-
1
-
-
16844381831
-
Mechanisms of B-cell lymphoma pathogenesis
-
Kuppers R. Mechanisms of B-cell lymphoma pathogenesis. Nat Rev Cancer 2005; 5: 251-262.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 251-262
-
-
Kuppers, R.1
-
2
-
-
0036884169
-
Lymphoid malignancies: The dark side of B-cell differentiation
-
Shaffer AL, Rosenwald A, Staudt LM. Lymphoid malignancies: the dark side of B-cell differentiation. Nat Rev Immunol 2002; 2: 920-932.
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 920-932
-
-
Shaffer, A.L.1
Rosenwald, A.2
Staudt, L.M.3
-
3
-
-
0034598746
-
Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
-
Alizadeh AA, Eisen MB, Davis RE, Ma C, Lossos IS, Rosenwald A et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 2000; 403: 503-511.
-
(2000)
Nature
, vol.403
, pp. 503-511
-
-
Alizadeh, A.A.1
Eisen, M.B.2
Davis, R.E.3
Ma, C.4
Lossos, I.S.5
Rosenwald, A.6
-
4
-
-
84880202725
-
The genetic basis of diffuse large B-cell lymphoma
-
Pasqualucci L. The genetic basis of diffuse large B-cell lymphoma. Curr Opin Hematol 2013; 20: 336-344.
-
(2013)
Curr Opin Hematol
, vol.20
, pp. 336-344
-
-
Pasqualucci, L.1
-
5
-
-
84859213922
-
Burkitt's lymphoma
-
Molyneux EM, Rochford R, Griffin B, Newton R, Jackson G, Menon G et al. Burkitt's lymphoma. Lancet 2012; 379: 1234-1244.
-
(2012)
Lancet
, vol.379
, pp. 1234-1244
-
-
Molyneux, E.M.1
Rochford, R.2
Griffin, B.3
Newton, R.4
Jackson, G.5
Menon, G.6
-
6
-
-
0017103895
-
Non-endemic Burktt's lymphoma - A B-cell tumor related to germinal centers
-
Mann RB, Jaffe ES, Braylan RC, Nanba K, Frank MM, Ziegler JL et al. Non-endemic Burktt's lymphoma - A B-cell tumor related to germinal centers. N Engl J Med 1976; 195: 687-691.
-
(1976)
N Engl J Med
, vol.195
, pp. 687-691
-
-
Mann, R.B.1
Jaffe, E.S.2
Braylan, R.C.3
Nanba, K.4
Frank, M.M.5
Ziegler, J.L.6
-
7
-
-
84867051939
-
Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics
-
Schmitz R, Young RM, Ceribelli M, Jhavar S, Xiao W, Zhang M et al. Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics. Nature 2012; 490: 116-120.
-
(2012)
Nature
, vol.490
, pp. 116-120
-
-
Schmitz, R.1
Young, R.M.2
Ceribelli, M.3
Jhavar, S.4
Xiao, W.5
Zhang, M.6
-
8
-
-
1042290351
-
The SWI/SNF complex-chromatin and cancer
-
Roberts CW, Orkin SH. The SWI/SNF complex-chromatin and cancer. Nat Rev Cancer 2004; 4: 133-142.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 133-142
-
-
Roberts, C.W.1
Orkin, S.H.2
-
9
-
-
84876460347
-
Hierarchy in somatic mutations arising during genomic evolution and progression of follicular lymphoma
-
Green MR, Gentles AJ, Nair RV, Irish JM, Kihira S, Liu CL et al. Hierarchy in somatic mutations arising during genomic evolution and progression of follicular lymphoma. Blood 2013; 121: 1604-1611.
-
(2013)
Blood
, vol.121
, pp. 1604-1611
-
-
Green, M.R.1
Gentles, A.J.2
Nair, R.V.3
Irish, J.M.4
Kihira, S.5
Liu, C.L.6
-
10
-
-
84924308788
-
Mutations in early follicular lymphoma progenitors are associated with suppressed antigen presentation
-
Green MR, Kihira S, Liu CL, Nair RV, Salari R, Gentles AJ et al. Mutations in early follicular lymphoma progenitors are associated with suppressed antigen presentation. Proc Natl Acad Sci USA 2015; 112: E1116-E1125.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. E1116-E1125
-
-
Green, M.R.1
Kihira, S.2
Liu, C.L.3
Nair, R.V.4
Salari, R.5
Gentles, A.J.6
-
11
-
-
75749124332
-
Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
-
Morin RD, Johnson NA, Severson TM, Mungall AJ, An J, Goya R et al. Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin. Nat Genet 2010; 42: 181-185.
-
(2010)
Nat Genet
, vol.42
, pp. 181-185
-
-
Morin, R.D.1
Johnson, N.A.2
Severson, T.M.3
Mungall, A.J.4
An, J.5
Goya, R.6
-
12
-
-
80052029516
-
Frequent mutation of histone-modifying genes in non-hodgkin lymphoma
-
Morin RD, Mendez-Lago M, Mungall AJ, Goya R, Mungall KL, Corbett RD et al. Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma. Nature 2011; 476: 298-303.
