-
1
-
-
79952232216
-
Global cancer statistics
-
Jemal, A. et al. Global cancer statistics. CA Cancer J. Clin. 61, 69-90 (2011).
-
(2011)
CA Cancer J. Clin.
, vol.61
, pp. 69-90
-
-
Jemal, A.1
-
2
-
-
74949144690
-
Epidemiology of pancreatic cancer: An overview
-
Raimondi, S. et al. Epidemiology of pancreatic cancer: an overview. Nat. Rev. Gastroenterol. Hepatol. 6, 699-708 (2009).
-
(2009)
Nat. Rev. Gastroenterol. Hepatol.
, vol.6
, pp. 699-708
-
-
Raimondi, S.1
-
3
-
-
84856462406
-
Survival after resection of pancreatic adenocarcinoma: Results from a single institution over three decades
-
Winter, J. M. et al. Survival after resection of pancreatic adenocarcinoma: results from a single institution over three decades. Ann. Surg. Oncol. 19, 169-175 (2012).
-
(2012)
Ann. Surg. Oncol.
, vol.19
, pp. 169-175
-
-
Winter, J.M.1
-
4
-
-
79955921754
-
FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer
-
Conroy, T. et al. FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. N. Engl. J. Med. 364, 1817-1825 (2011).
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 1817-1825
-
-
Conroy, T.1
-
5
-
-
79958776238
-
Metastatic pancreatic cancer: Old drugs, new paradigms
-
Conroy, T. et al. Metastatic pancreatic cancer: old drugs, new paradigms. Curr. Opin. Oncol. 23, 390-395 (2011).
-
(2011)
Curr. Opin. Oncol.
, vol.23
, pp. 390-395
-
-
Conroy, T.1
-
6
-
-
77950931419
-
Matrix metalloproteinases: Regulators of the tumor microenvironment
-
Kessenbrock, K. et al. Matrix metalloproteinases: regulators of the tumor microenvironment. Cell 141, 52-67 (2010).
-
(2010)
Cell
, vol.141
, pp. 52-67
-
-
Kessenbrock, K.1
-
7
-
-
77955887676
-
Gemcitabine plus bevacizumab compared with gemcitabine plus placebo in patients with advanced pancreatic cancer: Phase III trial of the Cancer and Leukemia Group B (CALGB 80303)
-
Kindler, H. L. et al. Gemcitabine plus bevacizumab compared with gemcitabine plus placebo in patients with advanced pancreatic cancer: phase III trial of the Cancer and Leukemia Group B (CALGB 80303). J. Clin. Oncol. 28, 3617-3622 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 3617-3622
-
-
Kindler, H.L.1
-
8
-
-
33644545381
-
Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy
-
DOI 10.1038/nrc1821, PII N1821
-
Overall, C. M. et al. Tumour microenvironment-opinion: validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy. Nat. Rev. Cancer 6, 227-239 (2006). (Pubitemid 43292566)
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.3
, pp. 227-239
-
-
Overall, C.M.1
Kleifeld, O.2
-
9
-
-
60649106195
-
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
-
Paez-Ribes, M. et al. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 15, 220-231 (2009).
-
(2009)
Cancer Cell
, vol.15
, pp. 220-231
-
-
Paez-Ribes, M.1
-
10
-
-
34249933404
-
Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: A phase III trial of the National Cancer Institute of Canada Clinical Trials Group
-
DOI 10.1200/JCO.2006.07.9525
-
Moore, M. J. et al. Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group. J. Clin. Oncol. 25, 1960-1966 (2007). (Pubitemid 46972777)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.15
, pp. 1960-1966
-
-
Moore, M.J.1
Goldstein, D.2
Hamm, J.3
Figer, A.4
Hecht, J.R.5
Gallinger, S.6
Au, H.J.7
Murawa, P.8
Walde, D.9
Wolff, R.A.10
Campos, D.11
Lim, R.12
Ding, K.13
Clark, G.14
Voskoglou-Nomikos, T.15
Ptasynski, M.16
Parulekar, W.17
-
11
-
-
84857126493
-
The impact of the activated stroma on pancreatic ductal adenocarcinoma biology and therapy resistance
-
Erkan, M. et al. The impact of the activated stroma on pancreatic ductal adenocarcinoma biology and therapy resistance. Curr. Mol. Med. 12, 288-303 (2012).
-
(2012)
Curr. Mol. Med.
, vol.12
, pp. 288-303
-
-
Erkan, M.1
-
12
-
-
52149094275
-
The activated stroma index is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma
-
Erkan, M. et al. The activated stroma index is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma. Clin. Gastroenterol. Hepatol. 6, 1155-1161 (2008).
-
(2008)
Clin. Gastroenterol. Hepatol.
, vol.6
, pp. 1155-1161
-
-
Erkan, M.1
-
13
-
-
0023482086
-
Distribution of extracellular matrix proteints in pancreatic ductal adenocarcinoma and its influence on tumor cell proliferation in vitro
-
Mollenhauer, J., Roether, I. & Kern, H. F. Distribution of extracellular matrix proteints in pancreatic ductal adenocarcinoma and its influence on tumor cell proliferation in vitro. Pancreas 2, 14-24 (1987).
-
(1987)
Pancreas
, vol.2
, pp. 14-24
-
-
Mollenhauer, J.1
Roether, I.2
Kern, H.F.3
-
14
-
-
0031842971
-
Periacinar stellate shaped cells in rat pancreas: Identification, isolation, and culture
-
Apte, M. V. et al. Periacinar stellate shaped cells in rat pancreas: identification, isolation, and culture. Gut 43, 128-133 (1998). (Pubitemid 28335501)
-
(1998)
Gut
, vol.43
, Issue.1
, pp. 128-133
-
-
Apte, M.V.1
Haber, P.S.2
Applegate, T.L.3
Norton, I.D.4
McCaughan, G.W.5
Korsten, M.A.6
Pirola, R.C.7
Wilson, J.S.8
-
15
-
-
84863082623
-
Dangerous liaisons: Pancreatic stellate cells and pancreatic cancer cells
-
Apte, M. V. et al. Dangerous liaisons: pancreatic stellate cells and pancreatic cancer cells. J. Gastroenterol. Hepatol. 27 (Suppl. 2), 69-74 (2012).
-
(2012)
J. Gastroenterol. Hepatol.
, vol.27
, Issue.SUPPL. 2
, pp. 69-74
-
-
Apte, M.V.1
-
16
-
-
5444247172
-
Identification, culture, and characterization of pancreatic stellate cells in rats and humans
-
Bachem, M. G. et al. Identification, culture, and characterization of pancreatic stellate cells in rats and humans. Gastroenterology 115, 421-432 (1998).
-
(1998)
Gastroenterology
, vol.115
, pp. 421-432
-
-
Bachem, M.G.1
-
17
-
-
17144404527
-
Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells
-
DOI 10.1053/j.gastro.2004.12.036
-
Bachem, M. G. et al. Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells. Gastroenterology 128, 907-921 (2005). (Pubitemid 40523543)
-
(2005)
Gastroenterology
, vol.128
, Issue.4
, pp. 907-921
-
-
Bachem, M.G.1
Schunemann, M.2
Ramadani, M.3
Siech, M.4
Beger, H.5
Buck, A.6
Zhou, S.7
Schmid-Kotsas, A.8
Adler, G.9
-
18
-
-
84855201311
-
StellaTUM: Current consensus and discussion on pancreatic stellate cell research
-
Erkan, M. et al. StellaTUM: current consensus and discussion on pancreatic stellate cell research. Gut 61, 172-178 (2012).
