-
1
-
-
30344434647
-
Evolutionary causes and consequences of immunopathology
-
Graham, A. L., Allen, J. E., Read, A. F. Evolutionary causes and consequences of immunopathology. Annu Rev Ecol Evol S 36, 373-397 (2005).
-
(2005)
Annu Rev Ecol Evol S
, vol.36
, pp. 373-397
-
-
Graham, A.L.1
Allen, J.E.2
Read, A.F.3
-
2
-
-
33748978015
-
Self-harm caused by an insect's innate immunity
-
Sadd, B. M., Siva-Jothy, M. T. Self-harm caused by an insect's innate immunity. Proc Biol Sci 273, 2571-2574 (2006).
-
(2006)
Proc Biol Sci
, vol.273
, pp. 2571-2574
-
-
Sadd, B.M.1
Siva-Jothy, M.T.2
-
3
-
-
77954069495
-
Mechanisms of immune-mediated liver injury
-
Adams, D. H., Ju, C., Ramaiah, S. K., Uetrecht, J., Jaeschke, H. Mechanisms of immune-mediated liver injury. Toxicol Sci 115, 307-321 (2010).
-
(2010)
Toxicol Sci
, vol.115
, pp. 307-321
-
-
Adams, D.H.1
Ju, C.2
Ramaiah, S.K.3
Uetrecht, J.4
Jaeschke, H.5
-
4
-
-
84859404292
-
Lung dendritic cells in respiratory viral infection and asthma: From protection to immunopathology
-
Lambrecht, B. N., Hammad, H. Lung dendritic cells in respiratory viral infection and asthma: from protection to immunopathology. Annu Rev Immunol 30, 243-270 (2012).
-
(2012)
Annu Rev Immunol
, vol.30
, pp. 243-270
-
-
Lambrecht, B.N.1
Hammad, H.2
-
5
-
-
80052202803
-
Contribution of cytokines to pathology and protection in virus infection
-
Wack, A., Openshaw, P., O'Garra, A. Contribution of cytokines to pathology and protection in virus infection. Curr Opin Virol 1, 184-195 (2011).
-
(2011)
Curr Opin Virol
, vol.1
, pp. 184-195
-
-
Wack, A.1
Openshaw, P.2
O'Garra, A.3
-
6
-
-
84872027397
-
Clearing the dead: Apoptotic cell sensing, recognition, engulfment, and digestion
-
Hochreiter-Hufford, A., Ravichandran, K. S. Clearing the dead: apoptotic cell sensing, recognition, engulfment, and digestion. Cold Spring Harb Perspect Biol 5, a008748 (2013).
-
(2013)
Cold Spring Harb Perspect Biol
, vol.5
, pp. a008748
-
-
Hochreiter-Hufford, A.1
Ravichandran, K.S.2
-
7
-
-
84951317601
-
Type i interferon restricts type 2 immunopathology through the regulation of group 2 innate lymphoid cells
-
Duerr, C. U. et al. Type I interferon restricts type 2 immunopathology through the regulation of group 2 innate lymphoid cells. Nat Immunol 17, 65-75 (2016).
-
(2016)
Nat Immunol
, vol.17
, pp. 65-75
-
-
Duerr, C.U.1
-
8
-
-
84922482118
-
Vaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infection
-
Penaloza-MacMaster, P. et al. Vaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infection. Science 347, 278-282 (2015).
-
(2015)
Science
, vol.347
, pp. 278-282
-
-
Penaloza-MacMaster, P.1
-
9
-
-
77950365906
-
Nonresolving inflammation
-
Nathan, C., Ding, A. Nonresolving inflammation. Cell 140, 871-882 (2010).
-
(2010)
Cell
, vol.140
, pp. 871-882
-
-
Nathan, C.1
Ding, A.2
-
10
-
-
84860250554
-
Infection regulates pro-resolving mediators that lower antibiotic requirements
-
Chiang, N. et al. Infection regulates pro-resolving mediators that lower antibiotic requirements. Nature 484, 524-528 (2012).