-
(2011)
Nature
, vol.476
, pp. 298-303
-
-
Morin, R.D.1
Mendez-Lago, M.2
Mungall, A.J.3
Goya, R.4
Mungall, K.L.5
Corbett, R.D.6
-
13
-
-
84886290682
-
Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing
-
Morin RD, Mungall K, Pleasance E, Mungall AJ, Goya R, Huff RD et al. Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing. Blood 2013; 122: 1256-1265.
-
(2013)
Blood
, vol.122
, pp. 1256-1265
-
-
Morin, R.D.1
Mungall, K.2
Pleasance, E.3
Mungall, A.J.4
Goya, R.5
Huff, R.D.6
-
14
-
-
84895815322
-
Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma
-
Okosun J, Bodor C, Wang J, Araf S, Yang CY, Pan C et al. Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma. Nat Genet 2014; 46: 176-181.
-
(2014)
Nat Genet
, vol.46
, pp. 176-181
-
-
Okosun, J.1
Bodor, C.2
Wang, J.3
Araf, S.4
Yang, C.Y.5
Pan, C.6
-
15
-
-
79952430906
-
Inactivating mutations of acetyltransferase genes in B-cell lymphoma
-
Pasqualucci L, Dominguez-Sola D, Chiarenza A, Fabbri G, Grunn A, Trifonov V et al. Inactivating mutations of acetyltransferase genes in B-cell lymphoma. Nature 2011; 471: 189-195.
-
(2011)
Nature
, vol.471
, pp. 189-195
-
-
Pasqualucci, L.1
Dominguez-Sola, D.2
Chiarenza, A.3
Fabbri, G.4
Grunn, A.5
Trifonov, V.6
-
16
-
-
84892553514
-
Genetics of follicular lymphoma transformation
-
Pasqualucci L, Khiabanian H, Fangazio M, Vasishtha M, Messina M, Holmes AB et al. Genetics of follicular lymphoma transformation. Cell Rep 2014; 6: 130-140.
-
(2014)
Cell Rep
, vol.6
, pp. 130-140
-
-
Pasqualucci, L.1
Khiabanian, H.2
Fangazio, M.3
Vasishtha, M.4
Messina, M.5
Holmes, A.B.6
-
17
-
-
84872856782
-
Genetic heterogeneity of diffuse large B-cell lymphoma
-
Zhang J, Grubor V, Love CL, Banerjee A, Richards KL, Mieczkowski PA et al. Genetic heterogeneity of diffuse large B-cell lymphoma. Proc Natl Acad Sci USA 2013; 110: 1398-1403.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 1398-1403
-
-
Zhang, J.1
Grubor, V.2
Love, C.L.3
Banerjee, A.4
Richards, K.L.5
Mieczkowski, P.A.6
-
18
-
-
84870538715
-
The genetic landscape of mutations in Burkitt lymphoma
-
Love C, Sun Z, Jima D, Li G, Zhang J, Miles R et al. The genetic landscape of mutations in Burkitt lymphoma. Nat Genet 2012; 44: 1321-1325.
-
(2012)
Nat Genet
, vol.44
, pp. 1321-1325
-
-
Love, C.1
Sun, Z.2
Jima, D.3
Li, G.4
Zhang, J.5
Miles, R.6
-
19
-
-
27644589675
-
The diverse functions of histone lysine methylation
-
Martin C, Zhang Y. The diverse functions of histone lysine methylation. Nat Rev Mol Cell Biol 2005; 6: 838-849.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 838-849
-
-
Martin, C.1
Zhang, Y.2
-
20
-
-
84870375316
-
Histone lysine methylation dynamics: Establishment, regulation, and biological impact
-
Black JC, Van Rechem C, Whetstine JR. Histone lysine methylation dynamics: establishment, regulation, and biological impact. Mol Cell 2012; 48: 491-507.
-
(2012)
Mol Cell
, vol.48
, pp. 491-507
-
-
Black, J.C.1
Van Rechem, C.2
Whetstine, J.R.3
-
21
-
-
35548934558
-
MLL translocations, histone modifications and Leukaemia stem-cell development
-
Krivtsov AV, Armstrong SA. MLL translocations, histone modifications and leukaemia stem-cell development. Nat Rev Cancer 2007; 7: 823-833.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 823-833
-
-
Krivtsov, A.V.1
Armstrong, S.A.2
-
22
-
-
84892683106
-
Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas mll1 is redundant
-
Denissov S, Hofemeister H, Marks H, Kranz A, Ciotta G, Singh S et al. Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant. Development 2014; 141: 526-537.
-
(2014)
Development
, vol.141
, pp. 526-537
-
-
Denissov, S.1
Hofemeister, H.2
Marks, H.3
Kranz, A.4
Ciotta, G.5
Singh, S.6
-
23
-
-
77956642100
-
Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome
-
Ng SB, Bigham AW, Buckingham KJ, Hannibal MC, McMillin MJ, Gildersleeve HI et al. Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome. Nat Genet 2010; 42: 790-793.
