Xenobiotic metabolism in differentiated human bronchial epithelial cells

Archives of Toxicology

Volumn 91, Issue 5, 2017, Pages 2093-2105

  Boei, Jan J W A ^a   Vermeulen, Sylvia ^a   Klein, Binie ^a   Hiemstra, Pieter S ^a   Verhoosel, Renate M ^a   Jennen, Danyel G J ^b   Lahoz, Agustin ^c   Gmuender, Hans ^d   Vrieling, Harry ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c HOSPITAL UNIVERSITARIO LA FE   (Spain)

^d GENEDATA AG   (Switzerland)

Author keywords

Bronchial epithelial cells; Cytochrome P450; Gene expression profiling; Lung; Metabolic activity

Indexed keywords

ADH1C PROTEIN; ALDH1A1 PROTEIN; CYP2F1 PROTEIN; CYP4X1 PROTEIN; CYP4Z1 PROTEIN; CYTOCHROME P450 2B6; CYTOCHROME P450 4B1; GLUTATHIONE TRANSFERASE A1; PROTEIN; UNCLASSIFIED DRUG; 1,2,5,6-DIBENZANTHRACENE; BENZO[A]PYRENE; BENZ[A]ANTHRACENE DERIVATIVE; CYTOCHROME; CYTOCHROME P420; ENZYME; POLYCHLORINATED DIBENZODIOXIN; XENOBIOTIC AGENT;

AIRWAY EPITHELIUM CELL; ARTICLE; BRONCHIAL EPITHELIAL CELL; BRONCHUS EPITHELIUM; EPITHELIUM CELL; GENE ACTIVITY; GENE EXPRESSION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; LONGITUDINAL STUDY; PRIORITY JOURNAL; TRANSCRIPTION INITIATION; XENOBIOTIC METABOLISM; BIOTRANSFORMATION; BRONCHUS; CELL CULTURE TECHNIQUE; CELL DIFFERENTIATION; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PROCEDURES; REPRODUCIBILITY;

BENZ(A)ANTHRACENES; BENZO(A)PYRENE; BIOTRANSFORMATION; BRONCHI; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CYTOCHROMES; ENZYMES; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; HUMANS; POLYCHLORINATED DIBENZODIOXINS; REPRODUCIBILITY OF RESULTS; XENOBIOTICS;

EID: 84991094050     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-016-1868-7     Document Type: Article

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