메뉴 건너뛰기




Volumn 120, Issue 16, 2012, Pages 3280-3287

Tumor-associated macrophages predict inferior outcomes in classic Hodgkin lymphoma: A correlative study from the E2496 Intergroup trial

(14)  Tan, King L a   Scott, David W a   Hong, Fangxin b   Kahl, Brad S c   Fisher, Richard I d   Bartlett, Nancy L e   Advani, Ranjana H f   Buckstein, Rena g   Rimsza, Lisa M h   Connors, Joseph M a   Steidl, Christian a   Gordon, Leo I i   Horning, Sandra J j   Gascoyne, Randy D a  


Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; BLEOMYCIN; CD163 ANTIGEN; CD68 ANTIGEN; CHLORDANE; DACARBAZINE; DOXORUBICIN; ETOPOSIDE; HEMOGLOBIN; MECHLOROETHAMINE; PREDNISONE; UNCLASSIFIED DRUG; VINBLASTINE; VINCRISTINE;

EID: 84868116570     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-04-421057     Document Type: Article
Times cited : (183)

References (36)
  • 1
    • 84866755983 scopus 로고    scopus 로고
    • The International Prognostic Factor Project Score (IPS) in advanced stage Hodgkin lymphoma has limited utility in patients treated in the modern era
    • Moccia AM, Donaldson J, Chhanabhai M, et al. The International Prognostic Factor Project Score (IPS) in advanced stage Hodgkin lymphoma has limited utility in patients treated in the modern era. J Clin Oncol. 2012;30(27):3383-3388.
    • (2012) J Clin Oncol. , vol.30 , Issue.27 , pp. 3383-3388
    • Moccia, A.M.1    Donaldson, J.2    Chhanabhai, M.3
  • 2
    • 84859962776 scopus 로고    scopus 로고
    • Stage IV and age over 45 years are the only prognostic factors of the International Prognostic Score for the outcome of advanced Hodgkin lymphoma in the Spanish Hodgkin Lymphoma Study Group series
    • Guisado-Vasco P, Arranz-Saez R, Canales M, et al. Stage IV and age over 45 years are the only prognostic factors of the International Prognostic Score for the outcome of advanced Hodgkin lymphoma in the Spanish Hodgkin Lymphoma Study Group series. Leuk Lymphoma. 2012;53(5):812-819.
    • (2012) Leuk Lymphoma. , vol.53 , Issue.5 , pp. 812-819
    • Guisado-Vasco, P.1    Arranz-Saez, R.2    Canales, M.3
  • 3
    • 0032548107 scopus 로고    scopus 로고
    • A prognostic score for advanced Hodgkin's disease: International Prognostic Factors Project on Advanced Hodgkin's Disease
    • Hasenclever D, Diehl V. A prognostic score for advanced Hodgkin's disease: International Prognostic Factors Project on Advanced Hodgkin's Disease. N Engl J Med. 1998;339(21):1506-1514.
    • (1998) N Engl J Med. , vol.339 , Issue.21 , pp. 1506-1514
    • Hasenclever, D.1    Diehl, V.2
  • 4
    • 79955877897 scopus 로고    scopus 로고
    • Molecular pathogenesis of Hodgkin's lymphoma: Increasing evidence of the importance of the microenvironment
    • Steidl C, Connors JM, Gascoyne RD. Molecular pathogenesis of Hodgkin's lymphoma: increasing evidence of the importance of the microenvironment. J Clin Oncol. 2011;29(14):1812-1826.
    • (2011) J Clin Oncol. , vol.29 , Issue.14 , pp. 1812-1826
    • Steidl, C.1    Connors, J.M.2    Gascoyne, R.D.3
  • 5
    • 79551642617 scopus 로고    scopus 로고
    • Macrophages predict treatment outcome in Hodgkin's lymphoma
    • Steidl C, Farinha P, Gascoyne RD. Macrophages predict treatment outcome in Hodgkin's lymphoma. Haematologica. 2011;96(2):186-189.
