Bcl11a Deficiency Leads to Hematopoietic Stem Cell Defects with an Aging-like Phenotype

Cell Reports

Volumn 16, Issue 12, 2016, Pages 3181-3194

  Luc, Sidinh ^a,b,c   Huang, Jialiang ^a,b,c,d   McEldoon, Jennifer L ^a,b,c   Somuncular, Ece ^a,b,c   Li, Dan ^a,b,c   Rhodes, Claire ^a,b,c   Mamoor, Shahan ^a,b,c   Hou, Serena ^a,b,c   Xu, Jian ^e,f   Orkin, Stuart H ^a,b,c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^f UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 6; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR BCL11A; UNCLASSIFIED DRUG; BCL11A PROTEIN, MOUSE; CARRIER PROTEIN; CDK6 PROTEIN, MOUSE; NUCLEAR PROTEIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL AGING; CELL CYCLE REGULATION; CELL DIFFERENTIATION; CELL DISRUPTION; CELL FUNCTION; DOWN REGULATION; EMBRYO DEVELOPMENT; GENE EXPRESSION PROFILING; HEMATOPOIETIC STEM CELL; KNOCKOUT MOUSE; LYMPHOPOIESIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; STEM CELL SELF-RENEWAL; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; GENETICS; HEMATOPOIESIS; PATHOLOGY;

ANIMALS; CARRIER PROTEINS; CELLULAR SENESCENCE; CYCLIN-DEPENDENT KINASE 6; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NUCLEAR PROTEINS; PHENOTYPE;

EID: 84989884580     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.08.064     Document Type: Article

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