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Volumn 42, Issue 3, 2017, Pages 777-787

The Role of Ca2+ Imbalance in the Induction of Acute Oxidative Stress and Cytotoxicity in Cultured Rat Cerebellar Granule Cells Challenged with Tetrabromobisphenol A

Author keywords

Brominated flame retardants; Neuroprotection; NMDA receptors; Primary neuronal cultures; Reactive oxygen species; Ryanodine receptors

Indexed keywords

CALCIUM ION; CATALASE; DIZOCILPINE; GLUTATHIONE; REACTIVE OXYGEN METABOLITE; RYANODINE; TETRABROMOBISPHENOL A; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; CARRIER PROTEIN; CYCLOSPORIN; CYTOTOXIN; FLAME RETARDANT; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; POLLUTANT; POLYBROMINATED BIPHENYL; SCAVENGER;

EID: 84990924594     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-016-2075-x     Document Type: Article
Times cited : (19)

References (49)
  • 1
    • 77953686182 scopus 로고    scopus 로고
    • Brominated flame retardants in the Arctic environment—trends and new candidates
    • PID: 19815253
    • de Wit CA, Herzke D, Vorkamp K (2010) Brominated flame retardants in the Arctic environment—trends and new candidates. Sci Total Environ 408:2885–2918
    • (2010) Sci Total Environ , vol.408 , pp. 2885-2918
    • de Wit, C.A.1    Herzke, D.2    Vorkamp, K.3
  • 2
    • 0036223196 scopus 로고    scopus 로고
    • An overview of brominated flame retardants in the environment
    • PID: 11999784
    • de Wit CA (2002) An overview of brominated flame retardants in the environment. Chemosphere 46:583–624
    • (2002) Chemosphere , vol.46 , pp. 583-624
    • de Wit, C.A.1
  • 3
    • 51949115572 scopus 로고    scopus 로고
    • Hexabromocyclododecanes and tetrabromobisphenol-A in indoor air and dust in Birmingham, UK: implications for human exposure
    • COI: 1:CAS:528:DC%2BD1cXptl2gt7c%3D, PID: 18853800
    • Abdallah MAE, Harrad S, Covaci A (2008) Hexabromocyclododecanes and tetrabromobisphenol-A in indoor air and dust in Birmingham, UK: implications for human exposure. Environ Sci Technol 42:6855–6861
    • (2008) Environ Sci Technol , vol.42 , pp. 6855-6861
    • Abdallah, M.A.E.1    Harrad, S.2    Covaci, A.3
  • 4
    • 78751617188 scopus 로고    scopus 로고
    • Tetrabromobisphenol-A, hexabromocyclododecane and its degradation products in UK human milk: relationship to external exposure
    • COI: 1:CAS:528:DC%2BC3MXhtFCjsbo%3D, PID: 21167604
    • Abdallah MA, Harrad S (2011) Tetrabromobisphenol-A, hexabromocyclododecane and its degradation products in UK human milk: relationship to external exposure. Environ Int 37:443–448
    • (2011) Environ Int , vol.37 , pp. 443-448
    • Abdallah, M.A.1    Harrad, S.2
  • 5
    • 53149130532 scopus 로고    scopus 로고
    • Exposure assessment of French women and their newborns to tetrabromobisphenol-A: occurrence measurements in maternal adipose tissue, serum, breast milk and cord serum
    • COI: 1:CAS:528:DC%2BD1cXht1SntLzL, PID: 18790516
    • Cariou R, Antignac JP, Zalko D, Berrebi A, Cravedi JP, Maume D, Marchand P, Monteau F, Riu A, Andre F, Le Bizec B (2008) Exposure assessment of French women and their newborns to tetrabromobisphenol-A: occurrence measurements in maternal adipose tissue, serum, breast milk and cord serum. Chemosphere 73:1036–1041
    • (2008) Chemosphere , vol.73 , pp. 1036-1041
    • Cariou, R.1    Antignac, J.P.2    Zalko, D.3    Berrebi, A.4    Cravedi, J.P.5    Maume, D.6    Marchand, P.7    Monteau, F.8    Riu, A.9    Andre, F.10    Le Bizec, B.11
  • 6
    • 0036229124 scopus 로고    scopus 로고
    • Exposure to polybrominated diphenyl ethers and tetrabromobisphenol A among computer technicians
