.H.Jiang, C.Q.Xu,. (2013). Enhanced immune response against HIV-1 induced by a heterologous DNA prime-adenovirus boost vaccination using mannosylated polyethyleneimine as DNA vaccine adjuvant. Int J Nanomed 8:1843–54
15. Z.H.Liu, Z.Y.Zhang, C.R.Zhou, Y.P.Jiao,. (2010). Hydrophobic modifications of cationic polymers for gene delivery. Prog Polym Sci 35:1144–62
16. R.W.Malone, P.L.Felgner, I.M.Verma. (1989). Cationic liposome-mediated RNA transfection. Proc Natl Acad Sci USA 86:6077–81
17. M.Mockey, E.Bourseau, V.Chandrashekhar,. (2007). mRNA-based cancer vaccine:prevention of B16 melanoma progression and metastasis by systemic injection of MART1 mRNA histidylated lipopolyplexes. Cancer Gene Ther 14:802–14
18. S.M.Moghimi, P.Symonds, J.C.Murray,. (2005). A two-stage poly(ethylenimine)-mediated cytotoxicity:Implications for gene transfer/therapy. Mol Ther 11:990–5
19. T.Mosmann. (1983). Rapid colorimetric assay for cellular growth and survival:application to proliferation and cytotoxicity assays. J Immunol Method 65:55–63
20. G.Navarro, J.Pan, V.P.Torchilin. (2015). Micelle-like nanoparticles as carriers for DNA and siRNA. Mol Pharm 12:301--13
21. T.Nishiya, E.Kajita, S.Miwa, A.L.Defranco. (2005). TLR3 and TLR7 are targeted to the same intracellular compartments by distinct regulatory elements. J Biol Chem 280:7–17
22. D.W.Pack, A.S.Hoffman, S.Pun, P.S.Stayton. (2005). Design and development of polymers for gene delivery. Nat Rev Drug Discov 4:581–93
23. R.N.Palumbo, X.Zhong, C.Wang. (2012). Polymer-mediated DNA vaccine delivery via bystander cells requires a proper balance between transfection efficiency and cytotoxicity. J Control Rel 157:86–93
24. F.Perche, T.Benvegnu, M.Berchel,. (2011). Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA. Nanomedicine 7:445–53
25. B.Petsch, M.Schnee, A.B.Vogel,. (2012). Protective efficacy of in vitro synthesized, specific mRNA vaccines against influenza A virus infection. Nat Biotechnol 30:1210--16
26. K.K.L.Phua, S.K.Nair, K.W.Leong,. (2014). Messenger RNA (mRNA) nanoparticle tumour vaccination. Nanoscale 6:7715–29
27. J.Probst, S.Brechtel, B.Scheel,. (2006). Characterization of the ribonuclease activity on the skin surface. Genet Vaccines Ther 4:4--12
28. Y.Qiu, L.Guo, S.Zhang,. (2015). DNA-based vaccination against hepatitis B virus using dissolving microneedle arrays adjuvanted by cationic liposomes and CpG ODN. Drug Deliv 27:1–8
29. S.M.Rittig, M.Haentschel, K.J.Weimer,. (2011). Intradermal vaccinations with rna coding for taa generate CD8(+) and CD4(+) immune responses and induce clinical benefit in vaccinated patients. Mol Ther 19:990–9
30. S.J.Shi, Z.R.Zhong, J.Liu,. (2012). Solid lipid nanoparticles loaded with anti-microrna Oligonucleotides (AMOs) for suppression of microRNA-21 functions in human lung cancer cells. Pharm Res 29:97–109
31. J.Steitz, C.M.Britten, T.Wolfel, T.Tuting. (2006). Effective induction of anti-melanoma immunity following genetic vaccination with synthetic mRNA coding for the fusion protein EGFP.TRP2. Cancer Immunol Immunother 55:246–253
32. X.F.Su, J.Fricke, D.G.Kavanagh, D.J.Irvine. (2011). In vitro and in vivo mRNA delivery using lipid-enveloped ph-responsive polymer nanoparticles. Mol Pharm 8:774–87
33. G.Tavernier, O.Andries, J.Demeester,. (2011). mRNA as gene therapeutic:how to control protein expression. J Control Release 150:238–47
34. S.Uchida, K.Itaka, H.Uchida,. (2013). In vivo messenger RNA introduction into the central nervous system using polyplex nanomicelle. PLoS One 8:e56220
35. B.Weide, J.P.Carralot, A.Reese,. (2008). Results of the first phase I/II clinical vaccination trial with direct injection of mRNA. J Immunother 31:180–8
36. B.Weide, S.Pascolo, B.Scheel,. (2009). Direct injection of protamine-protected mRNA:results of a phase 1/2 vaccination trial in metastatic melanoma patients. J Immunother 32:498–507
37. S.Y.Wong, J.M.Pelet, D.Putnam. (2007). Polymer systems for gene delivery-past, present, and future. Prog Polym Sci 32:99–837
38. A.Yamamoto, M.Kormann, J.Rosenecker, C.Rudolph. (2009). Current prospects for mRNA gene delivery. Eur J Pharm Biopharm 71:484–9
39. H.Yu, L.A.Babiuk, S.V.Littel-Van Den Hurk. (2007). Immunity and protection by adoptive transfer of dendritic cells transfected with hepatitis CNS3/4A mRNA. Vaccine 25:1701–11
40. S.Zarei, J.F.Arrighi, G.Ongaro,. (2003). Efficient induction of CD8 T-associated immune protection by vaccination with mRNA transfected dendritic cells. J Invest Dermatol 121:745–50
41. Q.Zeng, H.Jiang, T.Wang,. (2014). Cationic micelle delivery of Trp2 peptide for efficient lymphatic draining and enhanced cytotoxic T-lymphocyte responses. J Control Release 200:1–12
42. H.M.Zhang, L.W.Zhang, J.Ren,. (2006). Induction of alpha-fetoprotein-specific CD4-and CD8-mediated T-cell response using RNA-transfected dendritic cells. Cell Immunol 239:144–50
43. F.T.Zohra, E.H.Chowdhury, S.Tada,. (2007). Effective delivery with enhanced translational activity synergistically accelerates mRNA-based transfection. Biochem Biophys Res Commun 358:373–8