Lack of p53 expression in human myeloid leukemias is not due to mutations in transcriptional regulatory regions of the gene [5]

Leukemia

Volumn 16, Issue 10, 2002, Pages 2165-2167

  Durland Busbie, S ^a   Reisman, D ^a  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; MESSENGER RNA; PROTEIN P53;

BASE PAIRING; CONTROLLED STUDY; FIBROBLAST; GENE CONTROL; GENE DELETION; GENE EXPRESSION; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LETTER; MYELOID LEUKEMIA; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; SEQUENCE ANALYSIS; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE; WILD TYPE;

EID: 0036798565     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2402647     Document Type: Letter

References (6)

1. Vousden KH. p53: death star. Cell 2000; 103:691-694.
2. Stuart ET, Haffner R, Oren M, Gruss P. Loss of p53 function through PAX-mediated transcriptional repression. EMBO J 1995; 22: 5638-5645.
3. Raman V, Martensen SA, Reisman D, Evron E, Odenwald WF, Jaffee E, Marks J, Sukumar S. Control of p53 trancription by HOXA5 may play a role in breast cancer. Nature 2000; 405: 974-978.
4. Prokocimer M, Harris N, Brill E, Rotter V. Expression of p53 in human leukemia and lymphoma. Rec Adv Leuk Lymp 1987; 61: 243-264.
5. Sakai T, Ohtani N, McGee TL, Robbins PD, Dryja T. Oncogenic germ-line mutations in Sp1 and ATF sites in the human retinoblastoma gene. Nature 1991; 353:83-86.
6. Reisman D, Greenberg M, Rotter V. Human p53 oncogene contains one promoter upstream of exon 1 and a second stronger promoter within intron 1. Proc Natl Acad Sci USA 1988; 85: 5146-5150.