Transplantation of engineered heart tissue as a biological cardiac assist device for treatment of dilated cardiomyopathy

European Journal of Heart Failure

Volumn 15, Issue 1, 2013, Pages 23-35

  Leontyev, Sergey ^a   Schlegel, Franziska ^a,b,c   Spath, Cathleen ^a,c   Schmiedel, Ronny ^a   Nichtitz, Martin ^a   Boldt, Andreas ^c   Rübsamen, Rudolf ^b   Salameh, Aida ^a   Kostelka, Martin ^a   Mohr, Friedrich Wilhelm ^a   Dhein, Stefan ^a  

^a UNIVERSITY OF LEIPZIG HEART CENTER   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c Translational Centre for Regenerative Medicine   (Germany)

Author keywords

Dilated cardiomyopathy; Engineered heart tissue; Tissue engineering

Indexed keywords

COLLAGEN; MATRIGEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; ECHOCARDIOGRAPHY; ENGINEERED HEART TISSUE; HEART ASSIST DEVICE; HEART MUSCLE CELL; HEART TRANSPLANTATION; HEART VENTRICLE SIZE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TISSUE ENGINEERING;

ANIMALS; ANIMALS, NEWBORN; CARDIOMYOPATHY, DILATED; DISEASE MODELS, ANIMAL; ECHOCARDIOGRAPHY; HEART VENTRICLES; MALE; MYOCYTES, CARDIAC; RATS; RATS, SPRAGUE-DAWLEY; TISSUE ENGINEERING; VENTRICULAR FUNCTION, LEFT;

EID: 84871236387     PISSN: 13889842     EISSN: 18790844     Source Type: Journal    
DOI: 10.1093/eurjhf/hfs200     Document Type: Article

References (35)

