Suprainduction of p53 by disruption of 40S and 60S ribosome biogenesis leads to the activation of a novel G2/M checkpoint

Genes and Development

Volumn 26, Issue 10, 2012, Pages 1028-1040

  Fumagalli, Stefano ^a,b   Ivanenkov, Vasily V ^a   Teng, Teng ^a,c   Thomas, George ^a,d  

^a Metabolic Disease Institute   (United States)

^b INSERM   (France)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^d BELLVITGE BIOMEDICAL RESEARCH INSTITUTE IDIBELL   (Spain)

Author keywords

5'TOP translation; G2 M checkpoint; P53; RPL11

Indexed keywords

DACTINOMYCIN; PROTEIN MDM2; PROTEIN P53; RIBOSOME PROTEIN; RIBOSOME PROTEIN L11; RIBOSOME PROTEIN L23; RIBOSOME PROTEIN L5; RIBOSOME PROTEIN S7; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; BIOGENESIS; CELL DISRUPTION; CONFOCAL MICROSCOPY; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINT; M PHASE CELL CYCLE CHECKPOINT; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RIBOSOME; TRANSLATION INITIATION; UPREGULATION; WESTERN BLOTTING;

CELL LINE, TUMOR; G2 PHASE CELL CYCLE CHECKPOINTS; HUMANS; PROTEIN BIOSYNTHESIS; RIBOSOMAL PROTEINS; RIBOSOME SUBUNITS, LARGE, EUKARYOTIC; RIBOSOME SUBUNITS, SMALL, EUKARYOTIC; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84861170072     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.189951.112     Document Type: Article

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