-
(2012)
Nature
, vol.484
, pp. 524-528
-
-
Chiang, N.1
-
11
-
-
84901921079
-
Pro-resolving lipid mediators are leads for resolution physiology
-
Serhan, C. N. Pro-resolving lipid mediators are leads for resolution physiology. Nature 510, 92-101 (2014).
-
(2014)
Nature
, vol.510
, pp. 92-101
-
-
Serhan, C.N.1
-
12
-
-
0030046797
-
Identification of scavenger receptor SR-BI as a high density lipoprotein receptor
-
Acton, S. et al. Identification of scavenger receptor SR-BI as a high density lipoprotein receptor. Science 271, 518-520 (1996).
-
(1996)
Science
, vol.271
, pp. 518-520
-
-
Acton, S.1
-
13
-
-
0034721864
-
Scavenger receptor BI transfers major lipoprotein-associated phospholipids into the cells
-
Urban, S. et al. Scavenger receptor BI transfers major lipoprotein-associated phospholipids into the cells. J Biol Chem 275, 33409-33415 (2000).
-
(2000)
J Biol Chem
, vol.275
, pp. 33409-33415
-
-
Urban, S.1
-
14
-
-
18644378971
-
The human scavenger receptor class B type i is a novel candidate receptor for the hepatitis C virus
-
Scarselli, E. et al. The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus. Embo Journal 21, 5017-5025 (2002).
-
(2002)
Embo Journal
, vol.21
, pp. 5017-5025
-
-
Scarselli, E.1
-
15
-
-
33750943039
-
CLA-1 and its splicing variant CLA-2 mediate bacterial adhesion and cytosolic bacterial invasion in mammalian cells
-
Vishnyakova, T. G. et al. CLA-1 and its splicing variant CLA-2 mediate bacterial adhesion and cytosolic bacterial invasion in mammalian cells. Proc Natl Acad Sci USA 103, 16888-16893 (2006).
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 16888-16893
-
-
Vishnyakova, T.G.1
-
16
-
-
84886646838
-
Immune surveillance by the liver
-
Jenne, C. N., Kubes, P. Immune surveillance by the liver. Nat Immunol 14, 996-1006 (2013).
-
(2013)
Nat Immunol
, vol.14
, pp. 996-1006
-
-
Jenne, C.N.1
Kubes, P.2
-
17
-
-
84883181808
-
Sterols and oxysterols in immune cell function
-
Spann, N. J., Glass, C. K. Sterols and oxysterols in immune cell function. Nat Immunol 14, 893-900 (2013).
-
(2013)
Nat Immunol
, vol.14
, pp. 893-900
-
-
Spann, N.J.1
Glass, C.K.2
-
18
-
-
33646175602
-
Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice
-
Saleh, M. et al. Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice. Nature 440, 1064-1068 (2006).
-
(2006)
Nature
, vol.440
, pp. 1064-1068
-
-
Saleh, M.1
-
19
-
-
78650605318
-
Biliary cholesterol secretion: More than a simple ABC
-
Dikkers, A., Tietge, U. J. Biliary cholesterol secretion: more than a simple ABC. World J Gastroenterol 16, 5936-5945 (2010).
-
(2010)
World J Gastroenterol
, vol.16
, pp. 5936-5945
-
-
Dikkers, A.1
Tietge, U.J.2
-
20
-
-
79959242498
-
Detection of prokaryotic mRNA signifies microbial viability and promotes immunity
-
Sander, L. E. et al. Detection of prokaryotic mRNA signifies microbial viability and promotes immunity. Nature 474, 385-389 (2011).
-
(2011)
Nature
, vol.474
, pp. 385-389
-
-
Sander, L.E.1
-
21
-
-
78649594684
-
Bacteria-induced phagocyte secondary necrosis as a pathogenicity mechanism
-
Silva, M. T. Bacteria-induced phagocyte secondary necrosis as a pathogenicity mechanism. J Leukoc Biol 88, 885-896 (2010).