    • (2011) Haematologica , vol.96 , Issue.2 , pp. 186-189
    • Steidl, C.1    Farinha, P.2    Gascoyne, R.D.3
  • 6
    • 77949345555 scopus 로고    scopus 로고
    • Tumor-associated macrophages and survival in classic Hodgkin's lymphoma
    • Steidl C, Lee T, Shah SP, et al. Tumor-associated macrophages and survival in classic Hodgkin's lymphoma. N Engl J Med. 2010;362(10):875-885.
    • (2010) N Engl J Med. , vol.362 , Issue.10 , pp. 875-885
    • Steidl, C.1    Lee, T.2    Shah, S.P.3
  • 8
    • 84873087771 scopus 로고    scopus 로고
    • CD68+ tumor-associated macrophages predict unfavorable treatment outcomes in classic Hodgkin's lymphoma in correlation with early FDGPET assessment results [abstract]
    • Touati M, Delage-Corre M, Monteil J, et al. CD68+ tumor-associated macrophages predict unfavorable treatment outcomes in classic Hodgkin's lymphoma in correlation with early FDGPET assessment results [abstract]. Blood (ASH Annual Meeting Abstracts). 2011;118(21):1558.
    • (2011) Blood (ASH Annual Meeting Abstracts) , vol.118 , Issue.21 , pp. 1558
    • Touati, M.1    Delage-Corre, M.2    Monteil, J.3
  • 9
    • 84873097028 scopus 로고    scopus 로고
    • Lymphoma associated macrophages predict survival in uniformly treated patients with classical Hodgkin lymphoma [abstract]
    • Farinha P, Rodrigues S, Fernandes T, et al. Lymphoma associated macrophages predict survival in uniformly treated patients with classical Hodgkin lymphoma [abstract]. Mod Pathol. 2011;24(1 Suppl):1257.
    • (2011) Mod Pathol. , vol.24 , Issue.1 SUPPL. , pp. 1257
    • Farinha, P.1    Rodrigues, S.2    Fernandes, T.3
  • 10
    • 84873091214 scopus 로고    scopus 로고
    • Expression of FOXP3, CD68 and CD20 at diagnosis in the microenvironment of classical Hodgkin lymphoma is predictive of outcome [prepublished online ahead of print October 8, 2012]
    • Greaves P, Clear A, Coutinho R, et al. Expression of FOXP3, CD68 and CD20 at diagnosis in the microenvironment of classical Hodgkin lymphoma is predictive of outcome [prepublished online ahead of print October 8, 2012]. J Clin Oncol.
    • J Clin Oncol
    • Greaves, P.1    Clear, A.2    Coutinho, R.3
  • 11
    • 79551623661 scopus 로고    scopus 로고
    • Macrophages and mast cells infiltration are biomarkers of primary refractory Hodgkin's lymphoma [abstract]
    • Deau B, Bachy E, Ribrag V, et al. Macrophages and mast cells infiltration are biomarkers of primary refractory Hodgkin's lymphoma [abstract]. Blood (ASH Annual Meeting Abstracts). 2010;116(21):3881.
    • (2010) Blood (ASH Annual Meeting Abstracts) , vol.116 , Issue.21 , pp. 3881
    • Deau, B.1    Bachy, E.2    Ribrag, V.3
  • 12
    • 84863961531 scopus 로고    scopus 로고
    • Immunohistochemical markers for tumor associated macrophages and survival in advanced classical Hodgkin lymphoma
    • Sánchez-Espiridión B, Martin-Moreno AM, Montalban C, et al. Immunohistochemical markers for tumor associated macrophages and survival in advanced classical Hodgkin lymphoma. Haematologica. 2012;97(7):1080-1084.
    • (2012) Haematologica , vol.97 , Issue.7 , pp. 1080-1084
    • Sánchez-Espiridión, B.1    Martin-Moreno, A.M.2    Montalban, C.3
  • 13
    • 79251581263 scopus 로고    scopus 로고
    • Refined prognostic role of CD68-positive tumor macrophages in the context of the cellular micromilieu of classical Hodgkin lymphoma
    • Tzankov A, Matter MS, Dirnhofer S. Refined prognostic role of CD68-positive tumor macrophages in the context of the cellular micromilieu of classical Hodgkin lymphoma. Pathobiology. 2010;77(6):301-308.