1. Taylor DO, Edwards LB, Boucek MM, Trulock EP, Aurora P, Christie J, Dobbels F, Rahmel AO, Keck BM, Hertz MI. Registry of the International Society for Heart and Lung Transplantation: twenty-fourth official adult heart transplant report-J Heart Lung Transplant 2007;26:769-781.
2. Cleland JG, Daubert JC, Erdmann E, Freemantle N, Gras D, Kappenberger L, Tavazzi L, the Cardiac Resynchronization-Heart Failure (CARE-HF) Study Investigators. The effect of cardiac resynchronization on morbidity and mortality in heart failure. N Engl J Med 2005;352:1539-1549.
3. Rogers JG, Aaronson KD, Boyle AJ, Russell SD, Milano CA, Pagani FD, Edwards BS, Park S, John R, Conte JV, Farrar DJ, Slaughter MS, and the HeartMate II Investigators. Continuous flow left ventricular assist device improves functional capacity and quality of life of advanced heart failure patients. J Am Coll Cardiol 2010;55:1826-1834.
4. Hibino N, McGillicuddy E, Matsumura G, Ichihara Y, Naito Y, Breuer C, Shinoka T. Late-term results of tissue-engineered vascular grafts in humans. J Thorac Cardiovasc Surg 2010;139:431-436.
5. Zimmermann WH, Melnychenko I, Wasmeier G, Didie M, Naito H, Nixdorff U, Hess A, Budinsky L, Brune K, Michaelis B, Dhein S, Schwoerer A, Ehmke H, Eschenhagen T. Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts. Nat Med 2006;12:452-458.
6. Watanabe E, Smith DM Jr, Delcarpio JB, Sun J, Smart FW, Van Meter CH Jr, Claycomb WC. Cardiomyocyte transplantation in a porcine myocardial infarction model. Cell Transplant 1998;7:239-246.
7. Reinecke H, Zhang M, Bartosek T, Murry CE. Survival, integration, and differentiation of cardiomyocyte grafts: a study in normal and injured rat hearts. Circulation 1999;100:193-202.
8. Langer R, Vacanti JP. Tissue engineering. Science 1993;260:920-926.
9. Zimmermann WH, Didie M, Wasmeier GH, Nixdorff U, Hess A, Melnychenko I, Boy O, Neuhuber WL,Weyand M, Eschenhagen T. Cardiac grafting of engineered heart tissue in syngenic rats. Circulation 2002;106(12 Suppl 1):I-151-I-157.
10. Dhein S, Garbade J, Rouabah D, Abraham G, Ungemach FR, Schneider K, Ullmann C, Aupperle H, Gummert JF, Mohr FW. Effects of autologous bone marrow stem cell transplantation on beta-adrenoceptor density and electrical activation pattern in a rabbit model of non-ischemic heart failure. J Cardiothorac Surg 2006;1:17-27.
11. Bristow MR, Ginsburg R, Minobe W, Cubicciotti RS, Sageman WS, Lurie K, Billingham ME, Harrison DC, Stinson EB. Decreased catecholamine sensitivity and beta-adrenergic-receptor density in failing human hearts. N Engl J Med 1982; 307:205-211.
12. Weiss JL, Frederiksen JW,Weisfeldt ML. Hemodynamic determinants of the timecourse of fall in canine left ventricular pressure. J Clin Invest 1976;58:751-760.
13. Dhein S, Müller A, Gerwin R, Klaus W. Comparative study on the proarrhythmic effects of some antiarrhythmic agents. Circulation 1993;87:617-630.
14. Durrer D, van derTweel LH. Spread of activation in the left ventricular wall of dog. II. Activation conditions at the epicardial surface. Am Heart J 1954;47:192-203.
15. Hayward R, Hydock DS. Doxorubicin cardiotoxicity in the rat: an in vivo characterization. J Am Assoc Lab Anim Sci 2007;46:20-32.
16. Brodde OE, Michel MC, Zerkowski H-R. Signal transduction mechanisms controlling cardiac contractility and their alterations in chronic heart failure. Cardiovasc Res 1995;30:570-584.
17. Kiuchi K, Shannon RP, Komamura K, Cohen DJ, Bianchi C, Homcy CJ, Vatner SF, Vatner DE. Myocardial beta-adrenergic receptor function during the development of pacing-induced heart failure. J Clin Invest 1993;91:907-914.
18. Engelhardt S, Böhm M, Erdmann E, Lohse MJ. Analysis of beta-adrenergic receptor mRNA levels in human ventricular biopsy specimens by quantitative polymerase chain reactions: progressive reduction of beta 1-adrenergic receptor mRNA in heart failure. J Am Coll Cardiol 1996;27:146-154.
19. Lohse MJ, Engelhardt S, Eschenhagen T. What is the role of b-adrenergic signalling in heart failure? Circ Res 2003;93:896-906.
20. Lohse MJ. G-protein coupled receptor kinases and the heart. Trends Cardiovasc Med 1995;5:63-68.
21. Ungerer M, Böhm M, Elce JS, Erdmann E, Lohse MJ. Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart. Circulation 1993;87:454-463.
22. Ungerer M, Parruti G, Böhm M, Puzicha M, DeBlasi A, Erdmann E, Lohse MJ. Expression of beta-arrestins and beta-adrenergic receptor kinases in the failing human heart. Circ Res 1994;74:206-213.
23. Ping P, Anzai T, Gao M, Hammond HK. Adenylyl cyclase and G-protein receptor kinase expression during development of heart failure. Am J Physiol 1997;273: H707-H717.
24. Rockman HA, Koch WJ, Lefkowitz RJ. Seven-transmembrane-spanning receptors and heart function. Nature 2002;415:206-212.
25. Böhm M, Reiger B, Schwinger RHG, Erdmann E. cAMP concentrations, cAMP dependent protein kinase activity, and phospholamban in non-failing and failing myocardium. Cardiovasc Res 1994;28:1713-1719.
26. Sabbah HN. The cardiac support device and the myosplint: treating heart failure by targeting left ventricular size and shape. Ann Thorac Surg 2003;75 (Suppl): S13-S19.
27. Walsh RG. Design and features of the Acorn CorCap Cardiac Support Device: the concept of passive mechanical diastolic support. Heart Fail Rev 2005;10: 101-107.
28. Tønnessen T, Knudsen CW. Surgical left ventricular remodeling in heart failure. Eur J Heart Fail 2005;7:704-709.
29. Tiburcy M, Didié M, Boy O, Christalla P, Döker S, Naito H, Karikkineth BC, El-Armouche A, Grimm M, Nose M, Eschenhagen T, Zieseniss A, Katschinski DM, Hamdani N, LinkeWA, Yin X, Mayr M, Zimmermann WH. Terminal differentiation, advanced organotypic maturation, and modeling of hypertrophic growth in engineered heart tissue. Circ Res 2011;109:1105-1114.
30. Lesman A, Habib M, Caspi O, Gepstein A, Arbel G, Levenberg S, Gepstein L. Transplantation of a tissue-engineered human vascularized cardiac muscle. Tissue Eng Part A 2010;16:115-125.
31. Caspi O, Lesman A, Basevitch Y, Gepstein A, Arbel G, Habib IH, Gepstein L, Levenberg S. Tissue engineering of vascularized cardiac muscle from human embryonic stem cells. Circ Res 2007;100:263-272.
32. Stevens KR, Kreutziger KL, Dupras SK, Korte FS, Regnier M, Muskheli V, Nourse MB, Bendixen K, Reinicke H, Murry CE. Physiological function and transplantation of scaffold-free and vascularized human cardiac muscle tissue. Proc Natl Acad Sci USA 2009;106:16568-16573
33. Yang ZJ, Ma DC,WangW, Xu SL, Zhang YQ, Chen B, Zhou F, Zhu TB, Wang LS, Jia EZ, Zhang FM, Cao KJ, Xu ZQ, Ma WZ. Neovascularization and cardiomyocytes regeneration in acute myocardial infarction after bone marrow stromal cell transplantation: comparison of infarct-relative and noninfarct-relative arterial approaches in swine. Clin Chim Acta 2007;381:114-118.
34. Dhein S, Hammerrath SB. Aspects of the intercellular communication in aged hearts: effects of the gap junction uncoupler palmitoleic acid. Naunyn Schmiedeberǵs Arch Pharmacol 2001;364:397-408.
35. Kleinman HK, Martin GE. Matrigel: basement membrane matrix with biological activity. Semin Cancer Biol 2005;15:378-386.