    • COI: 1:CAS:528:DC%2BD38XovFWjtQ%3D%3D, PID: 11999794
    • Jakobsson K, Thuresson K, Rylander L, Sjödin A, Hagmar L, Bergman A (2002) Exposure to polybrominated diphenyl ethers and tetrabromobisphenol A among computer technicians. Chemosphere 46:709–716
    • (2002) Chemosphere , vol.46 , pp. 709-716
    • Jakobsson, K.1    Thuresson, K.2    Rylander, L.3    Sjödin, A.4    Hagmar, L.5    Bergman, A.6
  • 7
    • 33947219343 scopus 로고    scopus 로고
    • In vitro toxicity of tetrabromobisphenol-A on cerebellar granule cells: cell death, free radical formation, calcium influx and extracellular glutamate
    • COI: 1:CAS:528:DC%2BD2sXjtlCjt78%3D, PID: 17205976
    • Reistad T, Mariussen E, Ring A, Fonnum F (2007) In vitro toxicity of tetrabromobisphenol-A on cerebellar granule cells: cell death, free radical formation, calcium influx and extracellular glutamate. Toxicol Sci 96:268–278
    • (2007) Toxicol Sci , vol.96 , pp. 268-278
    • Reistad, T.1    Mariussen, E.2    Ring, A.3    Fonnum, F.4
  • 8
    • 84859242331 scopus 로고    scopus 로고
    • 2+-ATPase inhibition, beta-amyloid peptide release and apoptosis in SH-SY5Y neuronal cells
    • COI: 1:CAS:528:DC%2BC38XlsFykuro%3D, PID: 22485137
    • 2+-ATPase inhibition, beta-amyloid peptide release and apoptosis in SH-SY5Y neuronal cells. PLoS One 7(4):e33059
    • (2012) PLoS One , vol.7 , Issue.4
    • Al-Mousa, F.1    Michelangeli, F.2
  • 9
    • 84873729659 scopus 로고    scopus 로고
    • Synergistic neurotoxicity of oxygen-glucose deprivation and tetrabromobisphenolA in vitro: role of oxidative stress
    • PID: 23238473
    • Ziemińska E, Stafiej A, Toczyłowska B, Lazarewicz JW (2012) Synergistic neurotoxicity of oxygen-glucose deprivation and tetrabromobisphenolA in vitro: role of oxidative stress. Pharmacol Rep 64:1166–1178
    • (2012) Pharmacol Rep , vol.64 , pp. 1166-1178
    • Ziemińska, E.1    Stafiej, A.2    Toczyłowska, B.3    Lazarewicz, J.W.4
  • 10
    • 84940896861 scopus 로고    scopus 로고
    • Role of ryanodine and NMDA receptors in tetrabromobisphenol A-induced calcium imbalance and cytotoxicity in primary cultures of rat cerebellar granule cells
    • COI: 1:CAS:528:DC%2BC2MXht1elu7fN, PID: 26215658
    • Zieminska E, Stafiej A, Toczylowska B, Albrecht J, Lazarewicz JW (2015) Role of ryanodine and NMDA receptors in tetrabromobisphenol A-induced calcium imbalance and cytotoxicity in primary cultures of rat cerebellar granule cells. Neurotox Res 28:195–208
    • (2015) Neurotox Res , vol.28 , pp. 195-208
    • Zieminska, E.1    Stafiej, A.2    Toczylowska, B.3    Albrecht, J.4    Lazarewicz, J.W.5
  • 11
    • 84896052759 scopus 로고    scopus 로고
    • PPAR-γ agonist GW1929 but not antagonist GW9662 reduces TBBPA-induced neurotoxicity in primary neocortical cells
    • COI: 1:CAS:528:DC%2BC2cXjsFGns7k%3D, PID: 24132472
    • Wojtowicz AK, Szychowski KA, Kajta M (2014) PPAR-γ agonist GW1929 but not antagonist GW9662 reduces TBBPA-induced neurotoxicity in primary neocortical cells. Neurotox Res 25:311–322
    • (2014) Neurotox Res , vol.25 , pp. 311-322
    • Wojtowicz, A.K.1    Szychowski, K.A.2    Kajta, M.3
  • 12
    • 84921531543 scopus 로고    scopus 로고
    • A reproductive, developmental and neurobehavioral study following oral exposure of tetrabromobisphenol A on Sprague–Dawley rats
    • COI: 1:CAS:528:DC%2BC2MXltVekuw%3D%3D, PID: 25523853
    • Cope RB, Kacew S, Dourson M (2015) A reproductive, developmental and neurobehavioral study following oral exposure of tetrabromobisphenol A on Sprague–Dawley rats. Toxicology 329:49–59
    • (2015) Toxicology , vol.329 , pp. 49-59
    • Cope, R.B.1    Kacew, S.2    Dourson, M.3