-
(2012)
Gut
, vol.61
, pp. 172-178
-
-
Erkan, M.1
-
19
-
-
34247236139
-
Periostin Creates a Tumor-Supportive Microenvironment in the Pancreas by Sustaining Fibrogenic Stellate Cell Activity
-
DOI 10.1053/j.gastro.2007.01.031, PII S0016508507001667
-
Erkan, M. et al. Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity. Gastroenterology 132, 1447-1464 (2007). (Pubitemid 46627568)
-
(2007)
Gastroenterology
, vol.132
, Issue.4
, pp. 1447-1464
-
-
Erkan, M.1
Kleeff, J.2
Gorbachevski, A.3
Reiser, C.4
Mitkus, T.5
Esposito, I.6
Giese, T.7
Buchler, M.W.8
Giese, N.A.9
Friess, H.10
-
20
-
-
65949114866
-
Cancer-stellate cell interactions perpetuate the hypoxia-fibrosis cycle in pancreatic ductal adenocarcinoma
-
Erkan, M. et al. Cancer-stellate cell interactions perpetuate the hypoxia-fibrosis cycle in pancreatic ductal adenocarcinoma. Neoplasia 11, 497-508 (2009).
-
(2009)
Neoplasia
, vol.11
, pp. 497-508
-
-
Erkan, M.1
-
21
-
-
38849141696
-
Cancer-associated stromal fibroblasts promote pancreatic tumor progression
-
DOI 10.1158/0008-5472.CAN-07-5714
-
Hwang, R. F. et al. Cancer-associated stromal fibroblasts promote pancreatic tumor progression. Cancer Res. 68, 918-926 (2008). (Pubitemid 351206771)
-
(2008)
Cancer Research
, vol.68
, Issue.3
, pp. 918-926
-
-
Hwang, R.F.1
Moore, T.2
Arumugam, T.3
Ramachandran, V.4
Amos, K.D.5
Rivera, A.6
Ji, B.7
Evans, D.B.8
Logsdon, C.D.9
-
22
-
-
79959659734
-
Tenascin?C enhances pancreatic cancer cell growth and motility and affects cell adhesion through activation of the integrin pathway
-
Paron, I. et al. Tenascin?C enhances pancreatic cancer cell growth and motility and affects cell adhesion through activation of the integrin pathway. PLoS ONE 6, e21684 (2011).
-
(2011)
PLoS ONE
, vol.6
-
-
Paron, I.1
-
23
-
-
42049097658
-
Pancreatic stellate cells: Partners in crime with pancreatic cancer cells
-
DOI 10.1158/0008-5472.CAN-07-2477
-
Vonlaufen, A. et al. Pancreatic stellate cells: partners in crime with pancreatic cancer cells. Cancer Res. 68, 2085-2093 (2008). (Pubitemid 351521780)
-
(2008)
Cancer Research
, vol.68
, Issue.7
, pp. 2085-2093
-
-
Vonlaufen, A.1
Joshi, S.2
Qu, C.3
Phillips, P.A.4
Xu, Z.5
Parker, N.R.6
Toi, C.S.7
Pirola, R.C.8
Wilson, J.S.9
Goldstein, D.10
Apte, M.V.11
-
24
-
-
33845998896
-
The pancreatic stellate cell: A star on the rise in pancreatic diseases
-
DOI 10.1172/JCI30082
-
Omary, M. B., Lugea, A., Lowe, A. W. & Pandol, S. J. The pancreatic stellate cell: a star on the rise in pancreatic diseases. J. Clin. Invest. 117, 50-59 (2007). (Pubitemid 46048449)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.1
, pp. 50-59
-
-
Omary, M.B.1
Lugea, A.2
Lowe, A.W.3
Pandol, S.J.4
-
25
-
-
84863082623
-
Dangerous liaisons: Pancreatic stellate cells and pancreatic cancer cells
-
Apte, M. V. & Wilson, J. S. Dangerous liaisons: pancreatic stellate cells and pancreatic cancer cells. J. Gastroenterol. Hepatol. 27 (Suppl. 2), 69-74 (2012).
-
(2012)
J. Gastroenterol. Hepatol.
, vol.27
, Issue.SUPPL. 2
, pp. 69-74
-
-
Apte, M.V.1
Wilson, J.S.2
-
26
-
-
0028957611
-
Pain and depression in patients with newly diagnosed pancreas cancer
-
Kelsen, D. P. et al. Pain and depression in patients with newly diagnosed pancreas cancer. J. Clin. Oncol. 13, 748-755 (1995).
-
(1995)
J. Clin. Oncol.
, vol.13
, pp. 748-755
-
-
Kelsen, D.P.1
-
27
-
-
11144353646
-
Prospective risk of pancreatic cancer in familial pancreatic cancer kindreds
-
DOI 10.1158/0008-5472.CAN-03-3823
-
Klein, A. P. et al. Prospective risk of pancreatic cancer in familial pancreatic cancer kindreds. Cancer Res. 64, 2634-2638 (2004). (Pubitemid 38523922)
-
(2004)
Cancer Research
, vol.64
, Issue.7
, pp. 2634-2638
-
-
Klein, A.P.1
Brune, K.A.2
Petersen, G.M.3
Goggins, M.4
Tersmette, A.C.5
Offerhaus, G.J.A.6
Griffin, C.7
Cameron, J.L.8
Yeo, C.J.9
Kern, S.10
Hruban, R.H.11
-
28
-
-
0034464147
-
Very high risk of cancer in familial Peutz-Jeghers syndrome
-
Giardiello, F. M. et al. Very high risk of cancer in familial Peutz-Jeghers syndrome. Gastroenterology 119, 1447-1453 (2000). (Pubitemid 32198669)
-
(2000)
Gastroenterology
, vol.119
, Issue.6
, pp. 1447-1453
-
-
Giardiello, F.M.1
Brensinger, J.D.2
Tersmette, A.C.3
Goodman, S.N.4
Petersen, G.M.5
Booker, S.V.6
Cruz-Correa, M.7
Offerhaus, J.A.8
-
29
-
-
0027294719
-
Pancreatitis and the risk of pancreatic cancer
-
DOI 10.1056/NEJM199305203282001
-
Lowenfels, A. B. et al. Pancreatitis and the risk of pancreatic cancer. International Pancreatitis Study Group. N. Engl. J. Med. 328, 1433-1437 (1993). (Pubitemid 23143844)
-
(1993)
New England Journal of Medicine
, vol.328
, Issue.20
, pp. 1433-1437
-
-
Lowenfels, A.B.1
Maisonneuvi, P.2
Cavallini, G.3
Ammann, R.W.4
Lankisch, P.G.5
Andersen, J.R.6
Dimagno, E.P.7
Andren-Sandberg, A.8
Domellof, L.9
Di Francesco, V.10
Pederzoli, P.11
Lohr-Happe, A.12
Krag, E.13
Melton III, I.J.14
Boyle, P.15
Pitchumoni, C.S.16
Wynn, P.S.17
-
30
-
-
84859393143
-
Frequent detection of pancreatic lesions in asymptomatic high-risk individuals
-
Canto, M. I. et al. Frequent detection of pancreatic lesions in asymptomatic high-risk individuals. Gastroenterology 142, 796-804 (2012).
-
(2012)
Gastroenterology
, vol.142
, pp. 796-804
-
-
Canto, M.I.1
-
31
-
-
79955469427
-
Comparison of diffusion-weighted MR imaging and multidetector-row CT in the detection of liver metastases in patients operated for pancreatic cancer
-
Holzapfel, K. et al. Comparison of diffusion-weighted MR imaging and multidetector-row CT in the detection of liver metastases in patients operated for pancreatic cancer. Abdom. Imaging 36, 179-184 (2011).
