Quercetin modulates toll-like receptor-mediated protein kinase signaling pathways in oxLDL-challenged human PBMCs and regulates TLR-activated atherosclerotic inflammation in hypercholesterolemic rats

Molecular and Cellular Biochemistry

Volumn 423, Issue 1-2, 2016, Pages 53-65

  Bhaskar, Shobha ^a   Helen, A ^a  

^a UNIVERSITY OF KERALA   (India)

Author keywords

Atherosclerosis; Cytokines; Inflammation; MAPK; NF B; TLR

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CHOLESTEROL; CLI 095; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDOMETACIN; LIPOXYGENASE; LOW DENSITY LIPOPROTEIN; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; OXIDIZED LOW DENSITY LIPOPROTEIN ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE; PROSTAGLANDIN SYNTHASE; PROTEIN KINASE B; QUERCETIN; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE DISMUTASE; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR AFFECTING AGENT; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; OXIDIZED LOW DENSITY LIPOPROTEIN; TLR4 PROTEIN, HUMAN; TLR4 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC INFLAMMATION; CHOLESTEROL DIET; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; ENZYME INHIBITION; ENZYME MECHANISM; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPERCHOLESTEROLEMIA; IN VIVO STUDY; INFLAMMATION; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; RAT; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; METABOLISM; MONONUCLEAR CELL; PATHOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; ATHEROSCLEROSIS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; HUMANS; HYPERCHOLESTEROLEMIA; INFLAMMATION; LEUKOCYTES, MONONUCLEAR; LIPOPROTEINS, LDL; MAP KINASE SIGNALING SYSTEM; NF-KAPPA B; QUERCETIN; RATS; RATS, SPRAGUE-DAWLEY; TOLL-LIKE RECEPTOR 4;

EID: 84991396191     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-016-2824-9     Document Type: Article

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