  • 13
    • 77954094899 scopus 로고    scopus 로고
    • The potential of selected brominated flame retardants to affect neurological development
    • COI: 1:CAS:528:DC%2BC3cXotVantb0%3D, PID: 20582854
    • Williams AL, DeSesso JM (2010) The potential of selected brominated flame retardants to affect neurological development. J Toxicol Environ Health B Crit Rev 13:411–448
    • (2010) J Toxicol Environ Health B Crit Rev , vol.13 , pp. 411-448
    • Williams, A.L.1    DeSesso, J.M.2
  • 14
    • 67349284347 scopus 로고    scopus 로고
    • Neurobehavioral effects of tetrabromobisphenol A, a brominated flame retardant, in mice
    • COI: 1:CAS:528:DC%2BD1MXnsFygsb4%3D, PID: 19463927
    • Nakajima A, Saigusa D, Tetsu N, Yamakuni T, Tomioka Y, Hishinuma T (2009) Neurobehavioral effects of tetrabromobisphenol A, a brominated flame retardant, in mice. Toxicol Lett 189:78–83
    • (2009) Toxicol Lett , vol.189 , pp. 78-83
    • Nakajima, A.1    Saigusa, D.2    Tetsu, N.3    Yamakuni, T.4    Tomioka, Y.5    Hishinuma, T.6
  • 15
    • 84864128675 scopus 로고    scopus 로고
    • Multiple novel modes of action involved in the in vitro neurotoxic effects of tetrabromobisphenol-A
    • COI: 1:CAS:528:DC%2BC38XhtVShurjM, PID: 22547355
    • Hendriks HS, van Kleef RG, van den Berg M, Westerink RH (2012) Multiple novel modes of action involved in the in vitro neurotoxic effects of tetrabromobisphenol-A. Toxicol Sci 128:235–246
    • (2012) Toxicol Sci , vol.128 , pp. 235-246
    • Hendriks, H.S.1    van Kleef, R.G.2    van den Berg, M.3    Westerink, R.H.4
  • 17
    • 84897113604 scopus 로고    scopus 로고
    • A comparison of the in vitro cyto- and neurotoxicity of brominated and halogen-free flame retardants: prioritization in search for safe(r) alternatives
    • COI: 1:CAS:528:DC%2BC2cXisl2lsA%3D%3D, PID: 24395120
    • Hendriks HS, Meijer M, MuilwijkM, van den Berg M, Westerink RH (2014) A comparison of the in vitro cyto- and neurotoxicity of brominated and halogen-free flame retardants: prioritization in search for safe(r) alternatives. Arch Toxicol 88:857–869
    • (2014) Arch Toxicol , vol.88 , pp. 857-869
    • Hendriks, H.S.1    Meijer, M.2    Muilwijk, M.3    van den Berg, M.4    Westerink, R.H.5
  • 20
    • 34447323577 scopus 로고    scopus 로고
    • Biotransformation and cytotoxicity of a brominated flame retardant, tetrabromobisphenol A, and its analogues in rat hepatocytes
    • COI: 1:CAS:528:DC%2BD2sXnsV2jtLg%3D, PID: 17620216
    • Nakagawa Y, Suzuki T, Ishii H, Ogata A (2007) Biotransformation and cytotoxicity of a brominated flame retardant, tetrabromobisphenol A, and its analogues in rat hepatocytes. Xenobiotica 37:693–708
    • (2007) Xenobiotica , vol.37 , pp. 693-708
    • Nakagawa, Y.1    Suzuki, T.2    Ishii, H.3    Ogata, A.4
  • 21
    • 3342910554 scopus 로고    scopus 로고
    • Mitochondrial calcium and oxidative stress as mediators of ischemic brain injury
    • COI: 1:CAS:528:DC%2BD2cXlvVWitbk%3D, PID: 15261481
    • Starkov AA, Chinopoulos C, Fiskum G (2004) Mitochondrial calcium and oxidative stress as mediators of ischemic brain injury. Cell Calcium 36:257–264
    • (2004) Cell Calcium , vol.36 , pp. 257-264
    • Starkov, A.A.1    Chinopoulos, C.2    Fiskum, G.3
  • 22
    • 84939795261 scopus 로고    scopus 로고
    • Researching glutamate: induced cytotoxicity in different cell lines: a comparative/collective analysis/study
    • PID: 25852482
    • Kritis AA, Stamoula EG, Paniskaki KA, Vavilis TD (2015) Researching glutamate: induced cytotoxicity in different cell lines: a comparative/collective analysis/study. Front Cell Neurosci. doi:10.3389/fncel.2015.00091.