-
(2011)
Abdom. Imaging
, vol.36
, pp. 179-184
-
-
Holzapfel, K.1
-
32
-
-
84858002179
-
Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: A comparative study in transgenic mice and human tissues
-
Aichler, M. et al. Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: a comparative study in transgenic mice and human tissues. J. Pathol. 226, 723-734 (2011).
-
(2011)
J. Pathol.
, vol.226
, pp. 723-734
-
-
Aichler, M.1
-
33
-
-
33748056792
-
Multifocal neoplastic precursor lesions associated with lobular atrophy of the pancreas in patients having a strong family history of pancreatic cancer
-
DOI pas.0000213265.84725.0b, PII 0000047820060900000001
-
Brune, K. et al. Multifocal neoplastic precursor lesions associated with lobular atrophy of the pancreas in patients having a strong family history of pancreatic cancer. Am. J. Surg. Pathol. 30, 1067-1076 (2006). (Pubitemid 44299338)
-
(2006)
American Journal of Surgical Pathology
, vol.30
, Issue.9
, pp. 1067-1076
-
-
Brune, K.1
Abe, T.2
Canto, M.3
O'Malley, L.4
Klein, A.P.5
Maitra, A.6
Volkan Adsay, N.7
Fishman, E.K.8
Cameron, J.L.9
Yeo, C.J.10
Kern, S.E.11
Goggins, M.12
Hruban, R.H.13
-
34
-
-
84860112131
-
What we have learned about pancreatic cancer from mouse models
-
Pérez-Mancera, P. A. et al. What we have learned about pancreatic cancer from mouse models. Gastroenterology 142, 1079-1092 (2012).
-
(2012)
Gastroenterology
, vol.142
, pp. 1079-1092
-
-
Pérez-Mancera, P.A.1
-
35
-
-
49849101934
-
Pancreatic ductal adenocarcinoma: Cellular origin, signaling pathways and stroma contribution
-
Hernandez-Munoz, I. et al. Pancreatic ductal adenocarcinoma: cellular origin, signaling pathways and stroma contribution. Pancreatology 8, 462-469 (2008).
-
(2008)
Pancreatology
, vol.8
, pp. 462-469
-
-
Hernandez-Munoz, I.1
-
36
-
-
0017797689
-
Islet cells as a component of pancreatic ductal neoplasms. I. Experimental study: Ductular cells, including islet cell precursors, as primary progenitor cells of tumors
-
Pour, P. Islet cells as a component of pancreatic ductal neoplasms. I. Experimental study: ductular cells, including islet cell precursors, as primary progenitor cells of tumors. Am. J. Pathol. 90, 295-316 (1978).
-
(1978)
Am. J. Pathol.
, vol.90
, pp. 295-316
-
-
Pour, P.1
-
37
-
-
77956928318
-
AZGP1 is a tumor suppressor in pancreatic cancer inducing mesenchymal?to?epithelial transdifferentiation by inhibiting TGFmediated ERK signaling
-
Kong, B. et al. AZGP1 is a tumor suppressor in pancreatic cancer inducing mesenchymal?to?epithelial transdifferentiation by inhibiting TGFmediated ERK signaling. Oncogene 29, 5146-5158 (2010).
-
(2010)
Oncogene
, vol.29
, pp. 5146-5158
-
-
Kong, B.1
-
38
-
-
69949185673
-
Update on pancreatic intraepithelial neoplasia
-
Hruban, R. H. et al. Update on pancreatic intraepithelial neoplasia. Int. J. Clin. Exp. Pathol. 1, 306-316 (2008).
-
(2008)
Int. J. Clin. Exp. Pathol.
, vol.1
, pp. 306-316
-
-
Hruban, R.H.1
-
39
-
-
79952423651
-
Cystic precursors to invasive pancreatic cancer
-
Matthaei, H. et al. Cystic precursors to invasive pancreatic cancer. Nat. Rev. Gastroenterol. Hepatol. 8, 141-150 (2011).
-
(2011)
Nat. Rev. Gastroenterol. Hepatol.
, vol.8
, pp. 141-150
-
-
Matthaei, H.1
-
40
-
-
11144356549
-
Main-duct intraductal papillary mucinous neoplasms of the pancreas: Clinical predictors of malignancy and long-term survival following resection
-
Salvia, R. et al. Main-duct intraductal papillary mucinous neoplasms of the pancreas: clinical predictors of malignancy and long-term survival following resection. Ann. Surg. 239, 678-685 (2004).
-
(2004)
Ann. Surg.
, vol.239
, pp. 678-685
-
-
Salvia, R.1
-
41
-
-
2442717796
-
Intraductal papillary mucinous neoplasms of the pancreas: An updated experience
-
Sohn, T. A. et al. Intraductal papillary mucinous neoplasms of the pancreas: an updated experience. Ann. Surg. 239, 788-797 (2004).
-
(2004)
Ann. Surg.
, vol.239
, pp. 788-797
-
-
Sohn, T.A.1
-
42
-
-
0033803651
-
The prognosis of intraductal papillary mucinous tumors of the pancreas
-
Yamao, K. et al. The prognosis of intraductal papillary mucinous tumors of the pancreas. Hepatogastroenterology 47, 1129-1134 (2000).
-
(2000)
Hepatogastroenterology
, vol.47
, pp. 1129-1134
-
-
Yamao, K.1
-
43
-
-
0036838464
-
Prognosis of malignant intraductal papillary mucinous tumours of the pancreas after surgical resection. Comparison with pancreatic ductal adenocarcinoma
-
DOI 10.1136/gut.51.5.717
-
Maire, F. et al. Prognosis of malignant intraductal papillary mucinous tumours of the pancreas after surgical resection. Comparison with pancreatic ductal adenocarcinoma. Gut 51, 717-722 (2002). (Pubitemid 35216862)
-
(2002)
Gut
, vol.51
, Issue.5
, pp. 717-722
-
-
Maire, F.1
Hammel, P.2
Terris, B.3
Paye, F.4
Scoazec, J.-Y.5
Cellier, C.6
Barthet, M.7
O'Toole, D.8
Rufat, P.9
Partensky, C.10
Cuillerier, E.11
Levy, P.12
Belghiti, J.13
Ruszniewski, P.14
-
44
-
-
24944572259
-
Pten constrains centroacinar cell expansion and malignant transformation in the pancreas
-
DOI 10.1016/j.ccr.2005.07.015, PII S1535610805002369
-
Stanger, B. Z. et al. Pten constrains centroacinar cell expansion and malignant transformation in the pancreas. Cancer Cell 8, 185-195 (2005). (Pubitemid 41317590)
-
(2005)
Cancer Cell
, vol.8
, Issue.3
, pp. 185-195
-
-
Stanger, B.Z.1
Stiles, B.2
Lauwers, G.Y.3
Bardeesy, N.4
Mendoza, M.5
Wang, Y.6
Greenwood, A.7
Cheng, K.-H.8
McLaughlin, M.9
Brown, D.10
DePinho, R.A.11
Wu, H.12
Melton, D.A.13
Dor, Y.14
-
45
-
-
0035252589
-
A murine tumor progression model for pancreatic cancer recapitulating the genetic alterations of the human disease
-
DOI 10.1101/gad.184701
-
Wagner, M. et al. A murine tumor progression model for pancreatic cancer recapitulating the genetic alterations of the human disease. Genes Dev. 15, 286-293 (2001). (Pubitemid 32155144)
-
(2001)
Genes and Development
, vol.15
, Issue.3
, pp. 286-293
-
-
Wagner, M.1
Greten, F.R.2
Weber, C.K.3
Koschnick, S.4
Mattfeldt, T.5
Deppert, W.6
Kern, H.7
Adler, G.8
Schmid, R.M.9
-
46
-
-
77957726424
-
Tumor microenvironment and progression of pancreatic cancer
-
Erkan, M. et al. Tumor microenvironment and progression of pancreatic cancer. Exp. Oncol. 32, 128-131 (2010).
