메뉴 건너뛰기




Volumn 33, Issue 19, 2016, Pages 1732-1750

Microglial/Macrophage Polarization Dynamics following Traumatic Brain Injury

Author keywords

M1 like; M2 like; microglia macrophage; NOX2, polarization; traumatic brain injury

Indexed keywords

ENZYME INHIBITOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2;

EID: 84990026708     PISSN: 08977151     EISSN: 15579042     Source Type: Journal    
DOI: 10.1089/neu.2015.4268     Document Type: Article
Times cited : (240)

References (52)
  • 2
    • 84886688737 scopus 로고    scopus 로고
    • Phenotypic transitions of macrophages orchestrate tissue repair
    • Novak, M.L. and Koh, T.J. (2013). Phenotypic transitions of macrophages orchestrate tissue repair. Am. J. Pathol. 183, 1352-1363.
    • (2013) Am. J. Pathol. , vol.183 , pp. 1352-1363
    • Novak, M.L.1    Koh, T.J.2
  • 4
    • 70449526190 scopus 로고    scopus 로고
    • Heterogeneity of microglial activation in the innate immune response in the brain
    • Colton, C.A. (2009). Heterogeneity of microglial activation in the innate immune response in the brain. J. Neuroimmune Pharmacol. 4, 399-418.
    • (2009) J. Neuroimmune Pharmacol. , vol.4 , pp. 399-418
    • Colton, C.A.1
  • 5
    • 84902549638 scopus 로고    scopus 로고
    • Neuroinflammation and M2 microglia: The good, the bad, and the inflamed
    • Cherry, J.D., Olschowka, J.A., and O'Banion, M.K. (2014). Neuroinflammation and M2 microglia: the good, the bad, and the inflamed. J. Neuroinflammation 11, 98.
    • (2014) J. Neuroinflammation , vol.11 , pp. 98
    • Cherry, J.D.1    Olschowka, J.A.2    O'Banion, M.K.3
  • 6
    • 84871896555 scopus 로고    scopus 로고
    • Long-term upregulation of inflammation and suppression of cell proliferation in the brain of adult rats exposed to traumatic brain injury using the controlled cortical impact model
    • Acosta, S.A., Tajiri, N., Shinozuka, K., Ishikawa, H., Grimmig, B., Diamond, D., Sanberg, P.R., Bickford, P.C., Kaneko, Y., and Borlongan, C.V. (2013). Long-term upregulation of inflammation and suppression of cell proliferation in the brain of adult rats exposed to traumatic brain injury using the controlled cortical impact model. PLoS One 8, e53376.
    • (2013) PLoS One , vol.8 , pp. e53376
    • Acosta, S.A.1    Tajiri, N.2    Shinozuka, K.3    Ishikawa, H.4    Grimmig, B.5    Diamond, D.6    Sanberg, P.R.7    Bickford, P.C.8    Kaneko, Y.9    Borlongan, C.V.10
  • 7
    • 84903774276 scopus 로고    scopus 로고
    • Repeated mild traumatic brain injury causes chronic neuroinflammation, changes in hippocampal synaptic plasticity, and associated cognitive deficits
    • Aungst, S.L., Kabadi, S.V., Thompson, S.M., Stoica, B.A., and Faden, A.I. (2014). Repeated mild traumatic brain injury causes chronic neuroinflammation, changes in hippocampal synaptic plasticity, and associated cognitive deficits. J. Cereb. Blood Flow Metab. 34, 1223-1232.
    • (2014) J. Cereb. Blood Flow Metab. , vol.34 , pp. 1223-1232
    • Aungst, S.L.1    Kabadi, S.V.2    Thompson, S.M.3    Stoica, B.A.4    Faden, A.I.5
  • 8
    • 84873397447 scopus 로고    scopus 로고
    • Inflammation and white matter degeneration persist for years after a single traumatic brain injury
    • Johnson, V.E., Stewart, J.E., Begbie, F.D., Trojanowski, J.Q., Smith, D.H., and Stewart, W. (2013). Inflammation and white matter degeneration persist for years after a single traumatic brain injury. Brain 136, 28-42.
