A comparison of the in vitro cyto- and neurotoxicity of brominated and halogen-free flame retardants: Prioritization in search for safe(r) alternatives

Archives of Toxicology

Volumn 88, Issue 4, 2014, Pages 857-869

  Hendriks, Hester S ^a   Meijer, Marieke ^a   Muilwijk, Mirthe ^a   Van Den Berg, Martin ^a   Westerink, Remco H S ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Brominated flame retardants (BFRs); Halogen free flame retardants (HFFRs); In vitro neurotoxicology; Prioritization; Risk assessment; Substitution of BFRs

Indexed keywords

9,10 DIHYDRO 9 OXA 10 PHOSPHAPHENANTHRENE 10 OXIDE; ALUMINUM TRIHYDROXIDE; AMMONIA; BROMINATED FLAME RETARDANT; BROMINE; CALCIUM ION; DECABROMODIPHENYL ETHER; FLAME RETARDANT; HALOGEN; HALOGEN FREE FLAME RETARDANT; MAGNESIUM HYDROXIDE; MELAMINE POLYPHOSPHATE; MONTMORILLONITE; REACTIVE OXYGEN METABOLITE; RESORCINOL BIS(DIPHENYLPHOSPHATE); TRIPHENYL PHOSPHATE; UNCLASSIFIED DRUG; ZINC DERIVATIVE; ZINC HYDROXYSTANNATE; ZINC STANNATE; CALCIUM; CALCIUM CHANNEL; POLLUTANT;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CELL ASSAY; CELL VIABILITY; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXICITY; FLUORESCENCE IMAGING; IN VITRO STUDY; NERVE CELL MEMBRANE STEADY POTENTIAL; NEUROBLASTOMA CELL; NEUROTOXICITY; NONHUMAN; PC12 CELL; PRIORITY JOURNAL; RAT; RISK ASSESSMENT; TOXICITY TESTING; ANIMAL; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; HEALTH CARE PLANNING; MEDICAL RESEARCH; METABOLISM; NERVE CELL; NEUROTOXICITY SYNDROMES; OXIDATIVE STRESS; PATHOLOGY; PC12 CELL LINE; POLLUTANT; PROCEDURES; TIME FACTOR; TOXICITY;

ANIMALS; BIOMEDICAL RESEARCH; CALCIUM; CALCIUM CHANNELS; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; FLAME RETARDANTS; HEALTH PRIORITIES; NEURONS; NEUROTOXICITY SYNDROMES; OXIDATIVE STRESS; PC12 CELLS; RATS; REACTIVE OXYGEN SPECIES; RISK ASSESSMENT; TIME FACTORS; TOXICITY TESTS;

EID: 84897113604     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-013-1187-1     Document Type: Article

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