-
(2010)
Nat Genet
, vol.42
, pp. 790-793
-
-
Ng, S.B.1
Bigham, A.W.2
Buckingham, K.J.3
Hannibal, M.C.4
McMillin, M.J.5
Gildersleeve, H.I.6
-
24
-
-
84867908690
-
Global identification of MLL2-targeted loci reveals MLL2's role in diverse signaling pathways
-
Guo C, Chang CC, Wortham M, Chen LH, Kernagis DN, Qin X et al. Global identification of MLL2-targeted loci reveals MLL2's role in diverse signaling pathways. Proc Natl Acad Sci USA 2012; 109: 17603-17608.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 17603-17608
-
-
Guo, C.1
Chang, C.C.2
Wortham, M.3
Chen, L.H.4
Kernagis, D.N.5
Qin, X.6
-
25
-
-
79955494277
-
Histone methylation by PRC2 is inhibited by active chromatin marks
-
Schmitges FW, Prusty AB, Faty M, Stutzer A, Lingaraju GM, Aiwazian J et al. Histone methylation by PRC2 is inhibited by active chromatin marks. Mol Cell 2011; 42: 330-341.
-
(2011)
Mol Cell
, vol.42
, pp. 330-341
-
-
Schmitges, F.W.1
Prusty, A.B.2
Faty, M.3
Stutzer, A.4
Lingaraju, G.M.5
Aiwazian, J.6
-
26
-
-
51649111684
-
Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways
-
Lenz G, Wright GW, Emre NC, Kohlhammer H, Dave SS, Davis RE et al. Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways. Proc Natl Acad Sci USA 2008; 105: 13520-13525.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13520-13525
-
-
Lenz, G.1
Wright, G.W.2
Emre, N.C.3
Kohlhammer, H.4
Dave, S.S.5
Davis, R.E.6
-
27
-
-
19044396946
-
Human ING1 proteins differentially regulate histone acetylation
-
Vieyra D, Loewith R, Scott M, Bonnefin P, Boisvert FM, Cheema P et al. Human ING1 proteins differentially regulate histone acetylation. J Biol Chem 2002; 277: 29832-29839.
-
(2002)
J Biol Chem
, vol.277
, pp. 29832-29839
-
-
Vieyra, D.1
Loewith, R.2
Scott, M.3
Bonnefin, P.4
Boisvert, F.M.5
Cheema, P.6
-
28
-
-
0034780285
-
Role of an ING1 growth regulator in transcriptional activation and targeted histone acetylation by the NuA4 complex
-
Nourani A, Doyon Y, Utley RT, Allard S, Lane WS, Cote J. Role of an ING1 growth regulator in transcriptional activation and targeted histone acetylation by the NuA4 complex. Mol Cell Biol 2001; 21: 7629-7640.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 7629-7640
-
-
Nourani, A.1
Doyon, Y.2
Utley, R.T.3
Allard, S.4
Lane, W.S.5
Cote, J.6
-
29
-
-
84877815031
-
EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation
-
Beguelin W, Popovic R, Teater M, Jiang Y, Bunting KL, Rosen M et al. EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation. Cancer Cell 2013; 23: 677-692.
-
(2013)
Cancer Cell
, vol.23
, pp. 677-692
-
-
Beguelin, W.1
Popovic, R.2
Teater, M.3
Jiang, Y.4
Bunting, K.L.5
Rosen, M.6
-
30
-
-
33846148370
-
PRB family proteins are required for H3K27 trimethylation and polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene
-
Kotake Y, Cao R, Viatour P, Sage J, Zhang Y, Xiong Y. pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene. Genes Dev 2007; 21: 49-54.
-
(2007)
Genes Dev
, vol.21
, pp. 49-54
-
-
Kotake, Y.1
Cao, R.2
Viatour, P.3
Sage, J.4
Zhang, Y.5
Xiong, Y.6
-
31
-
-
3442876431
-
Distinct expression patterns of polycomb oncoproteins and their binding partners during the germinal center reaction
-
van Galen JC, Dukers DF, Giroth C, Sewalt RG, Otte AP, Meijer CJ et al. Distinct expression patterns of polycomb oncoproteins and their binding partners during the germinal center reaction. Eur J Immunol 2004; 34: 1870-1881.
-
(2004)
Eur J Immunol
, vol.34
, pp. 1870-1881
-
-
Van Galen, J.C.1
Dukers, D.F.2
Giroth, C.3
Sewalt, R.G.4
Otte, A.P.5
Meijer, C.J.6
-
32
-
-
77955085750
-
Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders
-
Ernst T, Chase AJ, Score J, Hidalgo-Curtis CE, Bryant C, Jones AV et al. Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders. Nat Genet 2010; 42: 722-726.
-
(2010)
Nat Genet
, vol.42
, pp. 722-726
-
-
Ernst, T.1
Chase, A.J.2
Score, J.3
Hidalgo-Curtis, C.E.4
Bryant, C.5
Jones, A.V.6
-
33
-
-
84856747744
-
Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic Leukemia
-
Ntziachristos P, Tsirigos A, Van Vlierberghe P, Nedjic J, Trimarchi T, Flaherty MS et al. Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia. Nat Med 2012; 18: 298-301.