    • (2013) Brain , vol.136 , pp. 28-42
    • Johnson, V.E.1    Stewart, J.E.2    Begbie, F.D.3    Trojanowski, J.Q.4    Smith, D.H.5    Stewart, W.6
  • 9
    • 84891827843 scopus 로고    scopus 로고
    • Progressive neurodegeneration after experimental brain trauma: Association with chronic microglial activation
    • Loane, D.J., Kumar, A., Stoica, B.A., Cabatbat, R., and Faden, A.I. (2014). Progressive neurodegeneration after experimental brain trauma: association with chronic microglial activation. J. Neuropathol. Exp. Neurol. 73, 14-29.
    • (2014) J. Neuropathol. Exp. Neurol. , vol.73 , pp. 14-29
    • Loane, D.J.1    Kumar, A.2    Stoica, B.A.3    Cabatbat, R.4    Faden, A.I.5
  • 11
    • 39449125357 scopus 로고    scopus 로고
    • Prolonged microgliosis in the rhesus monkey central nervous system after traumatic brain injury
    • Nagamoto-Combs, K., McNeal, D.W., Morecraft, R.J., and Combs, C.K. (2007). Prolonged microgliosis in the rhesus monkey central nervous system after traumatic brain injury. J. Neurotrauma 24, 1719-1742.
    • (2007) J. Neurotrauma , vol.24 , pp. 1719-1742
    • Nagamoto-Combs, K.1    McNeal, D.W.2    Morecraft, R.J.3    Combs, C.K.4
  • 15
    • 84866685568 scopus 로고    scopus 로고
    • Relationship of nitric oxide synthase induction to peroxynitrite-mediated oxidative damage during the first week after experimental traumatic brain injury
    • Hall, E.D., Wang, J.A., and Miller, D.M. (2012). Relationship of nitric oxide synthase induction to peroxynitrite-mediated oxidative damage during the first week after experimental traumatic brain injury. Exp. Neurol. 238, 176-182.
    • (2012) Exp. Neurol. , vol.238 , pp. 176-182
    • Hall, E.D.1    Wang, J.A.2    Miller, D.M.3
  • 17
    • 70350558453 scopus 로고    scopus 로고
    • Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord
    • Kigerl, K.A., Gensel, J.C., Ankeny, D.P., Alexander, J.K., Donnelly, D.J., and Popovich, P.G. (2009). Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord. J. Neurosci. 29, 13435-13444.
    • (2009) J. Neurosci. , vol.29 , pp. 13435-13444
    • Kigerl, K.A.1    Gensel, J.C.2    Ankeny, D.P.3    Alexander, J.K.4    Donnelly, D.J.5    Popovich, P.G.6
  • 19
    • 0035980160 scopus 로고    scopus 로고
    • Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O(2)(-) and systolic blood pressure in mice
    • Rey, F.E., Cifuentes, M.E., Kiarash, A., Quinn, M.T., and Pagano, P.J. (2001). Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O(2)(-) and systolic blood pressure in mice. Circ. Res. 89, 408-414.
    • (2001) Circ. Res. , vol.89 , pp. 408-414
    • Rey, F.E.1    Cifuentes, M.E.2    Kiarash, A.3    Quinn, M.T.4    Pagano, P.J.5
  • 21
    • 84875730240 scopus 로고    scopus 로고
    • NADPH oxidase-mediated triggering of inflammasome activation in mouse podocytes and glomeruli during hyperhomocysteinemia
    • Abais, J.M., Zhang, C., Xia, M., Liu, Q., Gehr, T.W., Boini, K.M., and Li, P.L. (2013). NADPH oxidase-mediated triggering of inflammasome activation in mouse podocytes and glomeruli during hyperhomocysteinemia. Antioxid. Redox Signal. 18, 1537-1548.
    • (2013) Antioxid. Redox Signal. , vol.18 , pp. 1537-1548
    • Abais, J.M.1    Zhang, C.2    Xia, M.3    Liu, Q.4    Gehr, T.W.5    Boini, K.M.6    Li, P.L.7
  • 22
    • 48249146633 scopus 로고    scopus 로고
    • Dynamics of the inflammatory response after murine spinal cord injury revealed by flow cytometry
    • Stirling, D.P. and Yong, V.W. (2008). Dynamics of the inflammatory response after murine spinal cord injury revealed by flow cytometry. J. Neurosci. Res. 86, 1944-1958.
    • (2008) J. Neurosci. Res. , vol.86 , pp. 1944-1958
    • Stirling, D.P.1    Yong, V.W.2
  • 24
    • 84873452455 scopus 로고    scopus 로고
    • Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states
    • Kumar, A., Stoica, B.A., Sabirzhanov, B., Burns, M.P., Faden, A.I., and Loane, D.J. (2013). Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states. Neurobiol. Aging 34, 1397-1411.