    • (2010) Pathobiology. , vol.77 , Issue.6 , pp. 301-308
    • Tzankov, A.1    Matter, M.S.2    Dirnhofer, S.3
  • 15
    • 84858293587 scopus 로고    scopus 로고
    • CD68 and CD163 as prognostic factors for Korean patients with Hodgkin lymphoma
    • Yoon DH, Koh YW, Kang HJ, et al. CD68 and CD163 as prognostic factors for Korean patients with Hodgkin lymphoma. Eur J Haematol. 2012;88(4):292-305.
    • (2012) Eur J Haematol. , vol.88 , Issue.4 , pp. 292-305
    • Yoon, D.H.1    Koh, Y.W.2    Kang, H.J.3
  • 16
    • 79551650002 scopus 로고    scopus 로고
    • Tumor-infiltrating macrophages correlate with adverse prognosis and Epstein-Barr virus status in classical Hodgkin's lymphoma
    • Kamper P, Bendix K, Hamilton-Dutoit S, Honore B, Nyengaard JR, d'Amore F. Tumor-infiltrating macrophages correlate with adverse prognosis and Epstein-Barr virus status in classical Hodgkin's lymphoma. Haematologica. 2011;96(2):269-276.
    • (2011) Haematologica , vol.96 , Issue.2 , pp. 269-276
    • Kamper, P.1    Bendix, K.2    Hamilton-Dutoit, S.3    Honore, B.4    Nyengaard, J.R.5    D'Amore, F.6
  • 17
    • 80855130756 scopus 로고    scopus 로고
    • Prognostic implication of types of tumor-associated macrophages in Hodgkin lymphoma
    • Zaki MA, Wada N, Ikeda J, et al. Prognostic implication of types of tumor-associated macrophages in Hodgkin lymphoma. Virchows Arch. 2011;459(4):361-366.
    • (2011) Virchows Arch. , vol.459 , Issue.4 , pp. 361-366
    • Zaki, M.A.1    Wada, N.2    Ikeda, J.3
  • 18
    • 84863921794 scopus 로고    scopus 로고
    • The prognostic value of biologic markers in classical Hodgkin lymphoma (CHL) patients [abstract]
    • Agostinelli C, Gallamini A, Rigacci L, et al. The prognostic value of biologic markers in classical Hodgkin lymphoma (CHL) patients [abstract]. Ann Oncol. 2011;22(Suppl 4):153-154.
    • (2011) Ann Oncol. , vol.22 , Issue.SUPPL. 4 , pp. 153-154
    • Agostinelli, C.1    Gallamini, A.2    Rigacci, L.3
  • 19
    • 84862777574 scopus 로고    scopus 로고
    • CD163 versus CD68 in tumor associated macrophages of classical Hodgkin lymphoma
    • Harris JA, Jain S, Ren Q, Zarineh A, Liu C, Ibrahim S. CD163 versus CD68 in tumor associated macrophages of classical Hodgkin lymphoma. Diagn Pathol. 2012;7:12.
    • (2012) Diagn Pathol. , vol.7 , pp. 12
    • Harris, J.A.1    Jain, S.2    Ren, Q.3    Zarineh, A.4    Liu, C.5    Ibrahim, S.6
  • 20
    • 84857534118 scopus 로고    scopus 로고
    • Lack of association of tumor-associated macrophages with clinical outcome in patients with classical Hodgkin's lymphoma
    • Azambuja D, Natkunam Y, Biasoli I, et al. Lack of association of tumor-associated macrophages with clinical outcome in patients with classical Hodgkin's lymphoma. Ann Oncol. 2012;23(3):736-742.