    • (2015) Front Cell Neurosci
    • Kritis, A.A.1    Stamoula, E.G.2    Paniskaki, K.A.3    Vavilis, T.D.4
  • 23
    • 70450216122 scopus 로고    scopus 로고
    • Mechanisms involved in the neurotoxic effects of environmental toxicants such as polychlorinated biphenyls and brominated flame retardants
    • COI: 1:CAS:528:DC%2BD1MXhsFGqtrvL, PID: 19818104
    • Fonnum F, Mariussen E (2009) Mechanisms involved in the neurotoxic effects of environmental toxicants such as polychlorinated biphenyls and brominated flame retardants. J Neurochem 111:1327–1347
    • (2009) J Neurochem , vol.111 , pp. 1327-1347
    • Fonnum, F.1    Mariussen, E.2
  • 24
    • 0026712316 scopus 로고
    • Pharmacological and functional characterization of excitatory amino acid mediated cytotoxicity in cerebral cortical neurons
    • COI: 1:CAS:528:DyaK3sXhtFKrtrw%3D, PID: 1332807
    • Schousboe A, Frandsen A, Krogsgaard-Larsen P (1992) Pharmacological and functional characterization of excitatory amino acid mediated cytotoxicity in cerebral cortical neurons. Cell Biol Toxicol 8:93–100
    • (1992) Cell Biol Toxicol , vol.8 , pp. 93-100
    • Schousboe, A.1    Frandsen, A.2    Krogsgaard-Larsen, P.3
  • 25
    • 33750693109 scopus 로고    scopus 로고
    • (+/–)-2-Chloropropionic acid elevates reactive oxygen species formation in human neutrophil granulocytes
    • COI: 1:CAS:528:DC%2BD28Xht1Shu7bL, PID: 17007989
    • Aam BB, Fonnum F (2006) (+/–)-2-Chloropropionic acid elevates reactive oxygen species formation in human neutrophil granulocytes. Toxicology 228:124–134
    • (2006) Toxicology , vol.228 , pp. 124-134
    • Aam, B.B.1    Fonnum, F.2
  • 27
    • 77957262510 scopus 로고    scopus 로고
    • Low molecular weight thiols reduce thimerosal neurotoxicity in vitro: modulation by proteins
    • COI: 1:CAS:528:DC%2BC3cXht1CgurvE, PID: 20696200
    • Zieminska E, Toczylowska B, Stafiej A, Lazarewicz JW (2010) Low molecular weight thiols reduce thimerosal neurotoxicity in vitro: modulation by proteins. Toxicology 276:154–163
    • (2010) Toxicology , vol.276 , pp. 154-163
    • Zieminska, E.1    Toczylowska, B.2    Stafiej, A.3    Lazarewicz, J.W.4
  • 28
    • 0023692586 scopus 로고
    • A spectrophotometric method for determination of catalase activity in small tissue samples
    • COI: 1:CAS:528:DyaL1MXjtlCk, PID: 3064653
    • Johansson LH, Borg LA (1988) A spectrophotometric method for determination of catalase activity in small tissue samples. Anal Biochem 174:331–336
    • (1988) Anal Biochem , vol.174 , pp. 331-336
    • Johansson, L.H.1    Borg, L.A.2
  • 29
    • 0028793257 scopus 로고
    • Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function
    • COI: 1:CAS:528:DyaK2MXptV2gsLc%3D, PID: 7576644
    • Ankarcrona M, Dypbukt JM, Bonfoco E, Zhivotovsky B, Orrenius S, Lipton SA, Nicotera P (1995) Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron 15:961–973
    • (1995) Neuron , vol.15 , pp. 961-973
    • Ankarcrona, M.1    Dypbukt, J.M.2    Bonfoco, E.3    Zhivotovsky, B.4    Orrenius, S.5    Lipton, S.A.6    Nicotera, P.7
  • 30
    • 33845988785 scopus 로고    scopus 로고
    • Beneficial effect of antioxidants in purified neurons derived from rat cortical culture
    • COI: 1:CAS:528:DC%2BD2sXls1Slsw%3D%3D, PID: 17157828