    • (2013) Neurobiol. Aging , vol.34 , pp. 1397-1411
    • Kumar, A.1    Stoica, B.A.2    Sabirzhanov, B.3    Burns, M.P.4    Faden, A.I.5    Loane, D.J.6
  • 26
    • 84855360054 scopus 로고    scopus 로고
    • Selective CDK inhibitor limits neuroinflammation and progressive neurodegeneration after brain trauma
    • Kabadi, S.V., Stoica, B.A., Byrnes, K.R., Hanscom, M., Loane, D.J., and Faden, A.I. (2012). Selective CDK inhibitor limits neuroinflammation and progressive neurodegeneration after brain trauma. J. Cereb. Blood Flow Metab. 32, 137-149.
    • (2012) J. Cereb. Blood Flow Metab. , vol.32 , pp. 137-149
    • Kabadi, S.V.1    Stoica, B.A.2    Byrnes, K.R.3    Hanscom, M.4    Loane, D.J.5    Faden, A.I.6
  • 27
    • 84899953493 scopus 로고    scopus 로고
    • Macrophagic and microglial responses after focal traumatic brain injury in the female rat
    • Turtzo, L.C., Lescher, J., Janes, L., Dean, D.D., Budde, M.D., and Frank, J.A. (2014). Macrophagic and microglial responses after focal traumatic brain injury in the female rat. J. Neuroinflammation 11, 82.
    • (2014) J. Neuroinflammation , vol.11 , pp. 82
    • Turtzo, L.C.1    Lescher, J.2    Janes, L.3    Dean, D.D.4    Budde, M.D.5    Frank, J.A.6
  • 29
    • 84922051656 scopus 로고    scopus 로고
    • Macrophage activation and its role in repair and pathology after spinal cord injury
    • Gensel, J.C. and Zhang, B. (2015). Macrophage activation and its role in repair and pathology after spinal cord injury. Brain Res. 1619, 1-11
    • (2015) Brain Res. , vol.1619 , pp. 1-11
    • Gensel, J.C.1    Zhang, B.2
  • 31
    • 84864210630 scopus 로고    scopus 로고
    • Temporal changes in cell marker expression and cellular infiltration in a controlled cortical impact model in adult male C57BL/6 mice
    • Jin, X., Ishii, H., Bai, Z., Itokazu, T., and Yamashita, T. (2012). Temporal changes in cell marker expression and cellular infiltration in a controlled cortical impact model in adult male C57BL/6 mice. PLoS One 7, e41892.
    • (2012) PLoS One , vol.7 , pp. e41892
    • Jin, X.1    Ishii, H.2    Bai, Z.3    Itokazu, T.4    Yamashita, T.5
  • 33
    • 84929513192 scopus 로고    scopus 로고
    • Interacting chemokine signals regulate dendritic cells in acute brain injury
    • Israelsson, C., Kylberg, A., Bengtsson, H., Hillered, L., Ebendal, T. (2014). Interacting chemokine signals regulate dendritic cells in acute brain injury. PLoS One 9, e104754.
    • (2014) PLoS One , vol.9 , pp. e104754
    • Israelsson, C.1    Kylberg, A.2    Bengtsson, H.3    Hillered, L.4    Ebendal, T.5
  • 34
    • 84920996965 scopus 로고    scopus 로고
    • CCR2 Antagonism alters brain macrophage polarization and ameliorates cognitive dysfunction induced by traumatic brain injury
    • Morganti, J.M., Jopson, T.D., Liu, S., Riparip, L.K., Guandique, C.K., Gupta, N., Ferguson, A.R., and Rosi, S. (2015). CCR2 Antagonism alters brain macrophage polarization and ameliorates cognitive dysfunction induced by traumatic brain injury. J. Neurosci. 35, 748-760.
    • (2015) J. Neurosci. , vol.35 , pp. 748-760
    • Morganti, J.M.1    Jopson, T.D.2    Liu, S.3    Riparip, L.K.4    Guandique, C.K.5    Gupta, N.6    Ferguson, A.R.7    Rosi, S.8
  • 35
    • 77957028140 scopus 로고    scopus 로고
    • Microglial activation and chronic neurodegeneration
    • Lull, M.E. and Block, M.L. (2010). Microglial activation and chronic neurodegeneration. Neurotherapeutics 7, 354-365.