-
(2012)
Nat Med
, vol.18
, pp. 298-301
-
-
Ntziachristos, P.1
Tsirigos, A.2
Van Vlierberghe, P.3
Nedjic, J.4
Trimarchi, T.5
Flaherty, M.S.6
-
34
-
-
79954435405
-
EZH2 Y641 mutations in follicular lymphoma
-
Bodor C, O'Riain C, Wrench D, Matthews J, Iyengar S, Tayyib H et al. EZH2 Y641 mutations in follicular lymphoma. Leukemia 2011; 25: 726-729.
-
(2011)
Leukemia
, vol.25
, pp. 726-729
-
-
Bodor, C.1
O'Riain, C.2
Wrench, D.3
Matthews, J.4
Iyengar, S.5
Tayyib, H.6
-
35
-
-
84863165348
-
Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)
-
McCabe MT, Graves AP, Ganji G, Diaz E, Halsey WS, Jiang Y et al. Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27). Proc Natl Acad Sci USA 2012; 109: 2989-2994.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 2989-2994
-
-
McCabe, M.T.1
Graves, A.P.2
Ganji, G.3
Diaz, E.4
Halsey, W.S.5
Jiang, Y.6
-
36
-
-
79952167230
-
Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation
-
Yap DB, Chu J, Berg T, Schapira M, Cheng SW, Moradian A et al. Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation. Blood 2011; 117: 2451-2459.
-
(2011)
Blood
, vol.117
, pp. 2451-2459
-
-
Yap, D.B.1
Chu, J.2
Berg, T.3
Schapira, M.4
Cheng, S.W.5
Moradian, A.6
-
37
-
-
78650454078
-
Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas
-
Sneeringer CJ, Scott MP, Kuntz KW, Knutson SK, Pollock RM, Richon VM et al. Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas. Proc Natl Acad Sci USA 2010; 107: 20980-20985.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 20980-20985
-
-
Sneeringer, C.J.1
Scott, M.P.2
Kuntz, K.W.3
Knutson, S.K.4
Pollock, R.M.5
Richon, V.M.6
-
38
-
-
84870308969
-
EZH2 generates a methyl degron that is recognized by the DCAF1/DDB1/CUL4 E3 ubiquitin ligase complex
-
Lee JM, Lee JS, Kim H, Kim K, Park H, Kim JY et al. EZH2 generates a methyl degron that is recognized by the DCAF1/DDB1/CUL4 E3 ubiquitin ligase complex. Mol Cell 2012; 48: 572-586.
-
(2012)
Mol Cell
, vol.48
, pp. 572-586
-
-
Lee, J.M.1
Lee, J.S.2
Kim, H.3
Kim, K.4
Park, H.5
Kim, J.Y.6
-
39
-
-
21044451441
-
Polycomb group protein ezh2 controls actin polymerization and cell signaling
-
Su IH, Dobenecker MW, Dickinson E, Oser M, Basavaraj A, Marqueron R et al. Polycomb group protein ezh2 controls actin polymerization and cell signaling. Cell 2005; 121: 425-436.
-
(2005)
Cell
, vol.121
, pp. 425-436
-
-
Su, I.H.1
Dobenecker, M.W.2
Dickinson, E.3
Oser, M.4
Basavaraj, A.5
Marqueron, R.6
-
40
-
-
84870573126
-
EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations
-
McCabe MT, Ott HM, Ganji G, Korenchuk S, Thompson C, Van Aller GS et al. EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations. Nature 2012; 492: 108-112.
-
(2012)
Nature
, vol.492
, pp. 108-112
-
-
McCabe, M.T.1
Ott, H.M.2
Ganji, G.3
Korenchuk, S.4
Thompson, C.5
Van Aller, G.S.6
-
41
-
-
84867632489
-
A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells
-
Knutson SK, Wigle TJ, Warholic NM, Sneeringer CJ, Allain CJ, Klaus CR et al. A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells. Nat Chemi Biol 2012; 8: 890-896.
-
(2012)
Nat Chemi Biol
, vol.8
, pp. 890-896
-
-
Knutson, S.K.1
Wigle, T.J.2
Warholic, N.M.3
Sneeringer, C.J.4
Allain, C.J.5
Klaus, C.R.6
-
42
-
-
84871841675
-
Selective inhibition of ezh2 by a small molecule inhibitor blocks tumor cells proliferation
-
Qi W, Chan H, Teng L, Li L, Chuai S, Zhang R et al. Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation. Proc Natl Acad Sci USA 2012; 109: 21360-21365.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 21360-21365
-
-
Qi, W.1
Chan, H.2
Teng, L.3
Li, L.4
Chuai, S.5
Zhang, R.6
-
44
-
-
33744495991
-
Global transcriptional coactivators CREB-binding protein and p300 are highly essential collectively but not individually in peripheral B cells
-
Xu W, Fukuyama T, Ney PA, Wang D, Rehg J, Boyd K et al. Global transcriptional coactivators CREB-binding protein and p300 are highly essential collectively but not individually in peripheral B cells. Blood 2006; 107: 4407-4416.