    • Sagara J, Fujiwara K, Sakakura Y, Sato H, Bannai S, Makino N (2007) Beneficial effect of antioxidants in purified neurons derived from rat cortical culture. Brain Res 1131:11–16
    • (2007) Brain Res , vol.1131 , pp. 11-16
    • Sagara, J.1    Fujiwara, K.2    Sakakura, Y.3    Sato, H.4    Bannai, S.5    Makino, N.6
  • 31
    • 33645845744 scopus 로고    scopus 로고
    • Excitotoxic neuronal injury in acute homocysteine neurotoxicity: role of calcium and mitochondrial alterations
    • COI: 1:CAS:528:DC%2BD28XjtFCrsbg%3D, PID: 16513213
    • Zieminska E, Matyja E, Kozlowska H, Stafiej A, Lazarewicz JW (2006) Excitotoxic neuronal injury in acute homocysteine neurotoxicity: role of calcium and mitochondrial alterations. Neurochem Int 48:491–497
    • (2006) Neurochem Int , vol.48 , pp. 491-497
    • Zieminska, E.1    Matyja, E.2    Kozlowska, H.3    Stafiej, A.4    Lazarewicz, J.W.5
  • 32
    • 33746081243 scopus 로고    scopus 로고
    • Cyclosporin A increases mitochondrial calcium uptake capacity in cortical astrocytes but not cerebellar granule neurons
    • COI: 1:CAS:528:DC%2BD28XmvFeitro%3D, PID: 16786428
    • Bambrick LL, Chandrasekaran K, Mehrabian Z, Wright C, Krueger BK, Fiskum G (2006) Cyclosporin A increases mitochondrial calcium uptake capacity in cortical astrocytes but not cerebellar granule neurons. J Bioenerg Biomembr 38:43–47
    • (2006) J Bioenerg Biomembr , vol.38 , pp. 43-47
    • Bambrick, L.L.1    Chandrasekaran, K.2    Mehrabian, Z.3    Wright, C.4    Krueger, B.K.5    Fiskum, G.6
  • 33
    • 79960841058 scopus 로고    scopus 로고
    • Caveats and limitations of plate reader-based high-throughput kinetic measurements of intracellular calcium levels
    • COI: 1:CAS:528:DC%2BC3MXpsFKgsLk%3D, PID: 21684299
    • Heusinkveld HJ, Westerink RH (2011) Caveats and limitations of plate reader-based high-throughput kinetic measurements of intracellular calcium levels. Toxicol Appl Pharmacol 255:1–8
    • (2011) Toxicol Appl Pharmacol , vol.255 , pp. 1-8
    • Heusinkveld, H.J.1    Westerink, R.H.2
  • 34
    • 84907934570 scopus 로고    scopus 로고
    • Comparison of plate reader-based methods with fluorescence microscopy for measurements of intracellular calcium levels for the assessment of in vitro neurotoxicity
    • COI: 1:CAS:528:DC%2BC2cXhs1Squr%2FL, PID: 25224521
    • Meijer M, Hendriks HS, Heusinkveld HJ, Langeveld WT, Westerink RH (2014) Comparison of plate reader-based methods with fluorescence microscopy for measurements of intracellular calcium levels for the assessment of in vitro neurotoxicity. Neurotoxicology 45:31–37
    • (2014) Neurotoxicology , vol.45 , pp. 31-37
    • Meijer, M.1    Hendriks, H.S.2    Heusinkveld, H.J.3    Langeveld, W.T.4    Westerink, R.H.5
  • 35
    • 84875271952 scopus 로고    scopus 로고
    • Troubleshooting the dichlorofluorescein assay to avoid artifacts in measurement of toxicant-stimulated cellular production of reactive oxidant species
    • COI: 1:CAS:528:DC%2BC3sXjtFWnt74%3D, PID: 23380227
    • Tetz LM, Kamau PW, Cheng AA, Meeker JD, Loch-Caruso R (2013) Troubleshooting the dichlorofluorescein assay to avoid artifacts in measurement of toxicant-stimulated cellular production of reactive oxidant species. J Pharmacol Toxicol Methods 67:56–60