    • (2012) Ann Oncol. , vol.23 , Issue.3 , pp. 736-742
    • Azambuja, D.1    Natkunam, Y.2    Biasoli, I.3
  • 22
    • 8444244786 scopus 로고    scopus 로고
    • X-tile: A new bio-informatics tool for biomarker assessment and outcome-based cut-point optimization
    • DOI 10.1158/1078-0432.CCR-04-0713
    • Camp RL, Dolled-Filhart M, Rimm DL. X-tile: a new bio-informatics tool for biomarker assessment and outcome-based cut-point optimization. Clin Cancer Res. 2004;10(21):7252-7259. (Pubitemid 39487712)
    • (2004) Clinical Cancer Research , vol.10 , Issue.21 , pp. 7252-7259
    • Camp, R.L.1    Dolled-Filhart, M.2    Rimm, D.L.3
  • 23
    • 3042701254 scopus 로고    scopus 로고
    • Macrophage specificity of three anti-CD68 monoclonal antibodies (KP1, EBM11, and PGM1) widely used for immunohistochemistry and flow cytometry
    • DOI 10.1136/ard.2003.013029
    • Kunisch E, Fuhrmann R, Roth A, Winter R, Lungershausen W, Kinne RW. Macrophage specificity of three anti-CD68 monoclonal antibodies (KP1, EBM11, and PGM1) widely used for immunohistochemistry and flow cytometry. Ann Rheum Dis. 2004;63(7):774-784. (Pubitemid 38850447)
    • (2004) Annals of the Rheumatic Diseases , vol.63 , Issue.7 , pp. 774-784
    • Kunisch, E.1    Fuhrmann, R.2    Roth, A.3    Winter, R.4    Lungershausen, W.5    Kinne, R.W.6
  • 24
    • 7244238190 scopus 로고    scopus 로고
    • CD163: A specific marker of macrophages in paraffin-embedded tissue samples
    • DOI 10.1309/QHD6-YFN8-1KQX-UUH6
    • Lau SK, Chu PG, Weiss LM. CD163: a specific marker of macrophages in paraffin-embedded tissue samples. Am J Clin Pathol. 2004;122(5):794-801. (Pubitemid 39434761)
    • (2004) American Journal of Clinical Pathology , vol.122 , Issue.5 , pp. 794-801
    • Lau, S.K.1    Chu, P.G.2    Weiss, L.M.3
  • 25
    • 83455203338 scopus 로고    scopus 로고
    • Identification and manipulation of tumor associated macrophages in human cancers
    • Heusinkveld M, van der Burg SH. Identification and manipulation of tumor associated macrophages in human cancers. J Transl Med. 2011;9:216.
    • (2011) J Transl Med. , vol.9 , pp. 216
    • Heusinkveld, M.1    Van Der Burg, S.H.2
  • 26
    • 84855346705 scopus 로고    scopus 로고
    • Systematic validation of specific phenotypic markers for in vitro polarized human macrophages
    • Ambarus CA, Krausz S, van Eijk M, et al. Systematic validation of specific phenotypic markers for in vitro polarized human macrophages. J Immunol Methods. 2012;375(2):196-206.
    • (2012) J Immunol Methods. , vol.375 , Issue.2 , pp. 196-206
    • Ambarus, C.A.1    Krausz, S.2    Van Eijk, M.3
  • 27
    • 77950627035 scopus 로고    scopus 로고
    • Scavenger receptor CD163, a Jack-of-all-trades and potential target for cell-directed therapy
    • Van Gorp H, Delputte PL, Nauwynck HJ. Scavenger receptor CD163, a Jack-of-all-trades and potential target for cell-directed therapy. Mol Immunol. 2010;47(8):1650-1660.
    • (2010) Mol Immunol. , vol.47 , Issue.8 , pp. 1650-1660
    • Van Gorp, H.1    Delputte, P.L.2    Nauwynck, H.J.3
  • 28
    • 80355146399 scopus 로고    scopus 로고
    • Transcriptional regulation of macrophage polarization: Enabling diversity with identity
    • Lawrence T, Natoli G. Transcriptional regulation of macrophage polarization: enabling diversity with identity. Nat Rev Immunol. 2011;11(11):750-761.