-
(2010)
J Leukoc Biol
, vol.88
, pp. 885-896
-
-
Silva, M.T.1
-
22
-
-
84901358607
-
Monocytes and macrophages: Developmental pathways and tissue homeostasis
-
Ginhoux, F., Jung, S. Monocytes and macrophages: developmental pathways and tissue homeostasis. Nat Rev Immunol 14, 392-404 (2014).
-
(2014)
Nat Rev Immunol
, vol.14
, pp. 392-404
-
-
Ginhoux, F.1
Jung, S.2
-
23
-
-
80052845560
-
Caspase-8 regulates TNF-alpha-induced epithelial necroptosis and terminal ileitis
-
Gunther, C. et al. Caspase-8 regulates TNF-alpha-induced epithelial necroptosis and terminal ileitis. Nature 477, 335-339 (2011).
-
(2011)
Nature
, vol.477
, pp. 335-339
-
-
Gunther, C.1
-
24
-
-
0035942169
-
Selective binding of perfringolysin O derivative to cholesterol-rich membrane microdomains (rafts)
-
Waheed, A. A. et al. Selective binding of perfringolysin O derivative to cholesterol-rich membrane microdomains (rafts). Proc Natl Acad Sci USA 98, 4926-4931 (2001).
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 4926-4931
-
-
Waheed, A.A.1
-
25
-
-
84904647870
-
Cytosolic lipid droplets: From mechanisms of fat storage to disease
-
Gross, D. A., Silver, D. L. Cytosolic lipid droplets: from mechanisms of fat storage to disease. Crit Rev Biochem Mol Biol 49, 304-326 (2014).
-
(2014)
Crit Rev Biochem Mol Biol
, vol.49
, pp. 304-326
-
-
Gross, D.A.1
Silver, D.L.2
-
26
-
-
77049128273
-
Actin dynamics drive membrane reorganization and scission in clathrin-independent endocytosis
-
Romer, W. et al. Actin dynamics drive membrane reorganization and scission in clathrin-independent endocytosis. Cell 140, 540-553 (2010).
-
(2010)
Cell
, vol.140
, pp. 540-553
-
-
Romer, W.1
-
27
-
-
0032898743
-
Comparison of class B scavenger receptors, CD36 and scavenger receptor BI (SR-BI), shows that both receptors mediate high density lipoprotein-cholesteryl ester selective uptake but SR-BI exhibits a unique enhancement of cholesteryl ester uptake
-
Connelly, M. A., Klein, S. M., Azhar, S., Abumrad, N. A., Williams, D. L. Comparison of class B scavenger receptors, CD36 and scavenger receptor BI (SR-BI), shows that both receptors mediate high density lipoprotein-cholesteryl ester selective uptake but SR-BI exhibits a unique enhancement of cholesteryl ester uptake. J Biol Chem 274, 41-47 (1999).
-
(1999)
J Biol Chem
, vol.274
, pp. 41-47
-
-
Connelly, M.A.1
Klein, S.M.2
Azhar, S.3
Abumrad, N.A.4
Williams, D.L.5
-
28
-
-
65449120034
-
Virus entry by macropinocytosis
-
Mercer, J., Helenius, A. Virus entry by macropinocytosis. Nat Cell Biol 11, 510-520 (2009).
-
(2009)
Nat Cell Biol
, vol.11
, pp. 510-520
-
-
Mercer, J.1
Helenius, A.2
-
29
-
-
84878396462
-
Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
-
Commisso, C. et al. Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells. Nature 497, 633-637 (2013).