-
(2010)
Exp. Oncol.
, vol.32
, pp. 128-131
-
-
Erkan, M.1
-
47
-
-
79959665788
-
In vivo diagnosis of murine pancreatic intraepithelial neoplasia and early-stage pancreatic cancer by molecular imaging
-
Eser, S. et al. In vivo diagnosis of murine pancreatic intraepithelial neoplasia and early-stage pancreatic cancer by molecular imaging. Proc. Natl Acad. Sci. USA 108, 9945-9950 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 9945-9950
-
-
Eser, S.1
-
48
-
-
33847419143
-
Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K-Ras oncogenes in adult mice
-
DOI 10.1016/j.ccr.2007.01.012, PII S153561080700027X
-
Guerra, C. et al. Chronic pancreatitis is essential for induction of pancreatic ductal adenocarcinoma by K?Ras oncogenes in adult mice. Cancer Cell 11, 291-302 (2007). (Pubitemid 46349841)
-
(2007)
Cancer Cell
, vol.11
, Issue.3
, pp. 291-302
-
-
Guerra, C.1
Schuhmacher, A.J.2
Canamero, M.3
Grippo, P.J.4
Verdaguer, L.5
Perez-Gallego, L.6
Dubus, P.7
Sandgren, E.P.8
Barbacid, M.9
-
49
-
-
0034161922
-
Irradiated mammary gland stroma promotes the expression of tumorigenic potential by unirradiated epithelial cells
-
Barcellos-Hoff, M. H. et al. Irradiated mammary gland stroma promotes the expression of tumorigenic potential by unirradiated epithelial cells. Cancer Res. 60, 1254-1260 (2000). (Pubitemid 30151992)
-
(2000)
Cancer Research
, vol.60
, Issue.5
, pp. 1254-1260
-
-
Barcellos-Hoff, M.H.1
Ravani, S.A.2
-
50
-
-
77954861244
-
Matrix metalloproteinase-induced epithelial-mesenchymal transition in breast cancer
-
Radisky, E. S. et al. Matrix metalloproteinase-induced epithelial-mesenchymal transition in breast cancer. J. Mammary Gland Biol. Neoplasia 15, 201-212 (2010).
-
(2010)
J. Mammary Gland Biol. Neoplasia
, vol.15
, pp. 201-212
-
-
Radisky, E.S.1
-
51
-
-
0033597726
-
The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis
-
DOI 10.1016/S0092-8674(00)81009-0
-
Sternlicht, M. D. et al. The stromal proteinase MMP3/stromelysin?1 promotes mammary carcinogenesis. Cell 98, 137-146 (1999). (Pubitemid 29344902)
-
(1999)
Cell
, vol.98
, Issue.2
, pp. 137-146
-
-
Sternlicht, M.D.1
Lochtest, A.2
Sympson, C.J.3
Huey, B.4
Rougier, J.-P.5
Gray, J.W.6
Pinkel, D.7
Bissell, M.J.8
Werb, Z.9
-
52
-
-
66449129565
-
Interplay of tumor microenvironment cell types with parenchymal cells in pancreatic cancer development and therapeutic implications
-
Guturu, P. et al. Interplay of tumor microenvironment cell types with parenchymal cells in pancreatic cancer development and therapeutic implications. J. Gastrointest. Cancer 40, 1-9 (2009).
-
(2009)
J. Gastrointest. Cancer
, vol.40
, pp. 1-9
-
-
Guturu, P.1
-
53
-
-
63849290925
-
Fibrinogen induces cytokine and collagen production in pancreatic stellate cells
-
Masamune, A. et al. Fibrinogen induces cytokine and collagen production in pancreatic stellate cells. Gut 58, 550-559 (2009).
-
(2009)
Gut
, vol.58
, pp. 550-559
-
-
Masamune, A.1
-
54
-
-
71849112654
-
Desmoplasia of pancreatic ductal adenocarcinoma
-
Pandol, S. et al. Desmoplasia of pancreatic ductal adenocarcinoma. Clin. Gastroenterol. Hepatol. 7 (11 Suppl.), S44-S47 (2009).
-
(2009)
Clin. Gastroenterol. Hepatol.
, vol.7
, Issue.11 SUPPL.
-
-
Pandol, S.1
-
55
-
-
42049095085
-
Matrix metalloproteinase-induced fibrosis and malignancy in breast and lung
-
DOI 10.1513/pats.200711-166DR
-
Radisky, D. C. et al. Matrix metalloproteinase-induced fibrosis and malignancy in breast and lung. Proc. Am. Thorac. Soc. 5, 316-322 (2008). (Pubitemid 351520677)
-
(2008)
Proceedings of the American Thoracic Society
, vol.5
, Issue.3
, pp. 316-322
-
-
Radisky, D.C.1
Przybylo, J.A.2
-
56
-
-
77951145570
-
Organ?, inflammation- and cancer specific transcriptional fingerprints of pancreatic and hepatic stellate cells
-
Erkan, M. et al. Organ?, inflammation- and cancer specific transcriptional fingerprints of pancreatic and hepatic stellate cells. Mol. Cancer 9, 88 (2010).
-
(2010)
Mol. Cancer
, vol.9
, pp. 88
-
-
Erkan, M.1
-
57
-
-
55249103738
-
Activation of Wnt signalling in stroma from pancreatic cancer identified by gene expression profiling
-
Pilarsky, C. et al. Activation of Wnt signalling in stroma from pancreatic cancer identified by gene expression profiling. J. Cell. Mol. Med. 12, 2823-2835 (2008).
-
(2008)
J. Cell. Mol. Med.
, vol.12
, pp. 2823-2835
-
-
Pilarsky, C.1
-
58
-
-
56449092747
-
Hypoxia stimulates pancreatic stellate cells to induce fibrosis and angiogenesis in pancreatic cancer
-
Masamune, A. et al. Hypoxia stimulates pancreatic stellate cells to induce fibrosis and angiogenesis in pancreatic cancer. Am. J. Physiol. Gastrointest. Liver Physiol. 295, G709-G717 (2008).
-
(2008)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.295
-
-
Masamune, A.1
-
59
-
-
84871157346
-
Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer
-
Jacobetz, M. A. et al. Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer. Gut http:// dx.doi.org/10.1136/ gutjnl-2012-302529.
-
Gut
-
-
Jacobetz, M.A.1
-
60
-
-
79955589113
-
Pigment epithelium-derived factor associates with neuropathy and fibrosis in pancreatic cancer
-
Samkharadze, T. et al. Pigment epithelium-derived factor associates with neuropathy and fibrosis in pancreatic cancer. Am. J. Gastroenterol. 106, 968-980 (2011).
-
(2011)
Am. J. Gastroenterol.
, vol.106
, pp. 968-980
-
-
Samkharadze, T.1
-
61
-
-
84862514391
-
Comparison of 3'?deoxy?3'?[(18)F]fluorothymidine positron emission tomography (FLT PET) and FDG PET/CT for the detection and characterization of pancreatic tumours
-
Herrmann, K. et al. Comparison of 3'?deoxy?3'?[(18)F]fluorothymidine positron emission tomography (FLT PET) and FDG PET/CT for the detection and characterization of pancreatic tumours. Eur. J. Nucl. Med. Mol. Imaging 39, 846-851 (2012).