-
(2006)
Blood
, vol.107
, pp. 4407-4416
-
-
Xu, W.1
Fukuyama, T.2
Ney, P.A.3
Wang, D.4
Rehg, J.5
Boyd, K.6
-
45
-
-
0029022770
-
Rubinstein-taybi syndrome caused by mutations in the transcriptional coactivator CBP
-
Petrij F, Giles RH, Dauwerse HG, Saris JJ, Hennekam RC, Masuno M et al. Rubinstein-Taybi syndrome caused by mutations in the transcriptional coactivator CBP. Nature 1995; 376: 348-351.
-
(1995)
Nature
, vol.376
, pp. 348-351
-
-
Petrij, F.1
Giles, R.H.2
Dauwerse, H.G.3
Saris, J.J.4
Hennekam, R.C.5
Masuno, M.6
-
46
-
-
79952381408
-
CREBBP mutations in relapsed acute lymphoblastic Leukaemia
-
Mullighan CG, Zhang J, Kasper LH, Lerach S, Payne-Turner D, Phillips LA et al. CREBBP mutations in relapsed acute lymphoblastic leukaemia. Nature 2011; 471: 235-239.
-
(2011)
Nature
, vol.471
, pp. 235-239
-
-
Mullighan, C.G.1
Zhang, J.2
Kasper, L.H.3
Lerach, S.4
Payne-Turner, D.5
Phillips, L.A.6
-
47
-
-
0034913587
-
CIITA coordinates multiple histone acetylation modifications at the HLA-DRA promoter
-
Beresford GW, Boss JM. CIITA coordinates multiple histone acetylation modifications at the HLA-DRA promoter. Nat Immunol 2001; 2: 652-657.
-
(2001)
Nat Immunol
, vol.2
, pp. 652-657
-
-
Beresford, G.W.1
Boss, J.M.2
-
48
-
-
0031773473
-
Involvement of CREB binding protein in expression of major histocompatibility complex class II genes via interaction with the class II transactivator
-
Kretsovali A, Agalioti T, Spilianakis C, Tzortzakaki E, Merika M, Papamatheakis J. Involvement of CREB binding protein in expression of major histocompatibility complex class II genes via interaction with the class II transactivator. Mol Cell Biol 1998; 18: 6777-6783.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 6777-6783
-
-
Kretsovali, A.1
Agalioti, T.2
Spilianakis, C.3
Tzortzakaki, E.4
Merika, M.5
Papamatheakis, J.6
-
49
-
-
0032937881
-
Interactions between the class II transactivator and CREB binding protein increase transcription of major histocompatibility complex class II genes
-
Fontes JD, Kanazawa S, Jean D, Peterlin BM. Interactions between the class II transactivator and CREB binding protein increase transcription of major histocompatibility complex class II genes. Mol Cell Biol 1999; 19: 941-947.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 941-947
-
-
Fontes, J.D.1
Kanazawa, S.2
Jean, D.3
Peterlin, B.M.4
-
50
-
-
0027495491
-
Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma
-
Ye BH, Lista F, Lo Coco F, Knowles DM, Offit K, Chaganti RS et al. Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma. Science 1993; 262: 747-750.
-
(1993)
Science
, vol.262
, pp. 747-750
-
-
Ye, B.H.1
Lista, F.2
Lo Coco, F.3
Knowles, D.M.4
Offit, K.5
Chaganti, R.S.6
-
51
-
-
84902097287
-
Transient expression of bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma
-
Green MR, Vicente-Duenas C, Romero-Camarero I, Long Liu C, Dai B, Gonzalez-Herrero I et al. Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma. Nat Commun 2014; 5: 3904.
-
(2014)
Nat Commun
, vol.5
, pp. 3904
-
-
Green, M.R.1
Vicente-Duenas, C.2
Romero-Camarero, I.3
Long Liu, C.4
Dai, B.5
Gonzalez-Herrero, I.6
-
52
-
-
0032531688
-
The LAZ3 (BCL-6) oncoprotein recruits a SMRT/mSIN3A/histone deacetylase containing complex to mediate transcriptional repression
-
Dhordain P, Lin RJ, Quief S, Lantoine D, Kerckaert JP, Evans RM et al. The LAZ3 (BCL-6) oncoprotein recruits a SMRT/mSIN3A/histone deacetylase containing complex to mediate transcriptional repression. Nucleic Acids Res 1998; 26: 4645-4651.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 4645-4651
-
-
Dhordain, P.1
Lin, R.J.2
Quief, S.3
Lantoine, D.4
Kerckaert, J.P.5
Evans, R.M.6
-
53
-
-
0037077227
-
Class II histone deacetylases are directly recruited by BCL6 transcriptional repressor
-
Lemercier C, Brocard MP, Puvion-Dutilleul F, Kao HY, Albagli O, Khochbin S. Class II histone deacetylases are directly recruited by BCL6 transcriptional repressor. J Biol Chem 2002; 277: 22045-22052.
-
(2002)
J Biol Chem
, vol.277
, pp. 22045-22052
-
-
Lemercier, C.1
Brocard, M.P.2
Puvion-Dutilleul, F.3
Kao, H.Y.4
Albagli, O.5
Khochbin, S.6
-
54
-
-
84879734857
-
Analysis of FOXO1 mutations in diffuse large B-cell lymphoma
-
Trinh DL, Scott DW, Morin RD, Mendez-Lago M, An J, Jones SJ et al. Analysis of FOXO1 mutations in diffuse large B-cell lymphoma. Blood 2013; 121: 3666-3674.
