Comparison of plate reader-based methods with fluorescence microscopy for measurements of intracellular calcium levels for the assessment of in vitro neurotoxicity

NeuroToxicology

Volumn 45, Issue , 2014, Pages 31-37

  Meijer, Marieke ^a   Hendriks, Hester S ^a   Heusinkveld, Harm J ^a,b   Langeveld, Wendy T ^a   Westerink, Remco H S ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b IUF LEIBNIZ RESEARCH INSTITUTE FOR ENVIRONMENTAL MEDICINE   (Germany)

Author keywords

Chemical screening methods; Fluorescence microscopy; High throughput testing strategies; In vitro neurotoxicity; Intracellular calcium concentration ( Ca2+ i); Plate reader

Indexed keywords

CALCIUM; DIELDRIN; LINDANE; POLYCHLORINATED BIPHENYL; TETRABROMOBISPHENOL A; NEUROTOXIN; POLLUTANT; POLYBROMINATED BIPHENYL;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CHEMICAL ANALYSIS; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEPOLARIZATION; FLUORESCENCE MICROSCOPY; IN VITRO STUDY; MICROPLATE READER; NEUROTOXICITY; NONHUMAN; POLLUTANT; RAT; ANIMAL; HIGH THROUGHPUT SCREENING; KINETICS; METABOLISM; PC12 CELL LINE; PROCEDURES; REPRODUCIBILITY; TOXICITY;

ANIMALS; CALCIUM; DIELDRIN; ENVIRONMENTAL POLLUTANTS; HIGH-THROUGHPUT SCREENING ASSAYS; KINETICS; LINDANE; MICROSCOPY, FLUORESCENCE; NEUROTOXINS; PC12 CELLS; POLYBROMINATED BIPHENYLS; POLYCHLORINATED BIPHENYLS; RATS; REPRODUCIBILITY OF RESULTS;

EID: 84907934570     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2014.09.001     Document Type: Article

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