-
(2012)
Eur. J. Nucl. Med. Mol. Imaging
, vol.39
, pp. 846-851
-
-
Herrmann, K.1
-
62
-
-
79251492724
-
Plectin?1 as a novel biomarker for pancreatic cancer
-
Bausch, D. et al. Plectin?1 as a novel biomarker for pancreatic cancer. Clin. Cancer Res. 17, 302-309 (2011).
-
(2011)
Clin. Cancer Res.
, vol.17
, pp. 302-309
-
-
Bausch, D.1
-
63
-
-
84865008800
-
Detection of pancreatic cancer tumours and precursor lesions by cathepsin e activity in mouse models
-
Cruz-Monserrate, Z. et al. Detection of pancreatic cancer tumours and precursor lesions by cathepsin E activity in mouse models. Gut http://dx.doi.org/10.1136/gutjnl-2011-300544.
-
Gut
-
-
Cruz-Monserrate, Z.1
-
64
-
-
34547835136
-
111In-labelled bombesin analogues for molecular imaging of prostate tumours
-
DOI 10.1007/s00259-006-0356-3
-
de Visser, M. et al. Novel 111In-labelled bombesin analogues for molecular imaging of prostate tumours. Eur. J. Nucl. Med. Mol. Imaging 34, 1228-1238 (2007). (Pubitemid 47296771)
-
(2007)
European Journal of Nuclear Medicine and Molecular Imaging
, vol.34
, Issue.8
, pp. 1228-1238
-
-
De Visser, M.1
Bernard, H.F.2
Erion, J.L.3
Schmidt, M.A.4
Srinivasan, A.5
Waser, B.6
Reubi, J.C.7
Krenning, E.P.8
De Jong, M.9
-
65
-
-
80052475863
-
Assessment of neovascular permeability in a pancreatic tumor model using dynamic contrast-enhanced (DCE) MRI with contrast agents of different molecular weights
-
Delrue, L. J. et al. Assessment of neovascular permeability in a pancreatic tumor model using dynamic contrast-enhanced (DCE) MRI with contrast agents of different molecular weights. MAGMA 24, 225-232 (2011).
-
(2011)
MAGMA
, vol.24
, pp. 225-232
-
-
Delrue, L.J.1
-
66
-
-
70349974835
-
MALDI-ion mobility separation-mass spectrometry imaging of glucose-regulated protein 78 kDa (Grp78) in human formalin-fixed, paraffin-embedded pancreatic adenocarcinoma tissue sections
-
Djidja, M. C. et al. MALDI-ion mobility separation-mass spectrometry imaging of glucose-regulated protein 78 kDa (Grp78) in human formalin-fixed, paraffin-embedded pancreatic adenocarcinoma tissue sections. J. Proteome Res. 8, 4876-4884 (2009).
-
(2009)
J. Proteome Res.
, vol.8
, pp. 4876-4884
-
-
Djidja, M.C.1
-
67
-
-
50249176480
-
Near infrared fluorescence-based bacteriophage particles for ratiometric pH imaging
-
Hilderbrand, S. A. et al. Near infrared fluorescence-based bacteriophage particles for ratiometric pH imaging. Bioconjug. Chem. 19, 1635-1639 (2008).
-
(2008)
Bioconjug. Chem.
, vol.19
, pp. 1635-1639
-
-
Hilderbrand, S.A.1
-
68
-
-
43249086840
-
Targeted nanoparticles for imaging incipient pancreatic ductal adenocarcinoma
-
Kelly, K. A. et al. Targeted nanoparticles for imaging incipient pancreatic ductal adenocarcinoma. PLoS Med. 5, e85 (2008).
-
(2008)
PLoS Med.
, vol.5
-
-
Kelly, K.A.1
-
69
-
-
80054097776
-
An RNA aptamer that specifically binds pancreatic adenocarcinoma up-regulated factor inhibits migration and growth of pancreatic cancer cells
-
Kim, Y. H. et al. An RNA aptamer that specifically binds pancreatic adenocarcinoma up-regulated factor inhibits migration and growth of pancreatic cancer cells. Cancer Lett. 313, 76-83 (2011).
-
(2011)
Cancer Lett.
, vol.313
, pp. 76-83
-
-
Kim, Y.H.1
-
70
-
-
84856513069
-
Pharmacokinetically stabilized cystine knot peptides that bind alpha?v?beta?6 integrin with single-digit nanomolar affinities for detection of pancreatic cancer
-
Kimura, R. H. et al. Pharmacokinetically stabilized cystine knot peptides that bind alpha?v?beta?6 integrin with single-digit nanomolar affinities for detection of pancreatic cancer. Clin. Cancer Res. 18, 839-849 (2012).
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 839-849
-
-
Kimura, R.H.1
-
71
-
-
77954214387
-
Identification of novel pancreatic adenocarcinoma cell-surface targets by gene expression profiling and tissue microarray
-
Morse, D. L. et al. Identification of novel pancreatic adenocarcinoma cell-surface targets by gene expression profiling and tissue microarray. Biochem. Pharmacol. 80, 748-754 (2010).
-
(2010)
Biochem. Pharmacol.
, vol.80
, pp. 748-754
-
-
Morse, D.L.1
-
72
-
-
79251557485
-
In vivo imaging of pancreatic tumours and liver metastases using 7 Tesla MRI in a murine orthotopic pancreatic cancer model and a liver metastases model
-
Partecke, I. L. et al. In vivo imaging of pancreatic tumours and liver metastases using 7 Tesla MRI in a murine orthotopic pancreatic cancer model and a liver metastases model. BMC Cancer 11, 40 (2011).
-
(2011)
BMC Cancer
, vol.11
, pp. 40
-
-
Partecke, I.L.1
-
73
-
-
79958122939
-
Aptamers: Potential applications to pancreatic cancer therapy
-
Rialon, K. L. et al. Aptamers: potential applications to pancreatic cancer therapy. Anticancer Agents Med. Chem. 11, 434-441 (2011).
-
(2011)
Anticancer Agents Med. Chem.
, vol.11
, pp. 434-441
-
-
Rialon, K.L.1
-
74
-
-
67349227159
-
Molecular imaging of pancreatic cancer in an animal model using targeted multifunctional nanoparticles
-
Yang, L. et al. Molecular imaging of pancreatic cancer in an animal model using targeted multifunctional nanoparticles. Gastroenterology 136, 1514-1525.e2 (2009).
-
(2009)
Gastroenterology
, vol.136
-
-
Yang, L.1
-
75
-
-
80051596401
-
Single-domain antibody bioconjugated near-IR quantum dots for targeted cellular imaging of pancreatic cancer
-
Zaman, M. B. et al. Single-domain antibody bioconjugated near-IR quantum dots for targeted cellular imaging of pancreatic cancer. J. Nanosci. Nanotechnol. 11, 3757-3763 (2011).
-
(2011)
J. Nanosci. Nanotechnol.
, vol.11
, pp. 3757-3763
-
-
Zaman, M.B.1
-
76
-
-
79954875973
-
DCE-MRI using small-molecular and albumin-binding contrast agents in experimental carcinomas with different stromal content
-
Farace, P. et al. DCE-MRI using small-molecular and albumin-binding contrast agents in experimental carcinomas with different stromal content. Eur. J. Radiol. 78, 52-59 (2011).
-
(2011)
Eur. J. Radiol.
, vol.78
, pp. 52-59
-
-
Farace, P.1
-
77
-
-
48749102426
-
Periostin deposition in the stroma of invasive and intraductal neoplasms of the pancreas
-
Fukushima, N. et al. Periostin deposition in the stroma of invasive and intraductal neoplasms of the pancreas. Mod. Pathol. 21, 1044-1053 (2008).
-
(2008)
Mod. Pathol.
