Widespread Shortening of 3’ Untranslated Regions and Increased Exon Inclusion Are Evolutionarily Conserved Features of Innate Immune Responses to Infection

PLoS Genetics

Volumn 12, Issue 9, 2016, Pages

  Pai, Athma A ^a   Baharian, Golshid ^b,c   Pagé Sabourin, Ariane ^c   Brinkworth, Jessica F ^b,c,d   Nédélec, Yohann ^b,c   Foley, Joseph W ^e   Grenier, Jean Christophe ^c   Siddle, Katherine J ^f   Dumaine, Anne ^c   Yotova, Vania ^c   Johnson, Zachary P ^g,h   Lanford, Robert E ⁱ   Burge, Christopher B ^a,j   Barreiro, Luis B ^b,c  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c UNIVERSITY OF MONTREAL   (Canada)

^d UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^e STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f HARVARD UNIVERSITY   (United States)

^g EMORY UNIVERSITY   (United States)

^h EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁱ SOUTHWEST NATIONAL PRIMATE RESEARCH CENTER   (United States)

^j Massachusetts Institute of Technology Cambridge   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; INTERLEUKIN 1BETA; INTERLEUKIN 20; INTERLEUKIN 24; INTERLEUKIN 7; MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE;

3' UNTRANSLATED REGION; ADULT; ALTERNATIVE RNA SPLICING; ARTICLE; BACTERIAL INFECTION; CONTROLLED STUDY; DOWN REGULATION; EXON; GENE CASSETTE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC CONSERVATION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; INNATE IMMUNITY; INTRON; LISTERIA MONOCYTOGENES; MACROPHAGE; MALE; NONHUMAN; RNA PROCESSING; RNA SEQUENCE; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM; SIGNAL TRANSDUCTION; UPREGULATION;

EID: 84990232899     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1006338     Document Type: Article

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