-
(2013)
Nature
, vol.497
, pp. 633-637
-
-
Commisso, C.1
-
30
-
-
0033605386
-
Role of class B scavenger receptor type i in phagocytosis of apoptotic rat spermatogenic cells by Sertoli cells
-
Shiratsuchi, A., Kawasaki, Y., Ikemoto, M., Arai, H., Nakanishi, Y. Role of class B scavenger receptor type I in phagocytosis of apoptotic rat spermatogenic cells by Sertoli cells. J Biol Chem 274, 5901-5908 (1999).
-
(1999)
J Biol Chem
, vol.274
, pp. 5901-5908
-
-
Shiratsuchi, A.1
Kawasaki, Y.2
Ikemoto, M.3
Arai, H.4
Nakanishi, Y.5
-
31
-
-
4444329588
-
Role of lipid rafts in E-cadherin-and HGF-R/Met-mediated entry of Listeria monocytogenes into host cells
-
Seveau, S., Bierne, H., Giroux, S., Prevost, M. C., Cossart, P. Role of lipid rafts in E-cadherin-and HGF-R/Met-mediated entry of Listeria monocytogenes into host cells. J Cell Biol 166, 743-753 (2004).
-
(2004)
J Cell Biol
, vol.166
, pp. 743-753
-
-
Seveau, S.1
Bierne, H.2
Giroux, S.3
Prevost, M.C.4
Cossart, P.5
-
32
-
-
84872959202
-
Caveolae as plasma membrane sensors, protectors and organizers
-
Parton, R. G., del Pozo, M. A. Caveolae as plasma membrane sensors, protectors and organizers. Nat Rev Mol Cell Biol 14, 98-112 (2013).
-
(2013)
Nat Rev Mol Cell Biol
, vol.14
, pp. 98-112
-
-
Parton, R.G.1
Del Pozo, M.A.2
-
33
-
-
84861079602
-
Lipid bodies: Inflammatory organelles implicated in host-Trypanosoma cruzi interplay during innate immune responses
-
D'Avila, H., Toledo, D. A., Melo, R. C. Lipid bodies: inflammatory organelles implicated in host-Trypanosoma cruzi interplay during innate immune responses. Mediators Inflamm 2012, 478601 (2012).
-
(2012)
Mediators Inflamm
, vol.2012
, pp. 478601
-
-
D'Avila, H.1
Toledo, D.A.2
Melo, R.C.3
-
34
-
-
78751672975
-
Autophagy in immunity and inflammation
-
Levine, B., Mizushima, N., Virgin, H. W. Autophagy in immunity and inflammation. Nature 469, 323-335 (2011).
-
(2011)
Nature
, vol.469
, pp. 323-335
-
-
Levine, B.1
Mizushima, N.2
Virgin, H.W.3
-
35
-
-
0034329418
-
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
-
Kabeya, Y. et al. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing. EMBO J 19, 5720-5728 (2000).
-
(2000)
EMBO J
, vol.19
, pp. 5720-5728
-
-
Kabeya, Y.1
-
36
-
-
81055144784
-
Autophagy: Renovation of cells and tissues
-
Mizushima, N., Komatsu, M. Autophagy: renovation of cells and tissues. Cell 147, 728-741 (2011).
-
(2011)
Cell
, vol.147
, pp. 728-741
-
-
Mizushima, N.1
Komatsu, M.2
-
37
-
-
0037711625
-
Cytoplasmic bacteria can be targets for autophagy
-
Rich, K. A., Burkett, C., Webster, P. Cytoplasmic bacteria can be targets for autophagy. Cell Microbiol 5, 455-468 (2003).
-
(2003)
Cell Microbiol
, vol.5
, pp. 455-468
-
-
Rich, K.A.1
Burkett, C.2
Webster, P.3
-
38
-
-
84864991509
-
Atg9 vesicles are an important membrane source during early steps of autophagosome formation
-
Yamamoto, H. et al. Atg9 vesicles are an important membrane source during early steps of autophagosome formation. J Cell Biol 198, 219-233 (2012).