    • (2011) Nat Rev Immunol. , vol.11 , Issue.11 , pp. 750-761
    • Lawrence, T.1    Natoli, G.2
  • 29
    • 80052138920 scopus 로고    scopus 로고
    • Cancer-promoting tumor-associated macrophages: New vistas and open questions
    • Mantovani A, Germano G, Marchesi F, Locatelli M, Biswas SK. Cancer-promoting tumor-associated macrophages: new vistas and open questions. Eur J Immunol. 2011;41(9):2522-2525.
    • (2011) Eur J Immunol. , vol.41 , Issue.9 , pp. 2522-2525
    • Mantovani, A.1    Germano, G.2    Marchesi, F.3    Locatelli, M.4    Biswas, S.K.5
  • 30
    • 80355131976 scopus 로고    scopus 로고
    • Protective and pathogenic functions of macrophage subsets
    • Murray PJ, Wynn TA. Protective and pathogenic functions of macrophage subsets. Nat Rev Immunol. 2011;11(11):723-737.
    • (2011) Nat Rev Immunol. , vol.11 , Issue.11 , pp. 723-737
    • Murray, P.J.1    Wynn, T.A.2
  • 31
    • 84855817522 scopus 로고    scopus 로고
    • Immunology in the clinic review series; focus on cancer: Tumour-associated macrophages: Undisputed stars of the inflammatory tumour microenvironment
    • Allavena P, Mantovani A. Immunology in the clinic review series; focus on cancer: tumour-associated macrophages: undisputed stars of the inflammatory tumour microenvironment. Clin Exp Immunol. 2012;167(2):195-205.
    • (2012) Clin Exp Immunol. , vol.167 , Issue.2 , pp. 195-205
    • Allavena, P.1    Mantovani, A.2
  • 32
    • 84868131613 scopus 로고    scopus 로고
    • The role of tumor-associated macrophage in tumor progression
    • Fukuda K, Kobayashi A, Watabe K. The role of tumor-associated macrophage in tumor progression. Front Biosci (Schol Ed). 2012;4(Suppl 4): 787):787-798.
    • (2012) Front Biosci (Schol Ed). , vol.4 , Issue.787 SUPPL. 4 , pp. 787-798
    • Fukuda, K.1    Kobayashi, A.2    Watabe, K.3
  • 33
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser DM, Edwards JP. Exploring the full spectrum of macrophage activation. Nat Rev Immunol. 2008;8(12):958-969.
    • (2008) Nat Rev Immunol. , vol.8 , Issue.12 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 34
    • 84255197264 scopus 로고    scopus 로고
    • Transcriptomic analyses of murine resolution-phase macrophages
    • Stables MJ, Shah S, Camon EB, et al. Transcriptomic analyses of murine resolution-phase macrophages. Blood. 2011;118(26):e192-e208.
    • (2011) Blood , vol.118 , Issue.26
    • Stables, M.J.1    Shah, S.2    Camon, E.B.3
  • 35
    • 79955493270 scopus 로고    scopus 로고
    • The viral load of Epstein-Barr virus (EBV) DNA in peripheral blood predicts for biological and clinical characteristics in Hodgkin lymphoma
    • Hohaus S, Santangelo R, Giachelia M, et al. The viral load of Epstein-Barr virus (EBV) DNA in peripheral blood predicts for biological and clinical characteristics in Hodgkin lymphoma. Clin Cancer Res. 2011;17(9):2885-2892.
    • (2011) Clin Cancer Res. , vol.17 , Issue.9 , pp. 2885-2892
    • Hohaus, S.1    Santangelo, R.2    Giachelia, M.3
  • 36
    • 63849185609 scopus 로고    scopus 로고
    • Molecular profiling of classical Hodgkin lymphoma tissues uncovers variations in the tumor microenvironment and correlations with EBV infection and outcome
    • Chetaille B, Bertucci F, Finetti P, et al. Molecular profiling of classical Hodgkin lymphoma tissues uncovers variations in the tumor microenvironment and correlations with EBV infection and outcome. Blood. 2009;113(12):2765-3775.
    • (2009) Blood , vol.113 , Issue.12 , pp. 2765-3775
    • Chetaille, B.1    Bertucci, F.2    Finetti, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.