Ninety-day toxicity and single-dose toxicokinetics study of alpha-glycosyl isoquercitrin in Sprague-Dawley rats

Food and Chemical Toxicology

Volumn 97, Issue , 2016, Pages 354-366

  Nyska, Abraham ^a   Hayashi, Shim mo ^b   Koyanagi, Mihoko ^b   Davis, Jeffrey P ^c   Jokinen, Micheal P ^c   Ramot, Yuval ^d   Maronpot, Robert R ^e  

^a TEL AVIV UNIVERSITY   (Israel)

^b SAN EI GEN F F I INC   (Japan)

^c INTEGRATED LABORATORY SYSTEMS   (United States)

^d HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^e Maronpot Consulting LLC   (United States)

Author keywords

AGIQ; Alpha glycosyl isoquercitrin; EMIQ; Flavonol; Isoquercitrin; Quercetin; Safety; Sprague Dawley; Toxicity; Toxicokinetics

Indexed keywords

ALPHA GLYCOSYL ISOQUERCITRIN; ISOQUERCITRIN; QUERCETIN; QUERCETIN GLUCURONIDE; UNCLASSIFIED DRUG; GLYCOSIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BONE DISCOLORATION; COLOR; CONTROLLED STUDY; DIETARY INTAKE; FEMALE; LIMIT OF QUANTITATION; MALE; MICROSCOPY; NONHUMAN; ORGAN WEIGHT; RAT; TOXICOKINETICS; ANALOGS AND DERIVATIVES; ANIMAL; BLOOD EXAMINATION; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; MOTOR ACTIVITY; ORAL DRUG ADMINISTRATION; ORGAN SIZE; SPRAGUE DAWLEY RAT;

ADMINISTRATION, ORAL; ANIMALS; BODY WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GLYCOSIDES; HEMATOLOGIC TESTS; MALE; MOTOR ACTIVITY; ORGAN SIZE; QUERCETIN; RATS; RATS, SPRAGUE-DAWLEY; TOXICOKINETICS;

EID: 84989813020     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2016.09.030     Document Type: Article

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