-
(2012)
J Cell Biol
, vol.198
, pp. 219-233
-
-
Yamamoto, H.1
-
39
-
-
12744273521
-
Golgi vesiculation induced by cholesterol occurs by a dynamin-and cPLA2-dependent mechanism
-
Grimmer, S., Ying, M., Walchli, S., van Deurs, B., Sandvig, K. Golgi vesiculation induced by cholesterol occurs by a dynamin-and cPLA2-dependent mechanism. Traffic 6, 144-156 (2005).
-
(2005)
Traffic
, vol.6
, pp. 144-156
-
-
Grimmer, S.1
Ying, M.2
Walchli, S.3
Van Deurs, B.4
Sandvig, K.5
-
40
-
-
84866431810
-
Shigella effector IpaB-induced cholesterol relocation disrupts the Golgi complex and recycling network to inhibit host cell secretion
-
Mounier, J. et al. Shigella effector IpaB-induced cholesterol relocation disrupts the Golgi complex and recycling network to inhibit host cell secretion. Cell Host Microbe 12, 381-389 (2012).
-
(2012)
Cell Host Microbe
, vol.12
, pp. 381-389
-
-
Mounier, J.1
-
41
-
-
84857195479
-
Activation of autophagy by inflammatory signals limits IL-1beta production by targeting ubiquitinated inflammasomes for destruction
-
Shi, C. S. et al. Activation of autophagy by inflammatory signals limits IL-1beta production by targeting ubiquitinated inflammasomes for destruction. Nat Immunol 13, 255-263 (2012).
-
(2012)
Nat Immunol
, vol.13
, pp. 255-263
-
-
Shi, C.S.1
-
42
-
-
77955501642
-
Cutting edge: Cytosolic bacterial DNA activates the inflammasome via Aim2
-
Warren, S. E. et al. Cutting edge: Cytosolic bacterial DNA activates the inflammasome via Aim2. J Immunol 185, 818-821 (2010).
-
(2010)
J Immunol
, vol.185
, pp. 818-821
-
-
Warren, S.E.1
-
43
-
-
84863393597
-
Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis
-
He, C. et al. Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis. Nature 481, 511-515 (2012).
-
(2012)
Nature
, vol.481
, pp. 511-515
-
-
He, C.1
-
44
-
-
84920072385
-
Antimicrobial inflammasomes: Unified signalling against diverse bacterial pathogens
-
Eldridge, M. J., Shenoy, A. R. Antimicrobial inflammasomes: unified signalling against diverse bacterial pathogens. Curr Opin Microbiol 23, 32-41 (2015).
-
(2015)
Curr Opin Microbiol
, vol.23
, pp. 32-41
-
-
Eldridge, M.J.1
Shenoy, A.R.2
-
45
-
-
0033557291
-
Macrophage microbicidal mechanisms in vivo: Reactive nitrogen versus oxygen intermediates in the killing of intracellular visceral Leishmania donovani
-
Murray, H. W., Nathan, C. F. Macrophage microbicidal mechanisms in vivo: reactive nitrogen versus oxygen intermediates in the killing of intracellular visceral Leishmania donovani. J Exp Med 189, 741-746 (1999).
-
(1999)
J Exp Med
, vol.189
, pp. 741-746
-
-
Murray, H.W.1
Nathan, C.F.2
-
46
-
-
38049123476
-
Clearance of apoptotic cells by phagocytes
-
Erwig, L. P., Henson, P. M. Clearance of apoptotic cells by phagocytes. Cell Death Differ 15, 243-250 (2008).
-
(2008)
Cell Death Differ
, vol.15
, pp. 243-250
-
-
Erwig, L.P.1
Henson, P.M.2
-
47
-
-
37549043217
-
Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis
-
Sanjuan, M. A. et al. Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis. Nature 450, 1253-1257 (2007).
-
(2007)
Nature
, vol.450
, pp. 1253-1257
-
-
Sanjuan, M.A.1
-
48
-
-
84923000335
-
Type i interferons in infectious disease
-
McNab, F. et al. Type I interferons in infectious disease. Nat Rev Immunol. 15, 87-103 (2015).
