Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 40, 2016, Pages 11306-11311

  Oshima, Koichi ^a   Khiabanian, Hossein ^a,b   Da Silva Almeida, Ana C ^a   Tzoneva, Gannie ^a   Abate, Francesco ^a   Ambesi Impiombato, Alberto ^a   Sanchez Martin, Marta ^a   Carpenter, Zachary ^a   Penson, Alex ^a   Perez Garcia, Arianne ^a   Eckert, Cornelia ^c,d   Nicolas, Concepción ^e   Balbin, Milagros ^f   Sulis, Maria Luisa ^g   Kato, Motohiro ^h   Koh, Katsuyoshi ^h   Paganin, Maddalena ⁱ   Basso, Giuseppe ⁱ   Gastier Foster, Julie M ^j,k,l   Devidas, Meenakshi ^m   Loh, Mignon L ^n,o   Kirschner Schwabe, Renate ^c,d   Palomero, Teresa ^a,g   Rabadan, Raul ^a   Ferrando, Adolfo A ^a,g   more..

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^e HOSPITAL UNIVERSITARIO CENTRAL DE ASTURIAS   (Spain)

^f DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

^g NewYork Presbyterian Hospital   (United States)

^h SAITAMA CHILDREN'S MEDICAL CENTER   (Japan)

ⁱ UNIVERSITY OF PADOVA   (Italy)

^j NATIONWIDE CHILDREN S HOSPITAL   (United States)

^k THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^l CHILDREN S ONCOLOGY GROUP   (United States)

^m UNIVERSITY OF FLORIDA   (United States)

ⁿ UNIVERSITY OF CALIFORNIA   (United States)

^o UNIVERSITY OF CALIFORNIA   (United States)

more..

Author keywords

Acute lymphoblastic leukemia; Chemotherapy resistance; Genome sequencing; Relapsed leukemia

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; CD135 ANTIGEN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; DNA; EPHRIN RECEPTOR A3; JANUS KINASE 1; JANUS KINASE 2; JANUS KINASE 3; METHOTREXATE; MITOGEN ACTIVATED PROTEIN KINASE; N (2,3 DIHYDROXYPROPOXY) 3,4 DIFLUORO 2 (2 FLUORO 4 IODOANILINO)BENZAMIDE; NOTCH1 RECEPTOR; PROTEIN P53; PROTEIN TYROSINE PHOSPHATASE SHP 2; TRANSCRIPTION FACTOR RUNX1; VINCRISTINE; WT1 PROTEIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BCL11B GENE; CACNA1H GENE; CANCER GROWTH; CHILDHOOD LEUKEMIA; CLONAL EVOLUTION; CNOT3 GENE; CONTROLLED STUDY; DNM2 GENE; DRUG RESISTANCE; DRUG RESPONSE; FBXW7 GENE; GAIN OF FUNCTION MUTATION; GENE MUTATION; HTR3A GENE; HUMAN; HUMAN CELL; IL17RA GENE; LEUKEMIA RELAPSE; LYMPHOBLAST; MED12 GENE; MOLECULAR CLONING; MOUSE; NONHUMAN; ONCOGENE; ONCOGENE K RAS; ONCOGENE N RAS; ONCOGENE RAS; PHF6 GENE; PRIORITY JOURNAL; RPGR GENE; RPL10 GENE; SEQUENCE ANALYSIS; SHROOM3 GENE; SOMATIC MUTATION; TENM3 GENE; USP7 GENE; USP9X GENE; VIRUS ONCOGENE; ZFHX3 GENE; DRUG EFFECTS; GENETICS; MUTATION; NUCLEOTIDE SEQUENCE; PATHOLOGY; TUMOR CELL LINE;

BASE SEQUENCE; CELL LINE, TUMOR; CLONAL EVOLUTION; DRUG RESISTANCE, NEOPLASM; GENES, RAS; HUMANS; METHOTREXATE; MUTATION; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; VINCRISTINE;

EID: 84989813801     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1608420113     Document Type: Article

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