Biological implications of somatic DDX41 p.R525H mutation in acute myeloid leukemia

Experimental Hematology

Volumn 44, Issue 8, 2016, Pages 745-754.e4

  Kadono, Moe ^a   Kanai, Akinori ^a   Nagamachi, Akiko ^a   Shinriki, Satoru ^b,c   Kawata, Jin ^c   Iwato, Koji ^d   Kyo, Taiichi ^d   Oshima, Kumi ^a   Yokoyama, Akihiko ^e   Kawamura, Takeshi ^f   Nagase, Reina ^g   Inoue, Daichi ^g   Kitamura, Toshio ^g   Inaba, Toshiya ^a   Ichinohe, Tatsuo ^a   Matsui, Hirotaka ^a,b,c  

^a HIROSHIMA UNIVERSITY   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

^c KUMAMOTO UNIVERSITY HOSPITAL   (Japan)

^d ATOMIC BOMB SURVIVORS HOSPITAL   (Japan)

^e KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^f UNIVERSITY OF TOKYO   (Japan)

^g UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CD34 ANTIGEN; DDX41 PROTEIN; HISTIDINE; MESSENGER RNA; MUTANT PROTEIN; PROTEIN MDM2; RETINOBLASTOMA PROTEIN; RIBOSOME RNA; RNA HELICASE; TRANSCRIPTION FACTOR E2F; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; CODON; DDX41 PROTEIN, HUMAN; DEAD BOX PROTEIN; PROTEIN BINDING;

ACUTE MYELOBLASTIC LEUKEMIA; ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD CELL; CANCER PATIENT; CELL COUNT; CELL DAMAGE; CELL DIFFERENTIATION; CELL GROWTH; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOPENIA; DDX41 GENE; EPIGENETICS; GROWTH RATE; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; LEUKEMIA CELL; LEUKEMIA CELL LINE; LEUKEMOGENESIS; MALE; MIDDLE AGED; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA PROCESSING; RNA SEQUENCE; SOMATIC MUTATION; TRANSCRIPTION REGULATION; UMBILICAL CORD BLOOD; AMINO ACID SUBSTITUTION; ANIMAL; BONE MARROW TRANSPLANTATION; CHROMOSOME ABERRATION; CODON; DISEASE MODEL; DNA MUTATIONAL ANALYSIS; FEMALE; GENE EXPRESSION; GENETIC PREDISPOSITION; GENETICS; HEMATOPOIETIC STEM CELL; LEUKEMIA, MYELOID, ACUTE; METABOLISM; MUTATION; PROTEIN TRANSPORT; VERY ELDERLY;

AGED; AGED, 80 AND OVER; AMINO ACID SUBSTITUTION; ANIMALS; BIOMARKERS; BONE MARROW TRANSPLANTATION; CHROMOSOME ABERRATIONS; CODON; DEAD-BOX RNA HELICASES; DISEASE MODELS, ANIMAL; DNA MUTATIONAL ANALYSIS; FEMALE; GENE EXPRESSION; GENETIC PREDISPOSITION TO DISEASE; HEMATOPOIETIC STEM CELLS; HUMANS; LEUKEMIA, MYELOID, ACUTE; MALE; MICE; MIDDLE AGED; MUTATION; PROTEIN BINDING; PROTEIN TRANSPORT;

EID: 84989917663     PISSN: 0301472X     EISSN: 18732399     Source Type: Journal    
DOI: 10.1016/j.exphem.2016.04.017     Document Type: Article

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