    • (2013) J Pharmacol Toxicol Methods , vol.67 , pp. 56-60
    • Tetz, L.M.1    Kamau, P.W.2    Cheng, A.A.3    Meeker, J.D.4    Loch-Caruso, R.5
  • 36
    • 84944128304 scopus 로고    scopus 로고
    • TBBPA causes neurotoxic and the apoptotic responses in cultured mouse hippocampal neurons in vitro
    • COI: 1:CAS:528:DC%2BC28XmslKrsb4%3D, PID: 26721346
    • Szychowski KA, Wójtowicz AK (2016) TBBPA causes neurotoxic and the apoptotic responses in cultured mouse hippocampal neurons in vitro. Pharmacol Rep 68:20–26
    • (2016) Pharmacol Rep , vol.68 , pp. 20-26
    • Szychowski, K.A.1    Wójtowicz, A.K.2
  • 37
    • 84961124428 scopus 로고    scopus 로고
    • Tetrabromobisphenol A (TBBPA)-stimulated reactive oxygen species (ROS) production in cell-free model using the 2′,7′-dichlorodihydrofluorescein diacetate (H2DCFDA) assay-limitations of method
    • PID: 26976009
    • Szychowski KA, Rybczyńska-Tkaczyk K, Leja ML, Wójtowicz AK, Gmiński J (2016) Tetrabromobisphenol A (TBBPA)-stimulated reactive oxygen species (ROS) production in cell-free model using the 2′,7′-dichlorodihydrofluorescein diacetate (H2DCFDA) assay-limitations of method. Environ Sci Pollut Res Int 23:12246–12252
    • (2016) Environ Sci Pollut Res Int , vol.23 , pp. 12246-12252
    • Szychowski, K.A.1    Rybczyńska-Tkaczyk, K.2    Leja, M.L.3    Wójtowicz, A.K.4    Gmiński, J.5
  • 39
    • 84930952984 scopus 로고    scopus 로고
    • Changes in the mitochondrial antioxidant systems in neurodegenerative diseases and acute brain disorders
    • COI: 1:CAS:528:DC%2BC2MXntVersg%3D%3D, PID: 25576182
    • Ruszkiewicz J, Albrecht J (2015) Changes in the mitochondrial antioxidant systems in neurodegenerative diseases and acute brain disorders. Neurochem Int 88:66–72
    • (2015) Neurochem Int , vol.88 , pp. 66-72
    • Ruszkiewicz, J.1    Albrecht, J.2
  • 40
    • 84938514349 scopus 로고    scopus 로고
    • Acute and chronic toxicity of tetrabromobisphenol A to three aquatic species under different pH conditions
    • COI: 1:CAS:528:DC%2BC2MXnvF2ku7o%3D, PID: 25980965
    • He Q, Wang X, Sun P, Wang Z, Wang L (2015) Acute and chronic toxicity of tetrabromobisphenol A to three aquatic species under different pH conditions. Aquat Toxicol 164:145–154
    • (2015) Aquat Toxicol , vol.164 , pp. 145-154
    • He, Q.1    Wang, X.2    Sun, P.3    Wang, Z.4    Wang, L.5
  • 41
    • 84861309322 scopus 로고    scopus 로고
    • Therapeutic potential of targeting hydrogen peroxide metabolism in the treatment of brain ischaemia
    • COI: 1:CAS:528:DC%2BC38XotlWmtrY%3D, PID: 22352897
    • Armogida M, Nisticò R, Mercuri NB (2012) Therapeutic potential of targeting hydrogen peroxide metabolism in the treatment of brain ischaemia. Br J Pharmacol 166:1211–1224
    • (2012) Br J Pharmacol , vol.166 , pp. 1211-1224
    • Armogida, M.1    Nisticò, R.2    Mercuri, N.B.3
  • 42
    • 12344290339 scopus 로고    scopus 로고
    • The effect of a brominated flame retardant, tetrabromobisphenol-A, on free radical formation in human neutrophil granulocytes: the involvement of the MAP kinase pathway and protein kinase C
    • COI: 1:CAS:528:DC%2BD2cXhtVOjsrbE, PID: 15456914
