Protective effect of autophagy on human retinal pigment epithelial cells against lipofuscin fluorophore A2E: Implications for age-related macular degeneration

Cell Death and Disease

Volumn 6, Issue 11, 2015, Pages

  Zhang, J ^a,b,c   Bai, Y ^a,b,c   Huang, L ^a,b,c   Qi, Y ^a,b,c   Zhang, Q ^a,b,c   Li, S ^a,b,c   Wu, Y ^d   Li, X ^a,b,c  

^a PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^c Beijing Key Laboratory for Diagnosis and Treatment of Retinal and Choroid Diseases   (China)

^d XIAMEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLADENINE; ANGIOGENIC FACTOR; BECLIN 1; BIS RETINOID N RETINYL N RETINYLIDENE ETHANOLAMINE; FLUOROPHORE A2E; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 22; INTERLEUKIN 6; INTERLEUKIN 8; INTRACELLULAR ADHESION MOLECULE; LIPOFUSCIN; MAMMALIAN TARGET OF RAPAMYCIN; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN; PROTEIN KINASE B; PROTEIN LC3; PROTEIN LC3 II; RAPAMYCIN; STROMAL CELL DERIVED FACTOR 1; UNCLASSIFIED DRUG; VASCULOTROPIN A; A2-E (N-RETINYLIDENE-N-RETINYLETHANOLAMINE); RETINOID; VISUAL PIGMENT;

AGE RELATED MACULAR DEGENERATION; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL PROLIFERATION; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RELEASE; EPITHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; INFLAMMATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINAL PIGMENT EPITHELIUM; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING; MACULAR DEGENERATION; METABOLISM; PATHOLOGY; PHYSIOLOGY;

AUTOPHAGY; CELL PROLIFERATION; HUMANS; MACULAR DEGENERATION; RETINAL PIGMENT EPITHELIUM; RETINAL PIGMENTS; RETINOIDS;

EID: 84989870709     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2015.330     Document Type: Article

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