-
(2013)
Blood
, vol.121
, pp. 3666-3674
-
-
Trinh, D.L.1
Scott, D.W.2
Morin, R.D.3
Mendez-Lago, M.4
An, J.5
Jones, S.J.6
-
55
-
-
70350304558
-
PI3 kinase signals BCR-dependent mature B cell survival
-
Srinivasan L, Sasaki Y, Calado DP, Zhang B, Paik JH, DePinho RA et al. PI3 kinase signals BCR-dependent mature B cell survival. Cell 2009; 139: 573-586.
-
(2009)
Cell
, vol.139
, pp. 573-586
-
-
Srinivasan, L.1
Sasaki, Y.2
Calado, D.P.3
Zhang, B.4
Paik, J.H.5
DePinho, R.A.6
-
56
-
-
84896139490
-
FOXO1 transcription factor: A critical effector of the PI3K-AKT axis in B-cell development
-
Szydlowski M, Jablonska E, Juszczynski P. FOXO1 transcription factor: a critical effector of the PI3K-AKT axis in B-cell development. Int Rev Immunol 2014; 33: 146-157.
-
(2014)
Int Rev Immunol
, vol.33
, pp. 146-157
-
-
Szydlowski, M.1
Jablonska, E.2
Juszczynski, P.3
-
57
-
-
23844485211
-
Acetylation of foxo1 alters its DNA-binding ability and sensitivity to phosphorylation
-
Matsuzaki H, Daitoku H, Hatta M, Aoyama H, Yoshimochi K, Fukamizu A. Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation. Proc Natl Acad Sci USA 2005; 102: 11278-11283.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 11278-11283
-
-
Matsuzaki, H.1
Daitoku, H.2
Hatta, M.3
Aoyama, H.4
Yoshimochi, K.5
Fukamizu, A.6
-
58
-
-
0029130021
-
13q deletions in lymphoid malignancies
-
Liu Y, Hermanson M, Grander D, Merup M, Wu X, Heyman M et al. 13q deletions in lymphoid malignancies. Blood 1995; 86: 1911-1915.
-
(1995)
Blood
, vol.86
, pp. 1911-1915
-
-
Liu, Y.1
Hermanson, M.2
Grander, D.3
Merup, M.4
Wu, X.5
Heyman, M.6
-
59
-
-
84866028455
-
Integrative analysis reveals an outcome-associated and targetable pattern of p53 and cell cycle deregulation in diffuse large B cell lymphoma
-
Monti S, Chapuy B, Takeyama K, Rodig SJ, Hao Y, Yeda KT et al. Integrative analysis reveals an outcome-associated and targetable pattern of p53 and cell cycle deregulation in diffuse large B cell lymphoma. Cancer Cell 2012; 22: 359-372.
-
(2012)
Cancer Cell
, vol.22
, pp. 359-372
-
-
Monti, S.1
Chapuy, B.2
Takeyama, K.3
Rodig, S.J.4
Hao, Y.5
Yeda, K.T.6
-
60
-
-
0033017903
-
Frequent chromosome arm 13q deletion in aggressive non-hodgkin's lymphoma
-
Wada M, Okamura T, Okada M, Teramura M, Masuda M, Motoji T et al. Frequent chromosome arm 13q deletion in aggressive non-Hodgkin's lymphoma. Leukemia 1999; 13: 792-798.
-
(1999)
Leukemia
, vol.13
, pp. 792-798
-
-
Wada, M.1
Okamura, T.2
Okada, M.3
Teramura, M.4
Masuda, M.5
Motoji, T.6
-
61
-
-
0032484989
-
Retinoblastoma protein recruits histone deacetylase to repress transcription
-
Brehm A, Miska EA, McCance DJ, Reid JL, Bannister AJ, Kouzarides T. Retinoblastoma protein recruits histone deacetylase to repress transcription. Nature 1998; 391: 597-601.
-
(1998)
Nature
, vol.391
, pp. 597-601
-
-
Brehm, A.1
Miska, E.A.2
McCance, D.J.3
Reid, J.L.4
Bannister, A.J.5
Kouzarides, T.6
-
62
-
-
84897503371
-
Mutations in linker histone genes HIST1H1 B, C, D, and E; OCT2 (POU2F2); IRF8; and ARID1A underlying the pathogenesis of follicular lymphoma
-
Li H, Kaminski MS, Li Y, Yildiz M, Ouillette P, Jones S et al. Mutations in linker histone genes HIST1H1 B, C, D, and E; OCT2 (POU2F2); IRF8; and ARID1A underlying the pathogenesis of follicular lymphoma. Blood 2014; 123: 1487-1498.