-
(2015)
Nat Rev Immunol.
, vol.15
, pp. 87-103
-
-
McNab, F.1
-
49
-
-
80053303830
-
Autophagy and cytokines
-
Harris, J. Autophagy and cytokines. Cytokine 56, 140-144 (2011).
-
(2011)
Cytokine
, vol.56
, pp. 140-144
-
-
Harris, J.1
-
50
-
-
84877610008
-
Bacterial subversion of host innate immune pathways
-
Baxt, L. A., Garza-Mayers, A. C., Goldberg, M. B. Bacterial subversion of host innate immune pathways. Science 340, 697-701 (2013).
-
(2013)
Science
, vol.340
, pp. 697-701
-
-
Baxt, L.A.1
Garza-Mayers, A.C.2
Goldberg, M.B.3
-
51
-
-
34548067415
-
Listeria monocytogenes evades killing by autophagy during colonization of host cells
-
Birmingham, C. L. et al. Listeria monocytogenes evades killing by autophagy during colonization of host cells. Autophagy 3, 442-451 (2007).
-
(2007)
Autophagy
, vol.3
, pp. 442-451
-
-
Birmingham, C.L.1
-
52
-
-
84892678766
-
Bacteria-autophagy interplay: A battle for survival
-
Huang, J., Brumell, J. H. Bacteria-autophagy interplay: a battle for survival. Nat Rev Microbiol 12, 101-114 (2014).
-
(2014)
Nat Rev Microbiol
, vol.12
, pp. 101-114
-
-
Huang, J.1
Brumell, J.H.2
-
53
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
Nakahira, K. et al. Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat Immunol 12, 222-230 (2011).
-
(2011)
Nat Immunol
, vol.12
, pp. 222-230
-
-
Nakahira, K.1
-
54
-
-
82455210868
-
Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1beta
-
Dupont, N. et al. Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1beta. EMBO J 30, 4701-4711 (2011).
-
(2011)
EMBO J
, vol.30
, pp. 4701-4711
-
-
Dupont, N.1
-
55
-
-
84965107840
-
Inflammasome Complexes: Emerging Mechanisms and Effector Functions
-
Rathinam, V. A., Fitzgerald, K. A. Inflammasome Complexes: Emerging Mechanisms and Effector Functions. Cell 165, 792-800 (2016).
-
(2016)
Cell
, vol.165
, pp. 792-800
-
-
Rathinam, V.A.1
Fitzgerald, K.A.2
-
56
-
-
84860247190
-
Revisiting the role of the granuloma in tuberculosis
-
Ramakrishnan, L. Revisiting the role of the granuloma in tuberculosis. Nat Rev Immunol 12, 352-366 (2012).
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 352-366
-
-
Ramakrishnan, L.1
-
57
-
-
84943148713
-
Macrophage supply and demand at the core of the necrotic Granuloma
-
Randolph, G. J. Macrophage Supply and Demand at the Core of the Necrotic Granuloma. Cell Host Microbe 18, 3-4 (2015).
-
(2015)
Cell Host Microbe
, vol.18
, pp. 3-4
-
-
Randolph, G.J.1
-
58
-
-
13044272898
-
Influence of the high density lipoprotein receptor SR-BI on reproductive and cardiovascular pathophysiology
-
Trigatti, B. et al. Influence of the high density lipoprotein receptor SR-BI on reproductive and cardiovascular pathophysiology. Proc Natl Acad Sci USA 96, 9322-9327 (1999).
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 9322-9327
-
-
Trigatti, B.1
-
59
-
-
0030729724
-
A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type i reveals its key role in HDL metabolism
-
Rigotti, A. et al. A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism. Proc Natl Acad Sci USA 94, 12610-12615 (1997).
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 12610-12615
-
-
Rigotti, A.1
|