    • Reistad T, Mariussen E, Fonnum F (2005) The effect of a brominated flame retardant, tetrabromobisphenol-A, on free radical formation in human neutrophil granulocytes: the involvement of the MAP kinase pathway and protein kinase C. Toxicol Sci 83:89–100
    • (2005) Toxicol Sci , vol.83 , pp. 89-100
    • Reistad, T.1    Mariussen, E.2    Fonnum, F.3
  • 43
    • 77956223101 scopus 로고    scopus 로고
    • Calcium and mitochondrial reactive oxygen species generation: how to read the facts
    • PID: 20421693
    • Adam-Vizi V, Starkov AA (2010) Calcium and mitochondrial reactive oxygen species generation: how to read the facts. J Alzheimers Dis 20(Suppl 2):S413–S426
    • (2010) J Alzheimers Dis , vol.20 , pp. S413-S426
    • Adam-Vizi, V.1    Starkov, A.A.2
  • 44
    • 79952405292 scopus 로고    scopus 로고
    • Neuronal calcium homeostasis and dysregulation
    • COI: 1:CAS:528:DC%2BC3MXivVGjt70%3D, PID: 20626318
    • Gleichmann M, Mattson MP (2011) Neuronal calcium homeostasis and dysregulation. Antioxid Redox Signal 14:1261–1273
    • (2011) Antioxid Redox Signal , vol.14 , pp. 1261-1273
    • Gleichmann, M.1    Mattson, M.P.2
  • 45
    • 0037727699 scopus 로고    scopus 로고
    • The effect of brominated flame retardants on neurotransmitter uptake into rat brain synaptosomes and vesicles
    • COI: 1:CAS:528:DC%2BD3sXjsVGnuro%3D, PID: 12742101
    • Mariussen E, Fonnum F (2003) The effect of brominated flame retardants on neurotransmitter uptake into rat brain synaptosomes and vesicles. Neurochem Int 43:533–542
    • (2003) Neurochem Int , vol.43 , pp. 533-542
    • Mariussen, E.1    Fonnum, F.2
  • 46
    • 84876777712 scopus 로고    scopus 로고
    • Physiologic functions of cyclophilin D and the mitochondrial permeability transition pore
    • COI: 1:CAS:528:DC%2BC3sXotFyktLY%3D, PID: 23538482
    • Elrod JW, Molkentin JD (2013) Physiologic functions of cyclophilin D and the mitochondrial permeability transition pore. Circ J 77:1111–1122
    • (2013) Circ J , vol.77 , pp. 1111-1122
    • Elrod, J.W.1    Molkentin, J.D.2
  • 47
    • 0034668844 scopus 로고    scopus 로고
    • Limitations of cyclosporin A inhibition of the permeability transition in CNS mitochondria
    • COI: 1:CAS:528:DC%2BD3cXot1Grtbk%3D, PID: 11069928
    • Brustovetsky N, Dubinsky JM (2000) Limitations of cyclosporin A inhibition of the permeability transition in CNS mitochondria. J Neurosci 20:8229–8237
    • (2000) J Neurosci , vol.20 , pp. 8229-8237
    • Brustovetsky, N.1    Dubinsky, J.M.2
  • 48
    • 0141728479 scopus 로고    scopus 로고
    • Molecular actions of calcineurin inhibitors
    • COI: 1:CAS:528:DC%2BD3sXot1CgtrY%3D, PID: 12942158
    • Hamawy MM (2003) Molecular actions of calcineurin inhibitors. Drug News Perspect 16:277–282
    • (2003) Drug News Perspect , vol.16 , pp. 277-282
    • Hamawy, M.M.1
  • 49
    • 77953495143 scopus 로고    scopus 로고
    • Calcineurin inhibition enhances motor neuron survival following injury
    • COI: 1:CAS:528:DC%2BC3cXns1ykt74%3D, PID: 19243469
    • Hui KK, Liadis N, Robertson J, Kanungo A, Henderson JT (2010) Calcineurin inhibition enhances motor neuron survival following injury. J Cell Mol Med 14:671–686
    • (2010) J Cell Mol Med , vol.14 , pp. 671-686
    • Hui, K.K.1    Liadis, N.2    Robertson, J.3    Kanungo, A.4    Henderson, J.T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.