-
(2014)
Blood
, vol.123
, pp. 1487-1498
-
-
Li, H.1
Kaminski, M.S.2
Li, Y.3
Yildiz, M.4
Ouillette, P.5
Jones, S.6
-
63
-
-
84857942952
-
Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing
-
Lohr JG, Stojanov P, Lawrence MS, Auclair D, Chapuy B, Sougnez C et al. Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing. Proc Natl Acad Sci USA 2012; 109: 3879-3884.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 3879-3884
-
-
Lohr, J.G.1
Stojanov, P.2
Lawrence, M.S.3
Auclair, D.4
Chapuy, B.5
Sougnez, C.6
-
64
-
-
0036165434
-
MEF2: A calcium-dependent regulator of cell division, differentiation and death
-
McKinsey TA, Zhang CL, Olson EN. MEF2: a calcium-dependent regulator of cell division, differentiation and death. Trends Biochem Sci 2002; 27: 40-47.
-
(2002)
Trends Biochem Sci
, vol.27
, pp. 40-47
-
-
McKinsey, T.A.1
Zhang, C.L.2
Olson, E.N.3
-
65
-
-
84901696903
-
A multicentre phase II study of vorinostat in patients with relapsed or refractory indolent B-cell non-hodgkin lymphoma and mantle cell lymphoma
-
Ogura M, Ando K, Suzuki T, Ishizawa K, Oh SY, Itoh K et al. A multicentre phase II study of vorinostat in patients with relapsed or refractory indolent B-cell non-Hodgkin lymphoma and mantle cell lymphoma. Br J Haematol 2014; 165: 768-776.
-
(2014)
Br J Haematol
, vol.165
, pp. 768-776
-
-
Ogura, M.1
Ando, K.2
Suzuki, T.3
Ishizawa, K.4
Oh, S.Y.5
Itoh, K.6
-
66
-
-
79952773321
-
Phase II study of vorinostat for treatment of relapsed or refractory indolent non-hodgkin's lymphoma and mantle cell lymphoma
-
Kirschbaum M, Frankel P, Popplewell L, Zain J, Delioukina M, Pullarkat V et al. Phase II study of vorinostat for treatment of relapsed or refractory indolent non-Hodgkin's lymphoma and mantle cell lymphoma. J Clin Oncol 2011; 29: 1198-1203.
-
(2011)
J Clin Oncol
, vol.29
, pp. 1198-1203
-
-
Kirschbaum, M.1
Frankel, P.2
Popplewell, L.3
Zain, J.4
Delioukina, M.5
Pullarkat, V.6
-
69
-
-
0028060515
-
The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest
-
Dunaief JL, Strober BE, Guha S, Khavari PA, Alin K, Luban J et al. The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest. Cell 1994; 79: 119-130.
-
(1994)
Cell
, vol.79
, pp. 119-130
-
-
Dunaief, J.L.1
Strober, B.E.2
Guha, S.3
Khavari, P.A.4
Alin, K.5
Luban, J.6
-
70
-
-
84901705081
-
The emerging roles of ARID1A in tumor suppression
-
Wu RC, Wang TL, Shih Ie M. The emerging roles of ARID1A in tumor suppression. Cancer Biol Ther 2014; 15: 655-664.
-
(2014)
Cancer Biol Ther
, vol.15
, pp. 655-664
-
-
Wu, R.C.1
Wang, T.L.2
Shih Ie, M.3
-
71
-
-
84867796875
-
Functional analysis of in-frame indel ARID1A mutations reveals new regulatory mechanisms of its tumor suppressor functions
-
Guan B, Gao M, Wu CH, Wang TL, Shih Ie M. Functional analysis of in-frame indel ARID1A mutations reveals new regulatory mechanisms of its tumor suppressor functions. Neoplasia 2012; 14: 986-993.
-
(2012)
Neoplasia
, vol.14
, pp. 986-993
-
-
Guan, B.1
Gao, M.2
Wu, C.H.3
Wang, T.L.4
Shih Ie, M.5
-
72
-
-
58149521944
-
Highly parallel identification of essential genes in cancer cells
-
Luo B, Cheung HW, Subramanian A, Sharifnia T, Okamoto M, Yang X et al. Highly parallel identification of essential genes in cancer cells. Proc Natl Acad Sci USA 2008; 105: 20380-20385.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 20380-20385
-
-
Luo, B.1
Cheung, H.W.2
Subramanian, A.3
Sharifnia, T.4
Okamoto, M.5
Yang, X.6
-
73
-
-
84891524428
-
The BRG1 chromatin remodeler regulates widespread changes in gene expression and cell proliferation during B cell activation
-
Holley DW, Groh BS, Wozniak G, Donohoe DR, Sun W, Godfrey V et al. The BRG1 chromatin remodeler regulates widespread changes in gene expression and cell proliferation during B cell activation. J Cell Physiol 2014; 229: 44-52.
-
(2014)
J Cell Physiol
, vol.229
, pp. 44-52
-
-
Holley, D.W.1
Groh, B.S.2
Wozniak, G.3
Donohoe, D.R.4
Sun, W.5
Godfrey, V.6
-
74
-
-
84896126029
-
ARID1B is a specific vulnerability in ARID1A-mutant cancers
-
Helming KC, Wang X, Wilson BG, Vazquez F, Haswell JR, Manchester HE et al. ARID1B is a specific vulnerability in ARID1A-mutant cancers. Nat Med 2014; 20: 251-254.