    • (2010) Neurotherapeutics , vol.7 , pp. 354-365
    • Lull, M.E.1    Block, M.L.2
  • 36
    • 0346463000 scopus 로고    scopus 로고
    • NADPH oxidase mediates lipopolysaccharideinduced neurotoxicity and proinflammatory gene expression in activated microglia
    • Qin, L., Liu, Y., Wang, T., Wei, S.J., Block, M.L., Wilson, B., Liu, B., and Hong, J.S. (2004). NADPH oxidase mediates lipopolysaccharideinduced neurotoxicity and proinflammatory gene expression in activated microglia. J. Biol. Chem. 279, 1415-1421.
    • (2004) J. Biol. Chem. , vol.279 , pp. 1415-1421
    • Qin, L.1    Liu, Y.2    Wang, T.3    Wei, S.J.4    Block, M.L.5    Wilson, B.6    Liu, B.7    Hong, J.S.8
  • 37
    • 27344458546 scopus 로고    scopus 로고
    • Activation of microglial NADPH oxidase is synergistic with glial iNOS expression in inducing neuronal death: A dual-key mechanism of inflammatory neurodegeneration
    • Mander, P. and Brown, G.C. (2005). Activation of microglial NADPH oxidase is synergistic with glial iNOS expression in inducing neuronal death: a dual-key mechanism of inflammatory neurodegeneration. J. Neuroinflammation 2, 20.
    • (2005) J. Neuroinflammation , vol.2 , pp. 20
    • Mander, P.1    Brown, G.C.2
  • 38
    • 3442888512 scopus 로고    scopus 로고
    • Redox regulation of glial inflammatory response to lipopolysaccharide and interferongamma
    • Pawate, S., Shen, Q., Fan, F., and Bhat, N.R. (2004). Redox regulation of glial inflammatory response to lipopolysaccharide and interferongamma. J. Neurosci. Res. 77, 540-551.
    • (2004) J. Neurosci. Res. , vol.77 , pp. 540-551
    • Pawate, S.1    Shen, Q.2    Fan, F.3    Bhat, N.R.4
  • 39
    • 79954628624 scopus 로고    scopus 로고
    • NADPH oxidase is involved in post-ischemic brain inflammation
    • Chen, H., Kim, G.S., Okami, N., Narasimhan, P., and Chan, P.H. (2011). NADPH oxidase is involved in post-ischemic brain inflammation. Neurobiol. Dis. 42, 341-348.
    • (2011) Neurobiol. Dis. , vol.42 , pp. 341-348
    • Chen, H.1    Kim, G.S.2    Okami, N.3    Narasimhan, P.4    Chan, P.H.5
  • 40
    • 67649852282 scopus 로고    scopus 로고
    • Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion
    • Chen, H., Song, Y.S., and Chan, P.H. (2009). Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion. J. Cereb. Blood Flow Metab. 29, 1262-1272.
    • (2009) J. Cereb. Blood Flow Metab. , vol.29 , pp. 1262-1272
    • Chen, H.1    Song, Y.S.2    Chan, P.H.3
  • 41
    • 84857393097 scopus 로고    scopus 로고
    • Delayed mGluR5 activation limits neuroinflammation and neurodegeneration after traumatic brain injury
    • Byrnes, K.R., Loane, D.J., Stoica, B.A., Zhang, J., and Faden, A.I. (2012). Delayed mGluR5 activation limits neuroinflammation and neurodegeneration after traumatic brain injury. J. Neuroinflammation 9, 43.
    • (2012) J. Neuroinflammation , vol.9 , pp. 43
    • Byrnes, K.R.1    Loane, D.J.2    Stoica, B.A.3    Zhang, J.4    Faden, A.I.5
  • 42
    • 84859224136 scopus 로고    scopus 로고
    • Critical role of NADPH oxidase in neuronal oxidative damage and microglia activation following traumatic brain injury
    • Zhang, Q.G., Laird, M.D., Han, D., Nguyen, K., Scott, E., Dong, Y., Dhandapani, K.M., and Brann, D.W. (2012). Critical role of NADPH oxidase in neuronal oxidative damage and microglia activation following traumatic brain injury. PLoS One 7, e34504.