, vol.21
, pp. 1044-1053
-
-
Fukushima, N.1
-
78
-
-
78049300013
-
Pancreatic stellate cells produce acetylcholine and may play a role in pancreatic exocrine secretion
-
Phillips, P. A. et al. Pancreatic stellate cells produce acetylcholine and may play a role in pancreatic exocrine secretion. Proc. Natl Acad. Sci. USA 107, 17397-17402 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 17397-17402
-
-
Phillips, P.A.1
-
79
-
-
38349111690
-
NADPH oxidase plays a crucial role in the activation of pancreatic stellate cells
-
Masamune, A. et al. NADPH oxidase plays a crucial role in the activation of pancreatic stellate cells. Am. J. Physiol. Gastrointest. Liver Physiol. 294, G99-G108 (2008).
-
(2008)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.294
-
-
Masamune, A.1
-
80
-
-
34247399552
-
Expression of extracellular matrix metalloproteinase inducer (EMMPRIN/CD147) in pancreatic neoplasm and pancreatic stellate cells
-
Zhang, W. et al. Expression of extracellular matrix metalloproteinase inducer (EMMPRIN/CD147) in pancreatic neoplasm and pancreatic stellate cells. Cancer Biol. Ther. 6, 218-227 (2007). (Pubitemid 46641626)
-
(2007)
Cancer Biology and Therapy
, vol.6
, Issue.2
, pp. 218-227
-
-
Zhang, W.1
Erkan, M.2
Abiatari, I.3
Giese, N.A.4
Felix, K.5
Kayed, H.6
Buchler, M.W.7
Friess, H.8
Kleeff, J.9
-
81
-
-
57449083295
-
Pancreatic islet and stellate cells are the main sources of endocrine gland-derived vascular endothelial growth factor/prokineticin?1 in pancreatic cancer
-
Jiang, X. et al. Pancreatic islet and stellate cells are the main sources of endocrine gland-derived vascular endothelial growth factor/prokineticin?1 in pancreatic cancer. Pancreatology 9, 165-172 (2009).
-
(2009)
Pancreatology
, vol.9
, pp. 165-172
-
-
Jiang, X.1
-
82
-
-
46949105850
-
Pancreatic stellate cells express Toll-like receptors
-
DOI 10.1007/s00535-008-2162-0
-
Masamune, A. et al. Pancreatic stellate cells express Toll-like receptors. J. Gastroenterol. 43, 352-362 (2008). (Pubitemid 351958899)
-
(2008)
Journal of Gastroenterology
, vol.43
, Issue.5
, pp. 352-362
-
-
Masamune, A.1
Kikuta, K.2
Watanabe, T.3
Satoh, K.4
Satoh, A.5
Shimosegawa, T.6
-
83
-
-
67149143399
-
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
-
Olive, K. P. et al. Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer. Science 324, 1457-1461 (2009).
-
(2009)
Science
, vol.324
, pp. 1457-1461
-
-
Olive, K.P.1
-
84
-
-
78149315330
-
Role of pancreatic stellate cells in pancreatic cancer metastasis
-
Xu, Z. et al. Role of pancreatic stellate cells in pancreatic cancer metastasis. Am. J. Pathol. 177, 2585-2596 (2010).
-
(2010)
Am. J. Pathol.
, vol.177
, pp. 2585-2596
-
-
Xu, Z.1
-
85
-
-
2642547301
-
Inflammatory cells contribute to the generation of an angiogenic phenotype in pancreatic ductal adenocarcinoma
-
DOI 10.1136/jcp.2003.014498
-
Esposito, I. et al. Inflammatory cells contribute to the generation of an angiogenic phenotype in pancreatic ductal adenocarcinoma. J. Clin. Pathol. 57, 630-636 (2004). (Pubitemid 38725766)
-
(2004)
Journal of Clinical Pathology
, vol.57
, Issue.6
, pp. 630-636
-
-
Esposito, I.1
Menicagli, M.2
Funel, N.3
Bergmann, F.4
Boggi, U.5
Mosca, F.6
Bevilacqua, G.7
Campani, D.8
-
86
-
-
32944463899
-
Angiogenesis
-
DOI 10.1146/annurev.med.57.121304.131306
-
Folkman, J. Angiogenesis. Annu. Rev. Med. 57, 1-18 (2006). (Pubitemid 43261975)
-
(2006)
Annual Review of Medicine
, vol.57
, pp. 1-18
-
-
Folkman, J.1
-
87
-
-
58149173406
-
Hypoxia-inducible proto-oncogene Pim?1 is a prognostic marker in pancreatic ductal adenocarcinoma
-
Reiser-Erkan, C. et al. Hypoxia-inducible proto-oncogene Pim?1 is a prognostic marker in pancreatic ductal adenocarcinoma. Cancer Biol. Ther. 7, 1352-1359 (2008).
-
(2008)
Cancer Biol. Ther.
, vol.7
, pp. 1352-1359
-
-
Reiser-Erkan, C.1
-
88
-
-
39049083918
-
Mononuclear cells modulate the activity of pancreatic stellate cells which in turn promote fibrosis and inflammation in chronic pancreatitis
-
Michalski, C. W. et al. Mononuclear cells modulate the activity of pancreatic stellate cells which in turn promote fibrosis and inflammation in chronic pancreatitis. J. Transl. Med. 5, 63 (2007).
-
(2007)
J. Transl. Med.
, vol.5
, pp. 63
-
-
Michalski, C.W.1
-
89
-
-
47049123545
-
Cannabinoids reduce markers of inflammation and fibrosis in pancreatic stellate cells
-
Michalski, C. W. et al. Cannabinoids reduce markers of inflammation and fibrosis in pancreatic stellate cells. PLoS ONE 3, e1701 (2008).
-
(2008)
PLoS ONE
, vol.3
-
-
Michalski, C.W.1
-
90
-
-
49749145668
-
Senescence of activated stellate cells limits liver fibrosis
-
Krizhanovsky, V. et al. Senescence of activated stellate cells limits liver fibrosis. Cell 134, 657-667 (2008).
-
(2008)
Cell
, vol.134
, pp. 657-667
-
-
Krizhanovsky, V.1
-
91
-
-
83355169753
-
Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: A phase I/II trial
-
Von Hoff, D. D. et al. Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: a phase I/II trial. J. Clin. Oncol. 29, 4548-4554 (2011).
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 4548-4554
-
-
Von Hoff, D.D.1
-
92
-
-
0016256329
-
The renin-angiotensin system (second of two parts)
-
Oparil, S. et al. The renin-angiotensin system (second of two parts). N. Engl. J. Med. 291, 446-457 (1974).
-
(1974)
N. Engl. J. Med.
, vol.291
, pp. 446-457
-
-
Oparil, S.1
-
93
-
-
0016261414
-
The renin-angiotensin system (first of two parts)
-
Oparil, S. et al. The renin-angiotensin system (first of two parts). N. Engl. J. Med. 291, 389-401 (1974).
