Thirdhand cigarette smoke causes stress-induced mitochondrial hyperfusion and alters the transcriptional profile of stem cells

Toxicological Sciences

Volumn 153, Issue 1, 2016, Pages 55-69

  Bahl, Vasundhra ^a   Johnson, Kimberly ^a   Phandthong, Rattapol ^a   Zahedi, Atena ^a,b   Schick, Suzaynn F ^c   Talbot, Prue ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b University of California Riverside   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cigarette; Fusion; Mitochondria; Oxidation; Reactive oxygen species; Smoke; Stress; Thirdhand smoke; Tobacco

Indexed keywords

ADENOSINE TRIPHOSPHATE; CIGARETTE SMOKE; MITOCHONDRIAL PROTEIN; PROTEIN BID; SUPEROXIDE; THIRDHAND CIGARETTE SMOKE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 2; MATRIX METALLOPROTEINASE; REACTIVE OXYGEN METABOLITE;

AIFM2 GENE; APOPTOSIS; ARTICLE; BBC3 GENE; CELL PROLIFERATION; CONTROLLED STUDY; FIS1 GENE; GENE; GENE EXPRESSION; GENETIC TRANSCRIPTION; GLYCOLYSIS; HUMAN; HUMAN CELL; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL HYPERFUSION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOLECULAR BIOLOGY; MORPHOLOGY; OXIDATION; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; PROTEIN EXPRESSION; STEM CELL; UCP4 GENE; UCP5 GENE; BIOSYNTHESIS; CELL CULTURE; CULTURE MEDIUM; CYTOLOGY; ENZYMOLOGY; GENE EXPRESSION PROFILING; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY; POLYMERASE CHAIN REACTION; SMOKE; TOBACCO;

ADENOSINE TRIPHOSPHATE; CELL PROLIFERATION; CELLS, CULTURED; CULTURE MEDIA; GENE EXPRESSION PROFILING; HUMANS; MATRIX METALLOPROTEINASES; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; OXIDATION-REDUCTION; POLYMERASE CHAIN REACTION; REACTIVE OXYGEN SPECIES; SMOKE; STEM CELLS; TOBACCO PRODUCTS; TRANSCRIPTION, GENETIC;

EID: 84991030571     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfw102     Document Type: Article

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