In non-transformed cells Bak activates upon loss of anti-apoptotic Bcl-XL and Mcl-1 but in the absence of active BH3-only proteins

Cell Death and Disease

Volumn 6, Issue 11, 2015, Pages

  Senft, D ^a   Weber, A ^b   Saathoff, F ^a   Berking, C ^a   Heppt, M V ^a   Kammerbauer, C ^a   Rothenfusser, S ^a   Kellner, S ^a   Kurgyis, Z ^a,c   Besch, R ^a   Hacker G ^b  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITY OF SZEGED   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TUBULIN; BH3 PROTEIN; BIM PROTEIN; CASPASE 3; CASPASE 9; CYTOCHROME C; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; PROTEIN MCL 1; PROTEIN NOXA; PUMA PROTEIN; SMALL INTERFERING RNA; BAK1 PROTEIN, HUMAN; BCL2L1 PROTEIN, HUMAN; C22ORF29 PROTEIN, HUMAN; MCL1 PROTEIN, HUMAN; PROTEIN BCL X;

ANIMAL CELL; APOPTOSIS; ARTICLE; CAPILLARY ENDOTHELIAL CELL; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; FEMALE; FIBROBLAST; HELA CELL LINE; HUMAN; HUMAN CELL; KERATINOCYTE; MITOCHONDRION; MOUSE; NON-TRANSFORMED CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RNA INTERFERENCE; TRANSCRIPTION INITIATION; ANIMAL; CELL CULTURE; DEFICIENCY; ENDOTHELIUM CELL; GENETIC TRANSFECTION; METABOLISM; PHYSIOLOGY; ULTRASTRUCTURE;

ANIMALS; APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-X PROTEIN; CELL SURVIVAL; CELLS, CULTURED; ENDOTHELIAL CELLS; FIBROBLASTS; HUMANS; KERATINOCYTES; MICE; MITOCHONDRIA; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; PROTO-ONCOGENE PROTEINS C-BCL-2; TRANSFECTION;

EID: 84989861132     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2015.341     Document Type: Article

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