-
(2014)
Nat Med
, vol.20
, pp. 251-254
-
-
Helming, K.C.1
Wang, X.2
Wilson, B.G.3
Vazquez, F.4
Haswell, J.R.5
Manchester, H.E.6
-
75
-
-
84896898658
-
Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers
-
Hoffman GR, Rahal R, Buxton F, Xiang K, McAllister G, Frias E et al. Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers. Proc Natl Acad Sci USA 2014; 111: 3128-3133.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 3128-3133
-
-
Hoffman, G.R.1
Rahal, R.2
Buxton, F.3
Xiang, K.4
McAllister, G.5
Frias, E.6
-
76
-
-
44649186259
-
The histone H1 family: Specific members, specific functions?
-
Izzo A, Kamieniarz K, Schneider R. The histone H1 family: specific members, specific functions? Biol Chem 2008; 389: 333-343.
-
(2008)
Biol Chem
, vol.389
, pp. 333-343
-
-
Izzo, A.1
Kamieniarz, K.2
Schneider, R.3
-
77
-
-
14644388222
-
The dynamics of histone H1 function in chromatin
-
Bustin M, Catez F, Lim JH. The dynamics of histone H1 function in chromatin. Mol Cell 2005; 17: 617-620.
-
(2005)
Mol Cell
, vol.17
, pp. 617-620
-
-
Bustin, M.1
Catez, F.2
Lim, J.H.3
-
78
-
-
0038721220
-
H1 linker histones are essential for mouse development and affect nucleosome spacing in vivo
-
Fan Y, Nikitina T, Morin-Kensicki EM, Zhao J, Magnuson TR, Woodcock CL et al. H1 linker histones are essential for mouse development and affect nucleosome spacing in vivo. Mol Cell Biol 2003; 23: 4559-4572.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 4559-4572
-
-
Fan, Y.1
Nikitina, T.2
Morin-Kensicki, E.M.3
Zhao, J.4
Magnuson, T.R.5
Woodcock, C.L.6
-
79
-
-
29244449333
-
Histone H1 depletion in mammals alters global chromatin structure but causes specific changes in gene regulation
-
Fan Y, Nikitina T, Zhao J, Fleury TJ, Bhattacharyya R, Bouhassira EE et al. Histone H1 depletion in mammals alters global chromatin structure but causes specific changes in gene regulation. Cell 2005; 123: 1199-1212.
-
(2005)
Cell
, vol.123
, pp. 1199-1212
-
-
Fan, Y.1
Nikitina, T.2
Zhao, J.3
Fleury, T.J.4
Bhattacharyya, R.5
Bouhassira, E.E.6
-
80
-
-
0035166077
-
Individual somatic H1 subtypes are dispensable for mouse development even in mice lacking the H1(0) replacement subtype
-
Fan Y, Sirotkin A, Russell RG, Ayala J, Skoultchi AI. Individual somatic H1 subtypes are dispensable for mouse development even in mice lacking the H1(0) replacement subtype. Mol Cell Biol 2001; 21: 7933-7943.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 7933-7943
-
-
Fan, Y.1
Sirotkin, A.2
Russell, R.G.3
Ayala, J.4
Skoultchi, A.I.5
-
81
-
-
84864627631
-
Histone methyltransferase NSD2/MMSET mediates constitutive NF-kappaB signaling for cancer cell proliferation, survival, and tumor growth via a feed-forward loop
-
Yang P, Guo L, Duan ZJ, Tepper CG, Xue L, Chen X et al. Histone methyltransferase NSD2/MMSET mediates constitutive NF-kappaB signaling for cancer cell proliferation, survival, and tumor growth via a feed-forward loop. Mol Cell Biol 2012; 32: 3121-3131.
-
(2012)
Mol Cell Biol
, vol.32
, pp. 3121-3131
-
-
Yang, P.1
Guo, L.2
Duan, Z.J.3
Tepper, C.G.4
Xue, L.5
Chen, X.6
-
82
-
-
33646848438
-
Substrate preferences of the EZH2 histone methyltransferase complex
-
Martin C, Cao R, Zhang Y. Substrate preferences of the EZH2 histone methyltransferase complex. The J Biol Chem 2006; 281: 8365-8370.
-
(2006)
The J Biol Chem
, vol.281
, pp. 8365-8370
-
-
Martin, C.1
Cao, R.2
Zhang, Y.3
-
83
-
-
67349203626
-
Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer
-
van Haaften G, Dalgliesh GL, Davies H, Chen L, Bignell G, Greenman C et al. Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer. Nat Genet 2009; 41: 521-523.
-
(2009)
Nat Genet
, vol.41
, pp. 521-523
-
-
Van Haaften, G.1
Dalgliesh, G.L.2
Davies, H.3
Chen, L.4
Bignell, G.5
Greenman, C.6
-
85
-
-
84887108791
-
Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic Leukemia
-
Jaffe JD, Wang Y, Chan HM, Zhang J, Huether R, Kryukov GV et al. Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia. Nat Genet 2013; 45: 1386-1391.
-
(2013)
Nat Genet
, vol.45
, pp. 1386-1391
-
-
Jaffe, J.D.1
Wang, Y.2
Chan, H.M.3
Zhang, J.4
Huether, R.5
Kryukov, G.V.6
|