-
(1974)
N. Engl. J. Med.
, vol.291
, pp. 389-401
-
-
Oparil, S.1
-
94
-
-
0017413556
-
Renin angiotensin system: Biochemistry and mechanisms of action
-
Peach, M. J. Renin-angiotensin system: biochemistry and mechanisms of action. Physiol. Rev. 57, 313-370 (1977). (Pubitemid 8097628)
-
(1977)
Physiological Reviews
, vol.57
, Issue.2
, pp. 313-370
-
-
Peach, M.J.1
-
95
-
-
33745845825
-
Physiology of local renin-angiotensin systems
-
DOI 10.1152/physrev.00036.2005
-
Paul, M. et al. Physiology of local renin-angiotensin systems. Physiol. Rev. 86, 747-803 (2006). (Pubitemid 44033382)
-
(2006)
Physiological Reviews
, vol.86
, Issue.3
, pp. 747-803
-
-
Paul, M.1
Mehr, A.P.2
Kreutz, R.3
-
96
-
-
2142653518
-
The role of the pancreatic renin-angiotensin system in acinar digestive enzyme secretion and in acute pancreatitis
-
DOI 10.1016/j.regpep.2004.02.003, PII S0167011504000394
-
Tsang, S. W. et al. The role of the pancreatic renin-angiotensin system in acinar digestive enzyme secretion and in acute pancreatitis. Regul. Pept. 119, 213-219 (2004). (Pubitemid 38553840)
-
(2004)
Regulatory Peptides
, vol.119
, Issue.3
, pp. 213-219
-
-
Tsang, S.W.1
Cheng, C.H.K.2
Leung, P.S.3
-
97
-
-
0345276709
-
2 receptor antagonists and their effects on changes in the severity of pancreatitis
-
DOI 10.1016/S1357-2725(03)00257-7
-
Tsang, S. W. et al. Prophylactic and therapeutic treatments with AT 1 and AT 2 receptor antagonists and their effects on changes in the severity of pancreatitis. Int. J. Biochem. Cell Biol. 36, 330-339 (2004). (Pubitemid 37487767)
-
(2004)
International Journal of Biochemistry and Cell Biology
, vol.36
, Issue.2
, pp. 330-339
-
-
Tsang, S.W.1
Ip, S.P.2
Leung, P.S.3
-
98
-
-
0037381733
-
Angiotensin-converting enzyme inhibitor attenuates pancreatic inflammation and fibrosis in male Wistar Bonn/Kobori rats
-
DOI 10.1053/gast.2003.50147
-
Kuno, A. et al. Angiotensin-converting enzyme inhibitor attenuates pancreatic inflammation and fibrosis in male Wistar Bonn/Kobori rats. Gastroenterology 124, 1010-1019 (2003). (Pubitemid 36389804)
-
(2003)
Gastroenterology
, vol.124
, Issue.4
, pp. 1010-1019
-
-
Kuno, A.1
Yamada, T.2
Masuda, K.3
Ogawa, K.4
Sogawa, M.5
Nakamura, S.6
Nakazawa, T.7
Ohara, H.8
Nomura, T.9
Joh, T.10
Shirai, T.11
Itoh, M.12
-
99
-
-
59449084697
-
Protective role of angiotensin II type 2 receptor signaling in a mouse model of pancreatic fibrosis
-
Ulmasov, B. et al. Protective role of angiotensin II type 2 receptor signaling in a mouse model of pancreatic fibrosis. Am. J. Physiol. Gastrointest. Liver Physiol. 296, G284-G294 (2009).
-
(2009)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.296
-
-
Ulmasov, B.1
-
100
-
-
79953826393
-
Involvement of angiotensin II and reactive oxygen species in pancreatic fibrosis
-
Sakurai, T. et al. Involvement of angiotensin II and reactive oxygen species in pancreatic fibrosis. Pancreatology 11 (Suppl. 2), 7-13 (2011).
-
(2011)
Pancreatology
, vol.11
, Issue.SUPPL. 2
, pp. 7-13
-
-
Sakurai, T.1
-
101
-
-
77954376035
-
Angiotensin II signaling through the AT1a and AT1b receptors does not have a role in the development of cerulein-induced chronic pancreatitis in the mouse
-
Ulmasov, B. et al. Angiotensin II signaling through the AT1a and AT1b receptors does not have a role in the development of cerulein-induced chronic pancreatitis in the mouse. Am. J. Physiol. Gastrointest. Liver Physiol. 299, G70-G80 (2010).
-
(2010)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.299
-
-
Ulmasov, B.1
-
102
-
-
33947115888
-
Metabolic actions of angiotensin receptor antagonists: PPAR-γ agonist actions or a class effect?
-
DOI 10.1016/j.coph.2006.11.008, PII S147148920700029X
-
Ernsberger, P. et al. Metabolic actions of angiotensin receptor antagonists: PPAR-gamma agonist actions or a class effect? Curr. Opin. Pharmacol. 7, 140-145 (2007). (Pubitemid 46404747)
-
(2007)
Current Opinion in Pharmacology
, vol.7
, Issue.2
, pp. 140-145
-
-
Ernsberger, P.1
Koletsky, R.J.2
-
103
-
-
84856582504
-
Tocotrienol as a potential anticancer agent
-
Ling, M. T. et al. Tocotrienol as a potential anticancer agent. Carcinogenesis 33, 233-239 (2012).
-
(2012)
Carcinogenesis
, vol.33
, pp. 233-239
-
-
Ling, M.T.1
-
104
-
-
79751528918
-
Alpha-Tocopherol treatment ameliorates chronic pancreatitis in an experimental rat model induced by trinitrobenzene sulfonic acid
-
Li, X. C. et al. alpha-Tocopherol treatment ameliorates chronic pancreatitis in an experimental rat model induced by trinitrobenzene sulfonic acid. Pancreatology 11, 5-11 (2011).
-
(2011)
Pancreatology
, vol.11
, pp. 5-11
-
-
Li, X.C.1
-
105
-
-
34249992834
-
Tocotrienols induce apoptosis and autophagy in rat pancreatic stellate cells through the mitochondrial death pathway
-
DOI 10.1053/j.gastro.2007.03.107, PII S0016508507006336
-
Rickmann, M. et al. Tocotrienols induce apoptosis and autophagy in rat pancreatic stellate cells through the mitochondrial death pathway. Gastroenterology 132, 2518-2532 (2007). (Pubitemid 46890868)
-
(2007)
Gastroenterology
, vol.132
, Issue.7
, pp. 2518-2532
-
-
Rickmann, M.1
Vaquero, E.C.2
Malagelada, J.R.3
Molero, X.4
-
106
-
-
80052998719
-
Comparison of antioxidative and antifibrotic effects of alpha-tocopherol with those of tocotrienol-rich fraction in a rat model of chronic pancreatitis
-
Jiang, F. et al. Comparison of antioxidative and antifibrotic effects of alpha-tocopherol with those of tocotrienol-rich fraction in a rat model of chronic pancreatitis. Pancreas 40, 1091-1096 (2011).
-
(2011)
Pancreas
, vol.40
, pp. 1091-1096
-
-
Jiang, F.1
-
107
-
-
0037181332
-
Free radical studies of ellagic acid, a natural phenolic antioxidant
-
DOI 10.1021/jf011275g
-
Priyadarsini, K. I. et al. Free radical studies of ellagic acid, a natural phenolic antioxidant. J. Agric. Food Chem. 50, 2200-2206 (2002). (Pubitemid 34260032)
-
(2002)
Journal of Agricultural and Food Chemistry
, vol.50
, Issue.7
, pp. 2200-2206
-
-
Priyadarsini, K.I.1
Khopde, S.M.2
Kumar, S.S.3
Mohan, H.4
-
108
-
-
0037169308
-
Effect of ellagic acid on gastric damage induced in ischemic rat stomachs following ammonia or reperfusion
-
DOI 10.1016/S0024-3205(01)01493-X, PII S002432050101493X
-
Iino, T. et al. Effect of ellagic acid on gastric damage induced in ischemic rat stomachs following ammonia or reperfusion. Life Sci. 70, 1139-1150 (2002). (Pubitemid 34137082)
-
(2002)
Life Sciences
, vol.70
, Issue.10
, pp. 1139-1150
-
-
Iino, T.1
Tashima, K.2
Umeda, M.3
Ogawa, Y.4
Takeeda, M.5
Takata, K.6
Takeuchi, K.7
-
110
-
-
23744492100
-
Ellagic acid blocks activation of pancreatic stellate cells
-
DOI 10.1016/j.bcp.2005.06.008, PII S0006295205003941
-
Masamune, A. et al. Ellagic acid blocks activation of pancreatic stellate cells. Biochem. Pharmacol. 70, 869-878 (2005). (Pubitemid 41138851)
-
(2005)
Biochemical Pharmacology
, vol.70
, Issue.6
, pp. 869-878
-
-
Masamune, A.1
Satoh, M.2
Kikuta, K.3
Suzuki, N.4
Satoh, K.5
Shimosegawa, T.6
-
111
-
-
63249133855
-
Ellagic acid inhibits pancreatic fibrosis in male Wistar Bonn/Kobori rats
-
Suzuki, N. et al. Ellagic acid inhibits pancreatic fibrosis in male Wistar Bonn/Kobori rats. Dig. Dis. Sci. 54, 802-810 (2009).
