Structure-function insights reveal the human ribosome as a cancer target for antibiotics

Nature Communications

Volumn 7, Issue , 2016, Pages

  Myasnikov, Alexander G ^a,b,c,d   Kundhavai Natchiar, S ^a,b,c,d   Nebout, Marielle ^e,f   Hazemann, Isabelle ^a,b,c,d   Imbert, Véronique ^e,f   Khatter, Heena ^a,b,c,d,g   Peyron, Jean François ^e,f   Klaholz, Bruno P ^a,b,c,d  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b CNRS   (France)

^c INSERM   (France)

^d UNIVERSITÉ DE STRASBOURG   (France)

^e CENTRE MÉDITERRANÉEN DE MÉDECINE MOLÉCULAIRE C3M   (France)

^f UNIVERSITÉ CÔTE D'AZUR   (France)

^g EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANISOMYCIN; ANTIBIOTIC AGENT; BIOLOGICAL MARKER; CYCLOHEXIMIDE; CYCLOOXYGENASE 2; GENTAMICIN; HEAT SHOCK PROTEIN 90; HOMOHARRINGTONINE; KANAMYCIN; MYC PROTEIN; PROTEIN MCL 1; STREPTOMYCIN; TETRACYCLINE; VERRUCARIN A; VOMITOXIN;

ANTIBIOTICS; CANCER; CELLS AND CELL COMPONENTS; MITOCHONDRION; PROTEIN;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL LINE; CYTOSOL; EUKARYOTE; HUMAN; HUMAN CELL; LEUKEMIA CELL; LIGAND BINDING; MITOCHONDRIAL RIBOSOME; MOUSE; NONHUMAN; RIBOSOME; RIBOSOME SUBUNIT; STRUCTURE ANALYSIS;

BACTERIA (MICROORGANISMS); EUKARYOTA;

EID: 84989220413     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms12856     Document Type: Article

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