    • (2012) PLoS One , vol.7 , pp. e34504
    • Zhang, Q.G.1    Laird, M.D.2    Han, D.3    Nguyen, K.4    Scott, E.5    Dong, Y.6    Dhandapani, K.M.7    Brann, D.W.8
  • 43
    • 84867096605 scopus 로고    scopus 로고
    • Prevention of traumatic brain injury-induced neuronal death by inhibition of NADPH oxidase activation
    • Choi, B.Y., Jang, B.G., Kim, J.H., Lee, B.E., Sohn, M., Song, H.K., and Suh, S.W. (2012). Prevention of traumatic brain injury-induced neuronal death by inhibition of NADPH oxidase activation. Brain Res. 1481, 49-58.
    • (2012) Brain Res. , vol.1481 , pp. 49-58
    • Choi, B.Y.1    Jang, B.G.2    Kim, J.H.3    Lee, B.E.4    Sohn, M.5    Song, H.K.6    Suh, S.W.7
  • 45
    • 84874724195 scopus 로고    scopus 로고
    • Activation of mGluR5 and inhibition of NADPH oxidase improves functional recovery after traumatic brain injury
    • Loane, D.J., Stoica, B.A., Byrnes, K.R., Jeong, W., and Faden, A.I. (2013). Activation of mGluR5 and inhibition of NADPH oxidase improves functional recovery after traumatic brain injury. J. Neurotrauma 30, 403-412.
    • (2013) J. Neurotrauma , vol.30 , pp. 403-412
    • Loane, D.J.1    Stoica, B.A.2    Byrnes, K.R.3    Jeong, W.4    Faden, A.I.5
  • 46
    • 84863845583 scopus 로고    scopus 로고
    • Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS
    • Liao, B., Zhao, W., Beers, D.R., Henkel, J.S., and Appel, S.H. (2012). Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS. Exp. Neurol. 237, 147-152.
    • (2012) Exp. Neurol. , vol.237 , pp. 147-152
    • Liao, B.1    Zhao, W.2    Beers, D.R.3    Henkel, J.S.4    Appel, S.H.5
  • 47
    • 84155164228 scopus 로고    scopus 로고
    • Inhibition of NADPH oxidase promotes alternative and antiinflammatory microglial activation during neuroinflammation
    • Choi, S.H., Aid, S., Kim, H.W., Jackson, S.H., and Bosetti, F. (2012). Inhibition of NADPH oxidase promotes alternative and antiinflammatory microglial activation during neuroinflammation. J. Neurochem. 120, 292-301.
    • (2012) J. Neurochem. , vol.120 , pp. 292-301
    • Choi, S.H.1    Aid, S.2    Kim, H.W.3    Jackson, S.H.4    Bosetti, F.5
  • 48
    • 79959379095 scopus 로고    scopus 로고
    • Repertoire of microglial and macrophage responses after spinal cord injury
    • David, S. and Kroner, A. (2011). Repertoire of microglial and macrophage responses after spinal cord injury. Nat. Rev. 12, 388-399.
    • (2011) Nat. Rev. , vol.12 , pp. 388-399
    • David, S.1    Kroner, A.2
  • 49
    • 84908028367 scopus 로고    scopus 로고
    • TNF and increased intracellular iron alter macrophage polarization to a detrimental M1 phenotype in the injured spinal cord
    • Kroner, A., Greenhalgh, A.D., Zarruk, J.G., Passos Dos Santos, R., Gaestel, M., and David, S. (2014). TNF and increased intracellular iron alter macrophage polarization to a detrimental M1 phenotype in the injured spinal cord. Neuron 83, 1098-1116.
    • (2014) Neuron , vol.83 , pp. 1098-1116
    • Kroner, A.1    Greenhalgh, A.D.2    Zarruk, J.G.3    Passos Dos Santos, R.4    Gaestel, M.5    David, S.6
  • 52
    • 84903160194 scopus 로고    scopus 로고
    • IL-4 signaling drives a unique arginase+/IL-1beta+ microglia phenotype and recruits macrophages to the inflammatory CNS: Consequences of age-related deficits in IL-4Ralpha after traumatic spinal cord injury
    • Fenn, A.M., Hall, J.C., Gensel, J.C., Popovich, P.G., and Godbout, J.P. (2014). IL-4 signaling drives a unique arginase+/IL-1beta+ microglia phenotype and recruits macrophages to the inflammatory CNS: consequences of age-related deficits in IL-4Ralpha after traumatic spinal cord injury. J. Neurosci. 34, 8904-8917.
    • (2014) J. Neurosci. , vol.34 , pp. 8904-8917
    • Fenn, A.M.1    Hall, J.C.2    Gensel, J.C.3    Popovich, P.G.4    Godbout, J.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.