-
(2009)
Dig. Dis. Sci.
, vol.54
, pp. 802-810
-
-
Suzuki, N.1
-
112
-
-
33747105839
-
10 by derivative spectroscopy and HPLC
-
DOI 10.1016/j.talanta.2006.02.057, PII S0039914006001858
-
Ratnam, D. V. et al. Simultaneous analysis of ellagic acid and coenzyme Q(10) by derivative spectroscopy and HPLC. Talanta 70, 387-391 (2006). (Pubitemid 44223637)
-
(2006)
Talanta
, vol.70
, Issue.2
, pp. 387-391
-
-
Ratnam, D.V.1
Bhardwaj, V.2
Kumar, M.N.V.R.3
-
113
-
-
82955217764
-
Epigallocatechin gallate suppresses peritoneal fibrosis in mice
-
Kitamura, M. et al. Epigallocatechin gallate suppresses peritoneal fibrosis in mice. Chem. Biol. Interact. 195, 95-104 (2012).
-
(2012)
Chem. Biol. Interact.
, vol.195
, pp. 95-104
-
-
Kitamura, M.1
-
114
-
-
70349303936
-
Formation of vitamin A lipid droplets in pancreatic stellate cells requires albumin
-
Kim, N. et al. Formation of vitamin A lipid droplets in pancreatic stellate cells requires albumin. Gut 58, 1382-1390 (2009).
-
(2009)
Gut
, vol.58
, pp. 1382-1390
-
-
Kim, N.1
-
115
-
-
65049091645
-
Signal transduction in pancreatic stellate cells
-
Masamune, A. et al. Signal transduction in pancreatic stellate cells. J. Gastroenterol. 44, 249-260 (2009).
-
(2009)
J. Gastroenterol.
, vol.44
, pp. 249-260
-
-
Masamune, A.1
-
116
-
-
0035872250
-
A heterologous 3-D coculture model of breast tumor cells and fibroblasts to study tumor-associated fibroblast differentiation
-
DOI 10.1006/excr.2001.5210
-
Kunz-Schughart, L. A. et al. A heterologous 3?D coculture model of breast tumor cells and fibroblasts to study tumor-associated fibroblast differentiation. Exp. Cell Res. 266, 74-86 (2001). (Pubitemid 32989044)
-
(2001)
Experimental Cell Research
, vol.266
, Issue.1
, pp. 74-86
-
-
Kunz-Schughart, L.A.1
Heyder, P.2
Schroeder, J.3
Knuechel, R.4
-
117
-
-
0035871979
-
Human antibody derivatives against the fibroblast activation protein for tumor stroma targeting of carcinomas
-
DOI 10.1002/1097-0215(200 102)9999:9999<::AID-IJC1 170>3.0. CO;2-U
-
Mersmann, M. et al. Human antibody derivatives against the fibroblast activation protein for tumor stroma targeting of carcinomas. Int. J. Cancer 92, 240-248 (2001). (Pubitemid 32225376)
-
(2001)
International Journal of Cancer
, vol.92
, Issue.2
, pp. 240-248
-
-
Mersmann, M.1
Schmidt, A.2
Rippmann, J.F.3
West, T.4
Brocks, B.5
Rettig, W.J.6
Garin-Chesa, P.7
Pfizenmaier, K.8
Moosmayer, D.9
-
118
-
-
0037102412
-
Promotion of tumor growth by murine fibroblast activation protein, a serine protease, in an animal model
-
Cheng, J. D. et al. Promotion of tumor growth by murine fibroblast activation protein, a serine protease, in an animal model. Cancer Res. 62, 4767-4772 (2002).
-
(2002)
Cancer Res.
, vol.62
, pp. 4767-4772
-
-
Cheng, J.D.1
-
119
-
-
33745837774
-
Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake
-
DOI 10.1172/JCI26532
-
Loeffler, M. et al. Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake. J. Clin. Invest. 116, 1955-1962 (2006). (Pubitemid 44033319)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.7
, pp. 1955-1962
-
-
Loeffler, M.1
Kruger, J.A.2
Niethammer, A.G.3
Reisfeld, R.A.4
-
120
-
-
78149298209
-
Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha
-
Kraman, M. et al. Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha. Science 330, 827-830 (2010).
-
(2010)
Science
, vol.330
, pp. 827-830
-
-
Kraman, M.1
-
121
-
-
77957150824
-
Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma
-
Morris, J. P. 4th, Wang, S. C. & Hebrok, M. KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma. Nat. Rev. Cancer 10, 683-695 (2010).
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 683-695
-
-
Morris, J.P.1
Wang, S.C.2
Hedgehog Kras, H.M.3
-
122
-
-
52149119128
-
A paracrine requirement for hedgehog signalling in cancer
-
Yauch, R. L. et al. A paracrine requirement for hedgehog signalling in cancer. Nature 455, 406-410 (2008).
-
(2008)
Nature
, vol.455
, pp. 406-410
-
-
Yauch, R.L.1
-
123
-
-
63149124772
-
Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis
-
Tian, H. et al. Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis. Proc. Natl Acad. Sci. USA 106, 4254-4259 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 4254-4259
-
-
Tian, H.1
-
124
-
-
79953154967
-
CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans
-
Beatty, G. L. et al. CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans. Science 331, 1612-1616 (2011).
-
(2011)
Science
, vol.331
, pp. 1612-1616
-
-
Beatty, G.L.1
-
125
-
-
29244437554
-
Pancreatic stellate cells: New kids become mature
-
DOI 10.1136/gut.2005.074427
-
Pinzani, M. Pancreatic stellate cells: new kids become mature. Gut 55, 12-14 (2006). (Pubitemid 41820628)
-
(2006)
Gut
, vol.55
, Issue.1
, pp. 12-14
-
-
Pinzani, M.1
-
126
-
-
0001631287
-
Studying artificial life with cellular automata
-
Langton, C. Studying artificial life with cellular automata. Physica D: Nonlinear Phenomena 22, 120-149 (1986).
-
(1986)
Physica D: Nonlinear Phenomena
, vol.22
, pp. 120-149
-
-
Langton, C.1
-
127
-
-
0346503889
-
Talking about a revolution: The impact of site-specific recombinases on genetic analyses in mice
-
DOI 10.1016/S1534-5807(03)00399-X, PII S153458070300399X
-
Branda, C. S. et al. Talking about a revolution: The impact of site-specific recombinases on genetic analyses in mice. Dev. Cell 6, 7-28 (2004). (Pubitemid 38089202)
-
(2004)
Developmental Cell
, vol.6
, Issue.1
, pp. 7-28
-
-
Branda, C.S.1
Dymecki, S.M.2
|