Solid lipid nanoparticles loaded with anti-microRNA oligonucleotides (AMOs) for suppression of microRNA-21 functions in human lung cancer cells

Pharmaceutical Research

Volumn 29, Issue 1, 2012, Pages 97-109

  Shi, San Jun ^a   Zhong, Zhi Rong ^a   Liu, Jie ^a   Zhang, Zhi Rong ^a   Sun, Xun ^a   Gong, Tao ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Anti miRNA oligonucleotide (AMO); Antisense efficiency; MicroRNA 21; MicroRNA based therapy; Solid lipid nanoparticles

Indexed keywords

ANTI MICRORNA 21 OLIGONUCLEOTIDE; ANTINEOPLASTIC AGENT; CATIONIC LIPID BINDED OLIGONUCLEOTIDE LOADED NANOPARTICLE; COMPLEMENTARY DNA; DIMETHYLDIOCTADECYLAMMONIUM BROMIDE; MICRORNA 21; OLIGONUCLEOTIDE; PHOSPHODIESTERASE; SOLID LIPID NANOPARTICLE; UNCLASSIFIED DRUG; DRUG CARRIER; LIPID; MICRORNA; MIRN21 MICRORNA, HUMAN; NANOPARTICLE;

ANTIPROLIFERATIVE ACTIVITY; ANTISENSE THERAPY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER GENE THERAPY; CANCER INHIBITION; CELL INVASION; CELL MOTILITY; CELL VIABILITY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG STABILITY; GENE EXPRESSION REGULATION; GENE SILENCING; GENE TARGETING; HUMAN; HUMAN CELL; IN VITRO GENE TRANSFER; LUNG CANCER; MIGRATION INHIBITION; MOLECULARLY TARGETED THERAPY; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PHOTON CORRELATION SPECTROSCOPY; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RNA TRANSCRIPTION; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL; ADENOCARCINOMA; CELL PROLIFERATION; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; LUNG TUMOR; TUMOR CELL LINE;

ADENOCARCINOMA; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG CARRIERS; HUMANS; LIPIDS; LUNG NEOPLASMS; MICRORNAS; NANOPARTICLES; OLIGONUCLEOTIDES;

EID: 84859016052     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-011-0514-6     Document Type: Article

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