Antioxidant enzymatically modified isoquercitrin suppresses the development of liver preneoplastic lesions in rats induced by β-naphthoflavone

Toxicology

Volumn 268, Issue 3, 2010, Pages 213-218

  Shimada, Yuko ^a   Dewa, Yasuaki ^a   Ichimura, Ryohei ^a   Suzuki, Terumasa ^a   Mizukami, Sayaka ^a   Hayashi, Shim mo ^b   Shibutani, Makoto ^a   Mitsumori, Kunitoshi ^a  

^a TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

^b SAN EI GEN F F I INC   (Japan)

Author keywords

Naphthoflavone; Enzymatically modified isoquercitrin; Hepatocellular tumor promotion; Inflammation; Oxidative stress

Indexed keywords

BETA NAPHTHOFLAVONE; CYCLOOXYGENASE 2; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE P1; I KAPPA B KINASE ALPHA; ISOQUERCITRIN; MESSENGER RNA; SERINE PROTEINASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CANCER PREVENTION; CONTROLLED STUDY; GENE EXPRESSION; LIVER CANCER; LIVER PROTECTION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; RAT; TUMOR PROMOTION;

ANIMALS; ANTICARCINOGENIC AGENTS; ANTIOXIDANTS; BETA-NAPHTHOFLAVONE; CONNECTIVE TISSUE; CYCLOOXYGENASE 2; GLUTATHIONE PEROXIDASE; IMMUNOHISTOCHEMISTRY; LIVER NEOPLASMS, EXPERIMENTAL; MALE; PRECANCEROUS CONDITIONS; QUERCETIN; RATS; RATS, INBRED F344; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

RATTUS;

EID: 76749146400     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2009.12.019     Document Type: Article

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